-
1
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
Kuppers R. Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer 2005; 5:251-62.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 251-262
-
-
Kuppers, R.1
-
2
-
-
0035913362
-
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas
-
Pasqualucci L, Neumeister P, Goossens T, Nanjangud G, Chaganti RS, Kuppers R, Dalla-Favera R. Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas. Nature 2001; 412:341-6.
-
(2001)
Nature
, vol.412
, pp. 341-346
-
-
Pasqualucci, L.1
Neumeister, P.2
Goossens, T.3
Nanjangud, G.4
Chaganti, R.S.5
Kuppers, R.6
Dalla-Favera, R.7
-
3
-
-
0032797272
-
Chemokines and cell migration in secondary lymphoid organs
-
Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999; 286:2098-102.
-
(1999)
Science
, vol.286
, pp. 2098-2102
-
-
Cyster, J.G.1
-
4
-
-
2442606191
-
Lymphocyte trafficking across high endothelial venules: Dogmas and enigmas
-
Miyasaka M, Tanaka T. Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. Nat Rev Immunol 2004; 4:360-70.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 360-370
-
-
Miyasaka, M.1
Tanaka, T.2
-
5
-
-
0035257205
-
Lymphocyte traffic control by chemokines
-
Moser B, Loetscher P. Lymphocyte traffic control by chemokines. Nat Immunol 2001; 2:123-8.
-
(2001)
Nat Immunol
, vol.2
, pp. 123-128
-
-
Moser, B.1
Loetscher, P.2
-
6
-
-
0242551584
-
Homing and cellular traffic in lymph nodes
-
von Andrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol 2003; 3:867-78.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 867-878
-
-
Von Andrian, U.H.1
Mempel, T.R.2
-
7
-
-
50049102160
-
How chemokines invite leukocytes to dance
-
Thelen M, Stein JV. How chemokines invite leukocytes to dance. Nat Immunol 2008; 9:953-9.
-
(2008)
Nat Immunol
, vol.9
, pp. 953-959
-
-
Thelen, M.1
Stein, J.V.2
-
9
-
-
70349536006
-
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression
-
Meacham CE, Ho EE, Dubrovsky E, Gertler FB, Hemann MT. In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. Nat Genet 2009; 41:1133-7.
-
(2009)
Nat Genet
, vol.41
, pp. 1133-1137
-
-
Meacham, C.E.1
Ho, E.E.2
Dubrovsky, E.3
Gertler, F.B.4
Hemann, M.T.5
-
10
-
-
15044359236
-
Linking Rap to cell adhesion
-
Bos JL. Linking Rap to cell adhesion. Curr Opin Cell Biol 2005; 17:123-8.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 123-128
-
-
Bos, J.L.1
-
11
-
-
0032582646
-
Activation of the Rap1 GTPase by the B cell antigen receptor
-
McLeod SJ, Ingham RJ, Bos JL, Kurosaki T, Gold MR. Activation of the Rap1 GTPase by the B cell antigen receptor. J Biol Chem 1998; 273:29218-23.
-
(1998)
J Biol Chem
, vol.273
, pp. 29218-29223
-
-
McLeod, S.J.1
Ingham, R.J.2
Bos, J.L.3
Kurosaki, T.4
Gold, M.R.5
-
12
-
-
33747429094
-
The Rap GTPases mediate CXCL13- And sphingosine1-phosphate-induced chemotaxis, adhesion and Pyk2 tyrosine phosphorylation in B lymphocytes
-
Durand CA, Westendorf J, Tse KW, Gold MR. The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion and Pyk2 tyrosine phosphorylation in B lymphocytes. Eur J Immunol 2006; 36:2235-49.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2235-2249
-
-
Durand, C.A.1
Westendorf, J.2
Tse, K.W.3
Gold, M.R.4
-
13
-
-
37849031433
-
The Rap GTPases regulate B cell morphology, immune-synapse formation and signaling by particulate B cell receptor ligands
-
Lin KBL, Freeman SA, Zabetian S, Brugger H, Weber M, Lei V, et al. The Rap GTPases regulate B cell morphology, immune-synapse formation and signaling by particulate B cell receptor ligands. Immunity 2008; 28:75-87.
-
(2008)
Immunity
, vol.28
, pp. 75-87
-
-
Lin, K.B.L.1
Freeman, S.A.2
Zabetian, S.3
Brugger, H.4
Weber, M.5
Lei, V.6
-
14
-
-
0036681723
-
The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): Potential role for Rap2 in promoting B cell migration
-
McLeod SJ, Li AH, Lee RL, Burgess AE, Gold MR. The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration. J Immunol 2002; 169:1365-71.
-
(2002)
J Immunol
, vol.169
, pp. 1365-1371
-
-
McLeod, S.J.1
Li, A.H.2
Lee, R.L.3
Burgess, A.E.4
Gold, M.R.5
-
15
-
-
1842425828
-
The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization and Pyk2 tyrosine phosphorylation in B lymphocytes
-
McLeod SJ, Shum AJ, Lee RL, Takei F, Gold MR. The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization and Pyk2 tyrosine phosphorylation in B lymphocytes. J Biol Chem 2004; 279:12009-19.
-
(2004)
J Biol Chem
, vol.279
, pp. 12009-12019
-
-
McLeod, S.J.1
Shum, A.J.2
Lee, R.L.3
Takei, F.4
Gold, M.R.5
-
16
-
-
77956454205
-
The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas
-
in press
-
Lin KBL, Tan P, Freeman SA, Lam M, McNagny KM, Gold MR. The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas. Oncogene 2009; in press.
-
(2009)
Oncogene
-
-
Lin, K.B.L.1
Tan, P.2
Freeman, S.A.3
Lam, M.4
McNagny, K.M.5
Gold, M.R.6
-
17
-
-
0038561221
-
Rap1 translates chemokine signals to integrin activation, cell polarization and motility across vascular endothelium under flow
-
Shimonaka M, Katagiri K, Nakayama T, Fujita N, Tsuruo T, Yoshie O, Kinashi T. Rap1 translates chemokine signals to integrin activation, cell polarization and motility across vascular endothelium under flow. J Cell Biol 2003; 161:417-27.
-
(2003)
J Cell Biol
, vol.161
, pp. 417-427
-
-
Shimonaka, M.1
Katagiri, K.2
Nakayama, T.3
Fujita, N.4
Tsuruo, T.5
Yoshie, O.6
Kinashi, T.7
-
18
-
-
34250168972
-
Transcellular diapedesis is initiated by invasive podosomes
-
Carman CV, Sage PT, Sciuto TE, de la Fuente MA, Geha RS, Ochs HD, et al. Transcellular diapedesis is initiated by invasive podosomes. Immunity 2007; 26:784-97.
-
(2007)
Immunity
, vol.26
, pp. 784-797
-
-
Carman, C.V.1
Sage, P.T.2
Sciuto, T.E.3
De La Fuente, M.A.4
Geha, R.S.5
Ochs, H.D.6
-
19
-
-
33846847701
-
Rap1: A key regulator in cell-cell junction formation
-
Kooistra MR, Dube N, Bos JL. Rap1: a key regulator in cell-cell junction formation. J Cell Sci 2007; 120:17-22.
-
(2007)
J Cell Sci
, vol.120
, pp. 17-22
-
-
Kooistra, M.R.1
Dube, N.2
Bos, J.L.3
-
20
-
-
0042490495
-
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
-
Katagiri K, Maeda A, Shimonaka M, Kinashi T. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol 2003; 4:741-8.
-
(2003)
Nat Immunol
, vol.4
, pp. 741-748
-
-
Katagiri, K.1
Maeda, A.2
Shimonaka, M.3
Kinashi, T.4
-
21
-
-
33748454742
-
Reconstructing and deconstructing agonist-induced activation of integrin αIIbβ3
-
Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, et al. Reconstructing and deconstructing agonist-induced activation of integrin αIIbβ3. Curr Biol 2006; 16:1796-806.
-
(2006)
Curr Biol
, vol.16
, pp. 1796-1806
-
-
Han, J.1
Lim, C.J.2
Watanabe, N.3
Soriani, A.4
Ratnikov, B.5
Calderwood, D.A.6
-
22
-
-
66149128873
-
The tail of integrins, talin and kindlins
-
Moser M, Legate KR, Zent R, Fassler R. The tail of integrins, talin and kindlins. Science 2009; 324:895-9.
-
(2009)
Science
, vol.324
, pp. 895-899
-
-
Moser, M.1
Legate, K.R.2
Zent, R.3
Fassler, R.4
-
23
-
-
5444230311
-
Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors
-
Arthur WT, Quilliam LA, Cooper JA. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. J Cell Biol 2004; 167:111-22.
-
(2004)
J Cell Biol
, vol.167
, pp. 111-122
-
-
Arthur, W.T.1
Quilliam, L.A.2
Cooper, J.A.3
-
24
-
-
4344594485
-
The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity
-
Schwamborn JC, Puschel AW. The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 2004; 7:923-9.
-
(2004)
Nat Neurosci
, vol.7
, pp. 923-929
-
-
Schwamborn, J.C.1
Puschel, A.W.2
-
25
-
-
5044241734
-
RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion
-
Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, et al. RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev Cell 2004; 7:585-95.
-
(2004)
Dev Cell
, vol.7
, pp. 585-595
-
-
Lafuente, E.M.1
Van Puijenbroek, A.A.2
Krause, M.3
Carman, C.V.4
Freeman, G.J.5
Berezovskaya, A.6
-
26
-
-
0034254923
-
The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin
-
Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc Natl Acad Sci USA 2000; 97:9064-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9064-9069
-
-
Boettner, B.1
Govek, E.E.2
Cross, J.3
Van Aelst, L.4
-
27
-
-
69249089318
-
B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading
-
Tse KW, Dang-Lawson M, Lee RL, Vong D, Bulic A, Buckbinder L, Gold MR. B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading. J Biol Chem 2009; 284:22865-77.
-
(2009)
J Biol Chem
, vol.284
, pp. 22865-22877
-
-
Tse, K.W.1
Dang-Lawson, M.2
Lee, R.L.3
Vong, D.4
Bulic, A.5
Buckbinder, L.6
Gold, M.R.7
-
28
-
-
0034232062
-
Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
-
Guinamard R, Okigaki M, Schlessinger J, Ravetch JV. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat Immunol 2000; 1:31-6.
-
(2000)
Nat Immunol
, vol.1
, pp. 31-36
-
-
Guinamard, R.1
Okigaki, M.2
Schlessinger, J.3
Ravetch, J.V.4
-
29
-
-
33947283144
-
The Par polarity complex regulates Rap1- And chemokine-induced T cell polarization
-
Gerard A, Mertens AE, van der Kammen RA, Collard JG. The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization. J Cell Biol 2007; 176:863-75.
-
(2007)
J Cell Biol
, vol.176
, pp. 863-875
-
-
Gerard, A.1
Mertens, A.E.2
Van Der Kammen, R.A.3
Collard, J.G.4
-
30
-
-
14244260906
-
Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes
-
Fujita H, Fukuhara S, Sakurai A, Yamagishi A, Kamioka Y, Nakaoka Y, et al. Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes. J Biol Chem 2005; 280:5022-31.
-
(2005)
J Biol Chem
, vol.280
, pp. 5022-5031
-
-
Fujita, H.1
Fukuhara, S.2
Sakurai, A.3
Yamagishi, A.4
Kamioka, Y.5
Nakaoka, Y.6
-
31
-
-
33747623042
-
Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
-
Katagiri K, Imamura M, Kinashi T. Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion. Nat Immunol 2006; 7:919-28.
-
(2006)
Nat Immunol
, vol.7
, pp. 919-928
-
-
Katagiri, K.1
Imamura, M.2
Kinashi, T.3
-
32
-
-
37849000098
-
Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation
-
Arana E, Vehlow A, Harwood NE, Vigorito E, Henderson R, Turner M, et al. Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity 2008; 28:88-99.
-
(2008)
Immunity
, vol.28
, pp. 88-99
-
-
Arana, E.1
Vehlow, A.2
Harwood, N.E.3
Vigorito, E.4
Henderson, R.5
Turner, M.6
-
33
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002; 2:563-72.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
34
-
-
0035052462
-
VLA-4 mediated adhesion to bone marrow stromal cells confers chemoresistance to adherent lymphoma cells
-
Weekes CD, Kuszynski CA, Sharp JG. VLA-4 mediated adhesion to bone marrow stromal cells confers chemoresistance to adherent lymphoma cells. Leuk Lymphoma 2001; 40:631-45.
-
(2001)
Leuk Lymphoma
, vol.40
, pp. 631-645
-
-
Weekes, C.D.1
Kuszynski, C.A.2
Sharp, J.G.3
-
35
-
-
0032894509
-
Survival signals within the tumour microenvironment suppress drug-induced apoptosis: Lessons learned from B lymphomas
-
Taylor ST, Hickman JA, Dive C. Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas. Endocrine-Related Cancer 1999; 6:21-3.
-
(1999)
Endocrine-Related Cancer
, vol.6
, pp. 21-23
-
-
Taylor, S.T.1
Hickman, J.A.2
Dive, C.3
-
36
-
-
33845501828
-
Role of phosphatidylinositol 3′-kinase/AKT pathway in diffuse large B-cell lymphoma survival
-
Uddin S, Hussain AR, Siraj AK, Manogaran PS, Al-Jomah NA, Moorji A, et al. Role of phosphatidylinositol 3′-kinase/AKT pathway in diffuse large B-cell lymphoma survival. Blood 2006; 108:4178-86.
-
(2006)
Blood
, vol.108
, pp. 4178-4186
-
-
Uddin, S.1
Hussain, A.R.2
Siraj, A.K.3
Manogaran, P.S.4
Al-Jomah, N.A.5
Moorji, A.6
-
37
-
-
61949240364
-
A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans
-
Malinin NL, Zhang L, Choi J, Ciocea A, Razorenova O, Ma YQ, et al. A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. Nat Med 2009; 15:313-8.
-
(2009)
Nat Med
, vol.15
, pp. 313-318
-
-
Malinin, N.L.1
Zhang, L.2
Choi, J.3
Ciocea, A.4
Razorenova, O.5
Ma, Y.Q.6
-
38
-
-
61949352480
-
Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells
-
Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, et al. Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med 2009; 15:300-5.
-
(2009)
Nat Med
, vol.15
, pp. 300-305
-
-
Moser, M.1
Bauer, M.2
Schmid, S.3
Ruppert, R.4
Schmidt, S.5
Sixt, M.6
-
39
-
-
61949086409
-
Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation
-
Svensson L, Howarth K, McDowall A, Patzak I, Evans R, Ussar S, et al. Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nat Med 2009; 15:306-12.
-
(2009)
Nat Med
, vol.15
, pp. 306-312
-
-
Svensson, L.1
Howarth, K.2
McDowall, A.3
Patzak, I.4
Evans, R.5
Ussar, S.6
-
40
-
-
35648963605
-
Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration
-
Miertzschke M, Stanley P, Bunney TD, Rodrigues-Lima F, Hogg N, Katan M. Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration. J Biol Chem 2007; 282:30629-42.
-
(2007)
J Biol Chem
, vol.282
, pp. 30629-30642
-
-
Miertzschke, M.1
Stanley, P.2
Bunney, T.D.3
Rodrigues-Lima, F.4
Hogg, N.5
Katan, M.6
-
41
-
-
47149093727
-
A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development
-
Chen Y, Yu M, Podd A, Wen R, Chrzanowska-Wodnicka M, White GC, Wang D. A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood 2008; 111:4627-36.
-
(2008)
Blood
, vol.111
, pp. 4627-4636
-
-
Chen, Y.1
Yu, M.2
Podd, A.3
Wen, R.4
Chrzanowska-Wodnicka, M.5
White, G.C.6
Wang, D.7
-
42
-
-
51549097602
-
Rap1b regulates B cell development, homing and T cell-dependent humoral immunity
-
Chu H, Awasthi A, White GC, Chrzanowska-Wodnicka M, Malarkannan S. Rap1b regulates B cell development, homing and T cell-dependent humoral immunity. J Immunol 2008; 181:3373-83.
-
(2008)
J Immunol
, vol.181
, pp. 3373-3383
-
-
Chu, H.1
Awasthi, A.2
White, G.C.3
Chrzanowska-Wodnicka, M.4
Malarkannan, S.5
-
43
-
-
4644221351
-
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation
-
Crittenden JR, Bergmeier W, Zhang Y, Piffatgh CL, Liang Y, Wagner DD, et al. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med 2004; 10:982-6.
-
(2004)
Nat Med
, vol.10
, pp. 982-986
-
-
Crittenden, J.R.1
Bergmeier, W.2
Zhang, Y.3
Piffatgh, C.L.4
Liang, Y.5
Wagner, D.D.6
-
44
-
-
14644400415
-
Rap1b is required for normal platelet function and hemostasis in mice
-
Chrzanowska-Wodnicka M, Smyth SS, Schoenwaelder SM, Fischer TH, White GC. Rap1b is required for normal platelet function and hemostasis in mice. J Clin Invest 2005; 115:680-7.
-
(2005)
J Clin Invest
, vol.115
, pp. 680-687
-
-
Chrzanowska-Wodnicka, M.1
Smyth, S.S.2
Schoenwaelder, S.M.3
Fischer, T.H.4
White, G.C.5
-
45
-
-
67449124367
-
Activation of Rap1 promotes prostate cancer metastasis
-
Bailey CL, Kelly P, Casey PJ. Activation of Rap1 promotes prostate cancer metastasis. Cancer Res 2009; 69:4962-8.
-
(2009)
Cancer Res
, vol.69
, pp. 4962-4968
-
-
Bailey, C.L.1
Kelly, P.2
Casey, P.J.3
-
46
-
-
31544478790
-
Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer
-
Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, et al. Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer. Cancer Res 2006; 66:898-906.
-
(2006)
Cancer Res
, vol.66
, pp. 898-906
-
-
Zhang, L.1
Chenwei, L.2
Mahmood, R.3
Van Golen, K.4
Greenson, J.5
Li, G.6
|