Human equilibrative nucleoside transporter-3 (hENT3) spectrum disorder mutations impair nucleoside transport, protein localization, and stability

Journal of Biological Chemistry

Volumn 285, Issue 36, 2010, Pages 28343-28352

  Kang, Nayoung ^a   Jun, Ah Hyun ^a   Bhutia, Yangzom Doma ^a   Kannan, Natarajan ^b   Unadkat, Jashvant D ^c   Govindarajan, Rajgopal ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b Department of Biochemistry and Molecular Biology University of Georgia ^*  (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BIOMOLECULES; ENZYME INHIBITION; INSULIN; MITOCHONDRIA; PROTEINS;

BIOCHEMICAL CHARACTERIZATION; CLINICAL MANIFESTATION; DIABETES MELLITUS; HUMAN GENETIC DISORDERS; HYPERPIGMENTATION; IMMUNE CELLS; INSULIN-DEPENDENT DIABETES; LYMPH NODE; LYMPHADENOPATHY; NUCLEOSIDE TRANSPORT; NUCLEOSIDE TRANSPORTERS; PATHOPHYSIOLOGY; PROTEIN LOCALIZATION;

DISEASES;

ADENOSINE; ARGININE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3; GLYCINE; UNCLASSIFIED DRUG; NUCLEOSIDE; NUCLEOSIDE TRANSPORTER; SLC29A3 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENETIC DISORDER; GOLGI COMPLEX; H SYNDROME AND PIGMENTED HYPERTRICHOTIC DERMATOSIS WITH INSULIN DEPENDENT DIABETES; MISSENSE MUTATION; NONHUMAN; NONSENSE MUTATION; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; XENOPUS; 3T3 CELL LINE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DISEASES; GENETICS; HUMAN; KINETICS; LYSOSOME; METABOLISM; MOUSE; MUTATION; PROTEIN CONFORMATION; PROTEIN TRANSPORT;

ADENOSINE; ANIMALS; DISEASE; ENDOPLASMIC RETICULUM; GLYCINE; GOLGI APPARATUS; HUMANS; KINETICS; LYSOSOMES; MICE; MODELS, MOLECULAR; MUTATION; NIH 3T3 CELLS; NUCLEOSIDE TRANSPORT PROTEINS; NUCLEOSIDES; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN TRANSPORT;

EID: 77956255671     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.109199     Document Type: Article

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