Catalytic digestion of human tumor necrosis factor-α by antibody heavy chain

FEBS Journal

Volumn 277, Issue 18, 2010, Pages 3823-3832

  Hifumi, Emi ^a,b   Higashi, Kyohei ^a   Uda, Taizo ^a,b  

^a OITA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

catalytic antibody; cytokine; proteolysis; TNF

Indexed keywords

CATALYTIC ANTIBODY; COMPLEMENTARY DNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ETNF 6; MYOGLOBIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; FEMALE; HEAVY CHAIN; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN TARGETING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, CATALYTIC; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BASE SEQUENCE; BIOCATALYSIS; CROSS REACTIONS; FEMALE; HUMANS; HYDROLYSIS; IMMUNOGLOBULIN HEAVY CHAINS; KINETICS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956332726     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07785.x     Document Type: Article

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