-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0023058313
-
Arg-Gly-Asp: A versatile cell recognition signal
-
Ruoslahti E, Pierschbacher MD (1986) Arg-Gly-Asp: a versatile cell recognition signal. Cell 44: 517-518.
-
(1986)
Cell
, vol.44
, pp. 517-518
-
-
Ruoslahti, E.1
Pierschbacher, M.D.2
-
3
-
-
33748922791
-
Cell adhesion molecules for targeted drug delivery
-
Dunehoo AL, Anderson M, Majumdar S, Kobayashi N, Berkland C, et al. (2006) Cell adhesion molecules for targeted drug delivery. J Pharm Sci 95: 1856-1872.
-
(2006)
J Pharm Sci
, vol.95
, pp. 1856-1872
-
-
Dunehoo, A.L.1
Anderson, M.2
Majumdar, S.3
Kobayashi, N.4
Berkland, C.5
-
4
-
-
33748616254
-
Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism
-
Cai W, Chen X (2006) Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism. Anticancer Agents Med Chem 6: 407-428.
-
(2006)
Anticancer Agents Med Chem
, vol.6
, pp. 407-428
-
-
Cai, W.1
Chen, X.2
-
5
-
-
33845329178
-
Signalling via integrins: Implications for cell survival and anticancer strategies
-
Hehlgans S, Haase M, Cordes N (2007) Signalling via integrins: implications for cell survival and anticancer strategies. Biochim Biophys Acta 1775: 163-180.
-
(2007)
Biochim Biophys Acta
, vol.1775
, pp. 163-180
-
-
Hehlgans, S.1
Haase, M.2
Cordes, N.3
-
6
-
-
36148994693
-
The other side of MMPs: Protective roles in tumor progression
-
Martin MD, Matrisian LM (2007) The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev 26: 717-724.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 717-724
-
-
Martin, M.D.1
Matrisian, L.M.2
-
7
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295: 2387-2392.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
8
-
-
33746562929
-
ROCK-and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
-
Wyckoff JB, Pinner SE, Gschmeissner S, Condeelis JS, Sahai E (2006) ROCK-and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol 16: 1515-1523.
-
(2006)
Curr Biol
, vol.16
, pp. 1515-1523
-
-
Wyckoff, J.B.1
Pinner, S.E.2
Gschmeissner, S.3
Condeelis, J.S.4
Sahai, E.5
-
9
-
-
21644479899
-
Tumour invasion and metastasis: Challenges facing drug discovery
-
Elvin P, Garner AP (2005) Tumour invasion and metastasis: challenges facing drug discovery. Curr Opin Pharmacol 5: 374-381.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 374-381
-
-
Elvin, P.1
Garner, A.P.2
-
10
-
-
0035884377
-
Inhibition of tumor cell invasion and angiogenesis by motuporamines
-
Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, et al. (2001) Inhibition of tumor cell invasion and angiogenesis by motuporamines. Cancer Res 61: 6788-6794.
-
(2001)
Cancer Res
, vol.61
, pp. 6788-6794
-
-
Roskelley, C.D.1
Williams, D.E.2
McHardy, L.M.3
Leong, K.G.4
Troussard, A.5
-
11
-
-
10744224916
-
The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange
-
McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, et al. (2004) The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Res 64: 1468-1474.
-
(2004)
Cancer Res
, vol.64
, pp. 1468-1474
-
-
McHardy, L.M.1
Sinotte, R.2
Troussard, A.3
Sheldon, C.4
Church, J.5
-
12
-
-
4344657965
-
Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity
-
Warabi K, McHardy LM, Matainaho L, Van Soest R, Roskelley CD, et al. (2004) Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. J Nat Prod 67: 1387-1389.
-
(2004)
J Nat Prod
, vol.67
, pp. 1387-1389
-
-
Warabi, K.1
McHardy, L.M.2
Matainaho, L.3
van Soest, R.4
Roskelley, C.D.5
-
13
-
-
20044382424
-
Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions
-
McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M (2005) Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Mol Cancer Ther 4: 772-778.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 772-778
-
-
McHardy, L.M.1
Warabi, K.2
Andersen, R.J.3
Roskelley, C.D.4
Roberge, M.5
-
14
-
-
33748607462
-
Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp
-
Diaz-Marrero AR, Austin P, Van Soest R, Matainaho T, Roskelley CD, et al. (2006) Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp. Org Lett 8: 3749-3752.
-
(2006)
Org Lett
, vol.8
, pp. 3749-3752
-
-
Diaz-Marrero, A.R.1
Austin, P.2
van Soest, R.3
Matainaho, T.4
Roskelley, C.D.5
-
15
-
-
25444442624
-
Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells
-
Williams DE, Austin P, Diaz-Marrero AR, Soest RV, Matainaho T, et al. (2005) Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Org Lett 7: 4173-4176.
-
(2005)
Org Lett
, vol.7
, pp. 4173-4176
-
-
Williams, D.E.1
Austin, P.2
Diaz-Marrero, A.R.3
Soest, R.V.4
Matainaho, T.5
-
16
-
-
27644506173
-
Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells
-
Boerner JL, Gibson MA, Fox EM, Posner ED, Parsons SJ, et al. (2005) Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells. Mol Endocrinol 19: 2660-2670.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2660-2670
-
-
Boerner, J.L.1
Gibson, M.A.2
Fox, E.M.3
Posner, E.D.4
Parsons, S.J.5
-
17
-
-
76149117786
-
Chemical synthesis and biological activity of the neopetrosiamides and their analogues: Revision of disulfide bond connectivity
-
Liu H, Boudreau MA, Zheng J, Whittal RM, Austin P, et al. Chemical synthesis and biological activity of the neopetrosiamides and their analogues: revision of disulfide bond connectivity. J Am Chem Soc 132: 1486-1487.
-
J Am Chem Soc
, vol.132
, pp. 1486-1487
-
-
Liu, H.1
Boudreau, M.A.2
Zheng, J.3
Whittal, R.M.4
Austin, P.5
-
18
-
-
0141953996
-
Angiogenesis inhibitors target the endothelial cell cytoskeleton through altered regulation of heat shock protein 27 and cofilin
-
Keezer SM, Ivie SE, Krutzsch HC, Tandle A, Libutti SK, et al. (2003) Angiogenesis inhibitors target the endothelial cell cytoskeleton through altered regulation of heat shock protein 27 and cofilin. Cancer Res 63: 6405-6412.
-
(2003)
Cancer Res
, vol.63
, pp. 6405-6412
-
-
Keezer, S.M.1
Ivie, S.E.2
Krutzsch, H.C.3
Tandle, A.4
Libutti, S.K.5
-
19
-
-
10944235526
-
Proteomic characterization of isolated retinal pigment epithelium microvilli
-
Bonilha VL, Bhattacharya SK, West KA, Sun J, Crabb JW, et al. (2004) Proteomic characterization of isolated retinal pigment epithelium microvilli. Mol Cell Proteomics 3: 1119-1127.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 1119-1127
-
-
Bonilha, V.L.1
Bhattacharya, S.K.2
West, K.A.3
Sun, J.4
Crabb, J.W.5
-
20
-
-
29144530529
-
Proteomic analysis of apical microvillous membranes of syncytiotrophoblast cells reveals a high degree of similarity with lipid rafts
-
Paradela A, Bravo SB, Henriquez M, Riquelme G, Gavilanes F, et al. (2005) Proteomic analysis of apical microvillous membranes of syncytiotrophoblast cells reveals a high degree of similarity with lipid rafts. J Proteome Res 4: 2435-2441.
-
(2005)
J Proteome Res
, vol.4
, pp. 2435-2441
-
-
Paradela, A.1
Bravo, S.B.2
Henriquez, M.3
Riquelme, G.4
Gavilanes, F.5
-
21
-
-
34047155597
-
EHD1 regulates beta1 integrin endosomal transport: Effects on focal adhesions, cell spreading and migration
-
Jovic M, Naslavsky N, Rapaport D, Horowitz M, Caplan S (2007) EHD1 regulates beta1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration. J Cell Sci 120: 802-814.
-
(2007)
J Cell Sci
, vol.120
, pp. 802-814
-
-
Jovic, M.1
Naslavsky, N.2
Rapaport, D.3
Horowitz, M.4
Caplan, S.5
-
22
-
-
0035900711
-
Characterization of EHD4, an EH domain-containing protein expressed in the extracellular matrix
-
Kuo HJ, Tran NT, Clary SA, Morris NP, Glanville RW (2001) Characterization of EHD4, an EH domain-containing protein expressed in the extracellular matrix. J Biol Chem 276: 43103-43110.
-
(2001)
J Biol Chem
, vol.276
, pp. 43103-43110
-
-
Kuo, H.J.1
Tran, N.T.2
Clary, S.A.3
Morris, N.P.4
Glanville, R.W.5
-
23
-
-
43149116767
-
A role for EHD4 in the regulation of early endosomal transport
-
Sharma M, Naslavsky N, Caplan S (2008) A role for EHD4 in the regulation of early endosomal transport. Traffic 9: 995-1018.
-
(2008)
Traffic
, vol.9
, pp. 995-1018
-
-
Sharma, M.1
Naslavsky, N.2
Caplan, S.3
-
24
-
-
24044511771
-
Metabolic activation-related CD147-CD98 complex
-
Xu D, Hemler ME (2005) Metabolic activation-related CD147-CD98 complex. Mol Cell Proteomics 4: 1061-1071.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 1061-1071
-
-
Xu, D.1
Hemler, M.E.2
-
26
-
-
0034681366
-
Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains
-
Zent R, Fenczik CA, Calderwood DA, Liu S, Dellos M, et al. (2000) Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains. J Biol Chem 275: 5059-5064.
-
(2000)
J Biol Chem
, vol.275
, pp. 5059-5064
-
-
Zent, R.1
Fenczik, C.A.2
Calderwood, D.A.3
Liu, S.4
Dellos, M.5
-
27
-
-
38649133357
-
Ecto-59-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells
-
Wang L, Zhou X, Zhou T, Ma D, Chen S, et al. (2008) Ecto-59-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells. J Cancer Res Clin Oncol 134: 365-372.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 365-372
-
-
Wang, L.1
Zhou, X.2
Zhou, T.3
Ma, D.4
Chen, S.5
-
28
-
-
0029030660
-
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand
-
Bowen MA, Patel DD, Li X, Modrell B, Malacko AR, et al. (1995) Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J Exp Med 181: 2213-2220.
-
(1995)
J Exp Med
, vol.181
, pp. 2213-2220
-
-
Bowen, M.A.1
Patel, D.D.2
Li, X.3
Modrell, B.4
Malacko, A.R.5
-
29
-
-
0030049307
-
Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG
-
Park SK, Lee HS, Lee ST (1996) Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG. J Biochem 119: 235-239.
-
(1996)
J Biochem
, vol.119
, pp. 235-239
-
-
Park, S.K.1
Lee, H.S.2
Lee, S.T.3
-
30
-
-
0036264824
-
The ADF/cofilin family: Actin-remodeling proteins
-
reviews3007
-
Maciver SK, Hussey PJ (2002) The ADF/cofilin family: actin-remodeling proteins. Genome Biol 3: reviews3007.
-
(2002)
Genome Biol
, vol.3
-
-
Maciver, S.K.1
Hussey, P.J.2
-
31
-
-
0033521010
-
Cortical actin organization: Lessons from ERM (ezrin/radixin/moesin) proteins
-
Tsukita S, Yonemura S (1999) Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins. J Biol Chem 274: 34507-34510.
-
(1999)
J Biol Chem
, vol.274
, pp. 34507-34510
-
-
Tsukita, S.1
Yonemura, S.2
-
32
-
-
33750487863
-
Myosin-1c couples assembling actin to membranes to drive compensatory endocytosis
-
Sokac AM, Schietroma C, Gundersen CB, Bement WM (2006) Myosin-1c couples assembling actin to membranes to drive compensatory endocytosis. Dev Cell 11: 629-640.
-
(2006)
Dev Cell
, vol.11
, pp. 629-640
-
-
Sokac, A.M.1
Schietroma, C.2
Gundersen, C.B.3
Bement, W.M.4
-
33
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
34
-
-
51049121572
-
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
-
Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, et al. (2008) Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat Cell Biol.
-
(2008)
Nat Cell Biol
-
-
Simpson, K.J.1
Selfors, L.M.2
Bui, J.3
Reynolds, A.4
Leake, D.5
-
36
-
-
70349732865
-
Adhesion-mediated apoptosis resistance in cancer
-
Westhoff MA, Fulda S (2009) Adhesion-mediated apoptosis resistance in cancer. Drug Resist Updat 12: 127-136.
-
(2009)
Drug Resist Updat
, vol.12
, pp. 127-136
-
-
Westhoff, M.A.1
Fulda, S.2
-
37
-
-
42749092828
-
Itinerant exosomes: Emerging roles in cell and tissue polarity
-
Lakkaraju A, Rodriguez-Boulan E (2008) Itinerant exosomes: emerging roles in cell and tissue polarity. Trends Cell Biol 18: 199-209.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 199-209
-
-
Lakkaraju, A.1
Rodriguez-Boulan, E.2
-
38
-
-
0028409113
-
Human breast carcinoma cells cultured in the presence of serum shed membrane vesicles rich in gelatinolytic activities
-
Dolo V, Ginestra A, Ghersi G, Nagase H, Vittorelli ML (1994) Human breast carcinoma cells cultured in the presence of serum shed membrane vesicles rich in gelatinolytic activities. J Submicrosc Cytol Pathol 26: 173-180.
-
(1994)
J Submicrosc Cytol Pathol
, vol.26
, pp. 173-180
-
-
Dolo, V.1
Ginestra, A.2
Ghersi, G.3
Nagase, H.4
Vittorelli, M.L.5
-
39
-
-
55249098470
-
Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles
-
Pluskota E, Woody NM, Szpak D, Ballantyne CM, Soloviev DA, et al. (2008) Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles. Blood 112: 2327-2335.
-
(2008)
Blood
, vol.112
, pp. 2327-2335
-
-
Pluskota, E.1
Woody, N.M.2
Szpak, D.3
Ballantyne, C.M.4
Soloviev, D.A.5
-
40
-
-
33646204913
-
Nodal flow and the generation of left-right asymmetry
-
Hirokawa N, Tanaka Y, Okada Y, Takeda S (2006) Nodal flow and the generation of left-right asymmetry. Cell 125: 33-45.
-
(2006)
Cell
, vol.125
, pp. 33-45
-
-
Hirokawa, N.1
Tanaka, Y.2
Okada, Y.3
Takeda, S.4
-
43
-
-
15244353540
-
Evolution of distinct EGF domains with specific functions
-
Wouters MA, Rigoutsos I, Chu CK, Feng LL, Sparrow DB, et al. (2005) Evolution of distinct EGF domains with specific functions. Protein Sci 14: 1091-1103.
-
(2005)
Protein Sci
, vol.14
, pp. 1091-1103
-
-
Wouters, M.A.1
Rigoutsos, I.2
Chu, C.K.3
Feng, L.L.4
Sparrow, D.B.5
-
44
-
-
0039591721
-
The spasmodic peptide defines a new conotoxin superfamily
-
Lirazan MB, Hooper D, Corpuz GP, Ramilo CA, Bandyopadhyay P, et al. (2000) The spasmodic peptide defines a new conotoxin superfamily. Biochemistry 39: 1583-1588.
-
(2000)
Biochemistry
, vol.39
, pp. 1583-1588
-
-
Lirazan, M.B.1
Hooper, D.2
Corpuz, G.P.3
Ramilo, C.A.4
Bandyopadhyay, P.5
-
45
-
-
29344443859
-
Conotoxins and the posttranslational modification of secreted gene products
-
Buczek O, Bulaj G, Olivera BM (2005) Conotoxins and the posttranslational modification of secreted gene products. Cell Mol Life Sci 62: 3067-3079.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 3067-3079
-
-
Buczek, O.1
Bulaj, G.2
Olivera, B.M.3
-
46
-
-
0031024894
-
NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA
-
Han KH, Hwang KJ, Kim SM, Kim SK, Gray WR, et al. (1997) NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA. Biochemistry 36: 1669-1677.
-
(1997)
Biochemistry
, vol.36
, pp. 1669-1677
-
-
Han, K.H.1
Hwang, K.J.2
Kim, S.M.3
Kim, S.K.4
Gray, W.R.5
-
47
-
-
36749031760
-
The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum
-
Rogers LD, Foster LJ (2007) The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum. Proc Natl Acad Sci U S A 104: 18520-18525.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18520-18525
-
-
Rogers, L.D.1
Foster, L.J.2
-
48
-
-
0037444495
-
Distinct caveolae-mediated endocytic pathways target the Golgi apparatus and the endoplasmic reticulum
-
Le PU, Nabi IR (2003) Distinct caveolae-mediated endocytic pathways target the Golgi apparatus and the endoplasmic reticulum. J Cell Sci 116: 1059-1071.
-
(2003)
J Cell Sci
, vol.116
, pp. 1059-1071
-
-
Le, P.U.1
Nabi, I.R.2
-
49
-
-
0029400480
-
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio F, Grzesiek S, Vuister GW, Zhu G, Pfeifer J, et al. (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6: 277-293.
-
(1995)
J Biomol NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
-
50
-
-
0037316363
-
ARIA: Automated NOE assignment and NMR structure calculation
-
Linge JP, Habeck M, Rieping W, Nilges M (2003) ARIA: automated NOE assignment and NMR structure calculation. Bioinformatics 19: 315-316.
-
(2003)
Bioinformatics
, vol.19
, pp. 315-316
-
-
Linge, J.P.1
Habeck, M.2
Rieping, W.3
Nilges, M.4
-
51
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, et al. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54: 905-921.
-
(1998)
Acta Crystallogr D Biol Crystallogr
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
-
52
-
-
0030039296
-
PROMOTIF-a program to identify and analyze structural motifs in proteins
-
Hutchinson EG, Thornton JM (1996) PROMOTIF-a program to identify and analyze structural motifs in proteins. Protein Sci 5: 212-220.
-
(1996)
Protein Sci
, vol.5
, pp. 212-220
-
-
Hutchinson, E.G.1
Thornton, J.M.2
|