메뉴 건너뛰기




Volumn 5, Issue 4, 2010, Pages

Enhanced glutamatergic and decreased gabaergic synaptic appositions to GnRH neurons on proestrus in the rat: Modulatory effect of aging

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; GONADORELIN; LUTEINIZING HORMONE; VESICULAR GLUTAMATE TRANSPORTER 2; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; SLC17A6 PROTEIN, RAT; VIAAT PROTEIN, RAT;

EID: 77956330735     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010172     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 24944487970 scopus 로고    scopus 로고
    • Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats
    • Neal-Perry GS, Zeevalk GD, Santoro NF, Etgen AM (2005) Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats. Endocrinology 146: 4331-4339.
    • (2005) Endocrinology , vol.146 , pp. 4331-4339
    • Neal-Perry, G.S.1    Zeevalk, G.D.2    Santoro, N.F.3    Etgen, A.M.4
  • 2
    • 0019132995 scopus 로고
    • Characterization of the LH surge in middle-aged female rats
    • Cooper RL, Conn PM, Walker RF (1980) Characterization of the LH surge in middle-aged female rats. Biol Reprod 23: 611-615.
    • (1980) Biol Reprod , vol.23 , pp. 611-615
    • Cooper, R.L.1    Conn, P.M.2    Walker, R.F.3
  • 3
    • 0020056007 scopus 로고
    • Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats
    • Wise PM (1982) Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats. Proc Soc Exp Biol Med 169: 348-354.
    • (1982) Proc Soc Exp Biol Med , vol.169 , pp. 348-354
    • Wise, P.M.1
  • 4
    • 0029884761 scopus 로고    scopus 로고
    • Decreased gonadotropinreleasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: A possible role in reproductive aging?
    • Zuo Z, Mahesh VB, Zamorano PL, Brann DW (1996) Decreased gonadotropinreleasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: a possible role in reproductive aging? Endocrinology 137: 2334-2338.
    • (1996) Endocrinology , vol.137 , pp. 2334-2338
    • Zuo, Z.1    Mahesh, V.B.2    Zamorano, P.L.3    Brann, D.W.4
  • 5
    • 0026639445 scopus 로고
    • Isolated hypothalami from aging female rats do not exhibit reduced basal or potassium-stimulated secretion of luteinizing hormonereleasing hormone
    • Rubin BS (1992) Isolated hypothalami from aging female rats do not exhibit reduced basal or potassium-stimulated secretion of luteinizing hormonereleasing hormone. Biol Reprod 47: 254-261.
    • (1992) Biol Reprod , vol.47 , pp. 254-261
    • Rubin, B.S.1
  • 6
    • 0027462849 scopus 로고
    • Naloxone stimulates comparable release of luteinizing hormone-releasing hormone from tissue fragments from ovariectomized, estrogen-treated young and middle-aged female rats
    • Rubin BS (1993) Naloxone stimulates comparable release of luteinizing hormone-releasing hormone from tissue fragments from ovariectomized, estrogen-treated young and middle-aged female rats. Brain Res 601: 246-254.
    • (1993) Brain Res , vol.601 , pp. 246-254
    • Rubin, B.S.1
  • 7
    • 0033796835 scopus 로고    scopus 로고
    • Hypothalamic alterations and reproductive aging in female rats: Evidence of altered luteinizing hormone-releasing hormone neuronal function
    • Rubin BS (2000) Hypothalamic alterations and reproductive aging in female rats: evidence of altered luteinizing hormone-releasing hormone neuronal function. Biol Reprod 63: 968-976.
    • (2000) Biol Reprod , vol.63 , pp. 968-976
    • Rubin, B.S.1
  • 8
    • 0029145342 scopus 로고
    • A relative depletion of luteinizing hormone-releasing hormone was observed in the median eminence of young but not middle-aged rats on the evening of proestrus
    • Rubin BS, King JC (1995) A relative depletion of luteinizing hormone-releasing hormone was observed in the median eminence of young but not middle-aged rats on the evening of proestrus. Neuroendocrinology 62: 259-269.
    • (1995) Neuroendocrinology , vol.62 , pp. 259-269
    • Rubin, B.S.1    King, J.C.2
  • 9
    • 0028097227 scopus 로고
    • A reduced proportion of luteinizing hormone (LH)-releasing hormone neurons express Fos protein during the preovulatory or steroid-induced LH surge in middle-aged rats
    • Rubin BS, Lee CE, King JC (1994) A reduced proportion of luteinizing hormone (LH)-releasing hormone neurons express Fos protein during the preovulatory or steroid-induced LH surge in middle-aged rats. Biol Reprod 51: 1264-1272.
    • (1994) Biol Reprod , vol.51 , pp. 1264-1272
    • Rubin, B.S.1    Lee, C.E.2    King, J.C.3
  • 10
    • 0028346636 scopus 로고
    • Decline in immediate early gene expression in gonadotropin-releasing hormone neurons during proestrus in regularly cycling, middle-aged rats
    • Lloyd JM, Hoffman GE, Wise PM (1994) Decline in immediate early gene expression in gonadotropin-releasing hormone neurons during proestrus in regularly cycling, middle-aged rats. Endocrinology 134: 1800-1805.
    • (1994) Endocrinology , vol.134 , pp. 1800-1805
    • Lloyd, J.M.1    Hoffman, G.E.2    Wise, P.M.3
  • 11
    • 0029126523 scopus 로고
    • Reconstructions of populations of luteinizing hormone releasing hormone neurons in young and middle-aged rats reveal progressive increases in subgroups expressing Fos protein on proestrus and age-related deficits
    • Rubin BS, Mitchell S, Lee CE, King JC (1995) Reconstructions of populations of luteinizing hormone releasing hormone neurons in young and middle-aged rats reveal progressive increases in subgroups expressing Fos protein on proestrus and age-related deficits. Endocrinology 136: 3823-3830.
    • (1995) Endocrinology , vol.136 , pp. 3823-3830
    • Rubin, B.S.1    Mitchell, S.2    Lee, C.E.3    King, J.C.4
  • 12
    • 0034751111 scopus 로고    scopus 로고
    • Parallel declines in Fos activation of the medial anteroventral periventricular nucleus and LHRH neurons in middle-aged rats
    • Le WW, Wise PM, Murphy AZ, Coolen LM, Hoffman GE (2001) Parallel declines in Fos activation of the medial anteroventral periventricular nucleus and LHRH neurons in middle-aged rats. Endocrinology 142: 4976-4982.
    • (2001) Endocrinology , vol.142 , pp. 4976-4982
    • Le, W.W.1    Wise, P.M.2    Murphy, A.Z.3    Coolen, L.M.4    Hoffman, G.E.5
  • 13
    • 0030800768 scopus 로고    scopus 로고
    • Excitatory amino acids: Evidence for a role in the control of reproduction and anterior pituitary hormone secretion
    • Brann DW, Mahesh VB (1997) Excitatory amino acids: evidence for a role in the control of reproduction and anterior pituitary hormone secretion. Endocr Rev 18: 678-700.
    • (1997) Endocr Rev , vol.18 , pp. 678-700
    • Brann, D.W.1    Mahesh, V.B.2
  • 14
    • 0025237351 scopus 로고
    • A role for N-methyl-D-aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty
    • Urbanski HF, Ojeda SR (1990) A role for N-methyl-D-aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty. Endocrinology 126: 1774-1776.
    • (1990) Endocrinology , vol.126 , pp. 1774-1776
    • Urbanski, H.F.1    Ojeda, S.R.2
  • 15
    • 0026073027 scopus 로고
    • Effect on luteinizing hormone secretion of GABA receptor modulation in the medial preoptic area at the time of proestrous luteinizing hormone surge
    • Herbison AE, Dyer RG (1991) Effect on luteinizing hormone secretion of GABA receptor modulation in the medial preoptic area at the time of proestrous luteinizing hormone surge. Neuroendocrinology 53: 317-320.
    • (1991) Neuroendocrinology , vol.53 , pp. 317-320
    • Herbison, A.E.1    Dyer, R.G.2
  • 16
    • 0035050437 scopus 로고    scopus 로고
    • A conditional tetracycline-regulated increase in Gamma amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat
    • Bilger M, Heger S, Brann DW, Paredes A, Ojeda SR (2001) A conditional tetracycline-regulated increase in Gamma amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat. Endocrinology 142: 2102-2114.
    • (2001) Endocrinology , vol.142 , pp. 2102-2114
    • Bilger, M.1    Heger, S.2    Brann, D.W.3    Paredes, A.4    Ojeda, S.R.5
  • 17
    • 0035231594 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) neurons: Mechanism of pulsatile LHRH release
    • Terasawa E (2001) Luteinizing hormone-releasing hormone (LHRH) neurons: mechanism of pulsatile LHRH release. Vitam Horm 63: 91-129.
    • (2001) Vitam Horm , vol.63 , pp. 91-129
    • Terasawa, E.1
  • 18
    • 4444314160 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase 67 (GAD67) gene expression in discrete regions of the rostral preoptic area change during the oestrous cycle and with age
    • Cashion AB, Smith MJ, Wise PM (2004) Glutamic acid decarboxylase 67 (GAD67) gene expression in discrete regions of the rostral preoptic area change during the oestrous cycle and with age. J Neuroendocrinol 16: 711-716.
    • (2004) J Neuroendocrinol , vol.16 , pp. 711-716
    • Cashion, A.B.1    Smith, M.J.2    Wise, P.M.3
  • 19
    • 0842313108 scopus 로고    scopus 로고
    • Endogenous GABA release inhibits the firing of adult gonadotropin-releasing hormone neurons
    • Han SK, Todman MG, Herbison AE (2004) Endogenous GABA release inhibits the firing of adult gonadotropin-releasing hormone neurons. Endocrinology 145: 495-499.
    • (2004) Endocrinology , vol.145 , pp. 495-499
    • Han, S.K.1    Todman, M.G.2    Herbison, A.E.3
  • 20
    • 12244253710 scopus 로고    scopus 로고
    • Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons
    • DeFazio RA, Heger S, Ojeda SR, Moenter SM (2002) Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. Mol Endocrinol 16: 2872-2891.
    • (2002) Mol Endocrinol , vol.16 , pp. 2872-2891
    • DeFazio, R.A.1    Heger, S.2    Ojeda, S.R.3    Moenter, S.M.4
  • 21
    • 68049139663 scopus 로고    scopus 로고
    • GABAA receptors mediate excitation in adult rat GnRH neurons
    • Watanabe M, Sakuma Y, Kato M (2009) GABAA receptors mediate excitation in adult rat GnRH neurons. Biol Reprod 81: 327-332.
    • (2009) Biol Reprod , vol.81 , pp. 327-332
    • Watanabe, M.1    Sakuma, Y.2    Kato, M.3
  • 22
    • 0028047383 scopus 로고
    • GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GT1-7) neurons
    • Hales TG, Sanderson MJ, Charles AC (1994) GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GT1-7) neurons. Neuroendocrinology 59: 297-308.
    • (1994) Neuroendocrinology , vol.59 , pp. 297-308
    • Hales, T.G.1    Sanderson, M.J.2    Charles, A.C.3
  • 24
    • 0035021311 scopus 로고    scopus 로고
    • GABA inhibition of immortalized gonadotropin-releasing hormone neuronal excitability involves GABA(A) receptors negatively coupled to cyclic adenosine monophosphate formation
    • Beltran-Parrazal L, Noris G, Clapp C, Martinez de la Escalera G (2001) GABA inhibition of immortalized gonadotropin-releasing hormone neuronal excitability involves GABA(A) receptors negatively coupled to cyclic adenosine monophosphate formation. Endocrine 14: 189-195.
    • (2001) Endocrine , vol.14 , pp. 189-195
    • Beltran-Parrazal, L.1    Noris, G.2    Clapp, C.3    Martinez de la Escalera, G.4
  • 25
    • 66449115039 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid B receptor mediated inhibition of gonadotropin-releasing hormone neurons is suppressed by kisspeptin-G protein-coupled receptor 54 signaling
    • Zhang C, Bosch MA, Ronnekleiv OK, Kelly MJ (2009) Gamma-aminobutyric acid B receptor mediated inhibition of gonadotropin-releasing hormone neurons is suppressed by kisspeptin-G protein-coupled receptor 54 signaling. Endocrinology 150: 2388-2394.
    • (2009) Endocrinology , vol.150 , pp. 2388-2394
    • Zhang, C.1    Bosch, M.A.2    Ronnekleiv, O.K.3    Kelly, M.J.4
  • 26
    • 0018880920 scopus 로고
    • Effects of discrete lesions of preoptic and suprachiasmatic structures in the female rat. Alterations in the feedback regulation of gonadotropin secretion
    • Wiegand SJ, Terasawa E, Bridson WE, Goy RW (1980) Effects of discrete lesions of preoptic and suprachiasmatic structures in the female rat. Alterations in the feedback regulation of gonadotropin secretion. Neuroendocrinology 31: 147-157.
    • (1980) Neuroendocrinology , vol.31 , pp. 147-157
    • Wiegand, S.J.1    Terasawa, E.2    Bridson, W.E.3    Goy, R.W.4
  • 27
    • 0345601727 scopus 로고    scopus 로고
    • Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol
    • Petersen SL, Ottem EN, Carpenter CD (2003) Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol. Biol Reprod 69: 1771-1778.
    • (2003) Biol Reprod , vol.69 , pp. 1771-1778
    • Petersen, S.L.1    Ottem, E.N.2    Carpenter, C.D.3
  • 28
    • 4644225041 scopus 로고    scopus 로고
    • Dual-phenotype GABA/glutamate neurons in adult preoptic area: Sexual dimorphism and function
    • Ottem EN, Godwin JG, Krishnan S, Petersen SL (2004) Dual-phenotype GABA/glutamate neurons in adult preoptic area: sexual dimorphism and function. J Neurosci 24: 8097-8105.
    • (2004) J Neurosci , vol.24 , pp. 8097-8105
    • Ottem, E.N.1    Godwin, J.G.2    Krishnan, S.3    Petersen, S.L.4
  • 29
    • 0034923251 scopus 로고    scopus 로고
    • An inexpensive meter to measure differences in electrical resistance in the rat vagina during the ovarian cycle
    • Ramos SD, Lee JM, Peuler JD (2001) An inexpensive meter to measure differences in electrical resistance in the rat vagina during the ovarian cycle. J Appl Physiol 91: 667-670.
    • (2001) J Appl Physiol , vol.91 , pp. 667-670
    • Ramos, S.D.1    Lee, J.M.2    Peuler, J.D.3
  • 30
    • 27844445651 scopus 로고    scopus 로고
    • Cloning, expression, and localization of MNAR/PELP1 in rodent brain: Colocalization in estrogen receptor-alpha- but not in gonadotropin-releasing hormone-positive neurons
    • Khan MM, Hadman M, Wakade C, De Sevilla LM, Dhandapani KM, et al. (2005) Cloning, expression, and localization of MNAR/PELP1 in rodent brain: colocalization in estrogen receptor-alpha- but not in gonadotropin-releasing hormone-positive neurons. Endocrinology 146: 5215-5227.
    • (2005) Endocrinology , vol.146 , pp. 5215-5227
    • Khan, M.M.1    Hadman, M.2    Wakade, C.3    De Sevilla, L.M.4    Dhandapani, K.M.5
  • 31
    • 70449397081 scopus 로고    scopus 로고
    • Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation
    • Zhang QG, Raz L, Wang R, Han D, De Sevilla L, et al. (2009) Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. J Neurosci 29: 13823-13836.
    • (2009) J Neurosci , vol.29 , pp. 13823-13836
    • Zhang, Q.G.1    Raz, L.2    Wang, R.3    Han, D.4    De Sevilla, L.5
  • 33
    • 0035891724 scopus 로고    scopus 로고
    • Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2)
    • Takamori S, Rhee JS, Rosenmund C, Jahn R (2001) Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2). J Neurosci 21: RC182.
    • (2001) J Neurosci , vol.21
    • Takamori, S.1    Rhee, J.S.2    Rosenmund, C.3    Jahn, R.4
  • 34
    • 55549126867 scopus 로고    scopus 로고
    • Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area
    • Neal-Perry GS, Zeevalk GD, Shu J, Etgen AM (2008) Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area. Biol Reprod 79: 878-888.
    • (2008) Biol Reprod , vol.79 , pp. 878-888
    • Neal-Perry, G.S.1    Zeevalk, G.D.2    Shu, J.3    Etgen, A.M.4
  • 35
    • 15244350751 scopus 로고    scopus 로고
    • The aging reproductive neuroendocrine axis
    • Brann DW, Mahesh VB (2005) The aging reproductive neuroendocrine axis. Steroids 70: 273-283.
    • (2005) Steroids , vol.70 , pp. 273-283
    • Brann, D.W.1    Mahesh, V.B.2
  • 36
    • 0030936499 scopus 로고    scopus 로고
    • Bicuculline infusion advances the timing of Fos expression in LHRH neurons in the preoptic area of proestrous rats
    • Funabashi T, Jinnai K, Kimura F (1997) Bicuculline infusion advances the timing of Fos expression in LHRH neurons in the preoptic area of proestrous rats. Neuroreport 8: 771-774.
    • (1997) Neuroreport , vol.8 , pp. 771-774
    • Funabashi, T.1    Jinnai, K.2    Kimura, F.3
  • 37
    • 0027253698 scopus 로고
    • Possible Role of Non-NMDA Receptor- Mediated Neurotransmission in Steroid-Induced and Preovulatory Gonadotropin Surges in the Rat
    • Brann DW, Ping L, Mahesh VB (1993) Possible Role of Non-NMDA Receptor- Mediated Neurotransmission in Steroid-Induced and Preovulatory Gonadotropin Surges in the Rat. Mol Cell Neurosci 4: 292-297.
    • (1993) Mol Cell Neurosci , vol.4 , pp. 292-297
    • Brann, D.W.1    Ping, L.2    Mahesh, V.B.3
  • 38
    • 0024580290 scopus 로고
    • Alterations in luteinizing hormone-releasing hormone release from the mediobasal hypothalamus of ovariectomized, steroidprimed middle-aged rats as measured by push-pull perfusion
    • Rubin BS, Bridges RS (1989) Alterations in luteinizing hormone-releasing hormone release from the mediobasal hypothalamus of ovariectomized, steroidprimed middle-aged rats as measured by push-pull perfusion. Neuroendocrinology 49: 225-232.
    • (1989) Neuroendocrinology , vol.49 , pp. 225-232
    • Rubin, B.S.1    Bridges, R.S.2
  • 39
    • 51449107874 scopus 로고    scopus 로고
    • Expression and activation of N-methyl-Daspartate receptor subunit-1 receptor subunits in gonadotrophin-releasing hormone neurones of young and middle-aged mice during the luteinising hormone surge
    • Adjan V, Centers A, Jennes L (2008) Expression and activation of N-methyl-Daspartate receptor subunit-1 receptor subunits in gonadotrophin-releasing hormone neurones of young and middle-aged mice during the luteinising hormone surge. J Neuroendocrinol 20: 1147-1154.
    • (2008) J Neuroendocrinol , vol.20 , pp. 1147-1154
    • Adjan, V.1    Centers, A.2    Jennes, L.3
  • 40
    • 0023411730 scopus 로고
    • Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area
    • Witkin JW (1987) Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area. Neuroscience 22: 1003-1013.
    • (1987) Neuroscience , vol.22 , pp. 1003-1013
    • Witkin, J.W.1
  • 41
    • 0037229992 scopus 로고    scopus 로고
    • The morphometry of astrocytes in the rostral preoptic area exhibits a diurnal rhythm on proestrus: Relationship to the luteinizing hormone surge and effects of age
    • Cashion AB, Smith MJ, Wise PM (2003) The morphometry of astrocytes in the rostral preoptic area exhibits a diurnal rhythm on proestrus: relationship to the luteinizing hormone surge and effects of age. Endocrinology 144: 274-280.
    • (2003) Endocrinology , vol.144 , pp. 274-280
    • Cashion, A.B.1    Smith, M.J.2    Wise, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.