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Volumn 53, Issue 4, 2010, Pages 663-670

Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation

Author keywords

Cholangiocyte; Cholestasis; Hormones; Neuroendocrine; Peptides; Transdifferentiation

Indexed keywords

CYCLOPHILIN B; CYTOKERATIN 19; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; SOMATOMEDIN; TRANSCRIPTION FACTOR PDX 1; VASCULOTROPIN; VASCULOTROPIN A;

EID: 77956267167     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.04.022     Document Type: Article
Times cited : (12)

References (29)
  • 3
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • M.F. Offield, T.L. Jetton, P.A. Labosky, M. Ray, R.W. Stein, and M.A. Magnuson PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum Development 122 1996 983 995
    • (1996) Development , vol.122 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3    Ray, M.4    Stein, R.W.5    Magnuson, M.A.6
  • 4
    • 0032499207 scopus 로고    scopus 로고
    • Regulatory factor linked to late-onset diabetes?
    • S. Dutta, S. Bonner-Weir, M. Montminy, and C. Wright Regulatory factor linked to late-onset diabetes? Nature 392 1998 560
    • (1998) Nature , vol.392 , pp. 560
    • Dutta, S.1    Bonner-Weir, S.2    Montminy, M.3    Wright, C.4
  • 5
    • 19544394114 scopus 로고    scopus 로고
    • The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1)
    • V. Stanojevic, K.M. Yao, and M.K. Thomas The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1) Mol Cell Endocrinol 237 2005 67 74
    • (2005) Mol Cell Endocrinol , vol.237 , pp. 67-74
    • Stanojevic, V.1    Yao, K.M.2    Thomas, M.K.3
  • 6
    • 0036913834 scopus 로고    scopus 로고
    • Pancreatic Duodenal Homeobox (PDX-1) in health and disease
    • D. Melloul, A. Tsur, and D. Zangen Pancreatic Duodenal Homeobox (PDX-1) in health and disease J Pediatr Endocrinol Metab 15 2002 1461 1472
    • (2002) J Pediatr Endocrinol Metab , vol.15 , pp. 1461-1472
    • Melloul, D.1    Tsur, A.2    Zangen, D.3
  • 7
    • 33846031969 scopus 로고    scopus 로고
    • The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter
    • T.B. Deramaudt, M.M. Sachdeva, M.P. Wescott, Y. Chen, D.A. Stoffers, and A.K. Rustgi The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter J Biol Chem 281 2006 38385 38395
    • (2006) J Biol Chem , vol.281 , pp. 38385-38395
    • Deramaudt, T.B.1    Sachdeva, M.M.2    Wescott, M.P.3    Chen, Y.4    Stoffers, D.A.5    Rustgi, A.K.6
  • 8
    • 24344455163 scopus 로고    scopus 로고
    • Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1
    • M. Koizumi, R. Doi, K. Fujimoto, D. Ito, E. Toyoda, and T. Mori Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1 Surgery 138 2005 125 133
    • (2005) Surgery , vol.138 , pp. 125-133
    • Koizumi, M.1    Doi, R.2    Fujimoto, K.3    Ito, D.4    Toyoda, E.5    Mori, T.6
  • 10
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • S. Ferber, A. Halkin, H. Cohen, I. Ber, Y. Einav, and I. Goldberg Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia Nat Med 6 2000 568 572
    • (2000) Nat Med , vol.6 , pp. 568-572
    • Ferber, S.1    Halkin, A.2    Cohen, H.3    Ber, I.4    Einav, Y.5    Goldberg, I.6
  • 11
    • 20344394437 scopus 로고    scopus 로고
    • Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells
    • T. Sapir, K. Shternhall, I. Meivar-Levy, T. Blumenfeld, H. Cohen, and E. Skutelsky Cell-replacement therapy for diabetes: generating functional insulin-producing tissue from adult human liver cells Proc Natl Acad Sci USA 102 2005 7964 7969
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7964-7969
    • Sapir, T.1    Shternhall, K.2    Meivar-Levy, I.3    Blumenfeld, T.4    Cohen, H.5    Skutelsky, E.6
  • 12
    • 0141534119 scopus 로고    scopus 로고
    • Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis
    • T. Miyatsuka, H. Kaneto, Y. Kajimoto, S. Hirota, Y. Arakawa, and Y. Fujitani Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis Biochem Biophys Res Commun 310 2003 1017 1025
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 1017-1025
    • Miyatsuka, T.1    Kaneto, H.2    Kajimoto, Y.3    Hirota, S.4    Arakawa, Y.5    Fujitani, Y.6
  • 13
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • L.L. Baggio, and D.J. Drucker Biology of incretins: GLP-1 and GIP Gastroenterology 132 2007 2131 2157
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 14
    • 67649637819 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis
    • M. Marzioni, G. Alpini, S. Saccomanno, C. Candelaresi, J. Venter, and C. Rychlicki Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis Gut 58 2009 990 997
    • (2009) Gut , vol.58 , pp. 990-997
    • Marzioni, M.1    Alpini, G.2    Saccomanno, S.3    Candelaresi, C.4    Venter, J.5    Rychlicki, C.6
  • 15
    • 34447095397 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis
    • M. Marzioni, G. Alpini, S. Saccomanno, C. Candelaresi, J. Venter, and C. Rychlicki Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis Gastroenterology 133 2007 244 255
    • (2007) Gastroenterology , vol.133 , pp. 244-255
    • Marzioni, M.1    Alpini, G.2    Saccomanno, S.3    Candelaresi, C.4    Venter, J.5    Rychlicki, C.6
  • 16
    • 34247619364 scopus 로고    scopus 로고
    • Gene expression profiles during hepatic stellate cell activation in culture and in vivo
    • S. De Minicis, E. Seki, H. Uchinami, J. Kluwe, Y. Zhang, and D.A. Brenner Gene expression profiles during hepatic stellate cell activation in culture and in vivo Gastroenterology 132 2007 1937 1946
    • (2007) Gastroenterology , vol.132 , pp. 1937-1946
    • De Minicis, S.1    Seki, E.2    Uchinami, H.3    Kluwe, J.4    Zhang, Y.5    Brenner, D.A.6
  • 18
    • 33646472475 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism
    • E. Gaudio, B. Barbaro, D. Alvaro, S. Glaser, H. Francis, and Y. Ueno Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism Gastroenterology 130 2006 1270 1282
    • (2006) Gastroenterology , vol.130 , pp. 1270-1282
    • Gaudio, E.1    Barbaro, B.2    Alvaro, D.3    Glaser, S.4    Francis, H.5    Ueno, Y.6
  • 19
    • 26244464254 scopus 로고    scopus 로고
    • The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis
    • D. Alvaro, V.D. Metalli, G. Alpini, P. Onori, A. Franchitto, and B. Barbaro The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis J Hepatol 43 2005 875 883
    • (2005) J Hepatol , vol.43 , pp. 875-883
    • Alvaro, D.1    Metalli, V.D.2    Alpini, G.3    Onori, P.4    Franchitto, A.5    Barbaro, B.6
  • 20
    • 34848926887 scopus 로고    scopus 로고
    • Serum and biliary insulin-like growth factor i and vascular endothelial growth factor in determining the cause of obstructive cholestasis
    • D. Alvaro, G. Macarri, M.G. Mancino, M. Marzioni, M. Bragazzi, and P. Onori Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis Ann Intern Med 147 2007 451 459
    • (2007) Ann Intern Med , vol.147 , pp. 451-459
    • Alvaro, D.1    MacArri, G.2    Mancino, M.G.3    Marzioni, M.4    Bragazzi, M.5    Onori, P.6
  • 21
    • 67649635785 scopus 로고    scopus 로고
    • GLP-1 analogues: A new therapeutic approach to prevent ductopenia in cholangiopathies?
    • U. Beuers, and B. Goke GLP-1 analogues: a new therapeutic approach to prevent ductopenia in cholangiopathies? Gut 58 2009 902 903
    • (2009) Gut , vol.58 , pp. 902-903
    • Beuers, U.1    Goke, B.2
  • 22
    • 0032533453 scopus 로고    scopus 로고
    • Induction of islet cell neogenesis in the adult pancreas: The partial duct obstruction model
    • L. Rosenberg Induction of islet cell neogenesis in the adult pancreas: the partial duct obstruction model Microsc Res Tech 43 1998 337 346
    • (1998) Microsc Res Tech , vol.43 , pp. 337-346
    • Rosenberg, L.1
  • 23
    • 77955814944 scopus 로고    scopus 로고
    • Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation
    • J.C. Delisle, L. Martignat, J.M. Bach, S. Bosch, and V. Louzier Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation BMC Res Notes 1 2008 136
    • (2008) BMC Res Notes , vol.1 , pp. 136
    • Delisle, J.C.1    Martignat, L.2    Bach, J.M.3    Bosch, S.4    Louzier, V.5
  • 24
    • 33644856603 scopus 로고    scopus 로고
    • Loss of the major duodenal papilla results in brown pigment biliary stone formation in pdx1 null mice
    • A. Fukuda, Y. Kawaguchi, K. Furuyama, S. Kodama, T. Kuhara, and M. Horiguchi Loss of the major duodenal papilla results in brown pigment biliary stone formation in pdx1 null mice Gastroenterology 130 2006 855 867
    • (2006) Gastroenterology , vol.130 , pp. 855-867
    • Fukuda, A.1    Kawaguchi, Y.2    Furuyama, K.3    Kodama, S.4    Kuhara, T.5    Horiguchi, M.6
  • 25
    • 44649117374 scopus 로고    scopus 로고
    • Pancreatic duodenal homeobox factor-1 and diabetes mellitus type 2 (review)
    • F. Al-Quobaili, and M. Montenarh Pancreatic duodenal homeobox factor-1 and diabetes mellitus type 2 (review) Int J Mol Med 21 2008 399 404
    • (2008) Int J Mol Med , vol.21 , pp. 399-404
    • Al-Quobaili, F.1    Montenarh, M.2
  • 26
    • 0035072545 scopus 로고    scopus 로고
    • A bipotential precursor population for pancreas and liver within the embryonic endoderm
    • G. Deutsch, J. Jung, M. Zheng, J. Lora, and K.S. Zaret A bipotential precursor population for pancreas and liver within the embryonic endoderm Development 128 2001 871 881
    • (2001) Development , vol.128 , pp. 871-881
    • Deutsch, G.1    Jung, J.2    Zheng, M.3    Lora, J.4    Zaret, K.S.5
  • 27
    • 22544467743 scopus 로고    scopus 로고
    • Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice
    • K. Shanmukhappa, R. Mourya, G.E. Sabla, J.L. Degen, and J.A. Bezerra Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice Proc Natl Acad Sci USA 102 2005 10182 10187
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10182-10187
    • Shanmukhappa, K.1    Mourya, R.2    Sabla, G.E.3    Degen, J.L.4    Bezerra, J.A.5
  • 28
    • 34548782660 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer-binding protein beta
    • I. Meivar-Levy, T. Sapir, S. Gefen-Halevi, V. Aviv, I. Barshack, and N. Onaca Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer-binding protein beta Hepatology 46 2007 898 905
    • (2007) Hepatology , vol.46 , pp. 898-905
    • Meivar-Levy, I.1    Sapir, T.2    Gefen-Halevi, S.3    Aviv, V.4    Barshack, I.5    Onaca, N.6


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