The role of Fas/FasL system in the male reproductive toxicity of di-n-butyl phthalate in rats

Fudan University Journal of Medical Sciences

Volumn 33, Issue 6, 2006, Pages 749-752

  Zhang, Yun Hui ^a   Zeng, Yu ^b   Lin, Ling ^a   Chen, Bing Heng ^a   Ao, Hong ^a  

^a FUDAN UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Di n butyl phthalate; Fas FasL; Reproductive toxicity

Indexed keywords

EID: 34249977694     PISSN: 16728467     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. WHO/IPCS. Environmental Health Criteria 189, Di-n-butyl phthalate[R]. Geneva: World Health Organization, 1997
2. ATSDR. Di-n-butyl phthalate[R]. Atlanta: Agency for Toxic Substances and Disease Registry, 2002
3. Kavlock R, Boekelheide K, Chapin R, et al. NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of din-butyl phthalate[J]. Reprod Toxico, 2002, 16(5): 489
4. Foster PM, Mylchreest E, Gaido KW, et al. Effects of phthalate esters on the developing reproductive tract of male rats[J]. Hum Reprod Update, 2001, 7(3): 231
5. Chinese source
6. Chinese source
7. Weller M, Schuster M, Pietsch T, et al. CD95 ligand-induced apoptosis of human medlloblastoma cells [J]. Cancer Letter, 1998, 128; 121
8. Richburg JH, Nanez A, Gao H. Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate [J]. Toxicol Appli Pharmacol, 1999, 160: 271
9. OECD/OCDE. OECD guideline for the testing of chemicals: proposal for updating guideline 414, prenatal developmental toxicity study[R]. Paris: Organisation for Economic Co-operation and Development, 2001
10. Shono T, Kai H, Suita S, et al. Time-specific effects of mono-n-butyl phthalate on the transabdominal descent of the testis in rat fetuses[J]. BJU Int, 2000, 86(1): 121
11. Fukuoka M, Tanimoto T, Zhou Y, et al. Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 1 [J]. J Appl Toxicol, 1989, 9(4): 277
12. Li LH. In vitro culture method[M]//Ding XC, Jiang XZ, Gu ZW. Male Reproductive Toxicology. Beijing: Chinese Population Publishing House, 1997, 78-82
13. Kasahara E, Sato EF, Miyoshi M, et al. Role of oxidative stress in germ cell apoptosis by di (2-thylhexy1) phthalate [J]. Biochem J, 2002, 365(3): 849
14. Li LH, JesterWF, Jr. Orth JM. Effects of relatively low levels of mono-(2-ethylhexy1) phthalate 0n co cultured Sertoli cells and gonocytes from neonatal rats[J]. Toxicol Appli Phammcd, 1998, 153(2): 258