Implicit motor learning in patients with Parkinson's and Alzheimer's disease: Differences in learning abilities?

Motor Control

Volumn 14, Issue 3, 2010, Pages 344-361

  Van Tilborg, Ilse A D A ^a,b,c   Hulstijn, Wouter ^c,d  

^a GGZ Dimence   (Netherlands)

^b ELKERLIEK HOSPITAL   (Netherlands)

^c RADBOUD UNIVERSITY   (Netherlands)

^d UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Alzheimer's disease; Implicit learning; Motor skill learning; Parkinson's disease; Sequence learning

Indexed keywords

ADULT; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LEARNING; MALE; MOTOR PERFORMANCE; MOTOR SYSTEM; MOVEMENT (PHYSIOLOGY); PARKINSON DISEASE; REACTION TIME; TASK PERFORMANCE; AGED; APTITUDE; AWARENESS; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; ORIENTATION; PSYCHOLOGY; PSYCHOMOTOR PERFORMANCE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APTITUDE; AWARENESS; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR SKILLS; NEUROPSYCHOLOGICAL TESTS; ORIENTATION; PARKINSON DISEASE; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SERIAL LEARNING;

EID: 77956398927     PISSN: 10871640     EISSN: 15432696     Source Type: Journal    
DOI: 10.1123/mcj.14.3.344     Document Type: Article

References (46)

1. Bapi, R.S., Doya, K., & Harner, A.M. (2000). Evidence for effector independent and dependent representations and their differential time course of acquisition during motor sequence learning. Experimental Brain Research, 132, 149-162.
2. Brown, R.G., & Marsden, C.D. (1990). Cognitive function in Parkinson's disease: from description to theory. Trends in Neurosciences, 13, 21-29. (Pubitemid 20014453)
3. Cohen, A., Ivry, R.I., & Keele, S.W. (1990). Attention and structure in sequence learning. Journal of Experimental Psychology. Learning, Memory, and Cognition, 16(1), 17-30.
4. Cronin-Golomb, A., & Braun, A. E. (1997). Visuospatial dysfunction and problem solving in Parkinson's disease. Neuropsychology, 11, 44-52 (Pubitemid 27086859)
5. Curran, T., & Keele, S.W. (1993). Attentional and nonattentional forms of sequence learning. Journal of Experimental Psychology. Learning, Memory, and Cognition, 19(1), 189-202.
6. De Jong, W.P., Hulstijn, W., Kosterman, B.J.M., & Smits-Engelsman, B.C.M. (1996). OASIS software and its application in experimental handwriting research. In M.L. Simner, C.G. Leedham, & A.J.W.M. Thomassen (Eds.), Handwriting and drawing research: Basic and applied issues (pp. 429-440). Amsterdam: IOS Press.
7. Doyon, J., Gaudreau, D., Laforce, R., Castonguay, M., Bédard, P.J., Bédard, F., et al. (1997). Role of the striatum, cerebellum, and the frontal lobes in the learning of a visuomotor sequence. Brain and Cognition, 34, 218-245. (Pubitemid 27291106)
8. Ferraro, F.R., Balota, D.A., & Connor, L.T. (1993). Implicit memory and the formation of new associations in nondemented Parkinson's disease individuals and individuals with senile dementia of the Alzheimer type: A Serial Reaction Time (SRT) investigation. Brain and Cognition, 21, 163-180.
9. Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). Mini-Mental State: A practical method of grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198.
10. Freeman, R.Q., Giovannetti, T., Lamar, M., Cloud, B.S., Stern, R.A., Kaplan, E., et al. (2000). Visuoconstructional problems in dementia: Contribution of executive system functions. Neuropsychology, 14, 415-426.
11. Grafman, J., Weingartner, H., Newhouse, P.A., Thompson, K., Lalonde, F., Litvan, I., et al. (1990). Implicit learning in patients with Alzheimer's disease. Pharmacopsychiatry, 23, 94-101.
12. Helmuth, L.L., Mayer, U., & Daum, I. (2000). Sequence learning in Parkinson's disease: A comparison of spatial attention and number-response sequences. Neuropsychologia, 38, 1443-1451.
13. Hikosaka, O., Rand, M.K., Miyachi, S., & Miyashita, K. (1995). Learning of sequential movements in the monkey: Process of learning and retention memory. Journal of Neurophysiology, 74(4), 1652-1661.
14. Hikosaka, O., Nakahara, H., Rand, M.K., Sakai, K., Lu, X., Nakamura, K., et al. (1999). Parallel neural networks for learning sequential procedures. Trends in Neurosciences, 22(10), 464-471. (Pubitemid 29447731)
15. Hikosaka, O., Nakamura, K., Sakai, K., & Nakahara, H. (2002). Central mechanisms of motor skill learning. Current Opinion in Neurobiology, 12, 217-222. (Pubitemid 34518343)
16. Hoehn, M.M., & Yahr, M.D. (1967). Parkinsonism: Onset, progression, and mortality. Neurology, 17(5), 427-442.
17. Huang, C., Mattis, P., Tang, C., Perrine, K., Carbon, M., & Eidelberg, D. (2007). Metabolic brain networks associated with cognitive function in Parkinson's disease. NeuroImage, 34, 714-723. (Pubitemid 44827754)
18. Jackson, G.M., Jackson, S.R., Harrison, J., Henderson, L., & Kennard, C. (1995). Serial reaction time learning and Parkinson's disease: Evidence for procedural learning deficit. Neuropsychologia, 33(5), 577-593.
19. Keele, S.W., & Curran, T. (1995). Modularity of sequence learning systems in humans. In E. Covey (Ed.), Neural Representation of Temporal Patterns. New York: Plenum Press.
20. Keele, S.W., Ivry, R., Mayr, U., Hazeltime, E., & Heuer, H. (2003). The cognitive and neural architecture of sequence representation. Psychological Review, 110(2), 316-339. PubMed doi:10.1037/0033-295X.110.2.316 (Pubitemid 37189446)
21. Keilp, J. G., Alexander, G. E., Stern, Y., & Prohovnik. (1996). Inferior parietal perfusion, lateralization, and neuropsychological dysfunction in Alzheimer's disease. Brain and Cognition, 32, 365-383. PubMed doi:10.1006/brcg.1996.0071
22. Knopman, D.S., & Nissen, M.J. (1987). Implicit learning in patients with probable Alzheimer's disease. Neurology, 37, 784-788. (Pubitemid 17064666)
23. Knopman, D. (1991). Long-term retention of implicitly acquired learning in patients with Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology, 13(6), 880-894.
24. Laforce, R., & Doyon, J. (2001). Distinct contribution of the striatum and cerebellum to motor learning. Brain and Cognition, 45, 189-211. (Pubitemid 32216114)
25. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E.M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34, 939-944.
26. Nakahara, H., Doya, K., & Hikosaka, O. (2001). Parallel cortico-basal ganglia mechanisms for acquisition and execution of visuomotor sequences: A computational approach. Journal of Cognitive Neuroscience, 13(5), 626-647.
27. Nelson, H.E., & O'Connell, A. (1978). Dementia: The estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex, 14, 234-244.
28. Nissen, M.J., & Bullemer, P. (1987). Attentional requirements of learning: Evidence from performance measures. Cognitive Psychology, 19, 1-32.
29. Rand, M.K., Hikosaka, O., Miyachi, S., Lu, X., Nakamura, K., Kitaguchi, K., et al. (2000). Characteristics of sequential movements during early learning period in monkeys. Experimental Brain Research, 131, 293-304.
30. Rascovsky, K., Salmon, D.P., Ho, G.J., Galasko, D., Peavy, G.M., Hansen, L.A., et al. (2002). Cognitive profiles differ in autopsy-confirmed frontotemporal dementia and AD. Neurology, 58, 1801-1808. (Pubitemid 34663581)
31. Roncacci, S., Troisi, E., Carlesimo, G.A., Nocentini, U., & Caltagirone, C. (1996). Implicit memory in Parkinsonian patients: Evidence for deficient skill learning. European Neurology, 36, 154-159. (Pubitemid 26129752)
32. Schmand, B., Lindeboom, J., & Van Harskamp, F. (1992). De Nederlandse Leestest voor Volwassenen. Lisse: Swets and Zeitlinger.
33. Siegert, R.J., Taylor, K.D., Weatherall, M., & Abernethy, D.A. (2006). Is implicit sequence learning impaired in Parkinson's disease? A meta-analysis. Neuropsychology, 20(4), 490-495. (Pubitemid 44199168)
34. Smith, J.G., & McDowall, J. (2006). The implicit sequence learning deficit in patients with Parkinson's disease: A matter of impaired sequence integration? Neuropsychologia, 44, 275-288.
35. Spaan, P.E.J., Raaijmakers, J.G.W., & Jonker, C. (2003). Alzheimer's disease versus normal aging: A review of the efficiency of clinical and experimental memory measures. Journal of Clinical and Experimental Neuropsychology, 25(2), 216-233.
36. Sommer, M., Grafman, J., Clark, K., & Hallett, M. (1999). Learning in Parkinson's disease: Eyeblink conditioning, declarative learning, and procedural learning. Journal of Neurology, Neurosurgery, and Psychiatry, 67, 27-34.
37. Stefanova, E. D., Kostic, V. S., Ziropadja, L., Markovic, M., & Ocic, G. G. (2000). Visuomotor skill learning on serial reaction time task in patients with early Parkinson's disease. Movements disorders, 15 (6), 1095-1103.
38. Thomas-Ollivier, V., Reymann, J.M., Le Moal, S., Schück, S., Lieury, A., & Allain, H. (1999). Procedural memory in recent-onset Parkinson's disease. Dementia and Geriatric Cognitive Disorders, 10, 172-180.
39. Van Halteren-Van Tilborg, I.A.D.A., Scherder, E.J.A., & Hulstijn, W. (2007). Motor-skill learning in Alzheimer's disease: A review with an eye to the clinical practice. Neuropsychology Review, 17(3), 203-212. (Pubitemid 47498173)
40. Werheid, K., Ziessler, M., Nattkemper, D., & von Cramon, D.Y. (2003). Sequence learning in Parkinson's disease: The effect of spatial stimulus-response compatibility. Brain and Cognition, 52, 239-249.
41. Werheid, K., Zysset, S., Müller, A., Reuter, M., & von Cramon, D.Y. (2003). Rule learning in a serial reaction time task: An fMRI study on patients with early Parkinson's disease. Brain Research. Cognitive Brain Research, 16, 273-284.
42. Westwater, H., McDowall, J., Siegert, R., Mossman, S., & Abernethy, D. (1998). Implicit learning in Parkinson's disease: Evidence from a verbal version of the serial reaction time task. Journal of Clinical and Experimental Neuropsychology, 20(3), 413-418.
43. Willingham, D.B. (1998). A neuropsychological theory of motor skill learning. Psychological Review, 105, 558-584.
44. Willingham, D.B. (1999). The neural basis of motor-skill learning. Current Directions in Psychological Science, 8(6), 178-182.
45. Willingham, D.B., Nissen, M.J., & Bullemer, P. (1989). On the development of procedural knowledge. Journal of Experimental Psychology. Learning, Memory, and Cognition, 15(6), 1047-1060.
46. Willingham, D.B., Peterson, E.W., Manning, C., & Brashear, H.R. (1997). Patients with Alzheimer's disease who cannot perform some motor skills show normal learning of other motor skills. Neuropsychology, 11(2), 261-271.