The Trp64Arg polymorphism of the β3-adrenergic receptor gene is associated with weight changes in obese Japanese men: A 4-year follow-up study

Journal of Physiological Anthropology

Volumn 29, Issue 4, 2010, Pages 133-139

  Yamakita, Mitsuya ^a   Ando, Daisuke ^b   Tang, Sa ^a   Yamagata, Zentaro ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b NATIONAL DEFENSE ACADEMY   (Japan)

Author keywords

3 adrenergic receptor gene; DHPLC; Longitudinal study; Obesity; Polymorphism

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR;

ADULT; ALLELE; ARTICLE; BODY MASS; DNA SEQUENCE; FOLLOW UP; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; HUMAN; JAPAN; MALE; OBESITY; WEIGHT REDUCTION;

ADULT; ALLELES; BODY MASS INDEX; FOLLOW-UP STUDIES; GENE FREQUENCY; HUMANS; JAPAN; MALE; OBESITY; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-3; SEQUENCE ANALYSIS, DNA; WEIGHT LOSS;

EID: 77956259766     PISSN: 18806791     EISSN: 18806805     Source Type: Journal    
DOI: 10.2114/jpa2.29.133     Document Type: Article

References (34)

1. Bessesen DH (2008) Update on obesity. J Clin Endocrinol Metab 93: 2027-2034
2. 3-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos. Int J Obes Relat Metab Disord 21: 1176-1179
3. Blakemore AI, Froguel P (2008) Is obesity our genetic legacy? J Clin Endocrinol Metab 93: S51-56
4. 3-adrenergic receptor: effect modification by age. Ann Nutr Metab 46: 152-158
5. de Luis DA, Aller R, Izaola O, Gonzalez Sagrado M, Conde R (2008) Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients. Ann Nutr Metab 52: 267-271
6. de Luis DA, González Sagrado M, Aller R, Izaola O, Conde R (2009) Influence of Trp64Arg polymorphism of beta 3-adrenoreceptor gene on insulin resistance, adipocytokines and weight loss secondary to two hypocaloric diets. Ann Nutr Metab 54: 104-110
7. Examination Committee of Criteria for "Obesity Disease" in Japan, Japan Society for the Study of Obesity (2002) New criteria for "obesity disease" in Japan. Circ J 66: 987-992
8. 3 adrenoreceptor genes in obese people submitted to a low calorie diet. Int J Obes Relat Metab Disord 20: 1051-1054
9. 3-adrenergic receptor gene is not associated with training-induced changes in body composition: The HERITAGE Family Study. Obes Res 9: 337-341
10. 3-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study. Metabolism 53: 1184-1191
11. Haslam DW, James WP (2005) Obesity. Lancet 366: 1197-1209
12. Kadowaki T, Sekikawa A, Murata K, Maegawa H, Takamiya T, Okamura T, El-Saed A, Miyamatsu N, Edmundowicz D, Kita Y, Sutton-Tyrrell K, Kuller LH, Ueshima H (2006) Japanese men have larger areas of visceral adipose tissue than Caucasian men in the same levels of waist circumference in a population-based study. Int J Obes (Lond) 30: 1163-1165
13. 3-Adrenoceptor polymorphisms relate to subsequent weight gain and blood pressure elevation in obese normotensive individuals. Hypertens Res 29: 951-959
14. 3-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women. Diabetes Res Clin Pract 54: 49-55
15. Kurokawa N, Young EH, Oka Y, Satoh H, Wareham NJ, Sandhu MS, Loos RJ (2008) The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44,833 individuals. Int J Obes (Lond) 32: 1240-1249
16. Masuo K, Katsuya T, Fu Y, Rakugi H, Ogihara T, Tuck ML (2005) Beta2-and beta3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 years. Circulation 111: 3429-3434
17. 3-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis. J Clin Endocrinol Metab 88: 5914-5920
18. Murakami Y, Miura K, Ueshima H (2009) Comparison of the trends and current status of obesity between Japan and other developed countries. Nippon Rinsho 67: 245-252 [In Japanese with English Abstract]
19. 3-adrenergic receptor gene and obesity in Japanese men: a longitudinal analysis. J Clin Endocrinol Metab 82: 1284-1287
20. Phares DA, Halverstadt AA, Shuldiner AR, Ferrell RE, Douglass LW, Ryan AS, Goldberg AP, Hagberg JM (2004) Association between body fat response to exercise training and multilocus ADR genotypes. Obes Res 12: 807-815
21. Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Pérusse L, Bouchard C (2006) The human obesity gene map: the 2005 update. Obesity (Silver Spring) 14: 529-644
22. 3-adrenoceptor gene variant on weight loss, body composition, or energy expenditure in obese, Caucasian postmenopausal women. Metabolism 51: 801-805
23. 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients. Diabetes Care 20: 1887-1890
24. Sato S, Demura S (2009) Regional subcutaneous fat characteristics stratified by sex, age, and obesity, and their relationships with total and visceral fat in a Japanese population. J Physiol Anthropol 28: 231-238
25. Shiwaku K, Gao TQ, Isobe A, Fukushima T, Yamane Y (1998) A Trp 64 Arg mutation in the beta3-adrenergic receptor gene is not associated with moderate overweight in Japanese workers. Metabolism 47: 1528-1530
26. 3-adrenergic receptor gene. Int J Obes Relat Metab Disord 27: 1028-1036
27. Tamaki S, Nakamura Y, Tabara Y, Okamura T, Kita Y, Kadowaki T, Tsujita Y, Horie M, Miki T, Ueshima H (2006) Relationship between metabolic syndrome and Trp64arg polymorphism of the beta-adrenergic receptor gene in a general sample: the Shigaraki study. Hypertens Res 29: 891-896
28. Tchernof A, Starling RD, Turner A, Shuldiner AR, Walston JD, Silver K, Poehlman ET (2000) Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg β3-adrenoceptor gene variant. Diabetes 49: 1709-1713
29. 3-adrenoceptor as a therapeutic target: current perspectives. Pharmacol Res 59: 221-234
30. 3-adrenergic-receptor gene and response to treatment of obesity. Lancet 346: 1433-1434
31. 3-adrenergic-receptor gene. N Engl J Med 333: 343-347
32. Weiss EC, Galuska DA, Kettel Khan L, Gillespie C, Serdula MK (2007) Weight regain in U.S. adults who experienced substantial weight loss, 1999-2002. Am J Prev Med 33: 34-40
33. Widén E, Lehto M, Kanninen T, Walston J, Shuldiner AR, Groop LC (1995) Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med 333: 348-351
34. Wu T, Gao X, Chen M, van Dam RM (2009) Long-term effectiveness of diet-plus-exercise interventions vs. diet-only interventions for weight loss: a meta-analysis. Obes Rev 10: 313-323