Arsenic induces apoptosis of human umbilical vein endothelial cells through mitochondrial pathways

Cardiovascular Toxicology

Volumn 10, Issue 3, 2010, Pages 153-160

  Shi, Yanfen ^a   Wei, Yudan ^b   Qu, Shanshan ^a   Wang, Yang ^a   Li, Yulin ^a   Li, Ronggui ^a  

^a Basic Medical College   (China)

^b MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Arsenic; Human umbilical vein endothelial cells; Mitochondria; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ARSENIC; ARSENITE SODIUM; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PURIFICATION; UMBILICAL VEIN;

ANTIOXIDANTS; APOPTOSIS; ARSENITES; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NAD(P)H DEHYDROGENASE (QUINONE); REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SODIUM COMPOUNDS; SUPEROXIDE DISMUTASE; UMBILICAL VEINS;

EID: 77956340663     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12012-010-9073-z     Document Type: Article

References (31)

1. MM Rahman R Naidu P Bhattacharya 2009 Arsenic contamination in groundwater in the Southeast Asia region Environmental Geochemistry and Health 31 Suppl 1 9 21 10.1007/s10653-008-9233-2 1:CAS:528:DC%2BD1MXlslSgu7c%3D 19137402
2. G Yu D Sun Y Zheng 2007 Health effects of exposure to natural arsenic in groundwater and coal in China: An overview of occurrence Environmental Health Perspectives 115 636 642 10.1289/ehp.9268 1:CAS:528:DC%2BD2sXltVKlsLo%3D 17450236
3. G Sun 2004 Arsenic contamination and arsenicosis in China Toxicology and Applied Pharmacology 198 268 271 10.1016/j.taap.2003.10.017 1:CAS:528: DC%2BD2cXmtVaiur8%3D 15276405
4. A Mukherjee MK Sengupta MA Hossain S Ahamed B Das B Nayak D Lodh MM Rahman D Chakraborti 2006 Arsenic contamination in groundwater: A global perspective with emphasis on the Asian scenario Journal of Health, Population, and Nutrition 24 142 163 17195556
5. MM Wu TL Kuo YH Hwang CJ Chen 1989 Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases American Journal of Epidemiology 130 1123 1132 1:STN:280:DyaK3c%2Fnt1Sntw%3D%3D 2589305
6. CC Chang SC Ho SS Tsai CY Yang 2004 Ischemic heart disease mortality reduction in an arseniasis-endemic area in southwestern Taiwan after a switch in the tap-water supply system Journal of Toxicology and Environmental Health: Part A 67 1353 1361 10.1080/15287390490471451 1:CAS:528:DC%2BD2cXmslaktLs%3D
7. A Navas-Acien EK Silbergeld R Pastor-Barriuso E Guallar 2008 Arsenic exposure and prevalence of type 2 diabetes in US adults Jama 300 814 822 10.1001/jama.300.7.814 1:CAS:528:DC%2BD1cXhtVWrur3F 18714061
8. JA Coronado-Gonzalez LM Del Razo G Garcia-Vargas F Sanmiguel-Salazar J Escobedo-de la Pena 2007 Inorganic arsenic exposure and type 2 diabetes mellitus in Mexico Environmental Research 104 383 389 10.1016/j.envres.2007.03.004 1:CAS:528:DC%2BD2sXmtlWisL4%3D 17475235
9. HF Chiu CC Chang SS Tsai CY Yang 2006 Does arsenic exposure increase the risk for diabetes mellitus? Journal of Occupational and Environmental Medicine 48 63 67 10.1097/01.jom.0000184854.75053.03 1:CAS:528:DC%2BD28Xps1Oq 16404211
10. CH Tseng CK Chong CJ Chen TY Tai 1997 Lipid profile and peripheral vascular disease in arseniasis-hyperendemic villages in Taiwan Angiology 48 321 335 10.1177/000331979704800405 1:STN:280:DyaK2s3mslGmsg%3D%3D 9112880
11. CH Tseng YK Huang YL Huang CJ Chung MH Yang CJ Chen YM Hsueh 2005 Arsenic exposure, urinary arsenic speciation, and peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan Toxicology and Applied Pharmacology 206 299 308 10.1016/j.taap.2004.11.022 1:CAS:528: DC%2BD2MXmsVWgurw%3D 16039941
12. CH Tseng CK Chong CJ Chen BJ Lin TY Tai 1995 Abnormal peripheral microcirculation in seemingly normal subjects living in blackfoot-disease- hyperendemic villages in Taiwan International Journal of Microcirculation, Clinical and Experimental 15 21 27 10.1159/000178945 1:STN:280: DyaK28%2FlsFCnuw%3D%3D 7558622
13. CH Tseng CK Chong CJ Chen TY Tai 1996 Dose-response relationship between peripheral vascular disease and ingested inorganic arsenic among residents in blackfoot disease endemic villages in Taiwan Atherosclerosis 120 125 133 10.1016/0021-9150(95)05693-9 1:CAS:528:DyaK28XhtFWrtb4%3D 8645353
14. CH Tseng CK Chong CP Tseng JA Centeno 2007 Blackfoot disease in Taiwan: Its link with inorganic arsenic exposure from drinking water Ambio 36 82 84 10.1579/0044-7447(2007)36[82:BDITIL]2.0.CO;2 1:CAS:528:DC%2BD1cXksFSrs74%3D 17408196
15. P Balakumar J Kaur 2009 Arsenic exposure and cardiovascular disorders: An overview Cardiovascular Toxicology 9 169 176 10.1007/s12012-009-9050-6 1:CAS:528:DC%2BD1MXhsVajt7rM 19787300
16. CH Tseng 2008 Cardiovascular disease in arsenic-exposed subjects living in the arseniasis-hyperendemic areas in Taiwan Atherosclerosis 199 12 18 10.1016/j.atherosclerosis.2008.02.013 1:CAS:528:DC%2BD1cXns1Snsrk%3D 18367191
17. E Mannarino M Pirro 2008 Endothelial injury and repair: A novel theory for atherosclerosis Angiology 59 69S 72S 10.1177/0003319708320761 18628277
18. YH Kao CL Yu LW Chang HS Yu 2003 Low concentrations of arsenic induce vascular endothelial growth factor and nitric oxide release and stimulate angiogenesis in vitro Chemical Research in Toxicology 16 460 468 10.1021/tx025652a 1:CAS:528:DC%2BD3sXit1OntL4%3D 12703962
19. SH Woo MJ Park S An HC Lee HO Jin SJ Lee HS Gwak IC Park SI Hong CH Rhee 2005 Diarsenic and tetraarsenic oxide inhibit cell cycle progression and bFGF- and VEGF-induced proliferation of human endothelial cells Journal of Cellular Biochemistry 95 120 130 10.1002/jcb.20329 1:CAS:528:DC%2BD2MXjvFeisrc%3D 15723287
20. K Ramanathan M Anusuyadevi S Shila C Panneerselvam 2005 Ascorbic acid and alpha-tocopherol as potent modulators of apoptosis on arsenic induced toxicity in rats Toxicology Letters 156 297 306 10.1016/j.toxlet.2004.12.003 1:CAS:528:DC%2BD2MXhvVSnsLw%3D 15737492
21. RH Engel AM Evens 2006 Oxidative stress and apoptosis: A new treatment paradigm in cancer Frontiers in Bioscience 11 300 312 10.2741/1798 1:CAS:528:DC%2BD2MXhtlSrurzE 16146732
22. H Nohl L Gille K Staniek 2005 Intracellular generation of reactive oxygen species by mitochondria Biochemical Pharmacology 69 719 723 10.1016/j.bcp.2004.12.002 1:CAS:528:DC%2BD2MXhtlCrsLo%3D 15710349
23. SX Liu M Athar I Lippai C Waldren TK Hei 2001 Induction of oxyradicals by arsenic: Implication for mechanism of genotoxicity Proceedings of the National Academy of Sciences of the United States of America 98 1643 1648 10.1073/pnas.031482998 1:CAS:528:DC%2BD3MXhsVWjurc%3D 11172004
24. MJ Perez AI Cederbaum 2003 Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity Hepatology 38 1146 1158 10.1053/jhep.2003.50479 1:CAS:528:DC%2BD3sXpsVOntr8%3D 14578853
25. MW Epperly M Bernarding J Gretton M Jefferson S Nie JS Greenberger 2003 Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-alpha, IL-3 withdrawal, and ionizing radiation Experimental Hematology 31 465 474 10.1016/S0301-472X(03) 00041-9 1:CAS:528:DC%2BD3sXkvVKns7c%3D 12829021
26. FM Faraci SP Didion 2004 Vascular protection: Superoxide dismutase isoforms in the vessel wall Arteriosclerosis, Thrombosis, and Vascular Biology 24 1367 1373 10.1161/01.ATV.0000133604.20182.cf 1:CAS:528:DC%2BD2cXmtValtL8%3D 15166009
27. A Gaikwad DJ Long 2nd JL Stringer AK Jaiswal 2001 In vivo role of NAD(P)H:Quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue J Biol Chem 276 22559 22564 10.1074/jbc.M101053200 1:CAS:528:DC%2BD3MXkvVamsLk%3D 11309386
28. P Joseph T Xie Y Xu AK Jaiswal 1994 NAD(P)H:Quinone oxidoreductase1 (DT-diaphorase): Expression, regulation, and role in cancer Oncology Research 6 525 532 1:CAS:528:DyaK2MXlt1enurk%3D 7620221
29. D Ross JK Kepa SL Winski HD Beall A Anwar D Siegel 2000 NAD(P)H:Quinone oxidoreductase 1 (NQO1): Chemoprotection, bioactivation, gene regulation and genetic polymorphisms Chemico-Biological Interactions 129 77 97 10.1016/S0009-2797(00)00199-X 1:CAS:528:DC%2BD3MXitlOntQ%3D%3D 11154736
30. VN Reddy E Kasahara M Hiraoka LR Lin YS Ho 2004 Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium Experimental Eye Research 79 859 868 10.1016/j.exer.2004.04.005 1:CAS:528:DC%2BD2MXhvF2itw%3D%3D 15642323
31. Y Wang Y Xu H Wang P Xue X Li B Li Q Zheng G Sun 2009 Arsenic induces mitochondria-dependent apoptosis by reactive oxygen species generation rather than glutathione depletion in Chang human hepatocytes Archives of Toxicology 83 899 908 10.1007/s00204-009-0451-x 1:CAS:528:DC%2BD1MXntlOgt7Y%3D 19536524