메뉴 건너뛰기




Volumn 89, Issue 2, 2010, Pages 197-203

Evaluation of COX-2, EGFR, and p53 as biomarkers of non-dysplastic oral leukoplakias

Author keywords

COX 2; EGFR; Molecular marker; Oral leukoplakia; P53; Quantitative real time PCR

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; PROTEIN P53; TOBACCO SMOKE; BIOLOGICAL MARKER; PTGS2 PROTEIN, HUMAN;

EID: 77956450009     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.06.004     Document Type: Article
Times cited : (16)

References (63)
  • 1
    • 4544263107 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity
    • Akita Y., Kozaki K., Nakagawa A., et al. Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity. Br. J. Dermatol. 2004, 151:472-480.
    • (2004) Br. J. Dermatol. , vol.151 , pp. 472-480
    • Akita, Y.1    Kozaki, K.2    Nakagawa, A.3
  • 2
    • 30344439138 scopus 로고    scopus 로고
    • Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy
    • Ali S., El-Rayes B.F., Sarkar F.H., et al. Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy. Mol. Cancer Ther. 2005, 4:1943-1951.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1943-1951
    • Ali, S.1    El-Rayes, B.F.2    Sarkar, F.H.3
  • 3
    • 3042759696 scopus 로고    scopus 로고
    • COX-2 inhibition in upper aerodigestive tract tumors
    • Altorki N.K., Subbaramaiah K., Dannenberg A.J. COX-2 inhibition in upper aerodigestive tract tumors. Semin. Oncol. 2004, 31(2 Suppl 7):30-36.
    • (2004) Semin. Oncol. , vol.31 , Issue.2 SUPPL 7 , pp. 30-36
    • Altorki, N.K.1    Subbaramaiah, K.2    Dannenberg, A.J.3
  • 4
    • 39749178365 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer
    • Aparicio G., Prado D., Jiménez Fonseca P., et al. Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer. Clin. Transl. Oncol. 2007, 9:694-702.
    • (2007) Clin. Transl. Oncol. , vol.9 , pp. 694-702
    • Aparicio, G.1    Prado, D.2    Jiménez Fonseca, P.3
  • 5
    • 0038718635 scopus 로고    scopus 로고
    • Deregulated cyclooxygenase-2 expression in oral premalignant tissues
    • Banerjee A.G., Gopalakrishnan V.K., Bhattacharya I., et al. Deregulated cyclooxygenase-2 expression in oral premalignant tissues. Mol. Cancer Ther. 2002, 1:1265-1271.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 1265-1271
    • Banerjee, A.G.1    Gopalakrishnan, V.K.2    Bhattacharya, I.3
  • 6
    • 0018860221 scopus 로고
    • Prostaglandin/like material extracted from squamous cell carcinomas of the head and neck
    • Bennett A., Carter R.L., Stamford I.F., et al. Prostaglandin/like material extracted from squamous cell carcinomas of the head and neck. Br. J. Cancer 1980, 41:204-208.
    • (1980) Br. J. Cancer , vol.41 , pp. 204-208
    • Bennett, A.1    Carter, R.L.2    Stamford, I.F.3
  • 7
    • 0034633638 scopus 로고    scopus 로고
    • Intracellular unesterified arachidonic acid signals apoptosis
    • Cao T., Pearman A.T., Zimmerman G.A., et al. Intracellular unesterified arachidonic acid signals apoptosis. Proc. Natl Acad. Sci. 2000, 97:11280-11285.
    • (2000) Proc. Natl Acad. Sci. , vol.97 , pp. 11280-11285
    • Cao, T.1    Pearman, A.T.2    Zimmerman, G.A.3
  • 8
    • 0036157485 scopus 로고    scopus 로고
    • Many actions of cyclooxygenase-2 in cell dynamics and in cancer
    • Cao Y., Prescott S.M. Many actions of cyclooxygenase-2 in cell dynamics and in cancer. J. Cell. Physiol. 2002, 190:279-286.
    • (2002) J. Cell. Physiol. , vol.190 , pp. 279-286
    • Cao, Y.1    Prescott, S.M.2
  • 9
    • 0033105360 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is upregulated in squamous cell carcinoma of the head and neck
    • Chan G., Boyle J.O., Yang E.K., et al. Cyclooxygenase-2 expression is upregulated in squamous cell carcinoma of the head and neck. Cancer Res. 1999, 59:991-994.
    • (1999) Cancer Res. , vol.59 , pp. 991-994
    • Chan, G.1    Boyle, J.O.2    Yang, E.K.3
  • 10
    • 0031882916 scopus 로고    scopus 로고
    • Mechanisms underlying non-steroidal anti-inflammatory drug-mediated apoptosis
    • Chan T.A., Morin P.J., Vogelstein B., et al. Mechanisms underlying non-steroidal anti-inflammatory drug-mediated apoptosis. PNAS 1998, 95:681-686.
    • (1998) PNAS , vol.95 , pp. 681-686
    • Chan, T.A.1    Morin, P.J.2    Vogelstein, B.3
  • 11
    • 36749046814 scopus 로고    scopus 로고
    • Wnt signaling controls radiosensitivity via cyclooxygenases-2-mediated Ku expression in head and neck cancer
    • Chang H.W., Roh J.L., Jeong E.J., et al. Wnt signaling controls radiosensitivity via cyclooxygenases-2-mediated Ku expression in head and neck cancer. Int. J. Cancer 2008, 122:100-107.
    • (2008) Int. J. Cancer , vol.122 , pp. 100-107
    • Chang, H.W.1    Roh, J.L.2    Jeong, E.J.3
  • 12
    • 33644685671 scopus 로고    scopus 로고
    • Interaction between epidermal growth factor receptor and cyclooxygenase 2 mediated pathways and its implications for the chemoprevention of head and neck cancer
    • Choe M.S., Zhang X., Shin H.J.C., et al. Interaction between epidermal growth factor receptor and cyclooxygenase 2 mediated pathways and its implications for the chemoprevention of head and neck cancer. Mol. Cancer Ther. 2005, 4:1448-1455.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1448-1455
    • Choe, M.S.1    Zhang, X.2    Shin, H.J.C.3
  • 13
    • 0035683884 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2: an approach to preventing cancer of the upper aerodigestive tract
    • Dannenberg A.J., Altorki N.K., Boyle J.O., et al. Inhibition of cyclooxygenase-2: an approach to preventing cancer of the upper aerodigestive tract. Ann. NY Acad. Sci. 2001, 952:109-115.
    • (2001) Ann. NY Acad. Sci. , vol.952 , pp. 109-115
    • Dannenberg, A.J.1    Altorki, N.K.2    Boyle, J.O.3
  • 14
    • 13744254574 scopus 로고    scopus 로고
    • Cyclooxygenases-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention
    • Dannenberg A.J., Lippman S.M., Mann J.R., et al. Cyclooxygenases-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention. J. Clin. Oncol. 2005, 23:254-266.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 254-266
    • Dannenberg, A.J.1    Lippman, S.M.2    Mann, J.R.3
  • 15
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in human neoplasia: rationale and promise
    • Dannenberg A.J., Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. Cancer Cell 2003, 4:431-436.
    • (2003) Cancer Cell , vol.4 , pp. 431-436
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 16
    • 42549167966 scopus 로고    scopus 로고
    • Genetic polymorphisms of carcinogen metabolizing enzymes are associated with oral leukoplakia development and p53 overexpression
    • Duarte E.C., Ribeiro D.C., Gomez M.V., et al. Genetic polymorphisms of carcinogen metabolizing enzymes are associated with oral leukoplakia development and p53 overexpression. Anticancer Res. 2008, 28:1101-1106.
    • (2008) Anticancer Res. , vol.28 , pp. 1101-1106
    • Duarte, E.C.1    Ribeiro, D.C.2    Gomez, M.V.3
  • 17
    • 30844452690 scopus 로고    scopus 로고
    • Immunohistochemical analysis of P57(kip2), p53 and hsp60 expressions in premalignant and malignant oral tissues
    • Fan G.-K., Chen J., Ping F., et al. Immunohistochemical analysis of P57(kip2), p53 and hsp60 expressions in premalignant and malignant oral tissues. Oral Oncol. 2006, 42:147-153.
    • (2006) Oral Oncol. , vol.42 , pp. 147-153
    • Fan, G.-K.1    Chen, J.2    Ping, F.3
  • 18
    • 77956422059 scopus 로고    scopus 로고
    • GeNorm VBA applet for Microsoft Excel [Excel macro on Internet] [cited July 2006]. Available from
    • GeNorm VBA applet for Microsoft Excel [Excel macro on Internet] [cited July 2006]. Available from http://medgen.ugent.be/-jvdescomp/genorm/.
  • 19
    • 0017658218 scopus 로고
    • Suppression of human T-cell mitogenesis by prostaglandin: existence of a prostaglandin producing suppressor cell
    • Goodwin J.S., Bankhurst A.D., Messner R.P. Suppression of human T-cell mitogenesis by prostaglandin: existence of a prostaglandin producing suppressor cell. J. Exp. Med. 1977, 146:1719-1731.
    • (1977) J. Exp. Med. , vol.146 , pp. 1719-1731
    • Goodwin, J.S.1    Bankhurst, A.D.2    Messner, R.P.3
  • 20
    • 0021043226 scopus 로고
    • Regulation of immune response by prostaglandins
    • Goodwin J.S., Geuppens J.L. Regulation of immune response by prostaglandins. J. Clin. Immunol. 1983, 3:295-315.
    • (1983) J. Clin. Immunol. , vol.3 , pp. 295-315
    • Goodwin, J.S.1    Geuppens, J.L.2
  • 21
    • 0013650320 scopus 로고    scopus 로고
    • Asynchronous modulation of transforming growth factor α and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma
    • Grandis J.R., Tweardy D.J., Melhem M.F. Asynchronous modulation of transforming growth factor α and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma. Clin. Cancer Res. 1998, 4:13-20.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 13-20
    • Grandis, J.R.1    Tweardy, D.J.2    Melhem, M.F.3
  • 22
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy
    • Herbst R.S., Shin D.M. Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy. Cancer 2002, 94:1593-1611.
    • (2002) Cancer , vol.94 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2
  • 23
    • 34247361698 scopus 로고    scopus 로고
    • Oral premalignant lesions: is a biopsy reliable?
    • Holmstrup P., Vedtofte P., Reibel J., et al. Oral premalignant lesions: is a biopsy reliable?. J. Oral Pathol. Med. 2007, 36:262-266.
    • (2007) J. Oral Pathol. Med. , vol.36 , pp. 262-266
    • Holmstrup, P.1    Vedtofte, P.2    Reibel, J.3
  • 24
    • 0033119190 scopus 로고    scopus 로고
    • Transcriptional activation of cyclooxygenase-2 in Wnt-1 transformed mouse mammary epithelial cells
    • Howe L.R., Subbaramaiah K., Chung W.J., et al. Transcriptional activation of cyclooxygenase-2 in Wnt-1 transformed mouse mammary epithelial cells. Cancer Res. 1999, 59:1572-1577.
    • (1999) Cancer Res. , vol.59 , pp. 1572-1577
    • Howe, L.R.1    Subbaramaiah, K.2    Chung, W.J.3
  • 25
    • 0021997591 scopus 로고
    • Prostaglandins in squamous cell carcinoma of the head and neck: a preliminary study
    • Jung T.K., Berlinger N.T., Juhn S.K. Prostaglandins in squamous cell carcinoma of the head and neck: a preliminary study. Laryngoscope 1985, 95:307-312.
    • (1985) Laryngoscope , vol.95 , pp. 307-312
    • Jung, T.K.1    Berlinger, N.T.2    Juhn, S.K.3
  • 26
    • 0346058328 scopus 로고    scopus 로고
    • Changes in apoptosis and mitotic index, p53 and ki67 expression in various types of oral leukoplakia
    • Kövesi G., Szende B. Changes in apoptosis and mitotic index, p53 and ki67 expression in various types of oral leukoplakia. Oncology 2003, 65:331-336.
    • (2003) Oncology , vol.65 , pp. 331-336
    • Kövesi, G.1    Szende, B.2
  • 27
    • 0141537956 scopus 로고    scopus 로고
    • Immunohistochemical study of syndecan-1 downregulation and the expression of p53 protein or ki-67 antigen in oral leukoplakia with or without epithelial dysplasia
    • Kurokawa H., Matsumoto S., Murata T., et al. Immunohistochemical study of syndecan-1 downregulation and the expression of p53 protein or ki-67 antigen in oral leukoplakia with or without epithelial dysplasia. J. Oral Pathol. Med. 2003, 32:513-521.
    • (2003) J. Oral Pathol. Med. , vol.32 , pp. 513-521
    • Kurokawa, H.1    Matsumoto, S.2    Murata, T.3
  • 28
    • 58049175516 scopus 로고    scopus 로고
    • PCNA and p53 expression in oral leukoplakia with different degrees of keratinisation
    • Lawall M.A., Crivelini M.M. PCNA and p53 expression in oral leukoplakia with different degrees of keratinisation. J. Appl. Oral Sci. 2006, 14:276-280.
    • (2006) J. Appl. Oral Sci. , vol.14 , pp. 276-280
    • Lawall, M.A.1    Crivelini, M.M.2
  • 29
    • 13744259558 scopus 로고    scopus 로고
    • Oral cancer prevention and the evolution of molecular-targeted drug development
    • Lippman S.M., Sudbo J., Hong W.K. Oral cancer prevention and the evolution of molecular-targeted drug development. J. Clin. Oncol. 2005, 23:346-356.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 346-356
    • Lippman, S.M.1    Sudbo, J.2    Hong, W.K.3
  • 31
    • 0036123176 scopus 로고    scopus 로고
    • Aplicaciones clínicas del diagnóstico de las alteraciones de p53 en el carcinoma escamoso de cabeza y cuello (p53 en el CECC)
    • López-Martínez M., Anzola M., Cuevas N., et al. Aplicaciones clínicas del diagnóstico de las alteraciones de p53 en el carcinoma escamoso de cabeza y cuello (p53 en el CECC). Med. Oral 2002, 7:108-120.
    • (2002) Med. Oral , vol.7 , pp. 108-120
    • López-Martínez, M.1    Anzola, M.2    Cuevas, N.3
  • 32
    • 0001913959 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2expression An approach to preventing head and neck cancer
    • Mestre J.R., Chan G., Zhang F., et al. Inhibition of cyclooxygenase-2expression An approach to preventing head and neck cancer. Ann N Y Acad Sci 1999, 889:62-71.
    • (1999) Ann N Y Acad Sci , vol.889 , pp. 62-71
    • Mestre, J.R.1    Chan, G.2    Zhang, F.3
  • 33
    • 0038460053 scopus 로고    scopus 로고
    • Carcinogenesis and cyclooxygenase: the potential role of COX-2 inhibition in upper aerodigestive tract cancer
    • Mohan S., Epstein J.B. Carcinogenesis and cyclooxygenase: the potential role of COX-2 inhibition in upper aerodigestive tract cancer. Oral Oncol. 2003, 39:537-546.
    • (2003) Oral Oncol. , vol.39 , pp. 537-546
    • Mohan, S.1    Epstein, J.B.2
  • 34
    • 19944432973 scopus 로고    scopus 로고
    • Levels of Cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands
    • Moraitis D., Du B., de Lorenzo M.S., et al. Levels of Cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer Res. 2005, 65:664-670.
    • (2005) Cancer Res. , vol.65 , pp. 664-670
    • Moraitis, D.1    Du, B.2    de Lorenzo, M.S.3
  • 35
    • 0033638813 scopus 로고    scopus 로고
    • An experimental model of tumor dormancy therapy for advanced head and neck carcinoma
    • Nishimura G., Yanoma S., Satake K., et al. An experimental model of tumor dormancy therapy for advanced head and neck carcinoma. Jpn J. Cancer Res. 2000, 91:1199-1203.
    • (2000) Jpn J. Cancer Res. , vol.91 , pp. 1199-1203
    • Nishimura, G.1    Yanoma, S.2    Satake, K.3
  • 36
    • 41249086806 scopus 로고    scopus 로고
    • Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation
    • Pandey M., Prakash O., Santhi W.S., et al. Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation. Int. J. Oral Maxillofac. Surg. 2008, 37:379-383.
    • (2008) Int. J. Oral Maxillofac. Surg. , vol.37 , pp. 379-383
    • Pandey, M.1    Prakash, O.2    Santhi, W.S.3
  • 37
    • 0033757709 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy
    • Raymond E., Faivre S., Armand J.P. Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs 2000, 60:15-23.
    • (2000) Drugs , vol.60 , pp. 15-23
    • Raymond, E.1    Faivre, S.2    Armand, J.P.3
  • 38
    • 0036320304 scopus 로고    scopus 로고
    • Expression of cyclo-oxygenase-2 in human tongue carcinoma and its precursor lesions
    • Renkonen J., Wolff H., Paavonen T. Expression of cyclo-oxygenase-2 in human tongue carcinoma and its precursor lesions. Virchows Arch. 2002, 440:594-597.
    • (2002) Virchows Arch. , vol.440 , pp. 594-597
    • Renkonen, J.1    Wolff, H.2    Paavonen, T.3
  • 39
    • 2942621863 scopus 로고    scopus 로고
    • Advances in chemoprevention of head and neck cancer
    • Rhee J.C., Khuri F.R., Shin D.M. Advances in chemoprevention of head and neck cancer. Oncologist 2004, 9:302-311.
    • (2004) Oncologist , vol.9 , pp. 302-311
    • Rhee, J.C.1    Khuri, F.R.2    Shin, D.M.3
  • 40
    • 77956434510 scopus 로고    scopus 로고
    • Roche Applied Science [database on the Internet] [cited December 20, 2005]. Assay Design Center/ProbeFinder. Homo sapiens (Human). Available from .
    • Roche Applied Science [database on the Internet] [cited December 20, 2005]. Assay Design Center/ProbeFinder. Homo sapiens (Human). Available from http://www.universalprobelibrary.com.
  • 41
    • 77956427137 scopus 로고    scopus 로고
    • Roche Applied Science [database on the Internet] [cited December 20, 2005]. Universal ProbeLibrary. Universal ProbeLibrary interest site. Assay Design Center/ProbeFInder. Homo sapiens (Human). Available from
    • Roche Applied Science [database on the Internet] [cited December 20, 2005]. Universal ProbeLibrary. Universal ProbeLibrary interest site. Assay Design Center/ProbeFInder. Homo sapiens (Human). Available from http://www.roche-applied-science.com.
  • 42
    • 8444238986 scopus 로고    scopus 로고
    • Elevated expression of cyclooxygenase-2 in adenocarcinoma of the parotid gland: insights into malignant transformation of pleomorphic adenoma
    • Sakamoto T., Kondo K., Yamasoba T., et al. Elevated expression of cyclooxygenase-2 in adenocarcinoma of the parotid gland: insights into malignant transformation of pleomorphic adenoma. Ann. Otol. Rhinol. Laryngol. 2004, 113:930-935.
    • (2004) Ann. Otol. Rhinol. Laryngol. , vol.113 , pp. 930-935
    • Sakamoto, T.1    Kondo, K.2    Yamasoba, T.3
  • 44
    • 33750884111 scopus 로고    scopus 로고
    • NF-kB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins
    • Santhi W.S., Sebastian P., Varghese B.T., et al. NF-kB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins. Exp. Mol. Pathol. 2006, 81:123-130.
    • (2006) Exp. Mol. Pathol. , vol.81 , pp. 123-130
    • Santhi, W.S.1    Sebastian, P.2    Varghese, B.T.3
  • 47
    • 0028292482 scopus 로고
    • Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis
    • Shin D.M., Ro J.Y., Hong W.K., et al. Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res. 1994, 54:3153-3159.
    • (1994) Cancer Res. , vol.54 , pp. 3153-3159
    • Shin, D.M.1    Ro, J.Y.2    Hong, W.K.3
  • 48
    • 0025774584 scopus 로고
    • Immunohistochemical localization of epidermal growth factor (EGF) and EGF receptor in human oral mucosa and its malignancy
    • Shirasuna K., Hayaskido Y., Sugiyama M., et al. Immunohistochemical localization of epidermal growth factor (EGF) and EGF receptor in human oral mucosa and its malignancy. Virchows Arch. A Pathol. Anat. Histopathol. 1991, 418:349-353.
    • (1991) Virchows Arch. A Pathol. Anat. Histopathol. , vol.418 , pp. 349-353
    • Shirasuna, K.1    Hayaskido, Y.2    Sugiyama, M.3
  • 49
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • Slaughter D.L., Southwick H.W., Smejal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953, 6:963-968.
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.L.1    Southwick, H.W.2    Smejal, W.3
  • 50
    • 0035205190 scopus 로고    scopus 로고
    • Evaluation of TGF-alpha and EGFR expression in oral leukoplakia and oral submucous fibrosis by quantitative immunohistochemistry
    • Srinivasan M., Jewell S.D. Evaluation of TGF-alpha and EGFR expression in oral leukoplakia and oral submucous fibrosis by quantitative immunohistochemistry. Oncology 2001, 61:284-292.
    • (2001) Oncology , vol.61 , pp. 284-292
    • Srinivasan, M.1    Jewell, S.D.2
  • 52
    • 18644365247 scopus 로고    scopus 로고
    • The evolution of predictive oncology and molecular-based therapy for oral cancer prevention
    • Sudbo J., Reith A. The evolution of predictive oncology and molecular-based therapy for oral cancer prevention. Int. J. Cancer 2005, 115:339-345.
    • (2005) Int. J. Cancer , vol.115 , pp. 339-345
    • Sudbo, J.1    Reith, A.2
  • 53
    • 0032483712 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis
    • Taketo M.M. Cyclooxygenase-2 inhibitors in tumorigenesis. J. Natl Cancer Inst. 1998, 90:1609-1620.
    • (1998) J. Natl Cancer Inst. , vol.90 , pp. 1609-1620
    • Taketo, M.M.1
  • 54
    • 1242338040 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma
    • Terakado N., Shintani S., Yano J., et al. Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma. Oral Oncol. 2004, 40:383-389.
    • (2004) Oral Oncol. , vol.40 , pp. 383-389
    • Terakado, N.1    Shintani, S.2    Yano, J.3
  • 55
    • 10744233965 scopus 로고    scopus 로고
    • The mRNA profile of genes in betel quid chewing oral cancer patients
    • Tsai W.C., Tsai S.T., Ko J.Y., et al. The mRNA profile of genes in betel quid chewing oral cancer patients. Oral Oncol. 2004, 40:418-426.
    • (2004) Oral Oncol. , vol.40 , pp. 418-426
    • Tsai, W.C.1    Tsai, S.T.2    Ko, J.Y.3
  • 56
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase-2
    • Tsujii M., DuBois R.N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase-2. Cell 1995, 83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 57
    • 0036177671 scopus 로고    scopus 로고
    • Cyclooxygenase-2: a therapeutic target
    • Turini M.E., Dubois R.N. Cyclooxygenase-2: a therapeutic target. Ann Mev. Med. 2002, 53:35-57.
    • (2002) Ann Mev. Med. , vol.53 , pp. 35-57
    • Turini, M.E.1    Dubois, R.N.2
  • 58
    • 0033552909 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 pathway by HER2 receptor
    • Vadlamudi R., Mandal M., Adam I., et al. Regulation of cyclooxygenase-2 pathway by HER2 receptor. Oncogene 1999, 18:305-314.
    • (1999) Oncogene , vol.18 , pp. 305-314
    • Vadlamudi, R.1    Mandal, M.2    Adam, I.3
  • 59
    • 33747033890 scopus 로고    scopus 로고
    • P53 expression in leukoplakia and carcinoma of the tongue
    • Vora H.H., Trivedi T.I., Shukla S.N., et al. p53 expression in leukoplakia and carcinoma of the tongue. Int. J. Biol. Markers 2006, 21:74-80.
    • (2006) Int. J. Biol. Markers , vol.21 , pp. 74-80
    • Vora, H.H.1    Trivedi, T.I.2    Shukla, S.N.3
  • 60
    • 0035142384 scopus 로고    scopus 로고
    • Carcinogen substrate specificity of human COX-1 and COX-2
    • Wiese F.W., Thompson P.A., Kadlubar F.F. Carcinogen substrate specificity of human COX-1 and COX-2. Carcinogenesis 2001, 21:5-10.
    • (2001) Carcinogenesis , vol.21 , pp. 5-10
    • Wiese, F.W.1    Thompson, P.A.2    Kadlubar, F.F.3
  • 61
    • 0034089566 scopus 로고    scopus 로고
    • Host cyclooxygenase-2 modulates carcinoma growth
    • Williams C.S., Tsujii M., Reese J., et al. Host cyclooxygenase-2 modulates carcinoma growth. J. Clin. Invest. 2000, 105:1598-1594.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1598-1594
    • Williams, C.S.1    Tsujii, M.2    Reese, J.3
  • 62
    • 0028785005 scopus 로고
    • V-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor
    • Xie W., Herchman H.R. v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor. J. Biol. Chem. 1995, 270:27622-27628.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27622-27628
    • Xie, W.1    Herchman, H.R.2
  • 63
    • 2942552473 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein
    • Ye F., Wu J., Dunn T., et al. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. Cancer Lett. 2004, 211:39-46.
    • (2004) Cancer Lett. , vol.211 , pp. 39-46
    • Ye, F.1    Wu, J.2    Dunn, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.