-
1
-
-
0030840420
-
Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study
-
Meigs JB, D'Agostino Sr RB, Wilson PW, Cupples LA, Nathan DM, Singer DE 1997 Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes 46:1594-1600
-
(1997)
Diabetes
, vol.46
, pp. 1594-1600
-
-
Meigs, J.B.1
D'Agostino Sr, R.B.2
Wilson, P.W.3
Cupples, L.A.4
Nathan, D.M.5
Singer, D.E.6
-
2
-
-
0025780331
-
Hyperinsulinaemia: The key feature of a cardiovascular and metabolic syndrome
-
Ferrannini E, Haffner SM, Mitchell BD, Stern MP 1991 Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 34:416-422
-
(1991)
Diabetologia
, vol.34
, pp. 416-422
-
-
Ferrannini, E.1
Haffner, S.M.2
Mitchell, B.D.3
Stern, M.P.4
-
3
-
-
0018612858
-
An investigation of coronary heart disease in families: The Framingham Offspring Study
-
Kannel WB, Feinleib M, McNamara JR, Garrison RJ, Castelli WP 1979 An investigation of coronary heart disease in families: the Framingham Offspring Study. Am J Epidemiol 110:281-290
-
(1979)
Am J Epidemiol
, vol.110
, pp. 281-290
-
-
Kannel, W.B.1
Feinleib, M.2
McNamara, J.R.3
Garrison, R.J.4
Castelli, W.P.5
-
4
-
-
0024593457
-
Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance
-
Zavaroni I, Bonora E, Pagliara M, Dall'Aglio E, Luchetti L, Buonanno G, Bonati PA, Bergonzani M, Gnudi L, Passeri M, Reaven GM 1989 Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance. N Engl J Med 320:502-506
-
(1989)
N Engl J Med
, vol.320
, pp. 502-506
-
-
Zavaroni, I.1
Bonora, E.2
Pagliara, M.3
Dall'Aglio, E.4
Luchetti, L.5
Buonanno, G.6
Bonati, P.A.7
Bergonzani, M.8
Gnudi, L.9
Passeri, M.10
Reaven, G.M.11
-
5
-
-
0024160877
-
Role of insulin resistance in human disease
-
Reaven GM 1988 Role of insulin resistance in human disease. Diabetes 37: 1595-1607
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
6
-
-
0027275518
-
Changes in insulin and lipid metabolism in males with asymptomatic hyperuricaemia
-
Zavaroni I, Mazza S, Fantuzzi M, Dall'Aglio E, Bonora E, Delsignore R, Passeri M, Reaven GM 1993 Changes in insulin and lipid metabolism in males with asymptomatic hyperuricaemia. J Intern Med 234:25-30
-
(1993)
J Intern Med
, vol.234
, pp. 25-30
-
-
Zavaroni, I.1
Mazza, S.2
Fantuzzi, M.3
Dall'Aglio, E.4
Bonora, E.5
Delsignore, R.6
Passeri, M.7
Reaven, G.M.8
-
7
-
-
0027183606
-
Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles
-
Reaven GM, Chen YD, Jeppesen J, Maheux P, Krauss RM 1993 Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. J Clin Invest 92:141-146
-
(1993)
J Clin Invest
, vol.92
, pp. 141-146
-
-
Reaven, G.M.1
Chen, Y.D.2
Jeppesen, J.3
Maheux, P.4
Krauss, R.M.5
-
8
-
-
2142643265
-
Insulin resistance syndrome and the prothrombotic state: A Framingham perspective
-
Wilson PW 2003 Insulin resistance syndrome and the prothrombotic state: a Framingham perspective. Endocr Pract 9(Suppl 2):50-52
-
(2003)
Endocr Pract
, vol.9
, Issue.SUPPL. 2
, pp. 50-52
-
-
Wilson, P.W.1
-
9
-
-
16644385307
-
The relationship between hyperinsulinemia, hypertension and progressive renal disease
-
El-Atat FA, Stas SN, McFarlane SI, Sowers JR 2004 The relationship between hyperinsulinemia, hypertension and progressive renal disease. J Am Soc Nephrol 15:2816-2827
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2816-2827
-
-
El-Atat, F.A.1
Stas, S.N.2
McFarlane, S.I.3
Sowers, J.R.4
-
11
-
-
25644448266
-
Fat in the liver and insulin resistance
-
Yki-Järvinen H 2005 Fat in the liver and insulin resistance. Ann Med 37:347-356
-
(2005)
Ann Med
, vol.37
, pp. 347-356
-
-
Yki-Järvinen, H.1
-
12
-
-
27944453528
-
Epicardial adipose tissue: Anatomic, biomolecular and clinical relationships with the heart
-
Iacobellis G, Corradi D, Sharma AM 2005 Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart. Nat Clin Pract Cardiovasc Med 2:536-543
-
(2005)
Nat Clin Pract Cardiovasc Med
, vol.2
, pp. 536-543
-
-
Iacobellis, G.1
Corradi, D.2
Sharma, A.M.3
-
13
-
-
31744443753
-
Is visceral obesity the cause of the metabolic syndrome?
-
Despres JP 2006 Is visceral obesity the cause of the metabolic syndrome? Ann Med 38:52-63
-
(2006)
Ann Med
, vol.38
, pp. 52-63
-
-
Despres, J.P.1
-
14
-
-
0034504237
-
Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
-
Wajchenberg BL 2000 Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 21:698-738
-
(2000)
Endocr Rev
, vol.21
, pp. 698-738
-
-
Wajchenberg, B.L.1
-
15
-
-
24144493627
-
Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: A positron-emitting tomography study
-
Virtanen KA, Iozzo P, Hallsten K, Huupponen R, Parkkola R, Janatuinen T, Lonnqvist F, Viljanen T, Ronnemaa T, Lonnroth P, Knuuti J, Ferrannini E, Nuutila P 2005 Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study. Diabetes 54:2720-2726
-
(2005)
Diabetes
, vol.54
, pp. 2720-2726
-
-
Virtanen, K.A.1
Iozzo, P.2
Hallsten, K.3
Huupponen, R.4
Parkkola, R.5
Janatuinen, T.6
Lonnqvist, F.7
Viljanen, T.8
Ronnemaa, T.9
Lonnroth, P.10
Knuuti, J.11
Ferrannini, E.12
Nuutila, P.13
-
16
-
-
29244465509
-
Human fat cell lipolysis: Biochemistry, regulation and clinical role
-
Arner P 2005 Human fat cell lipolysis: biochemistry, regulation and clinical role. Best Pract Res Clin Endocrinol Metab 19:471-482
-
(2005)
Best Pract Res Clin Endocrinol Metab
, vol.19
, pp. 471-482
-
-
Arner, P.1
-
17
-
-
30544439060
-
Therapy insight: Adipocytokines in metabolic syndrome and related cardiovascular disease
-
Matsuzawa Y 2006 Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat Clin Pract Cardiovasc Med 3:35-42
-
(2006)
Nat Clin Pract Cardiovasc Med
, vol.3
, pp. 35-42
-
-
Matsuzawa, Y.1
-
18
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
Berg AH, Scherer PE 2005 Adipose tissue, inflammation, and cardiovascular disease. Circ Res 96:939-949
-
(2005)
Circ Res
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
19
-
-
17844363297
-
The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans
-
Andrew R, Westerbacka J, Wahren J, Yki-Jarvinen H, Walker BR 2005 The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans. Diabetes 54:1364-1370
-
(2005)
Diabetes
, vol.54
, pp. 1364-1370
-
-
Andrew, R.1
Westerbacka, J.2
Wahren, J.3
Yki-Jarvinen, H.4
Walker, B.R.5
-
20
-
-
3242795814
-
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome
-
Carr DB, Utzschneider KM, Hull RL, Kodama K, Retzlaff BM, Brunzell JD, Shofer JB, Fish BE, Knopp RH, Kahn SE 2004 Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53:2087-2094
-
(2004)
Diabetes
, vol.53
, pp. 2087-2094
-
-
Carr, D.B.1
Utzschneider, K.M.2
Hull, R.L.3
Kodama, K.4
Retzlaff, B.M.5
Brunzell, J.D.6
Shofer, J.B.7
Fish, B.E.8
Knopp, R.H.9
Kahn, S.E.10
-
21
-
-
1842844418
-
-
Hills SA, Balkau B, Coppack SW, Dekker JM, Mari A, Natali A, Walker M, Ferrannini E, EGIR-RISC Study Group 2004 The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives. Diabetologia 47:566-570
-
Hills SA, Balkau B, Coppack SW, Dekker JM, Mari A, Natali A, Walker M, Ferrannini E, EGIR-RISC Study Group 2004 The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives. Diabetologia 47:566-570
-
-
-
-
22
-
-
0027499784
-
Enzyme immunoassay for intact human insulin in serum or plasma
-
Andersen L, Dinesen B, Jørgensen P, Poulsen F, Røder M 1993 Enzyme immunoassay for intact human insulin in serum or plasma. Clin Chem 39: 578-582
-
(1993)
Clin Chem
, vol.39
, pp. 578-582
-
-
Andersen, L.1
Dinesen, B.2
Jørgensen, P.3
Poulsen, F.4
Røder, M.5
-
23
-
-
17144469684
-
-
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus 2000 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 23(Suppl 1):S4-S19
-
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus 2000 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 23(Suppl 1):S4-S19
-
-
-
-
24
-
-
0031846461
-
How to measure insulin sensitivity
-
Ferrannini E, Mari A 1998 How to measure insulin sensitivity. J Hypertens 16:895-906
-
(1998)
J Hypertens
, vol.16
, pp. 895-906
-
-
Ferrannini, E.1
Mari, A.2
-
25
-
-
0030884698
-
Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR)
-
Ferrannini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G 1997 Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest 100:1166-1173
-
(1997)
J Clin Invest
, vol.100
, pp. 1166-1173
-
-
Ferrannini, E.1
Natali, A.2
Bell, P.3
Cavallo-Perin, P.4
Lalic, N.5
Mingrone, G.6
-
26
-
-
0037392419
-
-
Stolk RP, Meijer R, Mali WP, Grobbee DE, der Graaf Y, Secondary Manifestations of Arterial Disease Study Group 2003 Ultrasound measurements of intraabdominal fat estimate the metabolic syndrome better than do measurements of waist circumference. Am J Clin Nutr 77:857-860
-
Stolk RP, Meijer R, Mali WP, Grobbee DE, der Graaf Y, Secondary Manifestations of Arterial Disease Study Group 2003 Ultrasound measurements of intraabdominal fat estimate the metabolic syndrome better than do measurements of waist circumference. Am J Clin Nutr 77:857-860
-
-
-
-
27
-
-
2942598368
-
Beta cell function and its relation to insulin action in humans: A critical appraisal
-
Ferrannini E, Mari A 2004 Beta cell function and its relation to insulin action in humans: a critical appraisal. Diabetologia 47:943-956
-
(2004)
Diabetologia
, vol.47
, pp. 943-956
-
-
Ferrannini, E.1
Mari, A.2
-
28
-
-
0027762766
-
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians
-
Lillioja S, Mott DM, Spraul M, Ferraro R, Foley JE, Ravussin E, Knowler WC, Bennett PH, Bogardus C 1993 Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med 329:1988-1992
-
(1993)
N Engl J Med
, vol.329
, pp. 1988-1992
-
-
Lillioja, S.1
Mott, D.M.2
Spraul, M.3
Ferraro, R.4
Foley, J.E.5
Ravussin, E.6
Knowler, W.C.7
Bennett, P.H.8
Bogardus, C.9
-
29
-
-
0026021161
-
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo RA, Ferrannini E 1991 Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
30
-
-
28444472424
-
Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of hyperglycaemia in non-diabetic subjects
-
Walker M, Mari A, Jayapaul MK, Bennett SM, Ferrannini E 2005 Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of hyperglycaemia in non-diabetic subjects. Diabetologia 48:2470-2476
-
(2005)
Diabetologia
, vol.48
, pp. 2470-2476
-
-
Walker, M.1
Mari, A.2
Jayapaul, M.K.3
Bennett, S.M.4
Ferrannini, E.5
-
31
-
-
18644370344
-
Type 2 diabetes as a lipid disorder
-
Taskinen MR 2005 Type 2 diabetes as a lipid disorder. Curr Mol Med 5:297-308
-
(2005)
Curr Mol Med
, vol.5
, pp. 297-308
-
-
Taskinen, M.R.1
-
32
-
-
0021265240
-
Effect of in vivo plasma insulin levels on the relationship between perfusate free fatty acid concentration and triglyceride secretion by perfused rat livers
-
Reaven GM, Mondon CE 1984 Effect of in vivo plasma insulin levels on the relationship between perfusate free fatty acid concentration and triglyceride secretion by perfused rat livers. Horm Metab Res 16:230-232
-
(1984)
Horm Metab Res
, vol.16
, pp. 230-232
-
-
Reaven, G.M.1
Mondon, C.E.2
-
33
-
-
0028147131
-
Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man
-
Del Prato S, Leonetti F, Simonson DC, Sheehan P, Matsuda M, DeFronzo RA 1994 Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia 37:1025-1035
-
(1994)
Diabetologia
, vol.37
, pp. 1025-1035
-
-
Del Prato, S.1
Leonetti, F.2
Simonson, D.C.3
Sheehan, P.4
Matsuda, M.5
DeFronzo, R.A.6
-
34
-
-
12144279575
-
Molecular evidence supporting the portal theory: A causative link between visceral adiposity and hepatic insulin resistance
-
Kabir M, Catalano KJ, Ananthnarayan S, Kim SP, Van Citters GW, Dea MK, Bergman RN 2005 Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. Am J Physiol Endocrinol Metab 288:E454-E461
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Kabir, M.1
Catalano, K.J.2
Ananthnarayan, S.3
Kim, S.P.4
Van Citters, G.W.5
Dea, M.K.6
Bergman, R.N.7
-
35
-
-
0035342367
-
Do stress reactions cause abdominal obesity and comorbidities?
-
Bjorntorp P 2001 Do stress reactions cause abdominal obesity and comorbidities? Obes Rev 2:73-86
-
(2001)
Obes Rev
, vol.2
, pp. 73-86
-
-
Bjorntorp, P.1
-
36
-
-
0019483909
-
Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man
-
Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L 1981 Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 30:219-225
-
(1981)
Diabetes
, vol.30
, pp. 219-225
-
-
Rowe, J.W.1
Young, J.B.2
Minaker, K.L.3
Stevens, A.L.4
Pallotta, J.5
Landsberg, L.6
-
37
-
-
0037409237
-
The adipose-tissue renin-angiotensin- aldosterone system: Role in the metabolic syndrome?
-
Engeli S, Schling P, Gorzelniak K, Boscmann M, Janke J, Ailhaud G, Teboul M, Massiera F, Sharma AM 2003 The adipose-tissue renin-angiotensin- aldosterone system: role in the metabolic syndrome? Int J Biochem Cell Biol 35: 807-825
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 807-825
-
-
Engeli, S.1
Schling, P.2
Gorzelniak, K.3
Boscmann, M.4
Janke, J.5
Ailhaud, G.6
Teboul, M.7
Massiera, F.8
Sharma, A.M.9
-
38
-
-
0036326047
-
Factor analysis of metabolic syndrome using directly measured insulin sensitivity. The Insulin Resistance Atherosclerosis Study
-
Hanley AJ, Karter AJ, Festa A, D'Agostino Jr RB, Wagenknecht LE, Savage PJ, Tracy RP, Saad MF, Haffner S 2004 Factor analysis of metabolic syndrome using directly measured insulin sensitivity. The Insulin Resistance Atherosclerosis Study. Diabetes 51:2642-2647
-
(2004)
Diabetes
, vol.51
, pp. 2642-2647
-
-
Hanley, A.J.1
Karter, A.J.2
Festa, A.3
D'Agostino Jr, R.B.4
Wagenknecht, L.E.5
Savage, P.J.6
Tracy, R.P.7
Saad, M.F.8
Haffner, S.9
-
39
-
-
33644873948
-
A single factor underlies the metabolic syndrome: A confirmatory factor analysis
-
Pladevall M, Singal B, Williams LK, Brotons C, Guyer H, Sadurni J, Falces C, Serrano-Rios M, Gabriel R, Shaw JE, Zimmet PZ, Haffner S 2006 A single factor underlies the metabolic syndrome: a confirmatory factor analysis. Diabetes Care 29:113-122
-
(2006)
Diabetes Care
, vol.29
, pp. 113-122
-
-
Pladevall, M.1
Singal, B.2
Williams, L.K.3
Brotons, C.4
Guyer, H.5
Sadurni, J.6
Falces, C.7
Serrano-Rios, M.8
Gabriel, R.9
Shaw, J.E.10
Zimmet, P.Z.11
Haffner, S.12
-
40
-
-
3142783848
-
Mis)use of factor analysis in the study of insulin resistance syndrome
-
Lawlor DA, Ebrahim S, May M, Davey Smith G 2004 (Mis)use of factor analysis in the study of insulin resistance syndrome. Am J Epidemiol 159:1013-1018
-
(2004)
Am J Epidemiol
, vol.159
, pp. 1013-1018
-
-
Lawlor, D.A.1
Ebrahim, S.2
May, M.3
Davey Smith, G.4
|