Inactivation of DNA-binding response regulator Sak189 abrogates β-antigen expression and affects virulence of Streptococcus agalactiae

PLoS ONE

Volumn 5, Issue 4, 2010, Pages

  Rozhdestvenskaya, Anastasia S ^a   Totolian, Artem A ^a   Dmitriev, Alexander V ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BETA ANTIGEN; ERYTHROMYCIN; PROTEIN HISTIDINE KINASE; SAK189 PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ANTIGEN EXPRESSION; ARTICLE; BAC GENE; BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SAK188 GENE; SAK189 GENE; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS INFECTION; ANIMAL; BACTERIAL GENOME; CATTLE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PATHOGENICITY; VIRULENCE;

STREPTOCOCCUS AGALACTIAE;

ANIMALS; CATTLE; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; HUMANS; STREPTOCOCCUS AGALACTIAE; TRANSCRIPTION, GENETIC; VIRULENCE; VIRULENCE FACTORS;

EID: 77956322142     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010212     Document Type: Article

References (44)

1. Keefe GP (1997) Streptococcus agalactiae mastitis: a review. Can Vet J 38(7): 429-437.
2. Facklam RR, Washington JA (1991) Streptococcus and related catalase-negative gram-positive cocci. In: Balows A, et al. eds. Manual of Clinical Microbiology. American Society for Microbiology. pp 238-239.
3. Stock AM, Robinson VL, Goudreau PN (2000) Two-component signal transduction. Annu Rev Biochem 69: 183-215.
4. Lamarche MG, Wanner BL, Crépin S, Harel J (2008) The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis. FEMS Microbiol Rev 32(3): 461-473.
5. Kleerebezem M, Quadri LE, Kuipers OP, de Vos WM (1997) Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol Microbiol 24(5): 895-904.
6. Glaser P, Rusniok C, Buchrieser C, Chevalier F, Frangeul L, et al. (2002) Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease. Mol Microbiol 45(6): 1499-1513.
7. Tettelin H, Masignani V, Cieslewicz MJ, Eisen JA, Peterson S, et al. (2002) Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A 99(19): 12391-12396.
8. Lamy MC, Zouine M, Fert J, Vergassola M, Couve E, et al. (2004) CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence. Mol Microb 54(5): 1250-1268.
9. Jiang SM, Cieslewicz MJ, Kasper DL, Wessels MR (2005) Regulation of virulence by a two-component system in Group B Streptococcus. J Bacteriol 187(3): 1105-1113.
10. Jiang SM, Ishmael N, Hotopp JD, Puliti M, Tissi L, et al. (2008) Variation in the Group B Streptococcus CsrRS regulon and effects on pathogenity. J Bacteriol 190(6): 1956-1965.
11. Poyart C, Lamy MC, Boumaila C, Fiedler F, Trieu-Cuot P (2001) Regulation of D-alanyl-lipoteichoic acid biosynthesis in Streptococcus agalactiae involves a novel two-component regulatory system. J Bacteriol 183(21): 6324-6334.
12. Spellerberg B, Pozdzinski E, Martin S, Weber-Heynemann J, Lü tticken R (2002) rgf encodes a novel two-component signal transduction system of Streptococcus agalactiae. Infect Immun 70(5): 2434-2440.
13. Dmitriev A, Yang YN, Shen AD, Totolian A (2006) Adjacent location of bac gene and two-component regulatory system genes within the putative Streptococcus agalactiae pathogenicity island. Folia Microbiol (Praha) 51(3): 229-235.
14. Tettelin H, Masignani V, Cieslewicz MJ, Donati C, Medini D, et al. (2005) Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". Proc Natl Acad Sci U S A 102(39): 13950-13955.
15. Areschoug T, Stalhammar-Carlemalm M, Karlsson I, Lindahl G (2002) Streptococcal b protein has separate binding sites for human factor H and IgA-Fc. J Biol Chem 277(15): 12642-12648.
16. Hoskins JA, Alborn W Jr., Arnold J, Blaszczak L, Burgett S, et al. (2001) Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol 183(19): 5709-5717.
17. Lanie JA, Ng WL, Kazmierczak KM, Andrzejewski TM, Davidsen TM, et al. (2007) Genome sequence of avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6. J Bacteriol 189(1): 38-51.
18. Dopazo J, Mendoza A, Herrero J, Caldara F, Humbert Y, et al. (2001) Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate. Microb Drug Resist 7(2): 99-125.
19. Tettelin H, Nelson KE, Paulsen IT, Eisen JA, Read TD, et al. (2001) Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science 293(5529): 498-506.
20. Jedrzejas MJ (2001) Pneumococcal virulence factors: structure and function. Microbiol Mol Biol Rev 65(2): 187-207.
21. Murdoch C, Read RC, Zhang Q, Finn A (2002) Choline-binding protein A of Streptococcus pneumoniae elicits chemokine production and expression of intercellular adhesion molecule 1 (CD54) by human alveolar epithelial cells. J Infect Dis 186(9): 1253-1260.
22. Standish AJ, Stroeher UH, Paton JC (2005) The two-component signal transduction system RR06/HK06 regulates expression of cbpA in Streptococcus pneumoniae. Proc Natl Acad Sci U S A 102(21): 7701-7706.
23. Ma Z, Zhang JR (2007) RR06 Activates Transcription of spr1996 and cbpA in Streptococcus pneumoniae. J Bacteriol 189(6): 2497-2509.
24. Standish AJ, Stroeher UH, Paton JC (2007) The pneumococcal two-component signal transduction system RR/HK06 regulates CbpA and PspA by two distinct mechanisms. J Bacteriol 189(15): 5591-5600.
25. ManiatisT, Fritsch EE, Sambrook J (1982) Molecular cloning. A laboratory manual. Cold Spring Harbor Laboratory. 560 p.
26. Johnson DR, Kaplan EL, Sramek J, Bicova R, Havlicek J, et al. (1996) Laboratory diagnosis of group A streptococcal infections. Geneva: World Health Organization. 111 p.
27. Grubb AO, Grubb RE, Christensen PB, Shalen C (1982) Isolation and some properties of an IgG binding protein from group A streptococci type 15. Int Arch Allergy Appl Immunol 67: 369-376.
28. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227(5259): 680-685.
29. Towbin H, Staehelin T, Gordon J (1992) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979. Biotechnology 24: 145-149.
30. Panda B, Iruretagoyena I, Stiller R, Panda A (2009) Antibiotic resistance and penicillin tolerance in ano-vaginal group B streptococci. J Matern Fetal Neonatal Med 22(2): 111-114.
31. Dogan B, Schukken YH, Santisteban C, Boor KJ (2005) Distribution of serotypes and antimicrobial resistance genes among Streptococcus agalactiae isolates from bovine and human hosts. J Clin Microbiol 43(12): 5899-5906.
32. Kong F, Gidding HF, Berner R, Gilbert GL (2006) Streptococcus agalactiae Cbeta protein gene (bac) sequence types, based on the repeated region of the cell-wall domain: relationship to virulence and a proposed standardized nomenclature. J Med Microbiol 55(7): 829-837.
33. Framson PE, Nittayajarn A, Merry J (1997) New genetic techniques for group B streptococci: high-efficiency transformation, maintenance of temperaturesensitive pWV01 plasmids, and mutagenesis with Tn917. Appl Environ Microbiol 63(9): 3539-3547.
34. Dmitriev A, Tkáciková L, Suvorov A, Kanti{dotless}́ková M, Mikula I, et al. (1999) Comparative genetic study of group B streptococcal strains of human and bovine origin. Folia Microbiol 44(4): 449-453.
35. Berner R, Ruess M, Bereswill S, Brandis M (2002) Polymorphisms in the cell wall-spanning domain of the C protein beta-antigen in clinical Streptococcus agalactiae isolates are caused by genetic instability of repeating DNA sequences. Pediatr Res 51(1): 106-111.
36. Nagano N, Nagano Y, Taguchi F (2002) High expression of a C protein beta antigen gene among invasive strains from certain clonally related groups of type Ia and Ib group B streptococci. Infect Immun 70(8): 4643-4649.
37. Dmitriev A, Hu YY, Shen AD, Suvorov A, Yang YH (2002) Chromosomal analysis of group B streptococcal clinical strains; bac gene-positive strains are genetically homogenous. FEMS Microbiol Lett 208(1): 93-98.
38. Leont'eva GF, Suvorov AN, Meringova LF, Grabovskaia KB, Ustinovich IA, et al. (2005) Experimental evaluation of recombinant polypeptides as Streptococcus Group B vaccine. Zh Mikrobiol Epidemiol Immunobiol 2: 35-40.
39. Nagano N, Nagano Y, Nakano R, Okamoto R, Inoue M (2006) Genetic diversity of the C protein beta-antigen gene and its upstream regions within clonally related groups of type Ia and Ib group B streptococci. Microbiology 152(3): 771-778.
40. Brady LJ, Boyle P (1989) Identification of non-immunoglobulin A-Fc-binding forms and low-molecular-weight secreted forms of the group B streptococcal beta antigen. Infect Immun 57(5): 1573-1581.
41. Hynes W, Johnson C, Stokes M (2009) A single nucleotide mutation results in loss of enzymatic activity in the hyaluronate lyase gene of Streptococcus pyogenes. Microb Pathog 47(6): 308-313.
42. Graham MR, Smoot LM, Migliaccio CA, Virtaneva K, Sturdevant DE, et al. (2002) Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci U S A 99(21): 13855-13860.
43. Rogasch K, Rühmling V, Pané-Farré J, Höper D, Weinberg C, et al. (2006) Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains. J Bacteriol 188(22): 7742-7758.
44. Jerlstrom PG, Chhatwal GS, Timmis KN (1991) The IgA-binding beta antigen of the c protein complex of Group B streptococci: sequence determination of its gene and detection of two binding regions. Mol Microbiol 5(4): 843-849.