RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

Nature Genetics

Volumn 32, Issue 4, 2002, Pages 581-583

  Casey, Graham ^a   Neville, Phillippa J ^a   Plummer, Sarah J ^a   Xiang, Ying ^a   Krumroy, Lisa M ^a   Klein, Eric A ^a   Catalona, William J ^b   Nupponen, Nina ^c   Carpten, John D ^c   Trent, Jeffrey M ^c   Silverman, Robert H ^a   Witte, John S ^d  

^a LERNER RESEARCH INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENCODING RIBONUCLEASE L; RIBONUCLEASE; UNCLASSIFIED DRUG;

AGED; ALLELE; ARTICLE; CANCER RISK; CONTROLLED STUDY; ENZYME ACTIVITY; FAMILY HISTORY; GENE; GENE MUTATION; HETEROZYGOSITY; HOMOZYGOTE; HPC1 GENE; HUMAN; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN VARIANT;

AGED; AMINO ACID SUBSTITUTION; ARGININE; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; ENDORIBONUCLEASES; GENE DELETION; GENE DOSAGE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MIDDLE AGED; PEDIGREE; POINT MUTATION; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS;

EID: 18744388563     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1021     Document Type: Article

References (12)

1. Hassel, B.A. et al. EMBO. J. 12, 3297-3304 (1993).
2. Zhou, A. et al. EMBO. J 16, 6355-6363 (1997).
3. Kerr, I.M. & Brown, R.E. Proc. Natl. Acad. Sci. USA 75, 256-260 (1978).
4. Carpten, J. et al. Nature Genet. 30, 181-184 (2002).
5. Newton, C.R. et al. Nucleic Acids Res. 17, 2503-2516 (1989).
6. Ferrie, R.M. et al. Am. J. Hum. Genet. 51, 251-262 (1992).
7. Greenland, S. & Robins, J.M. Am. J. Epidemiol. 128, 1185-1197 (1988).
8. Eeles, R.A. et al. Am. J. Hum. Genet. 62, 653-658 (1998).
9. Xu, J. Am. J. Hum. Genet. 66, 945-957 (2000).
10. Rennert, H. et al. Am. J. Hum. Genet. 71, 981-984 (2002).
11. Rokman, A. et al. Am. J. Hum. Genet. 70, 1299-1304 (2002).
12. Wang, L. et al. Am. J. Hum. Genet. 71, 116-123 (2002).