Context-dependent effects of genome-wide association study genotypes and macroenvironment on time to biochemical (prostate specific antigen) failure after prostatectomy

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 9, 2010, Pages 2115-2123

  Rebbeck, Timothy R ^a,b   Weber, Anita L ^a   Walker, Amy H ^a   Stefflova, Klara ^a   Tran, Teo V ^a   Spangler, Elaine ^a   Chang, Bao Li ^a   Zeigler Johnson, Charnita M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; BIOCHEMISTRY; CLINICAL ASSESSMENT; COHORT ANALYSIS; DNA EXTRACTION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOMICS; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HOUSEHOLD; HOUSING; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR EPIDEMIOLOGY; ONSET AGE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; PROSTATE CANCER; PROSTATECTOMY; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MOLECULAR EPIDEMIOLOGY; PROSPECTIVE STUDIES; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS; RISK FACTORS; TREATMENT FAILURE; UNITED STATES;

EID: 77956511215     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0173     Document Type: Article

References (41)

1. NIH Centers for Population Health and Health Disparities. From cells to society: overcoming health disparities. Bethesda (MD): National Cancer Institute; 2007.
2. Longford NT. Multilevel statistical models. New York: Oxford University Press; 1995.
3. Raudenbush SW, Bryk AS. Hierarchical linear modelling. 2nd ed. Newbury Park (CA): Sage Publications; 2001.
4. Snijders T, Bosker R. Multilevel analysis: an introduction to basic and advanced multilevel modelling. London: Sage; 1998.
5. Holmes JH, Lehman A, Hade E, et al. Challenges for multilevel health disparities research in a transdisciplinary environment. Am J Prev Med 2008;35:S182-92.
6. Graham H. Social determinants and their unequal distribution: clarifying policy understandings. Milbank Q 2004;82:101-24. (Pubitemid 38507310)
7. Vallgarda S. Social inequality in health: dichotomy or gradient? A comparative study of problematizations in national public health programmes. Health Policy 2008;85:71-82. (Pubitemid 350137519)
8. Hsing AW, Devesa SS. Trends and patterns of prostate cancer: what do they suggest? Epidemiol Rev 2001;23:3-13.
9. Hoffman RM, Gilliland FD, Eley JW, et al. Racial and ethnic differences in advanced-stage prostate cancer: the Prostate Cancer Outcomes Study. J Natl Cancer Inst 2001;93:388-95.
10. Casey G, Neville PJ, Plummer SJ, et al. RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet 2002;32:581-3. (Pubitemid 35435169)
11. Nwosu V, Carpten J, Trent JM, Sheridan R. Heterogeneity of genetic alterations in prostate cancer: evidence of the complex nature of the disease. Hum Mol Genet 2001;10:2313-8. (Pubitemid 32998847)
12. Richards B, Skoletsky J, Shuber AP, et al. Multiplex PCR amplification from the CFTR gene using DNA prepared from buccal brushes/swabs. Hum Mol Genet 1993;2:159-63. (Pubitemid 23075654)
13. Walker AH, Najarian D, White DL, Jaffe JF, Kanetsky PA, Rebbeck TR. Collection of genomic DNA by buccal swabs for polymerase chain reaction-based biomarker assays. Environ Health Perspect 1999;107:517-20. (Pubitemid 29371032)
14. Easton DF, Eeles RA. Genome-wide association studies in cancer. Hum Mol Genet 2008;17:R109-15.
15. Eeles RA, Kote-Jarai Z, Giles GG, et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet 2008;40:316-21.
16. Amundadottir LT, Sulem P, Gudmundsson J, et al. A common variant associated with prostate cancer in European and African populations. Nat Genet 2006;38:652-8.
17. Yeager M, Orr N, Hayes RB, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007;39:645-9.
18. Gudmundsson J, Sulem P, Manolescu A, et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 2007;39:631-7. (Pubitemid 46676102)
19. Thomas G, Jacobs KB, Yeager M, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet 2008;40:310-5. (Pubitemid 351311773)
20. Gudmundsson J, Sulem P, Steinthorsdottir V, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 2007;39:977-83.
21. Sun J, Purcell L, Gao Z, et al. Association between sequence variants at 17q12 and 17q24.3 and prostate cancer risk in European and African Americans. Prostate 2008;68:691-7. (Pubitemid 351632941)
22. Gudmundsson J, Sulem P, Rafnar T, et al. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet 2008;40:281-3.
23. Xu J, Zheng SL, Komiya A, et al. Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet 2002;32:321-5.
24. Subramanian SV, Lochner KA, Kawachi I. Neighborhood differences in social capital: a compositional artifact or a contextual construct? Health Place 2003;9:33-44.
25. Raudenbush S. The quantitative assessment of neighborhood social environments. In: Kawachi I, Berkman LF, editors. Neighborhoods and health. Princeton (NJ): Princeton University Press; 2003.
26. Krieger N, Williams DR, Moss NE. Measuring social class in US public health research: concepts, methodologies, and guidelines. Annu Rev Public Health 1997;18:341-78. (Pubitemid 27194075)
27. Krieger N, Ziehler S, Hogan JW, et al. Geocoding and measurement of neighborhood socioeconomic position: a US perspective. In: Kawachi I, Berkman LF, editors. Neighborhoods and health. Princeton (NJ): Princeton University Press; 2003.
28. Lin DY, Wei LJ. The robust inference for the Cox proportional hazards model. J Am Stat Assoc 1989;84:1074-8.
29. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 1995;57:289-300.
30. Kader AK, Sun J, Isaacs SD, et al. Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients. Prostate 2009;69:1195-205.
31. Salinas CA, Koopmeiners JS, Kwon EM, et al. Clinical utility of five genetic variants for predicting prostate cancer risk and mortality. Prostate 2009;69:363-72.
32. Zheng SL, Sun J, Wiklund F, et al. Cumulative association of five genetic variants with prostate cancer. N Engl J Med 2008;358:910-9. (Pubitemid 351397090)
33. Waters KM, Le Marchand L, Kolonel LN, et al. Generalizability of associations from prostate cancer genome-wide association studies in multiple populations. Cancer Epidemiol Biomarkers Prev 2009;18:1285-9.
34. Winckler W, Weedon MN, Graham RR, et al. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 2007;56:685-93. (Pubitemid 46348464)
35. Anahi Franchi N, Avendano C, Molina RI, et al. β-Microseminoprotein in human spermatozoa and its potential role in male fertility. Reproduction 2008;136:157-66.
36. Nam RK, Reeves JR, Toi A, et al. A novel serum marker, total prostate secretory protein of 94 amino acids, improves prostate cancer detection and helps identify high grade cancers at diagnosis. J Urol 2006;175:1291-7. (Pubitemid 43312972)
37. Reeves JR, Dulude H, Panchal C, Daigneault L, Ramnani DM. Prognostic value of prostate secretory protein of 94 amino acids and its binding protein after radical prostatectomy. Clin Cancer Res 2006;12:6018-22. (Pubitemid 44703763)
38. Kote-Jarai Z, Easton DF, Stanford JL, et al. Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium. Cancer Epidemiol Biomarkers Prev 2008;17:2052-61.
39. Sun J, Zheng SL, Wiklund F, et al. Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet 2008;40:1153-5.
40. Davey Smith G, Ebrahim S. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003;32:1-22.
41. Gatrell AC. On the spatial representation and accuracy of address-based data in the UK. Int J Geogr Inf Syst 1989;3.