메뉴 건너뛰기




Volumn 19, Issue 10, 2010, Pages 1219-1228

Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients

Author keywords

cytokine; gene polymorphism; IL18; IL4; STAT6; systemic lupus erythematosus

Indexed keywords

CYTOKINE; INTERLEUKIN 4; STAT6 PROTEIN;

EID: 77956239438     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203310371152     Document Type: Article
Times cited : (45)

References (48)
  • 1
    • 40049093765 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Rahman A., Isenberg DA Systemic lupus erythematosus. N Engl J Med 2008 ; 358: 929-939.
    • (2008) N Engl J Med , vol.358 , pp. 929-939
    • Rahman, A.1    Isenberg, D.A.2
  • 2
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996 ; 17: 138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 3
    • 0032518439 scopus 로고    scopus 로고
    • Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRLlpr mice
    • Balomenos D., Rumold R., Theofilopoulos AN Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRLlpr mice. J Clin Invest 1998 ; 101: 364-371.
    • (1998) J Clin Invest , vol.101 , pp. 364-371
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 4
    • 0030953632 scopus 로고    scopus 로고
    • Roles of interferon-gamma and interleukin-4 in murine lupus
    • Peng SL, Moslehi J., Craft J. Roles of interferon-gamma and interleukin-4 in murine lupus. J Clin Invest 1997 ; 99: 1936-1946.
    • (1997) J Clin Invest , vol.99 , pp. 1936-1946
    • Peng, S.L.1    Moslehi, J.2    Craft, J.3
  • 5
    • 0031036084 scopus 로고    scopus 로고
    • Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome
    • Santiago ML, Fossati L., Jacquet C., Muller W., Izui S., Reininger L. Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome. J Exp Med 1997 ; 185: 65-70.
    • (1997) J Exp Med , vol.185 , pp. 65-70
    • Santiago, M.L.1    Fossati, L.2    Jacquet, C.3    Muller, W.4    Izui, S.5    Reininger, L.6
  • 6
    • 0029129961 scopus 로고
    • Enssle KH. Modulation of the immunoglobulin dysregulation in GvH- and SLE-like diseases by the murine IL-4 receptor (IL-4-R)
    • Schorlemmer HU, Dickneite G., Kanzy EJ, Enssle KH. Modulation of the immunoglobulin dysregulation in GvH- and SLE-like diseases by the murine IL-4 receptor (IL-4-R). Inflamm Res 1995 ; 44 (Suppl 2). S194 - S196.
    • (1995) Inflamm Res , vol.44 , Issue.2
    • Schorlemmer, H.U.1    Dickneite, G.2    Kanzy, E.J.3
  • 7
    • 0028081880 scopus 로고
    • Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice
    • Ishida H., Muchamuel T., Sakaguchi S., Andrade S., Menon S., Howard M. Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J Exp Med 1994 ; 179: 305-310.
    • (1994) J Exp Med , vol.179 , pp. 305-310
    • Ishida, H.1    Muchamuel, T.2    Sakaguchi, S.3    Andrade, S.4    Menon, S.5    Howard, M.6
  • 8
    • 33846235990 scopus 로고    scopus 로고
    • Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus
    • Lit LC, Wong CK, Li EK, Tam LS, Lam CW, Lo YM Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus. J Rheumatol 2007 ; 34: 89-96.
    • (2007) J Rheumatol , vol.34 , pp. 89-96
    • Lit, L.C.1    Wong, C.K.2    Li, E.K.3    Tam, L.S.4    Lam, C.W.5    Lo, Y.M.6
  • 9
    • 0036711223 scopus 로고    scopus 로고
    • Decreased IL-4 producing CD4+ T cells in patients with active systemic lupus erythematosus-relation to IL-12R expression
    • Sugimoto K., Morimoto S., Kaneko H., et al. Decreased IL-4 producing CD4+ T cells in patients with active systemic lupus erythematosus-relation to IL-12R expression. Autoimmunity 2002 ; 35: 381-387.
    • (2002) Autoimmunity , vol.35 , pp. 381-387
    • Sugimoto, K.1    Morimoto, S.2    Kaneko, H.3
  • 10
    • 0032927145 scopus 로고    scopus 로고
    • Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)-relation to Th1- and Th2-derived cytokines
    • Tokano Y., Morimoto S., Kaneko H., et al. Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)-relation to Th1- and Th2-derived cytokines. Clin Exp Immunol 1999 ; 116: 169-173.
    • (1999) Clin Exp Immunol , vol.116 , pp. 169-173
    • Tokano, Y.1    Morimoto, S.2    Kaneko, H.3
  • 11
    • 0025921924 scopus 로고
    • TH2 cells in systemic autoimmunity: Insights from allogeneic diseases and chemically-induced autoimmunity
    • Goldman M., Druet P., Gleichmann E. TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity. Immunol Today 1991 ; 12: 223-227.
    • (1991) Immunol Today , vol.12 , pp. 223-227
    • Goldman, M.1    Druet, P.2    Gleichmann, E.3
  • 12
    • 0031804643 scopus 로고    scopus 로고
    • Decreased Th1-like and increased Th2-like cells in systemic lupus erythematosus
    • Funauchi M., Ikoma S., Enomoto H., Horiuchi A. Decreased Th1-like and increased Th2-like cells in systemic lupus erythematosus. Scand J Rheumatol 1998 ; 27: 219-224.
    • (1998) Scand J Rheumatol , vol.27 , pp. 219-224
    • Funauchi, M.1    Ikoma, S.2    Enomoto, H.3    Horiuchi, A.4
  • 13
    • 0034532208 scopus 로고    scopus 로고
    • Increased interferon-gamma (IFN-gamma), IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)
    • Csiszar A., Nagy G., Gergely P., Pozsonyi T., Pocsik E. Increased interferon-gamma (IFN-gamma), IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 2000 ; 122: 464-470.
    • (2000) Clin Exp Immunol , vol.122 , pp. 464-470
    • Csiszar, A.1    Nagy, G.2    Gergely, P.3    Pozsonyi, T.4    Pocsik, E.5
  • 14
    • 17044461280 scopus 로고    scopus 로고
    • Th1/Th2 cytokines in patients with systemic lupus erythematosus: Is tumor necrosis factor alpha protective?
    • Gomez D., Correa PA, Gomez LM, Cadena J., Molina JF, Anaya JM Th1/Th2 cytokines in patients with systemic lupus erythematosus: is tumor necrosis factor alpha protective? Semin Arthritis Rheum 2004 ; 33: 404-413.
    • (2004) Semin Arthritis Rheum , vol.33 , pp. 404-413
    • Gomez, D.1    Correa, P.A.2    Gomez, L.M.3    Cadena, J.4    Molina, J.F.5    Anaya, J.M.6
  • 15
    • 0032939098 scopus 로고    scopus 로고
    • Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)
    • Viallard JF, Pellegrin JL, Ranchin V., et al. Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 1999 ; 115: 189-195.
    • (1999) Clin Exp Immunol , vol.115 , pp. 189-195
    • Viallard, J.F.1    Pellegrin, J.L.2    Ranchin, V.3
  • 16
    • 0033772374 scopus 로고    scopus 로고
    • Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus
    • Wong CK, Ho CY, Li EK, Lam CW Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 2000 ; 9: 589-593.
    • (2000) Lupus , vol.9 , pp. 589-593
    • Wong, C.K.1    Ho, C.Y.2    Li, E.K.3    Lam, C.W.4
  • 18
    • 0347928790 scopus 로고    scopus 로고
    • Polymorphisms of the interleukin-4 gene in Chinese patients with systemic lupus erythematosus in Taiwan
    • Wu MC, Huang CM, Tsai JJ, Chen HY, Tsai FJ Polymorphisms of the interleukin-4 gene in Chinese patients with systemic lupus erythematosus in Taiwan. Lupus 2003 ; 12: 21-25.
    • (2003) Lupus , vol.12 , pp. 21-25
    • Wu, M.C.1    Huang, C.M.2    Tsai, J.J.3    Chen, H.Y.4    Tsai, F.J.5
  • 19
    • 0033031986 scopus 로고    scopus 로고
    • Association of interleukin-4 receptor and interleukin-4 promoter gene polymorphisms with systemic lupus erythematosus
    • Kanemitsu S., Takabayashi A., Sasaki Y., et al. Association of interleukin-4 receptor and interleukin-4 promoter gene polymorphisms with systemic lupus erythematosus. Arthritis Rheum 1999 ; 42: 1298-1300.
    • (1999) Arthritis Rheum , vol.42 , pp. 1298-1300
    • Kanemitsu, S.1    Takabayashi, A.2    Sasaki, Y.3
  • 20
    • 0035041157 scopus 로고    scopus 로고
    • Interleukin-6 promoter polymorphism (-174 G/C) in Caucasian German patients with systemic lupus erythematosus
    • Oxford)
    • Schotte H., Schluter B., Rust S., Assmann G., Domschke W., Gaubitz M. Interleukin-6 promoter polymorphism (-174 G/C) in Caucasian German patients with systemic lupus erythematosus. Rheumatology (Oxford) 2001 ; 40: 393-400.
    • (2001) Rheumatology , vol.40 , pp. 393-400
    • Schotte, H.1    Schluter, B.2    Rust, S.3    Assmann, G.4    Domschke, W.5    Gaubitz, M.6
  • 21
    • 33645159126 scopus 로고    scopus 로고
    • Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility
    • Lee YH, Harley JB, Nath SK Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. Eur J Hum Genet 2006 ; 14: 364-371.
    • (2006) Eur J Hum Genet , vol.14 , pp. 364-371
    • Lee, Y.H.1    Harley, J.B.2    Nath, S.K.3
  • 22
    • 0347320524 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: A population based study in the southeastern United States
    • Parks CG, Cooper GS, Dooley MA, et al. Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. Ann Rheum Dis 2004 ; 63: 91-94.
    • (2004) Ann Rheum Dis , vol.63 , pp. 91-94
    • Parks, C.G.1    Cooper, G.S.2    Dooley, M.A.3
  • 23
    • 4644299001 scopus 로고    scopus 로고
    • Association of interleukin-10 promoter polymorphisms with systemic lupus erythematosus
    • Chong WP, Ip WK, Wong WH, Lau CS, Chan TM, Lau YL Association of interleukin-10 promoter polymorphisms with systemic lupus erythematosus. Genes Immun 2004 ; 5: 484-492.
    • (2004) Genes Immun , vol.5 , pp. 484-492
    • Chong, W.P.1    Ip, W.K.2    Wong, W.H.3    Lau, C.S.4    Chan, T.M.5    Lau, Y.L.6
  • 24
    • 70350755715 scopus 로고    scopus 로고
    • Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus
    • Sanchez E., Palomino-Morales RJ, Ortego-Centeno N., et al. Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus. Hum Mol Genet 2009 ; 18: 3739-3748.
    • (2009) Hum Mol Genet , vol.18 , pp. 3739-3748
    • Sanchez, E.1    Palomino-Morales, R.J.2    Ortego-Centeno, N.3
  • 25
    • 34250191054 scopus 로고    scopus 로고
    • Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients
    • Lin YJ, Wan L., Lee CC, et al. Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients. Genes Immun 2007 ; 8: 302-307.
    • (2007) Genes Immun , vol.8 , pp. 302-307
    • Lin, Y.J.1    Wan, L.2    Lee, C.C.3
  • 26
    • 40449139904 scopus 로고    scopus 로고
    • A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients
    • Lin YJ, Wan L., Sheu JJ, et al. A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients. Lupus 2008 ; 17: 124-127.
    • (2008) Lupus , vol.17 , pp. 124-127
    • Lin, Y.J.1    Wan, L.2    Sheu, J.J.3
  • 27
    • 0345411335 scopus 로고    scopus 로고
    • The ubiquitous nature of epistasis in determining susceptibility to common human diseases
    • Moore JH The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 2003 ; 56: 73-82.
    • (2003) Hum Hered , vol.56 , pp. 73-82
    • Moore, J.H.1
  • 28
    • 0035147109 scopus 로고    scopus 로고
    • Genetic association between interleukin-10 promoter region polymorphisms and primary Sjogren's syndrome
    • Hulkkonen J., Pertovaara M., Antonen J., Lahdenpohja N., Pasternack A., Hurme M. Genetic association between interleukin-10 promoter region polymorphisms and primary Sjogren's syndrome. Arthritis Rheum 2001 ; 44: 176-179.
    • (2001) Arthritis Rheum , vol.44 , pp. 176-179
    • Hulkkonen, J.1    Pertovaara, M.2    Antonen, J.3    Lahdenpohja, N.4    Pasternack, A.5    Hurme, M.6
  • 29
    • 0346877501 scopus 로고    scopus 로고
    • A TaqI polymorphism in the 3'UTR of the IL-12 p40 gene correlates with increased IL-12 secretion
    • Seegers D., Zwiers A., Strober W., Pena AS, Bouma G. A TaqI polymorphism in the 3'UTR of the IL-12 p40 gene correlates with increased IL-12 secretion. Genes Immun 2002 ; 3: 419-423.
    • (2002) Genes Immun , vol.3 , pp. 419-423
    • Seegers, D.1    Zwiers, A.2    Strober, W.3    Pena, A.S.4    Bouma, G.5
  • 30
    • 0035205687 scopus 로고    scopus 로고
    • Cloning and mutation analysis of the human IL-18 promoter: A possible role of polymorphisms in expression regulation
    • Giedraitis V., He B., Huang WX, Hillert J. Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol 2001 ; 112: 146-152.
    • (2001) J Neuroimmunol , vol.112 , pp. 146-152
    • Giedraitis, V.1    He, B.2    Huang, W.X.3    Hillert, J.4
  • 31
    • 0036772222 scopus 로고    scopus 로고
    • Genetics of IL-13 and functional relevance of IL-13 variants
    • Vercelli D. Genetics of IL-13 and functional relevance of IL-13 variants. Curr Opin Allergy Clin Immunol 2002 ; 2: 389-393.
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , pp. 389-393
    • Vercelli, D.1
  • 32
    • 0028789831 scopus 로고
    • Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
    • discussion 95-76
    • Rosenwasser LJ, Klemm DJ, Dresback JK, et al. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995 ; 25 (Suppl 2). 74-78 ; discussion 95-76.
    • (1995) Clin Exp Allergy , vol.25 , Issue.2 , pp. 74-78
    • Rosenwasser, L.J.1    Klemm, D.J.2    Dresback, J.K.3
  • 33
    • 7944228165 scopus 로고    scopus 로고
    • A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels
    • Schedel M., Carr D., Klopp N., et al. A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels. J Allergy Clin Immunol 2004 ; 114: 1100-1105.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1100-1105
    • Schedel, M.1    Carr, D.2    Klopp, N.3
  • 34
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
    • Hochberg MC Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997 ; 40: 1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 35
    • 33646749338 scopus 로고    scopus 로고
    • A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians
    • Yang HC, Lin CH, Hsu CL, et al. A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. J Biomed Sci 2006 ; 13: 489-498.
    • (2006) J Biomed Sci , vol.13 , pp. 489-498
    • Yang, H.C.1    Lin, C.H.2    Hsu, C.L.3
  • 36
    • 33750386307 scopus 로고    scopus 로고
    • The association of single nucleotide polymorphisms in the MMP-9 genes with susceptibility to acute primary angle closure glaucoma in Taiwanese patients
    • Wang IJ, Chiang TH, Shih YF, et al. The association of single nucleotide polymorphisms in the MMP-9 genes with susceptibility to acute primary angle closure glaucoma in Taiwanese patients. Mol Vis 2006 ; 12: 1223-1232.
    • (2006) Mol Vis , vol.12 , pp. 1223-1232
    • Wang, I.J.1    Chiang, T.H.2    Shih, Y.F.3
  • 37
    • 0028857136 scopus 로고
    • Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus
    • Klipper-Aurbach Y., Wasserman M., Braunspiegel-Weintrob N., et al. Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus. Med Hypotheses 1995 ; 45: 486-490.
    • (1995) Med Hypotheses , vol.45 , pp. 486-490
    • Klipper-Aurbach, Y.1    Wasserman, M.2    Braunspiegel-Weintrob, N.3
  • 38
    • 34249662218 scopus 로고    scopus 로고
    • A new JAVA interface implementation of THESIAS: Testing haplotype effects in association studies
    • Tregouet DA, Garelle V. A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies. Bioinformatics 2007 ; 23: 1038-1039.
    • (2007) Bioinformatics , vol.23 , pp. 1038-1039
    • Tregouet, D.A.1    Garelle, V.2
  • 39
    • 0037433052 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    • Hahn LW, Ritchie MD, Moore JH Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics 2003 ; 19: 376-382.
    • (2003) Bioinformatics , vol.19 , pp. 376-382
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 40
    • 33845669548 scopus 로고    scopus 로고
    • Complex gene-gene interactions in multiple sclerosis: A multifactorial approach reveals associations with inflammatory genes
    • Motsinger AA, Brassat D., Caillier SJ, et al. Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes. Neurogenetics 2007 ; 8: 11-20.
    • (2007) Neurogenetics , vol.8 , pp. 11-20
    • Motsinger, A.A.1    Brassat, D.2    Caillier, S.J.3
  • 41
    • 69349098495 scopus 로고    scopus 로고
    • An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression
    • Schedel M., Frei R., Bieli C., et al. An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression. J Allergy Clin Immunol 2009 ; 124: 583-589.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 583-589
    • Schedel, M.1    Frei, R.2    Bieli, C.3
  • 42
    • 31944434114 scopus 로고    scopus 로고
    • IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma
    • Kabesch M., Schedel M., Carr D., et al. IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma. J Allergy Clin Immunol 2006 ; 117: 269-274.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 269-274
    • Kabesch, M.1    Schedel, M.2    Carr, D.3
  • 44
    • 1842417145 scopus 로고    scopus 로고
    • Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice
    • Erb KJ, Ruger B., von Brevern M., Ryffel B., Schimpl A., Rivett K. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. J Exp Med 1997 ; 185: 329-339.
    • (1997) J Exp Med , vol.185 , pp. 329-339
    • Erb, K.J.1    Ruger, B.2    Von Brevern, M.3    Ryffel, B.4    Schimpl, A.5    Rivett, K.6
  • 45
    • 0037406914 scopus 로고    scopus 로고
    • Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis
    • Singh RR, Saxena V., Zang S., et al. Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis. J Immunol 2003 ; 170: 4818-4825.
    • (2003) J Immunol , vol.170 , pp. 4818-4825
    • Singh, R.R.1    Saxena, V.2    Zang, S.3
  • 46
    • 0034331476 scopus 로고    scopus 로고
    • Measurement of intracellular interferon-gamma and interleukin-4 in whole blood T lymphocytes from patients with systemic lupus erythematosus
    • Nagy G., Pallinger E., Antal-Szalmas P., et al. Measurement of intracellular interferon-gamma and interleukin-4 in whole blood T lymphocytes from patients with systemic lupus erythematosus. Immunol Lett 2000 ; 74: 207-210.
    • (2000) Immunol Lett , vol.74 , pp. 207-210
    • Nagy, G.1    Pallinger, E.2    Antal-Szalmas, P.3
  • 47
    • 34247402021 scopus 로고    scopus 로고
    • Interleukin-18 promoter gene polymorphisms in Chinese patients with systemic lupus erythematosus: Association with CC genotype at position -607
    • Xu Q., Tin SK, Sivalingam SP, Thumboo J., Koh DR, Fong KY Interleukin-18 promoter gene polymorphisms in Chinese patients with systemic lupus erythematosus: association with CC genotype at position -607. Ann Acad Med Singapore 2007 ; 36: 91-95.
    • (2007) Ann Acad Med Singapore , vol.36 , pp. 91-95
    • Xu, Q.1    Tin, S.K.2    Sivalingam, S.P.3    Thumboo, J.4    Koh, D.R.5    Fong, K.Y.6
  • 48
    • 62749137483 scopus 로고    scopus 로고
    • Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis
    • Chen DY, Hsieh CW, Chen KS, Chen YM, Lin FJ, Lan JL Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis. Lupus 2009 ; 18: 29-37.
    • (2009) Lupus , vol.18 , pp. 29-37
    • Chen, D.Y.1    Hsieh, C.W.2    Chen, K.S.3    Chen, Y.M.4    Lin, F.J.5    Lan, J.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.