Exposure to di(n-butyl)phthalate and benzo(a)pyrene alters IL-1β secretion and subset expression of testicular macrophages, resulting in decreased testosterone production in rats

Toxicology and Applied Pharmacology

Volumn 248, Issue 1, 2010, Pages 28-37

  Zheng, Shan Jun ^a,b,c   Tian, Huai Jun ^a,b,c   Cao, Jia ^a   Gao, Yu Qi ^a,b,c  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c The 95478 Unit   (China)

Author keywords

Benzo(a)pyrene; Co exposure; Di(n butyl)phthalate; IL 1 ; Testicular macrophages; Testosterone

Indexed keywords

BENZO[A]PYRENE; INTERLEUKIN 1BETA; PHTHALIC ACID DIBUTYL ESTER; TESTOSTERONE; ENDOCRINE DISRUPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOREGULATION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; TESTOSTERONE SYNTHESIS; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; DRUG INTERACTION; METABOLISM; SECRETION (PROCESS); SPRAGUE DAWLEY RAT; TESTIS; TOXICITY;

RATTUS;

ANIMALS; BENZO(A)PYRENE; DIBUTYL PHTHALATE; DRUG INTERACTIONS; ENDOCRINE DISRUPTORS; INTERLEUKIN-1BETA; MACROPHAGES; MALE; RATS; RATS, SPRAGUE-DAWLEY; TESTIS; TESTOSTERONE;

EID: 77956412063     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.07.008     Document Type: Article

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