메뉴 건너뛰기




Volumn 23, Issue 9, 2010, Pages 1279-1288

Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; PROTEIN MDM2;

EID: 77956275003     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.124     Document Type: Article
Times cited : (157)

References (35)
  • 1
    • 44949151698 scopus 로고    scopus 로고
    • A comparison of intramedullary and juxtacortical low-grade osteogenic sarcoma
    • Schwab JH, Antonescu CR, Athanasian EA, et al. A comparison of intramedullary and juxtacortical low-grade osteogenic sarcoma. Clin Orthop Relat Res 2008;466:1318-1322.
    • (2008) Clin Orthop Relat Res , vol.466 , pp. 1318-1322
    • Schwab, J.H.1    Antonescu, C.R.2    Athanasian, E.A.3
  • 6
    • 0028384491 scopus 로고
    • Parosteal osteosarcoma. A clinicopathological study
    • Okada K, Frassica FJ, Sim FH, et al. Parosteal osteosarcoma. A clinicopathological study. J Bone Joint Surg Am 1994;76:366-378.
    • (1994) J Bone Joint Surg Am , vol.76 , pp. 366-378
    • Okada, K.1    Frassica, F.J.2    Sim, F.H.3
  • 7
    • 0025265131 scopus 로고
    • Low-grade intraosseous osteosarcoma
    • Kurt AM, Unni KK, McLeod RA, et al. Low-grade intraosseous osteosarcoma. Cancer 1990;65:1418-1428.
    • (1990) Cancer , vol.65 , pp. 1418-1428
    • Kurt, A.M.1    Unni, K.K.2    McLeod, R.A.3
  • 8
    • 0029926512 scopus 로고    scopus 로고
    • Conventional and dedifferentiated parosteal osteosarcoma. Diagnosis, treatment, and outcome
    • Sheth DS, Yasko AW, Raymond AK, et al. Conventional and dedifferentiated parosteal osteosarcoma. Diagnosis, treatment, and outcome. Cancer 1996;78:2136-2145.
    • (1996) Cancer , vol.78 , pp. 2136-2145
    • Sheth, D.S.1    Yasko, A.W.2    Raymond, A.K.3
  • 9
    • 0026625580 scopus 로고
    • Supernumerary ring chromosomes in five bone and soft tissue tumors of low or borderline malignancy
    • Orndal C, Mandahl N, Rydholm A, et al. Supernumerary ring chromosomes in five bone and soft tissue tumors of low or borderline malignancy. Cancer Genet Cytogenet 1992;60:170-175.
    • (1992) Cancer Genet Cytogenet , vol.60 , pp. 170-175
    • Orndal, C.1    Mandahl, N.2    Rydholm, A.3
  • 10
    • 0026705857 scopus 로고
    • Ring chromosome in parosteal osteosarcoma. Clinical and diagnostic significance
    • Sinovic JF, Bridge JA, Neff JR. Ring chromosome in parosteal osteosarcoma. Clinical and diagnostic significance. Cancer Genet Cytogenet 1992;62:50-52.
    • (1992) Cancer Genet Cytogenet , vol.62 , pp. 50-52
    • Sinovic, J.F.1    Bridge, J.A.2    Neff, J.R.3
  • 11
    • 18244383816 scopus 로고    scopus 로고
    • Differentially amplified chromosome 12 sequences in low-and high-grade osteosarcoma
    • Gisselsson D, Palsson E, Hoglund M, et al. Differentially amplified chromosome 12 sequences in low-and high-grade osteosarcoma. Genes Chromosomes Cancer 2002;33:133-140.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 133-140
    • Gisselsson, D.1    Palsson, E.2    Hoglund, M.3
  • 12
    • 0029937660 scopus 로고    scopus 로고
    • Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: A combined cytogenetic and comparative genomic hybridization study
    • Szymanska J, Mandahl N, Mertens F, et al. Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: a combined cytogenetic and comparative genomic hybridization study. Genes Chromosomes Cancer 1996;16:31-34.
    • (1996) Genes Chromosomes Cancer , vol.16 , pp. 31-34
    • Szymanska, J.1    Mandahl, N.2    Mertens, F.3
  • 13
    • 0028905350 scopus 로고
    • Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization
    • Tarkkanen M, Karhu R, Kallioniemi A, et al. Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization. Cancer Res 1995; 55:1334-1338.
    • (1995) Cancer Res , vol.55 , pp. 1334-1338
    • Tarkkanen, M.1    Karhu, R.2    Kallioniemi, A.3
  • 14
    • 0344973662 scopus 로고    scopus 로고
    • Comparative genomic hybridization of low-grade central osteosarcoma
    • Tarkkanen M, Bohling T, Gamberi G, et al. Comparative genomic hybridization of low-grade central osteosarcoma. Mod Pathol 1998;11:421-426.
    • (1998) Mod Pathol , vol.11 , pp. 421-426
    • Tarkkanen, M.1    Bohling, T.2    Gamberi, G.3
  • 15
  • 16
    • 0033590604 scopus 로고    scopus 로고
    • Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas
    • Wunder JS, Eppert K, Burrow SR, et al. Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas. Oncogene 1999;18:783-788.
    • (1999) Oncogene , vol.18 , pp. 783-788
    • Wunder, J.S.1    Eppert, K.2    Burrow, S.R.3
  • 17
    • 0030250837 scopus 로고    scopus 로고
    • SAS is amplified predominantly in surface osteosarcoma
    • Noble-Topham SE, Burrow SR, Eppert K, et al. SAS is amplified predominantly in surface osteosarcoma. J Orthop Res 1996;14:700-705.
    • (1996) J Orthop Res , vol.14 , pp. 700-705
    • Noble-Topham, S.E.1    Burrow, S.R.2    Eppert, K.3
  • 18
    • 0033579870 scopus 로고    scopus 로고
    • CDK4 gene amplification in osteosarcoma: Reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons
    • Wei G, Lonardo F, Ueda T, et al. CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons. Int J Cancer 1999;80:199-204.
    • (1999) Int J Cancer , vol.80 , pp. 199-204
    • Wei, G.1    Lonardo, F.2    Ueda, T.3
  • 19
    • 3142697631 scopus 로고    scopus 로고
    • Molecular analysis of p53, MDM2 and H-ras genes in low-grade central osteosarcoma
    • Park HR, Jung WW, Bertoni F, et al. Molecular analysis of p53, MDM2 and H-ras genes in low-grade central osteosarcoma. Pathol Res Pract 2004;200: 439-445.
    • (2004) Pathol Res Pract , vol.200 , pp. 439-445
    • Park, H.R.1    Jung, W.W.2    Bertoni, F.3
  • 20
    • 2442701607 scopus 로고    scopus 로고
    • Deregulation of the G1 to S-phase cell cycle checkpoint is involved in the pathogenesis of human osteosarcoma
    • Lopez-Guerrero JA, Lopez-Gines C, Pellin A, et al. Deregulation of the G1 to S-phase cell cycle checkpoint is involved in the pathogenesis of human osteosarcoma. Diagn Mol Pathol 2004;13:81-91.
    • (2004) Diagn Mol Pathol , vol.13 , pp. 81-91
    • Lopez-Guerrero, J.A.1    Lopez-Gines, C.2    Pellin, A.3
  • 21
    • 0027533193 scopus 로고
    • Osteosarcoma Low-grade intraosseous-type osteosarcoma, histologically resembling parosteal osteosarcoma, fibrous dysplasia, and desmoplastic fibroma
    • Bertoni F, Bacchini P, Fabbri N, et al. Osteosarcoma. Low-grade intraosseous-type osteosarcoma, histologically resembling parosteal osteosarcoma, fibrous dysplasia, and desmoplastic fibroma. Cancer 1993;71: 338-345.
    • (1993) Cancer , vol.71 , pp. 338-345
    • Bertoni, F.1    Bacchini, P.2    Fabbri, N.3
  • 22
    • 0031837893 scopus 로고    scopus 로고
    • Osteochondroma like parosteal osteosarcoma: A report of six cases of a new entity
    • Lin J, Yao L, Mirra JM, et al. Osteochondroma like parosteal osteosarcoma: a report of six cases of a new entity. AJR Am J Roentgenol 1998;170:1571-1577.
    • (1998) AJR Am J Roentgenol , vol.170 , pp. 1571-1577
    • Lin, J.1    Yao, L.2    Mirra, J.M.3
  • 23
    • 0027997523 scopus 로고
    • Exophytic variant of fibrous dysplasia (fibrous dysplasia protuberans)
    • Dorfman HD, Ishida T, Tsuneyoshi M. Exophytic variant of fibrous dysplasia (fibrous dysplasia protuberans). Hum Pathol 1994;25:1234-1237.
    • (1994) Hum Pathol , vol.25 , pp. 1234-1237
    • Dorfman, H.D.1    Ishida, T.2    Tsuneyoshi, M.3
  • 24
    • 0027158691 scopus 로고
    • Bizarre parosteal osteochondromatous proliferation of bone (Noras lesion)
    • Meneses MF, Unni KK, Swee RG. Bizarre parosteal osteochondromatous proliferation of bone (Noras lesion). Am J Surg Pathol 1993;17:691-697.
    • (1993) Am J Surg Pathol , vol.17 , pp. 691-697
    • Meneses, M.F.1    Unni, K.K.2    Swee, R.G.3
  • 25
    • 0042745585 scopus 로고    scopus 로고
    • Myositis ossificans and fibroosseous pseudotumor of digits: A clinicopathological review of 64 cases with emphasis on diagnostic pitfalls
    • de Silva MV, Reid R. Myositis ossificans and fibroosseous pseudotumor of digits: a clinicopathological review of 64 cases with emphasis on diagnostic pitfalls. Int J Surg Pathol 2003;11:187-195.
    • (2003) Int J Surg Pathol , vol.11 , pp. 187-195
    • De Silva, M.V.1    Reid, R.2
  • 26
    • 7744233491 scopus 로고    scopus 로고
    • Pseudoanaplastic tumors of bone
    • Bahk WJ, Mirra JM. Pseudoanaplastic tumors of bone. Skeletal Radiol 2004;33:641-648.
    • (2004) Skeletal Radiol , vol.33 , pp. 641-648
    • Bahk, W.J.1    Mirra, J.M.2
  • 27
    • 0033946151 scopus 로고    scopus 로고
    • Low-grade intraosseous osteosarcoma in northern Japan: Advantage of AgNOR and MIB-1 staining in differential diagnosis
    • Okada K, Nishida J, Morita T, et al. Low-grade intraosseous osteosarcoma in northern Japan: advantage of AgNOR and MIB-1 staining in differential diagnosis. Hum Pathol 2000;31:633-639.
    • (2000) Hum Pathol , vol.31 , pp. 633-639
    • Okada, K.1    Nishida, J.2    Morita, T.3
  • 28
    • 0034742033 scopus 로고    scopus 로고
    • Gsalpha gene mutations in monostotic fibrous dysplasia of bone and fibrous dysplasia-like low-grade central osteosarcoma
    • Pollandt K, Engels C, Kaiser E, et al. Gsalpha gene mutations in monostotic fibrous dysplasia of bone and fibrous dysplasia-like low-grade central osteosarcoma. Virchows Arch 2001;439:170-175.
    • (2001) Virchows Arch , vol.439 , pp. 170-175
    • Pollandt, K.1    Engels, C.2    Kaiser, E.3
  • 29
    • 0034819270 scopus 로고    scopus 로고
    • Amplification and protein expression of chromosome 12q13-15 genes in osteosarcomas of the jaws
    • Lopes MA, Nikitakis NG, Ord RA, et al. Amplification and protein expression of chromosome 12q13-15 genes in osteosarcomas of the jaws. Oral Oncol 2001;37:566-571.
    • (2001) Oral Oncol , vol.37 , pp. 566-571
    • Lopes, M.A.1    Nikitakis, N.G.2    Ord, R.A.3
  • 30
    • 0032991072 scopus 로고    scopus 로고
    • Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma
    • Ragazzini P, Gamberi G, Benassi MS, et al. Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma. Cancer Detect Prev 1999;23:129-136.
    • (1999) Cancer Detect Prev , vol.23 , pp. 129-136
    • Ragazzini, P.1    Gamberi, G.2    Benassi, M.S.3
  • 32
    • 0021685005 scopus 로고
    • Borderline osteoblastic tumors: Problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma
    • Dorfman HD, Weiss SW. Borderline osteoblastic tumors: problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma. Semin Diagn Pathol 1984;1:215-234.
    • (1984) Semin Diagn Pathol , vol.1 , pp. 215-234
    • Dorfman, H.D.1    Weiss, S.W.2
  • 33
    • 25444518461 scopus 로고    scopus 로고
    • MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: A comparative analysis of 559 soft tissue neoplasms with genetic data
    • Binh MB, Sastre-Garau X, Guillou L, et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol 2005;29:1340-1347.
    • (2005) Am J Surg Pathol , vol.29 , pp. 1340-1347
    • Binh, M.B.1    Sastre-Garau, X.2    Guillou, L.3
  • 34
    • 0034098659 scopus 로고    scopus 로고
    • The expression of MDM2/CDK4 gene product in the differential diagnosis of well differentiated liposarcoma and large deep-seated lipoma
    • Pilotti S, Della Torre G, Mezzelani A, et al. The expression of MDM2/CDK4 gene product in the differential diagnosis of well differentiated liposarcoma and large deep-seated lipoma. Br J Cancer 2000;82:1271-1275.
    • (2000) Br J Cancer , vol.82 , pp. 1271-1275
    • Pilotti, S.1    Della Torre, G.2    Mezzelani, A.3
  • 35
    • 77952087785 scopus 로고    scopus 로고
    • Characterization of the 12q15 MDM2 and 12q13-14 CDK4 amplicons and clinical correlations in osteosarcoma
    • Mejia-Guerrero S, Quejada M, Gokgoz N, et al. Characterization of the 12q15 MDM2 and 12q13-14 CDK4 amplicons and clinical correlations in osteosarcoma. Genes Chromosomes Cancer 2010;49:518-525.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 518-525
    • Mejia-Guerrero, S.1    Quejada, M.2    Gokgoz, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.