Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-cell responses in mice

Clinical and Vaccine Immunology

Volumn 17, Issue 9, 2010, Pages 1381-1389

  Song, Jae Min ^a   Kim, Yeu Chun ^a,b   Lipatov, Aleksandr S ^c   Pearton, Marc ^d   Davis, C Todd ^c   Yoo, Dae Goon ^a   Park, Kyoung Mi ^a   Chen, Li Mei ^c   Quan, Fu Shi ^a   Birchall, James C ^d   Donis, Ruben O ^c   Prausnitz, Mark R ^b   Compans, Richard W ^a   Kang, Sang Moo ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Georgia Institute of Technology   (United States)

^c NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HEMAGGLUTININ; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INFLUENZA VACCINE; INTERLEUKIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DELIVERY SYSTEM; EPIDERMIS; FEMALE; IMMUNE RESPONSE; IMMUNOGENICITY; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; LANGERHANS CELL; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; VIRUS LIKE AGENT;

ANIMALS; ANTIBODIES, VIRAL; B-LYMPHOCYTES; CYTOKINES; FEMALE; HEMAGGLUTINATION INHIBITION TESTS; HEMAGGLUTININS, VIRAL; HUMANS; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; INJECTIONS, INTRADERMAL; INJECTIONS, INTRAMUSCULAR; LANGERHANS CELLS; MICE; MICE, INBRED BALB C; NEEDLES; SKIN; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TIME FACTORS; VACCINATION; VACCINES, VIROSOME;

EID: 77956410461     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00100-10     Document Type: Article

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