The effect of nicotine on visuospatial attention in chronic spatial neglect depends upon lesion location

Journal of Psychopharmacology

Volumn 24, Issue 9, 2010, Pages 1357-1365

  Vossel, S ^a   Kukolja, J ^a,b   Thimm, M ^a,c   Thiel, C M ^a,d   Fink, G R ^a,b  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d UNIVERSITY OF OLDENBURG   (Germany)

Author keywords

acetylcholine; attention; spatial neglect

Indexed keywords

NICOTINE GUM; PLACEBO;

ACCURACY; ADULT; AGED; ARTICLE; ASSOCIATION; ATTENTION; BRAIN DAMAGE; BRAIN MAPPING; BRAIN REGION; CHOLINERGIC STIMULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEPTH PERCEPTION; DIZZINESS; DOUBLE BLIND PROCEDURE; FEMALE; HEADACHE; HUMAN; MALE; NAUSEA; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; PRIORITY JOURNAL; REACTION TIME; SPATIAL NEGLECT SYNDROME; TEMPORAL LOBE; VALIDITY;

ADULT; AGED; AGNOSIA; ATTENTION; BRAIN MAPPING; CROSS-OVER STUDIES; CUES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NICOTINE; NICOTINIC AGONISTS; ORGAN SPECIFICITY; PARIETAL LOBE; POLYMETHACRYLIC ACIDS; POLYVINYLS; REACTION TIME; TEMPORAL LOBE;

EID: 77956224812     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881109105397     Document Type: Article

References (47)

1. Barrett, AM, Crucian, GP, Schwartz, RL, Heilman, KM (1999) Adverse effect of dopamine agonist therapy in a patient with motor-intentional neglect. Arch Phys Med Rehabil 80: 600-603.
2. Bates, E., Wilson, SM, Saygin, AP, Dick, F., Sereno, MI, Knight, RT, et al. (2003) Voxel-based lesion-symptom mapping. Nat Neurosci 6: 448-450.
3. Beane, M., Drew, A., Massey, K., Marrocco, R. (2002) Infusion of Cholinergic and Noradrenergic Agents into Rat Posterior Parietal Cortex Modifies Orienting and Alerting Components of Covert Visual Attention. Program No 674 13 Abstract Viewer/Iternary Planner. Washington, DC: Society for Neuroscience (Online).
4. Bell, EC, Willson, MC, Wilman, AH, Dave, S., Silverstone, PH (2006) Males and females differ in brain activation during cognitive tasks. Neuroimage 30: 529-538.
5. Benowitz, NL, Porchet, H., Sheiner, L., Jacob, P. (1988) Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clin Pharmacol Ther 44: 23-28.
6. Cherney, LR, Halper, AS, Kwasnica, CM, Harvey, RL, Zhang, M. (2001) Recovery of functional status after right hemisphere stroke: relationship with unilateral neglect. Arch Phys Med Rehabil 82: 322-328.
7. Crinion, J., Ashburner, J., Leff, A., Brett, M., Price, C., Friston, K. (2007) Spatial normalization of lesioned brains: performance evaluation and impact on fMRI analyses. Neuroimage 37: 866-875.
8. Fels, M., Geissner, E. (1997) Neglect-Test (NET). Göttingen: Hogrefe.
9. File, SE, Fluke, F., Leahy, A. (2001) Nicotine has calming effects on stress-induced mood changes in females, but enhances aggressive mood in males. Int J Neuropsychopharmacol 4: 371-376.
10. Geminiani, G., Bottini, G., Sterzi, R. (1998) Dopaminergic stimulation in unilateral neglect. J Neurol Neurosurg Psychiatry 65: 344-347.
11. Giessing, C., Fink, GR, Rösler, F., Thiel, CM (2007) fMRI data predict individual differences of behavioural effects of nicotine: a partial least square analysis. J Cogn Neurosci 19: 658-670.
12. Giessing, C., Thiel, CM, Rösler, F., Fink, GR (2006) The modulatory effects of nicotine on parietal cortex depend on cue reliability. Neuroscience 137: 853-864.
13. Glover, S., Castiello, U. (2006) Recovering space in unilateral neglect: a neurological dissociation revealed by virtual reality. J Cogn Neurosci 18: 833-843.
14. Gotti, C., Clementi, F. (2004) Neuronal nicotinic receptors: from structure to pathology. Prog Neurobiol 74: 363-396.
15. Grujic, Z., Mapstone, M., Gitelman, D., Weintraub, S., Johnson, N., Hays, A., et al. (1998) Dopamine agonists reorient visual exploration away from the neglected hemispace. Neurology 5: 1395-1398.
16. Halligan, PW, Cockburn, JM (1993) Cognitive sequelae of stroke: visuospatial and memory disorders. Crit Rev Phys Rehabil Med 5: 57-81.
17. Halligan, PW, Fink, GR, Marshall, JC, Vallar, G. (2003) Spatial cognition: evidence from visual neglect. Trends Cogn Sci 7: 125-133.
18. Heilman, KM, Valenstein, E., Watson, RT (2000) Neglect and related disorders. Sem Neurol 20: 463-470.
19. Kleinman, JT, Gottesman, RF, Davis, C., Newhart, M., Heidler-Gary, J., Hillis, AE (2008) Gender differences in unilateral spatial neglect within 24 hours of ischemic stroke. Brain Cogn 68: 49-52.
20. Lawrence, NS, Ross, TJ, Stein, EA (2002) Cognitive mechanisms of nicotine on visual attention. Neuron 36: 539-548.
21. Malhotra, PA, Parton, AD, Greenwood, R., Husain, M. (2006) Noradrenergic modulation of space exploration in visual neglect. Ann Neurol 59: 186-190.
22. Mesulam, MM (1999) Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events. Philos Trans R Soc Lond B Biol Sci 354: 1325-1346.
23. Mukand, JA, Guilmette, TJ, Allen, DG, Brown, LK, Brown, SL, Tober, KL, et al. (2001) Dopaminergic therapy with carbidopa L-Dopa for left neglect after stroke: a case series. Arch Phys Med Rehabil 82: 1279-1282.
24. Murphy, FC, Klein, RM (1998) The effects of nicotine on spatial and non-spatial expectancies in a covert orienting task. Neuropsychologia 36: 1103-1114.
25. Newhouse, PA, Potter, A., Singh, A. (2004) Effects of nicotinic stimulation on cognitive performance. Curr Opin Pharmacol 4: 36-46.
26. Nyberg, G., Panfilov, V., Sivertsson, R., Wilhelmsen, L. (1982) Cardiovascular effects of nicotine chewing gum in healthy non-smokers. Eur J Clin Pharmacol 23: 303-307.
27. Oldfield, RC (1971) The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 9: 97-113.
28. Phillips, JM, McAlonan, K., Robb, WGK, Brown, VJ (2000) Cholinergic neurotransmission influences covert orientation of visuospatial attention in the rat. Psychopharmacology 150: 112-116.
29. Posner, MI (1980) Orienting of attention. Q J Exp Psychol 32: 3-25.
30. Posner, MI, Fan, J. (2004) Attention as an Organ System (Neurobiology of Perception and Communication: From Synapse to Society. The IVth De Lange Conference). Cambridge: Cambridge University Press.
31. Posner, MI, Walker, JA, Friedrich, FJ, Rafal, RD (1984) Effects of parietal injury on covert orienting of attention. J Neurosci 4: 1863-1874.
32. Robertson, IH, Halligan, PW (1999) Spatial neglect: a clinical handbook for diagnosis and treatment. Hove: Psychology Press.
33. Robertson, IH, Mattingley, JB, Rorden, C., Driver, J. (1998) Phasic alerting of neglect patients overcomes their spatial deficit in visual awareness. Nature 395: 169-172.
34. Robertson, IH, Tegner, R., Tham, K., Lo, A., Nimmo-Smith, I. (1995) Sustained attention training for unilateral neglect: theoretical and rehabilitation implications. J Clin Exp Neuropsychol 17: 416-430.
35. Rorden, C., Karnath, HO (2004) Using human brain lesions to infer function: a relic from a past era in the fMRI age ? Nat Rev Neurosci 5: 813-819.
36. Rorden, C., Karnath, HO, Bonilha, L. (2007) Improving lesion-symptom mapping. J Cogn Neurosci 19: 1081-1088.
37. Singer, S., Rossi, S., Verzosa, S., Hashim, A., Lonow, R., Cooper, T. (2004) Nicotine-induced changes in neurotransmitter levels in brain areas associated with cognitive function. Neurochem Res 29: 1779-1792.
38. Steward, C., Burke, S., Marrocco, R. (2001) Cholinergic modulation of covert attention in the rat. Psychopharmacology 155: 210-218.
39. Thiel, CM, Fink, GR (2008) Effects of the cholinergic agonist nicotine on reorienting of visual spatial attention and top-down attentional control. Neuroscience 152: 381-390.
40. Thiel, CM, Zilles, K., Fink, GR (2005) Nicotine modulates reorienting of visuospatial attention and neural activity in human parietal cortex. Neuropsychopharmacology 30: 810-820.
41. Thimm, M., Fink, GR, Küst, J., Karbe, H., Sturm, W. (2006) Impact of alertness-training on spatial neglect: a behavioural and fMRI study. Neuropsychologia 44: 1230-1246.
42. Trimmel, M., Wittberger, S. (2004) Effects of transdermally administered nicotine on aspects of attention, task load, and mood in women and men. Pharmacol Biochem Behav 78: 639-645.
43. Vossel, S., Thiel, CM, Fink, GR (2008) Behavioral and neural effects of nicotine on visuospatial reorienting in non-smoking subjects. Neuropsychopharmacology 33: 731-738.
44. Wilson, BA, Cockburn, J., Halligan, P. (1987) Behavioural Inattention Test (BIT). Thames Valley Test Company. Hampshire: Titchfield.
45. Witte, EA, Davidson, MC, Marrocco, RT (1997) Effects of altering brain cholinergic activity on covert orienting of attention: comparison of monkey and human performance. Psychopharmacology 132: 324-334.
46. Zilles, K., Schleicher, A., Palomero-Gallagher, N., Amunts, K. (2002) Quantitative analysis of cyto- and receptorarchitecture of the human brain. In: Toga, AW, Mazziotta, JC (eds). Brain Mapping: The Methods. New York: Academic Press, pp. 573-602.
47. Zimmermann, P., Fimm, B. (1992) Testbatterie zur Aufmerksamkeitsprü fung (TAP). Freiburg: Psytest.