Recycling the versatile pipecolic linker

Journal of Combinatorial Chemistry

Volumn 12, Issue 5, 2010, Pages 747-753

  Zajdel, Pawel ^a,b   Masurier, Nicolas ^a   Sanchez, Pierre ^a   Pawlowski, MacIej ^b   Kreiter, Aude ^a   Nomezine, Gaël ^a   Enjalbal, Christine ^a   Amblard, Muriel ^a   Martinez, Jean ^a   Subra, Gilles ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

PIPECOLIC ACID DERIVATIVE; TRIFLUOROACETIC ACID;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS;

COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; MOLECULAR STRUCTURE; PIPECOLIC ACIDS; STEREOISOMERISM; TRIFLUOROACETIC ACID;

EID: 77956507297     PISSN: 15204766     EISSN: 15204774     Source Type: Journal    
DOI: 10.1021/cc100099z     Document Type: Article

References (10)

1. Urban, J., Vaisar, T., Shen, R., and Lee, M. S. Int. J. Pept. Protein Res. 1996, 47, 182-189
2. Rubini, C., Osler, A., Calderan, A., Guiotto, A., and Ruzza, P. J. Pept. Sci. 2008, 14, 989-997
3. Zajdel, P., Subra, G., Bojarski, A. J., Duszynska, B., Pawlowski, M., and Martinez, J. J. Comb. Chem. 2004, 6, 761-767
4. Creighton, C. J., Romoff, T. T., Bu, J. H., and Goodman, M. J. Am. Chem. Soc. 1999, 121, 6786-6791
5. Sobolewski, D., Prahl, A., Kwiatkowska, A., Slaninova, J., and Lammek, B. J. Pept. Sci. 2009, 15, 161-165
6. Zajdel, P., Nomezine, G., Masurier, N., Amblard, M., Pawlowski, M., Martinez, J., and Subra, G. Chem. - Eur. J. 2010, 16, 7547-7553
7. Amblard, M., Fehrentz, J. A., Martinez, J., and Subra, G. Mol. Biotechnol. 2006, 33, 239-254
8. Giovannoni, J., Subra, G., Amblard, M., and Martinez, J. Tetrahedron Lett. 2001, 42, 5389-5392
9. A contaminant at RT = 1.53 min was detected in all experiments which correspond to the direct coupling of Fmoc diaminopropane on cyclohexane dicarboxylic acid witnessing that the coupling of pipecolic acid during the preparation of the linker was not complete.
10. See supplementary information of Rubini, C., Osler, A., Calderan, A., Guiotto, A., and Ruzza, P. J. Pept. Sci. 2008, 14, 989-997