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Volumn 170, Issue 2, 2005, Pages 193-211

Rational monoclonal antibody development to emerging pathogens, biothreat agents and agents of foreign animal disease: The antigen scale

Author keywords

Antigen scale; Bacillus anthracis; FMD virus; HIV 1; Immunogen; Monoclonal antibody; Pathogen; SARS CoV; Vaccine

Indexed keywords

ANTIGEN; DNA VACCINE; MONOCLONAL ANTIBODY; RECOMBINANT ANTIBODY;

EID: 23944444475     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2004.04.021     Document Type: Article
Times cited : (27)

References (111)
  • 2
    • 0027133248 scopus 로고
    • Effect of cationization on anti-hapten antibody responses in sheep and mice
    • K.G. Altmann Effect of cationization on anti-hapten antibody responses in sheep and mice Immunology and Cell Biology 71 1993 517-525
    • (1993) Immunology and Cell Biology , vol.71 , pp. 517-525
    • Altmann, K.G.1
  • 5
    • 2942550031 scopus 로고    scopus 로고
    • Generation of antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences
    • C.F. Barbas D. Burton J. Scott G. Silverman (Eds.), Cold Spring Harbour Laboratory Press Cold Spring Harbour
    • J. Andris-Widhopf P. Steinberger R. Fuller C. Rader C.F. Barbas III Generation of antibody libraries: PCR amplification and assembly of light- and heavy-chain coding sequences In: C.F. Barbas D. Burton J. Scott G. Silverman (Eds.), Phage Display: A Laboratory Manual 2001 Cold Spring Harbour Laboratory Press Cold Spring Harbour 8.1-8.18
    • (2001) Phage Display: A Laboratory Manual
    • Andris-Widhopf, J.1    Steinberger, P.2    Fuller, R.3    Rader, C.4    Barbas III, C.F.5
  • 11
    • 0031823612 scopus 로고    scopus 로고
    • Monoclonal antibodies, against O1 serotype foot-and-mouth disease virus, from a natural bovine host, recognise similar antigenic features to those defined by the mouse
    • P.V. Barnett A.R. Samuel L. Pullen D. Ansell R.N Butcher R.M. Parkhouse Monoclonal antibodies, against O1 serotype foot-and-mouth disease virus, from a natural bovine host, recognise similar antigenic features to those defined by the mouse Journal of General Virology 79 1998 1687-1697
    • (1998) Journal of General Virology , vol.79 , pp. 1687-1697
    • Barnett, P.V.1    Samuel, A.R.2    Pullen, L.3    Ansell, D.4    Butcher, R.N.5    Parkhouse, R.M.6
  • 12
    • 0028408170 scopus 로고
    • Production of monoclonal antibodies by genetic immunisation
    • M.A. Barry M.E. Barry S.A. Johnston Production of monoclonal antibodies by genetic immunisation Biotechniques 16 1994 616-618
    • (1994) Biotechniques , vol.16 , pp. 616-618
    • Barry, M.A.1    Barry, M.E.2    Johnston, S.A.3
  • 13
    • 0023764193 scopus 로고
    • Effect of the elapsed time after the final antigen boost on the specificity of monoclonal antibodies produced by B cell hybridomas
    • R. Bazin R. Lemieux Effect of the elapsed time after the final antigen boost on the specificity of monoclonal antibodies produced by B cell hybridomas Journal of Immunological Methods 112 1988 53-56
    • (1988) Journal of Immunological Methods , vol.112 , pp. 53-56
    • Bazin, R.1    Lemieux, R.2
  • 14
    • 0023821895 scopus 로고
    • The dynamic nature of the antibody repertoire
    • C. Berek C. Milstein The dynamic nature of the antibody repertoire Immunology Reviews 105 1988 6-26
    • (1988) Immunology Reviews , vol.105 , pp. 6-26
    • Berek, C.1    Milstein, C.2
  • 17
    • 33645436893 scopus 로고    scopus 로고
    • The production of monoclonal antibody by hybridoma fusion: Immortalisation of sensitized B lymphocytes from immune mice
    • Massachusetts Institute of technology, Electronic Protocol
    • Berry, J.D., Ranada, F., 2003. The production of monoclonal antibody by hybridoma fusion: Immortalisation of sensitized B lymphocytes from immune mice; Massachusetts Institute of technology, Electronic Protocol http://iprotocol.mit.edu/protocol/335.htm.
    • (2003)
    • Berry, J.D.1    Ranada, F.2
  • 18
    • 1842605532 scopus 로고    scopus 로고
    • Antibody libraries from immune repertoires
    • Sidhu, S. (Ed.) Marcel Dekker, Inc., New York (in press)
    • Berry, J.D., Popkov, M., 2004. Antibody libraries from immune repertoires. In: Sidhu, S. (Ed.), Phage Display in Biotechnology and Drug Discovery. Marcel Dekker, Inc., New York (in press).
    • (2004) Phage Display in Biotechnology and Drug Discovery
    • Berry, J.D.1    Popkov, M.2
  • 20
    • 0034717212 scopus 로고    scopus 로고
    • Functional human monoclonal antibodies of all isotypes constructed from phage display library-derived single-chain Fv antibody fragments
    • E. Boel S. Verlaan M. Poppelier N. Westerdaal J. Van Strijp T. Logtenberg Functional human monoclonal antibodies of all isotypes constructed from phage display library-derived single-chain Fv antibody fragments Journal of Immunological Methods 239 2000 153-166
    • (2000) Journal of Immunological Methods , vol.239 , pp. 153-166
    • Boel, E.1    Verlaan, S.2    Poppelier, M.3    Westerdaal, N.4    Van Strijp, J.5    Logtenberg, T.6
  • 22
    • 0037378503 scopus 로고    scopus 로고
    • Distinct mechanisms of neutralisation by monoclonal antibodies specific for sites in the N-terminal or C-terminal domain of murine leukaemia virus SU
    • M.D. Burkhart S.C. Kayman Y. He A. Pinter Distinct mechanisms of neutralisation by monoclonal antibodies specific for sites in the N-terminal or C-terminal domain of murine leukaemia virus SU Journal of Virology 77 2003 3993-4003
    • (2003) Journal of Virology , vol.77 , pp. 3993-4003
    • Burkhart, M.D.1    Kayman, S.C.2    He, Y.3    Pinter, A.4
  • 23
    • 0028672525 scopus 로고
    • Human antibodies from combinatorial libraries
    • D. Burton C.F. Barbas III Human antibodies from combinatorial libraries Advances in Immunology 57 1994 191-280
    • (1994) Advances in Immunology , vol.57 , pp. 191-280
    • Burton, D.1    Barbas III, C.F.2
  • 24
    • 0031450231 scopus 로고    scopus 로고
    • Neutralisation antigenic sites on type Asia-1 foot-and-mouth disease virus defined by monoclonal antibody-resistant variants
    • G. Butchaiah D.O. Morgan Neutralisation antigenic sites on type Asia-1 foot-and-mouth disease virus defined by monoclonal antibody-resistant variants Virus Research 52 1997 183-194
    • (1997) Virus Research , vol.52 , pp. 183-194
    • Butchaiah, G.1    Morgan, D.O.2
  • 25
    • 0025002969 scopus 로고
    • Influenza virus hemagglutinin specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor
    • A. Caton H. Koprowski Influenza virus hemagglutinin specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor Proceedings of the National Academy of Sciences USA 87 1990 6450-6454
    • (1990) Proceedings of the National Academy of Sciences USA , vol.87 , pp. 6450-6454
    • Caton, A.1    Koprowski, H.2
  • 29
    • 0020035644 scopus 로고
    • A simple, single-step technique for selecting and cloning hybridomas for the production of monoclonal antibodies
    • J.M. Davis J.E. Pennington A.M. Kubler J.F. Conscience A simple, single-step technique for selecting and cloning hybridomas for the production of monoclonal antibodies Journal of Immunological Methods 50 1982 161-171
    • (1982) Journal of Immunological Methods , vol.50 , pp. 161-171
    • Davis, J.M.1    Pennington, J.E.2    Kubler, A.M.3    Conscience, J.F.4
  • 30
    • 0038105517 scopus 로고    scopus 로고
    • Recombinant single-chain variable fragment antibodies directed against Clostridium difficile toxin B produced by use of an optimized phage display system
    • X.K. Deng L.A. Nesbit K.J. Morrow Jr. Recombinant single-chain variable fragment antibodies directed against Clostridium difficile toxin B produced by use of an optimized phage display system Clinical and Diagnostic Laboratory Immunology 10 2003 587-595
    • (2003) Clinical and Diagnostic Laboratory Immunology , vol.10 , pp. 587-595
    • Deng, X.K.1    Nesbit, L.A.2    Morrow Jr., K.J.3
  • 31
    • 0025004285 scopus 로고
    • Random peptide libraries: A source of specific protein binding molecules
    • J.J. Devlin L.C. Panganiban P.E. Devlin Random peptide libraries: A source of specific protein binding molecules Science 249 1990 404-406
    • (1990) Science , vol.249 , pp. 404-406
    • Devlin, J.J.1    Panganiban, L.C.2    Devlin, P.E.3
  • 32
    • 0034425742 scopus 로고    scopus 로고
    • Antibody arrays for high-throughput screening of antibody antigen interactions
    • R. de Wildt C. Mundy B. Gorick I. Tomlinson Antibody arrays for high-throughput screening of antibody antigen interactions Nature Biotechnology 18 2000 989-994
    • (2000) Nature Biotechnology , vol.18 , pp. 989-994
    • de Wildt, R.1    Mundy, C.2    Gorick, B.3    Tomlinson, I.4
  • 33
    • 0028831142 scopus 로고
    • Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure
    • H.J. Ditzel J.M. Binley J.P. Moore J. Sodroski N. Sullivan L.S. Sawyer R.M. Hendry W.P. Yang C.F. Barbas 3rd D.R. Burton Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure J Immunol 154 1995 893-906
    • (1995) J. Immunol. , vol.154 , pp. 893-906
    • Ditzel, H.J.1    Binley, J.M.2    Moore, J.P.3    Sodroski, J.4    Sullivan, N.5    Sawyer, L.S.6    Hendry, R.M.7    Yang, W.P.8    Barbas III, C.F.9    Burton, D.R.10
  • 34
    • 0029922831 scopus 로고    scopus 로고
    • The sheep Ig variable region repertoire consists of a single VH family
    • V. Dufour F. Nau S. Malings The sheep Ig variable region repertoire consists of a single VH family Journal of Immunology 156 1996 2163-2170
    • (1996) Journal of Immunology , vol.156 , pp. 2163-2170
    • Dufour, V.1    Nau, F.2    Malings, S.3
  • 35
    • 0034844030 scopus 로고    scopus 로고
    • Isolation of single-chain antibody fragments against Venezuelan equine encephalomyelitis virus from two different immune sources
    • J.M. Duggan D.M. Coates D. Ulaeto Isolation of single-chain antibody fragments against Venezuelan equine encephalomyelitis virus from two different immune sources Viral Immunology 14 2001 263-273
    • (2001) Viral Immunology , vol.14 , pp. 263-273
    • Duggan, J.M.1    Coates, D.M.2    Ulaeto, D.3
  • 36
    • 33645424791 scopus 로고
    • Potential of primate monoclonal antibodies to substitute for human antibodies: Nucleotide sequences of chimpanzee Fab fragments
    • P.H. Ehrlich K. Harfeldt J. Justice Z. Moustafa L. Ostberg Potential of primate monoclonal antibodies to substitute for human antibodies: nucleotide sequences of chimpanzee Fab fragments Human Antibodies and Hybridomas 6 1990 151-160
    • (1990) Human Antibodies and Hybridomas , vol.6 , pp. 151-160
    • Ehrlich, P.H.1    Harfeldt, K.2    Justice, J.3    Moustafa, Z.4    Ostberg, L.5
  • 39
    • 0023609693 scopus 로고
    • Epitope masking and immunodominance-complications in the selection of monoclonal antibodies against HCG
    • M. Gani J. Coley P. Porter Epitope masking and immunodominance-complications in the selection of monoclonal antibodies against HCG Hybridoma 6 1987 637-643
    • (1987) Hybridoma , vol.6 , pp. 637-643
    • Gani, M.1    Coley, J.2    Porter, P.3
  • 40
    • 0033385018 scopus 로고    scopus 로고
    • Construction of murine phage antibody library and selection of ricin-specific single-chain antibodies
    • X. Gao Y. Huang S. Zhu Construction of murine phage antibody library and selection of ricin-specific single-chain antibodies IUBMB Life 48 1999 513-517
    • (1999) IUBMB Life , vol.48 , pp. 513-517
    • Gao, X.1    Huang, Y.2    Zhu, S.3
  • 42
    • 0033922560 scopus 로고    scopus 로고
    • Antibody Engineering at the millennium
    • J.V. Gavilondo J.W. Larrick Antibody Engineering at the millennium Biotechniques 29 2000 128-149
    • (2000) Biotechniques , vol.29 , pp. 128-149
    • Gavilondo, J.V.1    Larrick, J.W.2
  • 43
  • 44
    • 0026589089 scopus 로고
    • Original and artificial antibodies
    • E. Gherardi C. Milstein Original and artificial antibodies Nature 357 1992 201
    • (1992) Nature , vol.357 , pp. 201
    • Gherardi, E.1    Milstein, C.2
  • 45
    • 0031964765 scopus 로고    scopus 로고
    • Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: Recovery from a long-term-nonprogressor SIV-infected macaque
    • J. Glamann D.R. Burton P.W. Parren H.J. Ditzel K.A. Kent C. Arnold D. Montefiori V.M. Hirsch Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque Journal of Virology 72 1998 585-592
    • (1998) Journal of Virology , vol.72 , pp. 585-592
    • Glamann, J.1    Burton, D.R.2    Parren, P.W.3    Ditzel, H.J.4    Kent, K.A.5    Arnold, C.6    Montefiori, D.7    Hirsch, V.M.8
  • 46
    • 0033941576 scopus 로고    scopus 로고
    • Characterisation of a macaque recombinant monoclonal antibody that binds to a CD4-induced epitope and neutralizes simian immunodeficiency virus
    • J. Glamann J.M.. Hirsch Characterisation of a macaque recombinant monoclonal antibody that binds to a CD4-induced epitope and neutralizes simian immunodeficiency virus Journal of Virology 74 2000 7158-7163
    • (2000) Journal of Virology , vol.74 , pp. 7158-7163
    • Glamann, J.1    Hirsch, J.M.2
  • 47
    • 0022460396 scopus 로고
    • The use of tolerization in the production of monoclonal antibodies against minor antigenic determinants
    • G.S. Golumbeski Jr. R.L. Dimond The use of tolerization in the production of monoclonal antibodies against minor antigenic determinants Analytical Biochemistry 154 1986 373-381
    • (1986) Analytical Biochemistry , vol.154 , pp. 373-381
    • Golumbeski Jr., G.S.1    Dimond, R.L.2
  • 48
    • 0023099127 scopus 로고
    • Production of an ovine monoclonal antibody to testosterone by an interspecies fusion
    • D.J. Groves B.A. Morris K. Tan M. De Silva J. Clayton Production of an ovine monoclonal antibody to testosterone by an interspecies fusion Hybridoma 6 1987 71-76
    • (1987) Hybridoma , vol.6 , pp. 71-76
    • Groves, D.J.1    Morris, B.A.2    Tan, K.3    De Silva, M.4    Clayton, J.5
  • 49
    • 0023408239 scopus 로고
    • Preparation of a bovine monoclonal antibody to testosterone by interspecies fusion
    • D.J. Groves B.A. Morris J. Clayton Preparation of a bovine monoclonal antibody to testosterone by interspecies fusion Research in Veterinary Sciences 43 1987 253-256
    • (1987) Research in Veterinary Sciences , vol.43 , pp. 253-256
    • Groves, D.J.1    Morris, B.A.2    Clayton, J.3
  • 50
    • 0023855236 scopus 로고
    • A bovine monoclonal antibody to oestrone/oestradiol prepared by a (murine×bovine)×bovine interspecies fusion
    • D.J. Groves J. Clayton B.A. Morris A bovine monoclonal antibody to oestrone/oestradiol prepared by a (murine×bovine)× bovine interspecies fusion Veterinary Immunology and Immunopathology 18 1988 95-101
    • (1988) Veterinary Immunology and Immunopathology , vol.18 , pp. 95-101
    • Groves, D.J.1    Clayton, J.2    Morris, B.A.3
  • 51
    • 0033862657 scopus 로고    scopus 로고
    • Veterinary sources of nonrodent monoclonal antibodies: Interspecific and intraspecific hybridomas
    • D.J. Groves B.A. Morris Veterinary sources of nonrodent monoclonal antibodies: Interspecific and intraspecific hybridomas Hybridoma 19 2000 201-214
    • (2000) Hybridoma , vol.19 , pp. 201-214
    • Groves, D.J.1    Morris, B.A.2
  • 52
    • 0022658863 scopus 로고
    • Relationship between three different B cell types and the specific efficiency of hybridoma formation
    • S. Guoliang L. Erxiang W. Anran Relationship between three different B cell types and the specific efficiency of hybridoma formation Scientia Sinica 29 1986 165-172
    • (1986) Scientia Sinica , vol.29 , pp. 165-172
    • Guoliang, S.1    Erxiang, L.2    Anran, W.3
  • 53
    • 0023881174 scopus 로고
    • Antigenic competition in the immune response against protein mixtures: Strain-specific non-immunogenicity of Escherichia coli antigens
    • P. Hammerl R. Weger J. Thalhamer Antigenic competition in the immune response against protein mixtures: Strain-specific non-immunogenicity of Escherichia coli antigens Molecular Immunology 25 1988 313-320
    • (1988) Molecular Immunology , vol.25 , pp. 313-320
    • Hammerl, P.1    Weger, R.2    Thalhamer, J.3
  • 54
    • 0037406621 scopus 로고    scopus 로고
    • Isolation and expression of recombinant antibody fragments to the biological warfare pathogen Brucella melitensis
    • A. Hayhurst S. Happe R. Mabry Z. Koch B.L. Iverson G. Georgiou Isolation and expression of recombinant antibody fragments to the biological warfare pathogen Brucella melitensis Journal of Immunological Methods 276 2003 185-196
    • (2003) Journal of Immunological Methods , vol.276 , pp. 185-196
    • Hayhurst, A.1    Happe, S.2    Mabry, R.3    Koch, Z.4    Iverson, B.L.5    Georgiou, G.6
  • 55
    • 0037341428 scopus 로고    scopus 로고
    • Electron microscopy for rapid diagnosis of infectious agents in emergent situations
    • P.R. Hazelton H.R. Gelderblom Electron microscopy for rapid diagnosis of infectious agents in emergent situations Emerging Infectious Diseases 9 2003 294-303
    • (2003) Emerging Infectious Diseases , vol.9 , pp. 294-303
    • Hazelton, P.R.1    Gelderblom, H.R.2
  • 56
    • 0030974119 scopus 로고    scopus 로고
    • In vitro selection and evolution of functional proteins by using ribosome display
    • J. Hanes A. Pluckthun In vitro selection and evolution of functional proteins by using ribosome display Proceedings of the National Academy of Sciences USA 94 1997 4937-4942
    • (1997) Proceedings of the National Academy of Sciences USA , vol.94 , pp. 4937-4942
    • Hanes, J.1    Pluckthun, A.2
  • 57
    • 0031574037 scopus 로고    scopus 로고
    • Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites
    • M. He M.J. Taussig Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites Nucleic Acids Research 25 1997 5132-5134
    • (1997) Nucleic Acids Research , vol.25 , pp. 5132-5134
    • He, M.1    Taussig, M.J.2
  • 58
    • 0023204052 scopus 로고
    • A MAb to a unique cerebellar neuron generated by immunosuppression and rapid immunisation
    • S. Hockfield A MAb to a unique cerebellar neuron generated by immunosuppression and rapid immunisation Science 237 1987 67-70
    • (1987) Science , vol.237 , pp. 67-70
    • Hockfield, S.1
  • 59
    • 0025740577 scopus 로고
    • Multisubunit proteins on the surface of filamentous phage: Methodologies for displaying antibody Fab heavy and light chains
    • H. Hoogenboom A. Griffiths K. Johnson D. Chiswell P. Hudson G. Winter Multisubunit proteins on the surface of filamentous phage: Methodologies for displaying antibody Fab heavy and light chains Nucleic Acids Research 19 1991 4133-4137
    • (1991) Nucleic Acids Research , vol.19 , pp. 4133-4137
    • Hoogenboom, H.1    Griffiths, A.2    Johnson, K.3    Chiswell, D.4    Hudson, P.5    Winter, G.6
  • 62
    • 0028883531 scopus 로고
    • Production of fully human antibodies by transgenic mice
    • A. Jakobovits Production of fully human antibodies by transgenic mice Current Opinion in Biotechnology 6 1995 561-566
    • (1995) Current Opinion in Biotechnology , vol.6 , pp. 561-566
    • Jakobovits, A.1
  • 63
    • 0037195784 scopus 로고    scopus 로고
    • Enhancement of alpha-helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design
    • J.G. Joyce W.M. Hurni M.J. Bogusky V.M. Garsky X. Liang M.P. Citron R.C. Danzeisen M.D. Miller J.W. Shiver P.M. Keller Enhancement of alpha-helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design J Biol Chem 277 2002 45811-45820
    • (2002) J. Biol. Chem. , vol.277 , pp. 45811-45820
    • Joyce, J.G.1    Hurni, W.M.2    Bogusky, M.J.3    Garsky, V.M.4    Liang, X.5    Citron, M.P.6    Danzeisen, R.C.7    Miller, M.D.8    Shiver, J.W.9    Keller, P.M.10
  • 64
    • 0026753062 scopus 로고
    • Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodies
    • K.A. Kent E. Rud T. Corcoran C. Powell C. Thiriart C. Collignon E.J. Stott Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodies AIDS Research and Human Retroviruses 8 1992 1147-1151
    • (1992) AIDS Research and Human Retroviruses , vol.8 , pp. 1147-1151
    • Kent, K.A.1    Rud, E.2    Corcoran, T.3    Powell, C.4    Thiriart, C.5    Collignon, C.6    Stott, E.J.7
  • 65
    • 0028258055 scopus 로고
    • Isolation of tumor cell-specific single-chain Fv from immunized mice using phage-antibody libraries and the re-construction of whole antibodies from these antibody fragments
    • C.A. Kettleborough K.H. Ansell R. Allen E. Rosell-Vives D. Gussow M. Bendig Isolation of tumor cell-specific single-chain Fv from immunized mice using phage-antibody libraries and the re-construction of whole antibodies from these antibody fragments European Journal of Immunology 24 1994 952-958
    • (1994) European Journal of Immunology , vol.24 , pp. 952-958
    • Kettleborough, C.A.1    Ansell, K.H.2    Allen, R.3    Rosell-Vives, E.4    Gussow, D.5    Bendig, M.6
  • 66
    • 0023716093 scopus 로고
    • Rapid correlation between field isolates and vaccine strains of foot-and-mouth disease virus
    • R.P. Kitching R. Rendle N.P. Ferris Rapid correlation between field isolates and vaccine strains of foot-and-mouth disease virus Vaccine 6 1988 403-408
    • (1988) Vaccine , vol.6 , pp. 403-408
    • Kitching, R.P.1    Rendle, R.2    Ferris, N.P.3
  • 67
    • 0026612981 scopus 로고
    • Mouse variable-region gene families: Complexity, polymorphism and use in non-autoimmune responses
    • R. Kofler S. Geley H. Kofler A. Helmberg Mouse variable-region gene families: Complexity, polymorphism and use in non-autoimmune responses Immunology Reviews 128 1992 5-21
    • (1992) Immunology Reviews , vol.128 , pp. 5-21
    • Kofler, R.1    Geley, S.2    Kofler, H.3    Helmberg, A.4
  • 68
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • G. Kohler C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495-497
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 70
    • 0022597442 scopus 로고
    • A modified method to induce immune polyclonal ascites fluid in BALB/c mice using Sp2/0-Ag14 cells
    • M.J. Lacy E.W. Voss Jr. A modified method to induce immune polyclonal ascites fluid in BALB/c mice using Sp2/0-Ag14 cells Journal of Immunological Methods 87 1986 169-177
    • (1986) Journal of Immunological Methods , vol.87 , pp. 169-177
    • Lacy, M.J.1    Voss Jr., E.W.2
  • 72
    • 0024386188 scopus 로고
    • Polymerase chain reaction using mixed primers: Cloning of human monoclonal antibody variable genes from single hybridomas cells
    • J. Larrick L. Danielson C. Brenner E. Wallace M. Abrahamson K. Fry C.A.K. Borrebaeck Polymerase chain reaction using mixed primers: Cloning of human monoclonal antibody variable genes from single hybridomas cells Biotechnology 7 1989 934-938
    • (1989) Biotechnology , vol.7 , pp. 934-938
    • Larrick, J.1    Danielson, L.2    Brenner, C.3    Wallace, E.4    Abrahamson, M.5    Fry, K.6    Borrebaeck, C.A.K.7
  • 73
    • 0032898068 scopus 로고    scopus 로고
    • Tolerization of adult mice to immunodominant proteins before monoclonal antibody production
    • J.A. LeBron H. Shen P.J. Bjorkman S. Ou Tolerization of adult mice to immunodominant proteins before monoclonal antibody production Journal of Immunological Methods 222 1999 59-63
    • (1999) Journal of Immunological Methods , vol.222 , pp. 59-63
    • LeBron, J.A.1    Shen, H.2    Bjorkman, P.J.3    Ou, S.4
  • 74
    • 0028956970 scopus 로고
    • ...and such are little lymphocytes made of
    • I. Lefkovits ...and such are little lymphocytes made of Research in Immunology 146 1995 5-10
    • (1995) Research in Immunology , vol.146 , pp. 5-10
    • Lefkovits, I.1
  • 76
    • 0025226085 scopus 로고
    • Phage antibodies: Filamentous phage displaying antibody variable domains
    • J. McCafferty A.D. Griffiths G. Winter D.J. Chiswell Phage antibodies: filamentous phage displaying antibody variable domains Nature 348 1990 552-554
    • (1990) Nature , vol.348 , pp. 552-554
    • McCafferty, J.1    Griffiths, A.D.2    Winter, G.3    Chiswell, D.J.4
  • 79
    • 0035851383 scopus 로고    scopus 로고
    • Acute and long-term effects of booster immunisation on frequencies of antigen-specific memory B-lymphocytes
    • R. Nanan D. Heinrich M. Frosch H.W. Kreth Acute and long-term effects of booster immunisation on frequencies of antigen-specific memory B-lymphocytes Vaccine 20 2002 498-504
    • (2002) Vaccine , vol.20 , pp. 498-504
    • Nanan, R.1    Heinrich, D.2    Frosch, M.3    Kreth, H.W.4
  • 82
    • 0030152049 scopus 로고    scopus 로고
    • Characteristics of human antibody repertoires following active immune responses in vivo
    • M. Ohlin C.A.K. Borrebaeck Characteristics of human antibody repertoires following active immune responses in vivo Molecular Immunology 33 1996 583-592
    • (1996) Molecular Immunology , vol.33 , pp. 583-592
    • Ohlin, M.1    Borrebaeck, C.A.K.2
  • 83
    • 33645438347 scopus 로고
    • Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
    • R. Orlandi D. Gussow P. Jones G. Winter Cloning immunoglobulin variable domains for expression by the polymerase chain reaction Biotechnology 192 1989 527-531
    • (1989) Biotechnology , vol.192 , pp. 527-531
    • Orlandi, R.1    Gussow, D.2    Jones, P.3    Winter, G.4
  • 84
    • 0024210147 scopus 로고
    • Antibody-selectable filamentous fd phage vectors: Affinity purification of target genes
    • S.F. Parmley G.P. Smith Antibody-selectable filamentous fd phage vectors: Affinity purification of target genes Gene 73 1988 305-318
    • (1988) Gene , vol.73 , pp. 305-318
    • Parmley, S.F.1    Smith, G.P.2
  • 87
    • 0037225412 scopus 로고    scopus 로고
    • Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: The impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display
    • M. Popkov R.G. Mage C.B. Alexander S. Thundivalappil C.F. Barbas 3rd C. Rader Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: The impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display Journal of Molecular Biology 325 2003 325-335
    • (2003) Journal of Molecular Biology , vol.325 , pp. 325-335
    • Popkov, M.1    Mage, R.G.2    Alexander, C.B.3    Thundivalappil, S.4    Barbas III, C.F.5    Rader, C.6
  • 89
    • 0035135845 scopus 로고    scopus 로고
    • Antibody libraries in drug and target discovery
    • C. Rader Antibody libraries in drug and target discovery Drug Discovery Today 6 2001 36-43
    • (2001) Drug Discovery Today , vol.6 , pp. 36-43
    • Rader, C.1
  • 90
    • 0029043051 scopus 로고
    • Mouse monoclonal antibodies to human immunodeficiency virus glycoprotein 120 generated by repeated immunization with glycoprotein 120 from a single isolate, or by sequential immunization with glycoprotein 120 from three isolates
    • J.P. Reeves C.Y. Lo D.M. Klinman S.L. Epstein Mouse monoclonal antibodies to human immunodeficiency virus glycoprotein 120 generated by repeated immunization with glycoprotein 120 from a single isolate, or by sequential immunization with glycoprotein 120 from three isolates Hybridoma 14 1995 235-242
    • (1995) Hybridoma , vol.14 , pp. 235-242
    • Reeves, J.P.1    Lo, C.Y.2    Klinman, D.M.3    Epstein, S.L.4
  • 91
    • 0034128236 scopus 로고    scopus 로고
    • Identification by phage display and characterisation of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein
    • D.J. Schofield J. Glamann S. Emerson R. Purcell Identification by phage display and characterisation of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein Journal of Virology 74 2000 5548-5555
    • (2000) Journal of Virology , vol.74 , pp. 5548-5555
    • Schofield, D.J.1    Glamann, J.2    Emerson, S.3    Purcell, R.4
  • 92
    • 0036056290 scopus 로고    scopus 로고
    • Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus
    • D.J. Schofield W. Satterfield S.U. Emerson R.H. Purcell Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus Virology 292 2002 127-136
    • (2002) Virology , vol.292 , pp. 127-136
    • Schofield, D.J.1    Satterfield, W.2    Emerson, S.U.3    Purcell, R.H.4
  • 93
    • 0025112794 scopus 로고
    • Searching for peptide ligands with an epitope library
    • J.K. Scott G.P. Smith Searching for peptide ligands with an epitope library Science 249 1990 386-390
    • (1990) Science , vol.249 , pp. 386-390
    • Scott, J.K.1    Smith, G.P.2
  • 94
    • 0029584804 scopus 로고
    • PCR strategies for isolation of the 5′ end of an immunoglobulin-encoding cDNA
    • M.C. Sinclair R. Aitken PCR strategies for isolation of the 5′ end of an immunoglobulin-encoding cDNA Gene 167 1995 285-289
    • (1995) Gene , vol.167 , pp. 285-289
    • Sinclair, M.C.1    Aitken, R.2
  • 95
    • 0031572510 scopus 로고    scopus 로고
    • Bovine IgG repertoire is dominated by a single diversified VH gene family
    • M.C. Sinclair J. Gilchrist R. Aitken Bovine IgG repertoire is dominated by a single diversified VH gene family Journal of Immunology 159 1997 3883-3889
    • (1997) Journal of Immunology , vol.159 , pp. 3883-3889
    • Sinclair, M.C.1    Gilchrist, J.2    Aitken, R.3
  • 96
    • 0021818675 scopus 로고
    • Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
    • G. Smith Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface Science 228 1985 1315-1317
    • (1985) Science , vol.228 , pp. 1315-1317
    • Smith, G.1
  • 97
  • 100
    • 0029919595 scopus 로고    scopus 로고
    • Construction of a combinatorial IgE library from an allergic patient. Isolation and characterisation of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5
    • P. Steinberger D. Kraft R. Valenta Construction of a combinatorial IgE library from an allergic patient. Isolation and characterisation of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5 Journal of Biological Chemistry 271 1996 10967-10972
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 10967-10972
    • Steinberger, P.1    Kraft, D.2    Valenta, R.3
  • 101
    • 0020461749 scopus 로고
    • Dynamics of B cell repertoire formation: Normal patterns of clonal turnover are altered by ligand interaction
    • M.A. Thompson M.P. Cancro Dynamics of B cell repertoire formation: normal patterns of clonal turnover are altered by ligand interaction J Immunol 129 1982 2372-2376
    • (1982) J. Immunol. , vol.129 , pp. 2372-2376
    • Thompson, M.A.1    Cancro, M.P.2
  • 104
    • 0026729144 scopus 로고
    • Subtractive immunisation techniques for the production of monoclonal antibodies to rare antigens
    • C.V. Williams C.L. Stechmann S.C. McLoon Subtractive immunisation techniques for the production of monoclonal antibodies to rare antigens Biotechniques 12 1992 842-847
    • (1992) Biotechniques , vol.12 , pp. 842-847
    • Williams, C.V.1    Stechmann, C.L.2    McLoon, S.C.3
  • 105
    • 0037379220 scopus 로고    scopus 로고
    • Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12
    • S. Wolbank R. Kunert G. Stiegler H. Katinger Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12 Journal of Virology 77 2003 4095-4103
    • (2003) Journal of Virology , vol.77 , pp. 4095-4103
    • Wolbank, S.1    Kunert, R.2    Stiegler, G.3    Katinger, H.4
  • 108
    • 0030732830 scopus 로고    scopus 로고
    • Evaluation of different lymphoid tissue sources for the construction of human immunoglobulin gene libraries
    • Y. Yip N. Hawkins M. Clark R. Ward Evaluation of different lymphoid tissue sources for the construction of human immunoglobulin gene libraries Immunotechnology 3 1997 195-203
    • (1997) Immunotechnology , vol.3 , pp. 195-203
    • Yip, Y.1    Hawkins, N.2    Clark, M.3    Ward, R.4
  • 109
    • 0021352855 scopus 로고
    • Regulation of IgM and IgD synthesis in B lymphocytes. I. Changes in biosynthesis of mRNA for mu and gamma chains
    • D. Yuan P.W. Tucker Regulation of IgM and IgD synthesis in B lymphocytes. I. Changes in biosynthesis of mRNA for mu and gamma chains Journal of Immunology 132 1984 1561-1565
    • (1984) Journal of Immunology , vol.132 , pp. 1561-1565
    • Yuan, D.1    Tucker, P.W.2
  • 111
    • 0028297487 scopus 로고
    • Antibody recognition of a neutralization epitope on the major outer membrane protein of Chlamydia trachomatis
    • G. Zhong J.D. Berry R.C. Brunham Antibody recognition of a neutralization epitope on the major outer membrane protein of Chlamydia trachomatis Infections and Immunology 62 1994 1576-1583
    • (1994) Infections and Immunology , vol.62 , pp. 1576-1583
    • Zhong, G.1    Berry, J.D.2    Brunham, R.C.3


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