Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Müller cells in culture

Diabetes

Volumn 59, Issue 9, 2010, Pages 2107-2116

  Schrufer, Tabitha L ^a   Antonetti, David A ^a   Sonenberg, Nahum ^b   Kimball, Scot R ^a   Gardner, Thomas W ^a   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b Department of Biochemistry McIntyre Medical Science Bldg ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4E BINDING PROTEIN 2; UNCLASSIFIED DRUG; VASCULOTROPIN; CARRIER PROTEIN; EIF4EBP1 PROTEIN, MOUSE; EIF4EBP1 PROTEIN, RAT; EIF4EBP2 PROTEIN, MOUSE; INITIATION FACTOR; INITIATION FACTOR 4E; MESSENGER RNA; PHOSPHOPROTEIN; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETIC RETINOPATHY; FIBROBLAST; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INTERNAL RIBOSOME ENTRY SITE; MALE; MOUSE; MUELLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RETINA; SPRAGUE DAWLEY RAT; ADOLESCENT; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CHILD; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KNOCKOUT MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ANIMALS; CARRIER PROTEINS; CHILD; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTORS; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; HYPERGLYCEMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, GENETIC; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77956374138     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0148     Document Type: Article

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