Gadolinium-conjugated FA-PEG-PAMAM-COOH nanoparticles as potential tumor-targeted circulation-prolonged macromolecular MRI contrast agents

Journal of Applied Polymer Science

Volumn 118, Issue 3, 2010, Pages 1805-1814

  Zhang, Wei Lu ^a,b   Li, Na ^a   Huang, Jin ^a   Yu, Jia Hui ^a   Wang, Da Xin ^c   Li, Ya Ping ^d   Liu, Shi Yuan ^e  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b WENZHOU UNIVERSITY   (China)

^c YANGZHOU UNIVERSITY   (China)

^d SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^e SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cytotoxicity; FA PEG PAMAM Gd nanoparticles; MRI contrast agents; Relaxivity

Indexed keywords

CARBOXYLIC GROUP; COMPLEX REACTIONS; CONTRAST AGENT; ELECTROSPRAY IONIZATION MASS SPECTRA; FOURIER TRANSFORM INFRARED; GD NANOPARTICLE; HUMAN TUMOR CELLS; INDUCTIVELY COUPLED PLASMA ATOMIC EMISSION SPECTROMETER; MAGNETIC RESONANCE IMAGING CONTRAST AGENTS; MASS PERCENTAGE; MRI CONTRAST AGENTS; NANO-SIZED; PASSIVE TARGETING; POLYAMIDOAMINE DENDRIMERS; POLYMER-METAL COMPLEXES; RELAXATION RATES; RELAXIVITY; TUMOR TISSUES;

ATOMIC EMISSION SPECTROSCOPY; CELL MEMBRANES; CYTOTOXICITY; DENDRIMERS; ELECTROMAGNETIC INDUCTION; ELECTROSPRAY IONIZATION; FOURIER TRANSFORMS; INDUCTIVELY COUPLED PLASMA; MACROMOLECULES; MAGNETIC RESONANCE IMAGING; MASS SPECTROMETRY; METAL COMPLEXES; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE; RESONANCE; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

GADOLINIUM;

EID: 77956427910     PISSN: 00218995     EISSN: 10974628     Source Type: Journal    
DOI: 10.1002/app.32494     Document Type: Article

References (29)

1. Bogdanov, A. A. Jr.; Weissleder, R. Trends Biotech 2002, 20, 511.
2. Ye, F. R.; Ke, T. Y.; Jeong, E. K.; Wang, X. L.; Sun, Y. E.; Johnson, M.; Lu, Z. R. Mol Pharm 2006, 3, 507.
3. Schroeder, T. Nature 2008, 453, 345.
4. Herschman, H. R. Science 2003, 302, 605.
5. Weissleder, R.; Mahmood, U. Radiology 2001, 219, 316.
6. Wilhelm, C.; Gazeau, F. Biomaterials 2008, 29, 3161.
7. Caravan, P. Chem Soc Rev 35, 512
8. Kim, J. H.; Park, K.; Nam, H. Y.; Lee, S.; Kim, K.; Kwon, I. C. Prog Polym Sci 2007, 32, 1031.
9. Doble, D. M. J.; Botta, M.; Wang, J.; Aime, S.; Barge, A.; Raymond, K. N. J Am Chem Soc 2001, 123, 10758.
10. Arebizak, R.; Schaefer, M.; Dellacherie, E. Bioconjugate Chem 1997, 8, 605.
11. Weissleder, R.; Bogdanov, A.; Tung, C. H.; Weinmann, H. J. Bioconjugate Chem 2001, 12, 213.
12. Wang, Y.; Ye, F.; Jeong, E. K.; Sun, Y.; Parker, D. L.; Lu, Z. R. Pharm Res 2007, 24, 1208.
13. Shu, J.; Li, J. Q.; Xu, M.; Luo, S. F.; Liu, S. Y.; Yu, J. H.; Cong, R.; Du, B. Acta Polym Sinica 2008, 2, 116.
14. Mohs, A. M.; Wang, X.; Goodrich, K. C.; Zong, Y.; Parker, D. L.; Lu, Z. R. Bioconjugate Chem 2004, 15, 1424.
15. Venditto, V. J.; Aida, C.; Brechbiel, M. W. Mol Pharmacol 2005, 2, 302.
16. Langereis, S.; De Lussanet, Q. G.; Van Genderen, M. H. P.; Backes, W. H.; Meijer, E. W. Macromolecules 2004, 37, 3084.
17. Kobayashi, H.; Sato, N.; Saga, T.; Nakamoto, Y.; Ishimori, T.; Toyama, S.; Togashi, K.; Konishi, J.; Brechbiel, M. W. Eur J Nucl Med 2000, 27, 1334.
18. Konda, S. D.; Aref, M.; Wang, S.; Brechbiel, M.; Wiener, E. C. Magn Reson Mater Phys Biol Med 2001, 12, 104.
19. Weitman, S. D.; Lark, R. H.; Coney, L. R.; Fort, D. W.; Frasca, V.; Zurawski, V. R. J.; Kamen, B. A. Can Res 1992, 52, 3396.
20. Ross, J. F.; Chaudhuri, P. K.; Ratnam, M. Cancer 1994, 73, 2432.
21. Fahmy, T. M.; Fong, P. M.; Goyal, A.; Saltzman, W. M. Nanotoday 2005, 8, 18.
22. Desser, T. S.; Rubin, D. L.; Muller, H. H.; Qing, F.; Khodor, S.; Zanazzi, G.; Young, S. U.; Ladd, D. L.; Wellons, J. A.; Kellar, K. E.; Toner, J. L.; Snow, R. A. J Magn Reson Imaging 1994, 4, 467.
23. Kono, K.; Kojima, C.; Hayashi, N.; Nishisaka, E.; Kiura, K.; Watarai, S.; Harada, A. Biomaterials 2008, 29, 1664.
24. Kim, Y.; Klutz, A. M.; Jacobson, K. A. Bioconjugate Chem 2008, 19, 1660.
25. Agrawal, P.; Gupta, U.; Jain, N. K. Biomaterials 2007, 28, 3349.
26. Jevprasesphant, R.; Penny, J.; Jalal, R.; Attwood, D.; Mckeown, N. B.; D'emanuele, A. Int J Pharm 2003, 252, 263.
27. Hirsch, L. R.; Gobin, A. M.; Lowery, A. R.; Tam, F.; Drezek, R. A.; Halas, N. J.; West, J. L. Ann Biomed Eng 2006, 34, 15.
28. Won, J.; Kim, M.; Yi, Y. W.; Kim, Y. H.; Jung, N.; Kim, T. K. Science 2005, 309, 121.
29. Ezra, A.; Golomb, G. Adv Drug Deliv Rev 2000, 42, 175.