Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model

Transfusion

Volumn 50, Issue 9, 2010, Pages 2016-2025

  Brinc, Davor ^a   Le Tien, Hoang ^a   Crow, Andrew R ^a   Semple, John W ^a   Freedman, John ^a   Lazarus, Alan H ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; DIPHTHERIA TETANUS VACCINE; EGG WHITE; IMMUNOGLOBULIN G; LYSOZYME; TETANUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; HEN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNIZATION; MOUSE; NONHUMAN; OPSONIZATION; SHEEP;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; IMMUNOGLOBULIN G; IMMUNOSUPPRESSION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL;

EID: 77956323518     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2010.02645.x     Document Type: Article

References (55)

1. Hjelm F, Carlsson F, Getahun A, Heyman B. Antibody-mediated regulation of the immune response. Scand J Immunol 2006 64 : 177 84.
2. Rowley DA, Fitch FW. Homeostasis of antibody formation in the adult rat. J Exp Med 1964 120 : 987 1005.
3. Moeller G, Wigzell H. Antibody synthesis at the cellular level. Antibody-induced suppression of 19S and 7S antibody response. J Exp Med 1965 121 : 969 89.
4. Henry C, Jerne NK. Competition of 19S and 7S antigen receptors in the regulation of the primary immune response. J Exp Med 1968 128 : 133 52.
5. Smith GN, Mollison PL. Suppression of primary immunization to the rabbit red cell alloantigen HgA by passively administered anti-HgA. Immunology 1974 26 : 885 92.
6. Terness P, Susal C, Opelz G. IgG-anti-immunoglobulin induced by immunization with antibody-coated blood cells: mechanism for B-cell suppression? Transplant Proc 1989 21 : 153 5.
7. Susal C, Terness P, Opelz G. An experimental model for preventing alloimmunization against platelet transfusions by pretreatment with antibody-coated cells. Vox Sang 1990 59 : 209 15.
8. Crow AR, Freedman J, Hannach B, Blanchette V, Lazarus AH. Antibody-mediated inhibition of the human alloimmune response to platelet transfusion in Hu-PBL-SCID mice. Br J Haematol 1999 104 : 919 24.
9. Crow AR, Freedman J, Hannach B, Lazarus AH. Monoclonal antibody-mediated inhibition of the human HLA alloimmune response to platelet transfusion is antigen specific and independent of Fcgamma receptor-mediated immune suppression. Br J Haematol 2000 110 : 481 7.
10. Feldmann M, Diener E. Antibody-mediated suppression of the immune response in vitro. I. Evidence for a central effect. J Exp Med 1970 131 : 247 74.
11. Finkelstein MS, Uhr JW. Specific inhibition of antibody formation by passively administered 19s and 7s antibody. Science 1964 146 : 67 9.
12. Barrios C, Brawand P, Berney M, Brandt C, Lambert PH, Siegrist CA. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting. Eur J Immunol 1996 26 : 1489 96.
13. Siegrist CA, Cordova M, Brandt C, Barrios C, Berney M, Tougne C, Kovarik J, Lambert PH. Determinants of infant responses to vaccines in presence of maternal antibodies. Vaccine 1998 16 : 1409 14.
14. Uhr JW, Baumann JB. Antibody formation. I. The suppression of antibody formation by passively administered antibody. J Exp Med 1961 113 : 935 57.
15. Sahiar K, Schwartz RS. Inhibition of 19s antibody synthesis by 7s antibody. Science 1964 145 : 395 7.
16. Brody NI, Walker JG, Siskind GW. Studies on the control of antibody synthesis. Interaction of antigenic competition and suppression of antibody formation by passive antibody on the immune response. J Exp Med 1967 126 : 81 91.
17. Dixon FJ, Jacot-Guillarmod H, McConahey PJ. The effect of passively administered antibody on antibody synthesis. J Exp Med 1967 125 : 1119 35.
18. Siegrist CA, Barrios C, Martinez X, Brandt C, Berney M, Córdova M, Kovarik J, Lambert PH. Influence of maternal antibodies on vaccine responses: inhibition of antibody but not T cell responses allows successful early prime-boost strategies in mice. Eur J Immunol 1998 28 : 4138 48.
19. Kumpel BM, Elson CJ. Mechanism of anti-D-mediated immune suppression - a paradox awaiting resolution? Trends Immunol. 2001 22 : 26 31.
20. Kappler JW, Hoffmann M, Dutton RW. Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med 1971 134 : 577 87.
21. Brinc D, Le-Tien H, Crow AR, Siragam V, Freedman J, Lazarus AH. Transfusion of IgG-opsonized foreign red blood cells mediates reduction of antigen-specific B cell priming in a murine model. J Immunol 2008 181 : 948 53.
22. Sinclair N, Chan P. Regulation of the immune response. IV. The role of the Fc-fragment in feedback inhibition by antibody. Adv Exp Med Biol 1971 12 : 609 15.
23. Karlsson MC, Getahun A, Heyman B. FcgammaRIIB in IgG-mediated suppression of antibody responses: different impact in vivo and in vitro. J Immunol 2001 167 : 5558 64.
24. Karlsson MC, Wernersson S, Diaz de Stahl T, Gustavsson S, Heyman B. Efficient IgG-mediated suppression of primary antibody responses in Fcgamma receptor-deficient mice. Proc Natl Acad Sci USA 1999 96 : 2244 9.
25. Heyman B, Wigzell H. Specific IgM enhances and IgG inhibits the induction of immunological memory in mice. Scand J Immunol 1985 21 : 255 66.
26. Gans HA, Maldonado Y, Yasukawa LL, Beeler J, Audet S, Rinki MM, DeHovitz R, Arvin AM. IL-12, IFN-gamma, and T cell proliferation to measles in immunized infants. J Immunol 1999 162 : 5569 75.
27. Pabst HF, Spady DW, Carson MM, Krezolek MP, Barreto L, Wittes RC. Cell-mediated and antibody immune responses to AIK-C and Connaught monovalent measles vaccine given to 6 month old infants. Vaccine 1999 17 : 1910 8.
28. Brinc D, Le-Tien H, Crow AR, Freedman J, Lazarus AH. IgG-mediated immunosuppression is not dependent on erythrocyte clearance or immunological evasion: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the newborn? Br J Haematol 2007 139 : 275 9.
29. Safford JW Jr., Tokuda S. Antibody-mediated suppression of the immune response: effect on the development of immunologic memory. J Immunol 1971 107 : 1213 25.
30. Brinc D, Le-Tien H, Crow AR, Siragam V, Freedman J, Lazarus AH. Immunoglobulin G-mediated regulation of the murine immune response to transfused red blood cells occurs in the absence of active immune suppression: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the fetus and newborn? Immunology 2008 124 : 141 6.
31. Kumpel BM. On the immunologic basis of Rh immune globulin (anti-D) prophylaxis. Transfusion 2006 46 : 1652 6.
32. Siegrist CA. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine 2003 21 : 3406 12.
33. Haughton G, Nash DR. Specific immunosuppression by minute doses of passive antibody. Transplant Proc 1969 1 : 616 8.
34. Kumpel BM, Judson PA. Quantification of IgG anti-D bound to D-positive red cells infused into D-negative subjects after intramuscular injection of monoclonal anti-D. Transfus Med 1995 5 : 105 12.
35. Kumpel BM, Goodrick MJ, Pamphilon DH, Fraser ID, Poole GD, Morse C, Standen GR, Chapman GE, Thomas DP, Anstee DJ. Human Rh D monoclonal antibodies (BRAD-3 and BRAD-5) cause accelerated clearance of Rh D+ red blood cells and suppression of Rh D immunization in Rh D- volunteers. Blood 1995 86 : 1701 9.
36. Bruggemann M, Rajewsky K. Regulation of the antibody response against hapten-coupled erythrocytes by monoclonal antihapten antibodies of various isotypes. Cell Immunol 1982 71 : 365 73.
37. Woodrow JC, Clarke CA, Donohow WT, Finn R, McConnell RB, Sheppard PM, Lehane D, Roberts FM, Gimlette TM. Mechanism of Rh prophylaxis: an experimental study on specificity of immunosuppression. Br Med J 1975 2 : 57 9.
38. Heyman B. Regulation of antibody responses via antibodies, complement, and Fc receptors. Annu Rev Immunol 2000 18 : 709 37.
39. Cohen PL, Cheek RL, Hadler JA, Yount WJ, Eisenberg RA. The subclass distribution of human IgG rheumatoid factor. J Immunol 1987 139 : 1466 71.
40. Sinclair NR, Lees RK, Elliott EV. Role of the Fc fragment in the regulation of the primary immune response. Nature 1968 220 : 1048 9.
41. Kim BS, Jang YS. Constraints in antigen processing result in unresponsiveness to a T cell epitope of hen egg lysozyme in C57BL/6 mice. Eur J Immunol 1992 22 : 775 82.
42. Uhr JW, Moller G. Regulatory effect of antibody on the immune response. Adv Immunol 1968 8 : 81 127.
43. Heyman B, Wigzell H. Immunoregulation by monoclonal sheep erythrocyte-specific IgG antibodies: suppression is correlated to level of antigen binding and not to isotype. J Immunol 1984 132 : 1136 43.
44. Fleire SJ, Goldman JP, Carrasco YR, Weber M, Bray D, Batista FD. B cell ligand discrimination through a spreading and contraction response. Science 2006 312 : 738 41.
45. Arana E, Vehlow A, Harwood NE, Vigorito E, Henderson R, Turner M, Tybulewicz VL, Batista FD. Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity 2008 28 : 88 99.
46. Lin KB, Freeman SA, Zabetian S, Brugger H, Weber M, Lei V, Dang-Lawson M, Tse KW, Santamaria R, Batista FD, Gold MR. The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands. Immunity 2008 28 : 75 87.
47. Watts C, Lanzavecchia A. Suppressive effect of antibody on processing of T cell epitopes. J Exp Med 1993 178 : 1459 63.
48. Meyer K. Ueber das verhalten der Hammelbutimmunsera gegenuber den Lipoiden aus Organen vom heterogenetischen Typus Z. Immuntat-Sforch Exp Therap 1922 34 : 235 9.
49. Waaler E. On the occurrence of a factor in human serum activating the specific agglutination of sheep blood corpuscules. Acta Pathol Microbiol Scand 1940 1 : 172 88.
50. Pike RM, Sulkin SE, Coggeshall HC. Concerning the nature of the factor in rheumatoid-arthritis serum responsible for increased agglutination of sensitized sheep erythrocytes. J Immunol 1949 63 : 447 63.
51. Pike RM, Sulkin SE, Coggeshall HC. Serological reactions in rheumatoid arthritis; factors affecting the agglutination of sensitized sheep erythrocytes in rheumatiod-arthritis serum. J Immunol 1949 63 : 441 6.
52. Franklin EC, Holman HR, Muller-Eberhard HJ, Kunkel HG. An unusual protein component of high molecular weight in the serum of certain patients with rheumatoid arthritis. J Exp Med 1957 105 : 425 38.
53. Roosnek E, Lanzavecchia A. Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells. J Exp Med 1991 173 : 487 9.
54. Dorner T, Egerer K, Feist E, Burmester GR. Rheumatoid factor revisited. Curr Opin Rheumatol 2004 16 : 246 53.
55. Kumpel BM. Efficacy of RhD monoclonal antibodies in clinical trials as replacement therapy for prophylactic anti-D immunoglobulin: more questions than answers. Vox Sang 2007 93 : 99 111.