Anthrax spore detection by a luminex assay based on monoclonal antibodies that recognize anthrose-containing oligosaccharides

Clinical and Vaccine Immunology

Volumn 17, Issue 9, 2010, Pages 1446-1451

  Tamborrini, Marco ^a,b   Holzer, Marcelle ^c   Seeberger, Peter H ^d,e   Schürch, Nadia ^c   Pluschke, Gerd ^a,b  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c SPIEZ LABORATORY   (Switzerland)

^d MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^e FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; MONOCLONAL ANTIBODY; OLIGOSACCHARIDE; RHAMNOSE;

ARTICLE; BACILLUS ANTHRACIS; BACTERIAL ENDOSPORE; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; PRIORITY JOURNAL;

AMINO SUGARS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; BACILLUS ANTHRACIS; BACILLUS CEREUS; BACTERIOLOGICAL TECHNIQUES; CROSS REACTIONS; DEOXYGLUCOSE; IMMUNOASSAY; MICROSPHERES; OLIGOSACCHARIDES; SENSITIVITY AND SPECIFICITY; SPORES, BACTERIAL;

EID: 77956401877     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00205-10     Document Type: Article

References (24)

1. Adamo, R., R. Saksena, and P. Kováč. 2005. Synthesis of the anomer of the β spacer-equipped tetrasaccharide side chain of the major glycoprotein of the Bacillus anthracis exosporium. Carbohydr. Res. 340:2579-2582.
2. Andreotti, P. E., G. V. Ludwig, A. H. Peruski, J. J. Tuite, S. S. Morse, and L. F. Peruski, Jr. 2003. Immunoassay of infectious agents. Biotechniques 4:850-859.
3. Berry, J. D. 2005. Rational monoclonal antibody development to emerging pathogens, biothreat agents and agents of foreign animal disease: the antigen scale. Vet. J. 170:193-211.
4. Crich, D., and O. Vinogradova. 2007. Synthesis of the antigenic tetrasaccharide side chain from the major glycoprotein of Bacillus anthracis exosporium. J. Org. Chem. 72:6513-6520.
5. Dang, J. L., K. Heroux, J. Kearney, A. Arasteh, M. Gostomski, and P. A. Emanuel. 2001. Bacillus spore inactivation methods affect detection assays. Appl. Environ. Microbiol. 67:3665-3670.
6. Daubenspeck, J. M., H. Zeng, P. Chen, S. Dong, C. T. Steichen, N. R. Krishna, D. G. Pritchard, and C. L. Turnbough, Jr. 2004. Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium. J. Biol. Chem. 279:30945-30953.
7. Dong, S., S. A. McPherson, L. Tan, O. N. Chesnokova, C. L. Turnbough, Jr., and D. G. Pritchard. 2008. Anthrose biosynthetic operon of Bacillus anthracis. J. Bacteriol. 190:2350-2359.
8. Gerhardt, P. 1967. Cytology of Bacillus anthracis. Fed. Proc. 5:1504-1517.
9. Guo, H., and G. A. O'Doherty. 2007. De novo asymmetric synthesis of the anthrax tetrasaccharide by a palladium-catalyzed glycosylation reaction. Angew. Chem. Int. Ed. Engl. 46:5206-5208.
10. Helgason, E., O. A. Okstad, D. A. Caugant, H. A. Johansen, A. Fouet, M. Mock, I. Hegna, and A. B. Kolstø. 2000. Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis - one species on the basis of genetic evidence. Appl. Environ. Microbiol. 66:2627-2630.
11. Hoile, R., M. Yuen, G. James, and G. L. Gilbert. 2007. Evaluation of the rapid analyte measurement platform (RAMP) for the detection of Bacillus anthracis at a crime scene. Forensic Sci. Int. 171:1-4.
12. King, D., V. Luna, A. Cannons, J. Cattani, and P. Amuso. 2003. Performance assessment of three commercial assays for direct detection of Bacillus anthracis spores. J. Clin. Microbiol. 41:3454-3455.
13. Kubler-Kielb, J., E. Vinogradov, H. Hu, S. H. Leppla, J. B. Robbins, and R. Schneerson. 2008. Saccharides cross-reactive with Bacillus anthracis spore glycoprotein as an anthrax vaccine component. Proc. Natl. Acad. Sci. U. S. A. 105:8709-8712.
14. Kuehn, A., P. Kovác, R. Saksena, N. Bannert, S. R. Klee, H. Ranisch, and R. Grunow. 2009. Development of antibodies against anthrose tetrasaccharide for specific detection of Bacillus anthracis spores. Clin. Vaccine Immunol. 16:1728-1737.
15. Mehta, A. S., E. Saile, W. Zhong, T. Buskas, R. Carlson, E. Kannenberg, Y. Reed, C. P. Quinn, and G. J. Boons. 2006. Synthesis and antigenic analysis of the BclA glycoprotein oligosaccharide from the Bacillus anthracis exosporium. Chemistry 12:9136-9149.
16. Pluschke, G., A. Joss, J. Marfurt, C. Daubenberger, O. Kashala, M. Zwickl, A. Stief, G. Sansig, B. Schlapfer, S. Linkert, H. van der Putten, N. Hardman, and M. Schroder. 1998. Generation of chimeric monoclonal antibodies from mice that carry human immunoglobulin Cgamma1 heavy of Ckappa light chain gene segments. J. Immunol. Methods 215:27-37.
17. Saksena, R., R. Adamo, and P. Kováč. 2005. Studies toward a conjugate vaccine for anthrax. Synthesis and characterization of anthrose [4,6-dideoxy- 4-(3-hydroxy-3-methylbutanamido)-2-O-methyl-D-glucopyranose] and its methyl glycosides. Carbohydr. Res. 340:1591-1600.
18. Saksena, R., R. Adamo, and P. Kováč. 2006. Synthesis of the tetrasaccharide side chain of the major glycoprotein of the Bacillus anthracis exosporium. Bioorg. Med. Chem. Lett. 16:615-617.
19. Saksena, R., R. Adamo, and P. Kováč. 2007. Immunogens related to the synthetic tetrasaccharide side chain of Bacillus anthracis exosporium. Bioorg. Med. Chem. Lett. 15:4283-4310.
20. Tamborrini, M., M. A. Oberli, D. B. Werz, N. Schürch, J. Frey, P. H. Seeberger, and G. Pluschke. 2009. Immuno-detection of anthrose containing tetrasaccharide in the exosporium of Bacillus anthracis and Bacillus cereus strains. J. Appl. Microbiol. 106:1618-1628.
21. Tamborrini, M., D. B. Werz, J. Frey, G. Pluschke, and P. H. Seeberger. 2006. Anti-carbohydrate antibodies for the detection of anthrax spores. Angew. Chem. Int. Ed. Engl. 45:6581-6582.
22. Werz, D. B., A. Adibekian, and P. H. Seeberger. 2007. Synthesis of a spore surface pentasaccharide of Bacillus anthracis. Eur. J. Org. Chem. 12:1976-1982.
23. Werz, D. B., and P. H. Seeberger. 2005. Total synthesis of antigen Bacillus anthracis tetrasaccharide - creation of an anthrax vaccine candidate. Angew. Chem. Int. Ed. Engl. 44:6315-6318.
24. World Health Organization. 1998. Guidelines for the surveillance and control of anthrax in humans and animals, 3rd ed. World Health Organization, Geneva, Switzerland.