Ring Chromosomes in Parosteal Osteosarcoma Contain Sequences from 12q13-15: A Combined Cytogenetic and Comparative Genomic Hybridization Study

Genes Chromosomes and Cancer

Volumn 16, Issue 1, 1996, Pages 31-34

  Szymanska, Jadwiga ^a   Mandahl, Nils ^c   Mertens, Fredrik ^c   Tarkkanen, Maija ^a   Karaharju, Erkki ^b   Knuutila, Sakari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CHROMOSOME 12Q; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; OSTEOSARCOMA; PERIOSTEUM; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BONE NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 12; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; OSTEOSARCOMA; PERIOSTEUM; RING CHROMOSOMES;

EID: 0029937660     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199605)16:1<31::AID-GCC4>3.0.CO;2-4     Document Type: Review

References (23)

1. Dal Cin P, Kools P, Sciot R, De Wever I, Van Damme B, Van de Ven W, Van Den Berghe H (1993) Cytogenetic and fluorescence in situ hybridization investigation of ring chromosomes characterizing a specific pathologic subgroup of adipose tissue tumors. Cancer Genet Cytogenet 68:85-90.
2. Forus A, Flørenes VA, Maelandsmo GM, Meltzer PS, Fodstad Ø, Myklebost O (1993) Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplica do not include MDM2. Cell Growth Differ 4:1065-1070.
3. Forus A, Olde Weghuis D, Smeets D, Fodstad Ø, Myklebost O, van Kessel AG (1995) Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas. Genes Chromosom Cancer 14:15-21.
4. Huvos AG (1979) Bone Tumors. Diagnosis, Treatment and Prognosis. Philadelphia, WB Saunders Co.
5. Kallioniemi O-P, Kallioniemi A, Piper J, Isola J, Waldman FM, Gray JW, Pinkel D (1994) Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosom Cancer 10:231-243.
6. Khatib ZA, Matsushime H, Valentine M, Shapiro DN, Sherr CJ, Look AT (1993) Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res 53:5535-5541.
7. Ladanyi M, Cha C, Lewis R, Jhanwar S, Huvos AG, Healey JH (1993) MDM2 gene amplification in metastatic osteosarcoma. Cancer Res 53:16-18.
8. Lichter P, Cremer T, Borden J, Manuelidis L, Ward DC (1988) Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries. Human Genet 80:224-234.
9. Mandahl N, Heim S, Arheden K, Rydholm A, Willén H, Mitelman F (1988) Rings, dicentrics, and telomeric association in histiocytomas. Cancer Genet Cytogenet 30:23-33.
10. Mandahl N, Höglund M, Mertens F, Rydholm A, Willén H, Brosjö O, Mitelman F (1993) Cytogenetic aberrations in 188 benign and borderline adipose tissue tumors. Genes Chromosom Cancer 9:207-215.
11. Mertens F, Mandahl N, Örndal C, Baldetorp B, Bauer HCF, Rydholm A, Wiebe T, Willén H, Åkerman M, Heim S, Mitelman F (1993) Cytogenetic findings in 33 osteosarcomas. Int J Cancer 55:44-50.
12. Nilbert M, Rydholm A, Willén H, Mitelman F, Mandahl N (1994) MDM2 gene amplification correlates with ring chromosomes in soft tissue tumors. Genes Chromosom Cancer 9:261-265.
13. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B (1992) Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358:80-83.
14. Örndal C, Mandahl N, Rydholm A, Willén H, Brosjö O, Heim S, Mitelman F (1992) Supernumerary ring chromosomes in five bone and soft tissue tumors of low or borderline malignancy. Cancer Genet Cytogenet 60:170-175.
15. Pedeutour F, Suijkerbuijk RF, Van Gaal J, Van de Klundert W, Coindre J-M, Van Haelst A, Collin F, Huffermann K, Turc-Carel C (1993) Chromosome 12 origin in rings and giant markers in well-differentiated liposarcoma. Cancer Genet Cytogenet 66: 133-134.
16. Pedeutour F, Suijkerbuijk RF, Forus A, Van Gaal J, Van de Klundert W, Coindre J-M, Nicolo G, Collin F, Van Haelst U, Huffermann K, Turc-Carel C (1994) Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma. Genes Chromosom Cancer 10:85-94.
17. Pinkel D, Straume T, Gray JW (1986) Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. Proc Natl Acad Sci USA 83:2934-2938.
18. Sinovic JF, Bridge JA, Neff JR (1992) Ring chromosome in parosteal osteosarcoma. Clinical and diagnostic significance. Cancer Genet Cytogenet 62:50-52.
19. Sreekantaiah C, Ladanyi M, Rodrigues E, Chaganti RSK (1994) Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanism. Am J Pathol 144:1121-1134.
20. Suijkerbuijk RF, Olde Weghuis DEM, Van Den Berg M, Pedeutour F, Forus A, Myklebost O, Glier C, Turc-Carel C, van Kessel AG (1994) Comparative genomic hybridization as a tool to define two distinct chromosome 12-derived amplification units in well-differentiated liposarcomas. Genes Chromosom Cancer 9:292-295.
21. Szymanska J, Tarkkanen M, Wiklund T, Virolainen M, Blomqvist C, Asko-Seljavaara S, Tukiainen E, Elomaa I, Knuutila S (1996) Gains and losses of DNA sequences in liposarcomas evaluated by comparative genomic hybridization. Genes Chromosom Cancer 15:89-94.
22. Tarkkanen M, Kaipainen A, Karaharju E, Böhling T, Szymanska J, Heliö H, Kivioja A, Elomaa I, Knuutila S (1993) Cytogenetic study of 249 consecutive patients examined for a bone tumor. Cancer Genet Cytogenet 68:1-21.
23. Tarkkanen M, Karhu R, Kallioniemi A, Elomaa I, Kivioja AH, Nevalainen J, Böhling T, Karaharju E, Hyytinen E, Knuutila S, Kallioniemi O-P (1995) Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization. Cancer Res 55:1334-1338.