γδ T lymphocytes kill T regulatory cells through CD1d

Immunology

Volumn 131, Issue 2, 2010, Pages 202-209

  Huber, Sally A ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

infection; inflammation; innate immunity; myocarditis

Indexed keywords

CD1D ANTIGEN; CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; COXSACKIE VIRUS B3; FLOW CYTOMETRY; INNATE IMMUNITY; KNOCKOUT MOUSE; LYMPHOCYTOTOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; VIRUS MYOCARDITIS; WILD TYPE;

ADOPTIVE TRANSFER; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD1D; APOPTOSIS; CELL COUNT; COXSACKIEVIRUS INFECTIONS; CYSTEINE PROTEINASE INHIBITORS; FORKHEAD TRANSCRIPTION FACTORS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDITIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 77956309537     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2010.03292.x     Document Type: Article

References (46)

1. Woodruff J. Viral myocarditis. Am J Pathol 1980 101 : 425 483.
2. Bowles NE, Ni J, Kearney DL et al. Detection of viruses in myocardial tissues by polymerase chain reaction. Evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol 2003 42 : 466 472.
3. Kandolf R, Sauter M, Aepinus C, Schnorr JJ, Selinka HC, Klingel K. Mechanisms and consequences of enterovirus persistence in cardiac myocytes and cells of the immune system. Virus Res 1999 62 : 149 158.
4. Freeman G, Colston J, Zabalgoitia M, Chandrasekar B. Contractile depression and expression of proinflammatory cytokines and iNOS in viral myocarditis. Am J Physiol 1998 274 (1p+2 H249 58.
5. Badorff C, Lee GH, Lamphear BJ, Martone ME, Campbell KP, Rhoads RE, Knowlton KU. Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nat Med 1999 5 : 320 326.
6. Fairweather D, Kaya Z, Shellam GR, Lawson CM, Rose NR. From infection to autoimmunity. J Autoimmun 2001 16 : 175 186.
7. Huber S, Lodge P. Coxsackievirus B3 myocarditis in Balb/c mice: evidence for autoimmunity to myocyte antigens. Am J Path 1984 116 : 21.
8. Huber SA. Autoimmunity in coxsackievirus B3 induced myocarditis. Autoimmunity 2006 39 : 55 61.
9. Huber SA, Sartini D, Exley M. Vgamma4(+) T cells promote autoimmune CD8(+) cytolytic T-lymphocyte activation in coxsackievirus B3-induced myocarditis in mice: role for CD4(+) Th1 cells. J Virol 2002 76 : 10785 10790.
10. Huber S, Song WC, Sartini D. Decay-accelerating factor (CD55) promotes CD1d expression and Vgamma4+ T-cell activation in coxsackievirus B3-induced myocarditis. Viral Immunol 2006 19 : 156 166.
11. Canchis PW, Bhan AK, Landau SB, Yang L, Balk SP, Blumberg RS. Tissue distribution of the non-polymorphic major histocompatibility complex class I-like molecule, CD1d. Immunology 1993 80 : 561 565.
12. Park SH, Roark JH, Bendelac A. Tissue-specific recognition of mouse CD1 molecules. J Immunol 1998 160 : 3128 3134.
13. Miyagi T, Takehara T, Tatsumi T et al. CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver. Int J Cancer 2003 106 : 81 9.
14. Lee PT, Benlagha K, Teyton L, Bendelac A. Distinct functional lineages of human V(alpha)24 natural killer T cells. J Exp Med 2002 195 : 637 641.
15. Kronenberg M, Gapin L. The unconventional lifestyle of NKT cells. Nat Rev Immunol 2002 2 : 557 568.
16. Cardell SL. The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice. Clin Exp Immunol 2006 143 : 194 202.
17. Behar SM, Podrebarac TA, Roy CJ, Wang CR, Brenner MB. Diverse TCRs recognize murine CD1. J Immunol 1999 162 : 161 167.
18. Olson CM Jr., Bates TC, Izadi H, Radolf JD, Huber SA, Boyson JE, Anguita J. Local production of IFN-gamma by invariant NKT cells modulates acute Lyme carditis. J Immunol 2009 182 : 3728 3734.
19. Bendelac A, Rivera MN, Park SH, Roark JH. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu Rev Immunol 1997 15 : 535 562.
20. Carnaud C, Lee D, Donnars O, Park SH, Beavis A, Koezuka Y, Bendelac A. Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J Immunol 1999 163 : 4647 4650.
21. Exley MA, He Q, Cheng O, Wang RJ, Cheney CP, Balk SP, Koziel MJ. Cutting edge: compartmentalization of Th1-like noninvariant CD1d-reactive T cells in hepatitis C virus-infected liver. J Immunol 2002 168 : 1519 1523.
22. Faveeuw C, Angeli V, Fontaine J et al. Antigen presentation by CD1d contributes to the amplification of Th2 responses to Schistosoma mansoni glycoconjugates in mice. J Immunol 2002 169 : 906 912.
23. Fiedler T, Walter W, Reichert TE, Maeurer MJ. Regulation of CD1d expression by murine tumor cells: escape from immunosurveillance or alternate target molecules? Int J Cancer 2002 98 : 389 397.
24. Sonoda KH, Exley M, Snapper S, Balk SP, Stein-Streilein J. CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site. J Exp Med 1999 190 : 1215 1226.
25. Li W, Ji F, Zhang Y, Wang Y, Yang N, Ge H, Wang F. Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in prevention of autoimmune diabetes in non-obese diabetic mice treated with alpha-galactosylceramide. Acta Biochim Biophys Sin (Shanghai) 2008 40 : 381 390.
26. Huber S, Sartini D, Exley M. Role of CD1d in coxsackievirus B3-induced myocarditis. J Immunol 2003 170 : 3147 3153.
27. Faure F, Jitsukawa S, Miossec C, Hercend T. CD1c as a target recognition structure for human T lymphocytes: analysis with peripheral blood gamma/delta cells. Eur J Immunol 1990 20 : 703 706.
28. Leslie DS, Vincent MS, Spada FM, Das H, Sugita M, Morita CT, Brenner MB. CD1-mediated gamma/delta T cell maturation of dendritic cells. J Exp Med 2002 196 : 1575 1584.
29. Huber SA, Feldman AM, Sartini D. Coxsackievirus B3 induces T regulatory cells, which inhibit cardiomyopathy in tumor necrosis factor-alpha transgenic mice. Circ Res 2006 99 : 1109 1116.
30. Huber SA. Depletion of gammadelta+ T cells increases CD4+ FoxP3 (T regulatory) cell response in coxsackievirus B3-induced myocarditis. Immunology 2009 127 : 567 576.
31. Knowlton KU, Jeon ES, Berkley N, Wessely R, Huber S. A mutation in the puff region of VP2 attenuates the myocarditic phenotype of an infectious cDNA of the Woodruff variant of coxsackievirus B3. J Virol 1996 70 : 7811 7818.
32. Van Houten N, Bouchard P, Moraska A, Huber S. Selection of an attenuated coxsackievirus B3 variant using a monoclonal antibody reactive to myocyte antigen. J Virol 1991 65 : 1286 1290.
33. Huber S, Graveline D, Born W, O'Brien R. Cytokine production by Vgamma+ T cell subsets is an important factor determining Cd4+ Th cell phenotype and susceptibility of BALB/c mice to coxsackievirus B3-induced myocarditis. J Virol 2001 75 : 5860 5868.
34. Miko E, Szereday L, Barakonyi A, Jarkovich A, Varga P, Szekeres-Bartho J. Immunoactivation in preeclampsia: Vdelta2+ and regulatory T cells during the inflammatory stage of disease. J Reprod Immunol 2009 80 : 100 108.
35. Malone F, Carper K, Reyes J, Li W. gammadeltaT cells are involved in liver transplant tolerance. Transplant Proc 2009 41 : 233 235.
36. Gong G, Shao L, Wang Y et al. Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Blood 2009 113 : 837 845.
37. Hahn YS, Ji XY, Woo SI et al. Vgamma1+ gammadelta T cells reduce IL-10-producing CD4+CD25+ T cells in the lung of ovalbumin-sensitized and challenged mice. Immunol Lett 2008 121 : 87 92.
38. Pabst C, Schirutschke H, Ehninger G, Bornhauser M, Platzbecker U. The graft content of donor T cells expressing gamma delta TCR+ and CD4+foxp3+ predicts the risk of acute graft versus host disease after transplantation of allogeneic peripheral blood stem cells from unrelated donors. Clin Cancer Res 2007 13 : 2916 2922.
39. Zhou J, Appleton SE, Stadnyk A, Lee TD, Nashan BA. CD8+ gammadelta T regulatory cells mediate kidney allograft prolongation after oral exposure to alloantigen. Transpl Int 2008 21 : 679 687.
40. Martino A, Poccia F. Gamma delta T cells and dendritic cells: close partners and biological adjuvants for new therapies. Curr Mol Med 2007 7 : 658 673.
41. Fu BM, He XS, Yu S, Hu AB, Ma Y, Wu LW, Tam NL, Huang JF. Tolerogenic semimature dendritic cells induce effector T-cell hyporesponsiveness by the activation of antigen-specific CD4+ CD25+ T-regulatory cells. Exp Clin Transplant 2009 7 : 149 156.
42. Chen J, Schmitt A, Giannopoulos K, Chen B, Rojewski M, Dohner H, Bunjes D, Schmitt M. Imatinib impairs the proliferation and function of CD4+CD25+ regulatory T cells in a dose-dependent manner. Int J Oncol 2007 31 : 1133 1139.
43. Huber S, Graveline D, Newell M, Born W, O'Brien R. Vgamma1+ T cells suppress and Vgamma4+ T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice. J Immunol 2000 165 : 4174 4181.
44. Sonoda KH, Faunce DE, Taniguchi M, Exley M, Balk S, Stein-Streilein J. NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance. J Immunol 2001 166 : 42 50.
45. Stein-Streilein J, Sonoda KH, Faunce D, Zhang-Hoover J. Regulation of adaptive immune responses by innate cells expressing NK markers and antigen-transporting macrophages. J Leukoc Biol 2000 67 : 488 494.
46. Uemura Y, Liu TY, Narita Y et al. Cytokine-dependent modification of IL-12p70 and IL-23 balance in dendritic cells by ligand activation of Valpha24 invariant NKT cells. J Immunol 2009 183 : 201 208.