Development of an aciclovir implant for the effective long-term control of herpes simplex virus type-1 infection in Vero cells and in experimentally infected SKH-1 mice

International Journal of Antimicrobial Agents

Volumn 30, Issue 5, 2007, Pages 428-435

  Johnson, Tory P ^a   Frey, Robin ^a   Modugno, Melissa ^a   Brennan, Timothy P ^a   Margulies, Barry J ^a,b,c  

^a TOWSON UNIVERSITY   (United States)

^b Bioinformatics Program   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aciclovir; Controlled release; Herpes simplex; Murine model; Recrudescence; Silicone; Vero

Indexed keywords

ACICLOVIR; SILICONE; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG IMPLANT; DRUG RELEASE; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IN VIVO STUDY; MOUSE; NONHUMAN; PH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPECTROPHOTOMETRY; STATISTICAL ANALYSIS; TEMPERATURE; ULTRAVIOLET IRRADIATION; VERO CELL; VIRUS DETECTION; VIRUS INHIBITION; VIRUS ISOLATION; VIRUS REACTIVATION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; DELAYED-ACTION PREPARATIONS; DRUG IMPLANTS; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; MICE; VERO CELLS; VIRUS ACTIVATION;

EID: 34848870564     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2007.07.003     Document Type: Article

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