Preparation and evaluation of a novel gastric mucoadhesive sustained-release acyclovir microsphere

Drug Development and Industrial Pharmacy

Volumn 36, Issue 9, 2010, Pages 1098-1105

  Liu, Hongfei ^a   Pan, Weisan ^b   Ke, Peng ^c   Dong, Yixiang ^a   Ji, Lijun ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Acyclovir; Carbopol; In vivo microsphere; Ion exchange resin; Mucoadhesive

Indexed keywords

ACICLOVIR; CARBOPOL 934; GANCICLOVIR; MICROSPHERE;

ANIMAL EXPERIMENT; ARTICLE; COLON; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SCREENING; DRUG SYNTHESIS; DUODENUM; EMULSION; EXPERIMENTAL DOG; GASTROINTESTINAL TRACT; GASTROINTESTINAL TRANSIT; ILEUM; IN VITRO STUDY; IN VIVO STUDY; JEJUNUM; MALE; MAXIMUM PLASMA CONCENTRATION; MUCOADHESION; NONHUMAN; RAT; SINGLE DRUG DOSE; STOMACH; STOMACH MUCOSA; SUSTAINED RELEASE PREPARATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

ABSORPTION; ACYCLOVIR; ADHESIVENESS; ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; DOGS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GASTRIC MUCOSA; INTESTINAL ABSORPTION; MALE; MICROSPHERES; PARTICLE SIZE; RATS; RATS, WISTAR;

EID: 77956404402     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639041003677780     Document Type: Article

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