The effects of a novel adjuvant complex/Eimeria profilin vaccine on the intestinal host immune response against live E. acervulina challenge infection

Vaccine

Volumn 28, Issue 39, 2010, Pages 6498-6504

  Lee, Sung Hyen ^a   Lillehoj, Hyun S ^a   Jang, Seung I ^a   Lee, Kyung Woo ^a   Yancey, Robert J ^b   Dominowski, Paul ^b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b PFIZER INC   (United States)

Author keywords

Adjuvant; Chicken; Coccidiosis; Cytokine; Eimeria profilin; Immunity

Indexed keywords

CARBOMER; CHOLESTEROL; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 17F; INTERLEUKIN 1BETA; ISOTONIC SOLUTION; PROFILIN; PROFILIN ANTIBODY; PROTEIN ANTIBODY; PROTOZOAL VACCINE; QUIL A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BROILER; CHICKEN; COCCIDIOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EIMERIA; EIMERIA ACERVULINA; EMULSION; FECES ANALYSIS; GENETIC TRANSCRIPTION; IMMUNIZATION; INTESTINE INJURY; LYMPHOCYTE PROLIFERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYST; PARASITE IMMUNITY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SCORING SYSTEM; WEIGHT GAIN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; BODY WEIGHT; CELL PROLIFERATION; CHICKENS; COCCIDIOSIS; CYTOKINES; EIMERIA; FECES; INTESTINES; LYMPHOCYTES; POULTRY DISEASES; PROFILINS; PROTOZOAN VACCINES; RECOMBINANT PROTEINS;

EID: 77956420542     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.06.116     Document Type: Article

References (68)

1. Lillehoj H.S., Lillehoj E.P. Avian coccidiosis. A review of acquired intestinal immunity and vaccination strategies. Avian Dis 2000, 44:408-425.
2. Williams R.B. Anticoccidial vaccines for broiler chickens: pathways to success. Avian Pathol 2002, 31:317-353.
3. Pogonka T., Klotz C., Kovacs F., Lucius R. A single dose of recombinant Salmonella typhimurium induces specific humoral immune responses against heterologous Eimeria tenella antigens in chicken. Int J Parasitol 2003, 33:81-88.
4. Williams R.B., Carlyle W.W., Bond D.R., Brown I.A. The efficacy and economic benefits of Paracox, a live attenuated anticoccidial vaccine, in commercial trials with standard broiler chickens in the United Kingdom. Int J Parasitol 1999, 29:341-355.
5. Williams R.B., Catchpole J. A new protocol for a challenge test to assess the efficacy of live anticoccidial vaccines for chickens. Vaccine 2000, 18:1178-1185.
6. Song K.D., Lillehoj H.S., Choi K.D., Yun C.H., Parcells M.S., Huynh J.T., et al. A DNA vaccine encoding a conserved Eimeria protein induces protective immunity against live Eimeria acervulina challenge. Vaccine 2000, 19:243-252.
7. Min W., Lillehoj H.S., Burnside J., Weining K.C., Staeheli P., Zhu J.J. Adjuvant effects of IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ, TGF-β4 and lymphotactin on DNA vaccination against Eimeria acervulina. Vaccine 2001, 20:267-274.
8. Ding X., Lillehoj H.S., Dalloul R.A., Min W., Sato T., Yasuda A., et al. In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis. Vaccine 2005, 23:3733-3740.
9. Du A., Wang S. Efficacy of a DNA vaccine delivered in attenuated Salmonella typhimurium against Eimeria tenella infection in chickens. Int J Parasitol 2005, 35:777-785.
10. Yarovinsky F., Zhang D., Andersen J.F., Bannenberg G.L., Serhan C.N., Hayden M.S., et al. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 2005, 308:1626-1629.
11. Plattner F., Yarovinsky F., Romero S., Didry D., Carlier M.F., Sher A., et al. Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response. Cell Host Microbe 2008, 3:61-63.
12. Danforth H.D., Augustine P.A. Eimeria tenella: use of monoclonal antibody in determining the intracellular fate of the refractile body organelles and the effect on in vitro development. Exp Parasitol 1989, 68:1-7.
13. + T cell response. Immunity 2006, 25:525-527.
14. Lillehoj H.S., Choi K.D., Jenkins M.C., Vakharia V.N., Song K.D., Han J.Y., et al. A recombinant Eimeria protein inducing interferon-gamma production: comparison of different gene expression systems and immunization strategies for vaccination against coccidiosis. Avian Dis 2000, 44:379-389.
15. Baldridge J.R., Ward J.R. Effective adjuvants for the induction of antigen-specific delayed-type hypersensitivity. Vaccine 1997, 15:395-401.
16. Gupta R.K., Siber G.R. Adjuvants for human vaccines-current status, problems and future prospects. Vaccine 1995, 13:1263-1276.
17. Richards R.L., Alving C.R., Wassef N.M. Liposomal subunit vaccines: effects of lipid A and aluminum hydroxide on immunogenicity. J Pharm Sci 1996, 85:1286-1289.
18. Lacaille-Dubois M., Wagner H. A review of the biological and pharmacological activities of saponins. Phytomedicine 1996, 2:363-386.
19. Ozel M., Hoglund S., Gelderblom H.R., Morein B. Quaternary structure of the immunostimulating complex (ISCOM). J Ultrastruct Mol Struct Res 1989, 102:240-248.
20. Gall D. The adjuvant activity of aliphatic nitrogenous bases. Immunology 1966, 11:369-386.
21. Korsholm K.S., Agger E.M., Foged C., Christensen D., Dietrich J., Andersen C.S., et al. The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes. Immunology 2007, 121:216-226.
22. Katz D., Inbar I., Samina I., Peleg B.A., Heller D.E. Comparison of dimethyl dioctadecyl ammonium bromide, Freund's complete adjuvant and mineral oil for induction of humoral antibodies, cellular immunity and resistance to Newcastle disease virus in chickens. FEMS Immunol Med Microbiol 1993, 7:303-313.
23. Lillehoj H.S., Lindblad E.B., Nichols M. Adjuvanticity of dimethyl diooctadecyl ammonium bromide, complete Freund's adjuvant and Corynebacterium parvum with respect to host immune response to coccidial antigens. Avian Dis 1993, 37:731-740.
24. Dominowski PJ, Mannan RM, Krebs RL, Thompson JR, Childers TA, Olsen MK, et al. Novel adjuvant compositions. U.S. Patent application number 20,090,324,641 (). http://www.freepatentsonline.com/y2009/0324641.html.
25. Lee S.H., Lillehoj H.S., Park D.W., Jang S.I., Morales A., García D., et al. Induction of passive immunity in broiler chickens against Eimeria acervulina by hyperimmune egg yolk immunoglobulin Y. Poult Sci 2009, 88:562-566.
26. Lee S.H., Lillehoj H.S., Cho S.M., Park D.W., Hong Y.H., Chun H.K., et al. Immunomodulatory properties of dietary plum on coccidiosis. Comp Immunol Microb 2008, 31:389-402.
27. ®) on coccidiosis in broiler chickens. Comp Immunol Microb 2007, 30:261-268.
28. Lee S.H., Lillehoj H.S., Park D.W., Jang S.I., Morales A., García D., et al. Protective effect of hyperimmune egg yolk IgY antibodies against Eimeria tenella and Eimeria maxima infections. Vet Parasitol 2009, 163:123-126.
29. Lee S.H., Lillehoj H.S., Dalloul R.A., Park D.W., Hong Y.H., Lin J.J. Influence of Pediococcus-based probiotic on coccidiosis in broiler chickens. Poult Sci 2007, 86:63-66.
30. Johnson J., Reid W.M. Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens. Exp Parasitol 1970, 28:30-36.
31. Lee S.H., Lillehoj H., Chun H.K., Tuo W., Park H., Cho S.M., et al. In vitro treatment of chicken peripheral blood lymphocytes, macrophages, and tumor cells with extracts of Korean medicinal plants. Nutr Res 2007, 27:362-366.
32. Lee S.H., Lillehoj H.S., Cho S.M., Chun H.K., Park H.J., Lim C.I., et al. Immunostimulatory effects of oriental plum (Prunus salicina Lindl.). Comp Immunol Microb 2009, 32:407-417.
33. Muller P.Y., Janovjak H., Miserez A.R., Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002, 32:1372-1379.
34. Lee S.H., Lillehoj H.S., Jang S.I., Kim D.K., Ionescu C., Bravo D. Effect of dietary curcuma, capsicum, and lentinus on enhancing local immunity against Eimeria acervulina infection. J Poult Sci 2010, 47:89-95.
35. Watts A.M., Kennedy R.C. DNA vaccination strategies against infectious diseases. Int J Parasitol 1999, 29:1149-1163.
36. Livingston P. Ganglioside vaccines with emphasis on CM2. Semin Oncol 1998, 25:638-645.
37. Musselli C., Livingston P.O., Ragupathi G. Keyhole limpet hemocyanin conjugate vaccines against cancer: the Memorial Sloan Kettering experience. J Cancer Res Clin 2001, 127:R20-R26.
38. Waite D.C., Jacobson E.W., Ennis F.A., Edelman R., White B., Kammer R., et al. Three double-blind randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21. Vaccine 2001, 19:3957-3967.
39. Gilewski T., Adluri S., Ragupathi G., Zhang S., Yao T.J., Panageas K., et al. Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21. Clin Cancer Res 2001, 6:1693-1701.
40. Klinguer C., Beck A., De-Lys P., Bussat M.C., Blaecke A., Derouet F., et al. Lipophilic quaternary ammonium salt acts as a mucosal adjuvant when co-administered by the nasal route with vaccine antigens. Vaccine 2001, 19:4236-4244.
41. Katz D, Kraaijeveld CA, Snippe H Synthetic lipoid compounds as antigen-specific immunostimulators for improving the efficacy of killed-virus vaccines. The theory and practical application of adjuvants 1995, 38-50. Wiley, Chichester. D.E.S. Stewart-Tull (Ed.).
42. Hilgers L.A., Snippe H. DDA as an immunological adjuvant. Res Immunol 1992, 143:494-503.
43. Lindblad E.B., Elhay M.J., Silva R., Appelberg R., Andersen P. Adjuvant modulation of immune responses to tuberculosis subunit vaccines. Infect Immun 1997, 65:623-629.
44. Veronesi R., Correa A., Alterio D. Single dose immunisation against tetanus promising results in human trials. Rev Inst Med Trop Sao Paulo 1970, 12:46-54.
45. Stanfield J.P., Gall D., Bracken P.M. Single-dose antenatal tetanus immunisation. Lancet 1973, 1:215-219.
46. Chambers J.D., Thomas C.R., Hobbs J.R. Induction of specific transplantation tolerance in man by autoblast immunisation. Blut 1980, 41:229-236.
47. Minke J.M., Audonnet J.C., Jessett D.M., Fischer L., Guigal P.M., Coupier H., et al. Canarypox as a vector for influenza and EHV-1 genes: challenges and rewards. Proceedings of the second international veterinary vaccines and diagnostic conference, Oxford 2000, 36.
48. Minke J.M., Fischer L., Baudu P., Guigal P.M., Sindle T., Mumford J.A., et al. Use of DNA and recombinant canarypox viral (ALVAC) vectors for equine herpes virus vaccination. Vet Immunol Immunopathol 2006, 111:47-57.
49. Lillehoj H.S., Okamura M. Host immunity and vaccine development to coccidia and Salmonella infections in chickens. J Poult Sci 2003, 40:151-193.
50. Hong Y.H., Lillehoj H.S., Lillehoj E.P., Lee S.H. Changes in immune-related gene expression and intestinal lymphocyte subpopulations following Eimeria maxima infection of chickens. Vet Immunol Immunopathol 2006, 114:259-272.
51. Lee S.H., Lillehoj H.S., Cho S.M., Park D.W., Hong Y.H., Lillehoj E.P., et al. Protective effects of dietary safflower (Carthamus tinctorius) on experimental coccidiosis. J Poult Sci 2008, 46:155-162.
52. Hong Y.H., Lillehoj H.S., Lee S.H., Dalloul R.A., Lillehoj E.P. Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections. Vet Immunol Immunopathol 2006, 114:209-223.
53. Lillehoj H.S., Min W., Choi K.D., Babu U.S., Burnside J., Miyamoto T., et al. Molecular, cellular, and functional characterization of chicken cytokines homologous to mammalian IL-15 and IL-2. Vet Immunol Immunopathol 2001, 82:229-244.
54. Lillehoj H.S., Kim C.H., Keeler C.L., Zhang S. Immunogenomic approaches to study host immunity to enteric pathogens. Poult Sci 2007, 86:1491-1500.
55. Jang SI, Lillehoj HS, Lee SH, Lee KW, Park MS, Bauchan GR, et al. Immunoenhancing effects of MontanideTM ISA oil-based adjuvants on recombinant coccidia antigen vaccination against Eimeria acervulina infection. Vet Parasitol in press.
56. Yao Z., Painter S.L., Fanslow W.C., Ulrich D., Macduff B.M., Spriggs M.K., et al. Human IL-17: a novel cytokine derived from T cells. J Immunol 1995, 155:5483-5486.
57. Yao Z., Fanslow W.C., Seldin M.F., Rousseau A.M., Painter S.L., Comeau M.R., et al. Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 1995, 3:811-821.
58. Broxmeyer H.E. Is interleukin 17, an inducible cytokine that stimulates production of other cytokines, merely a redundant player in a sea of other biomolecules?. J Exp Med 1996, 183:2411-2415.
59. Fossiez F., Djossou O., Chomarat P., Flores-Romo L., Ait-Yahia S., Maat C., et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 1996, 183:2593-2603.
60. Hong Y.H., Lillehoj H.S., Park D.W., Lee S.H., Han J.Y., Shin J.H., et al. Cloning and functional characterization of chicken interleukin-17D. Vet Immunol Immunopathol 2008, 126:1-8.
61. Min W., Lillehoj H.S. Isolation and characterization of chicken interleukin-17 cDNA. J Interferon Cytokine Res 2002, 22:1123-1128.
62. Lillehoj H.S., Ding X., Quiroz M.A., Bevensee E., Lillehoj E.P. Resistance to intestinal Coccidiosis following DNA immunization with the cloned 3-1Eimeria gene plus IL-2, IL-15, and IFN-c. Avian Dis 2005, 49:112-117.
63. Lillehoj H.S., Min W.G., Dalloul R.A. Recent progress on the cytokine regulation of intestinal immune response to Eimeria. Poult Sci 2004, 83:611-623.
64. Lillehoj H.S., Choi K.D. Recombinant chicken interferon-gamma-mediated inhibition of Eimeria tenella development in vitro and reduction of oocyst production and body weight loss following Eimeria acervulina challenge infection. Avian Dis 1998, 42:307-314.
65. Rothwell L., Young J.R., Zoorob R., Whittaker C.A., Hesketh P., Archer A., et al. Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima. J Immunol 2004, 173:2675-2682.
66. Malefyt W., Haanen J., Spits H., Roncarolo M.G., Velde A., Figdor C., et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991, 174:915-924.
67. Groux H., Powrie F. Regulatory T cells and inflammatory bowel disease. Immunol Today 1999, 20:442-445.
68. Choi K.D., Lillehoj H.S., Song K.D., Han J.Y. Molecular and functional characterization of chicken IL-15. Dev Comp Immunol 1999, 23:165-177.