DNA damage in Mexican women with cervical dysplasia evaluated by comet assay

Analytical and Quantitative Cytology and Histology

Volumn 32, Issue 4, 2010, Pages 207-213

  Cortés Gutiérrez, Elva I ^a   Dávila Rodríguez, Martha I ^a   Zamudio González, Estela A ^a   Aguado Barrera, Miguel E ^a   Vargas Villarreal, Javier ^a   Cerda Flores, Ricardo M ^a,b  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

Author keywords

Cervical cancer; Cervical dysplasia; Comet assay; DNA; Electrophoresis

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COMET ASSAY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE SEVERITY; DNA DAMAGE; FEMALE; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; MEXICO; PRIORITY JOURNAL; UTERINE CERVIX DYSPLASIA; UTERINE CERVIX EPITHELIUM;

ADULT; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; COMET ASSAY; DNA DAMAGE; EPITHELIAL CELLS; FEMALE; GENOMIC INSTABILITY; HUMANS; MEXICO; MIDDLE AGED; NEOPLASM STAGING; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS; YOUNG ADULT;

EID: 77956214114     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Secretaria de Salud: Programa de prevención y control del cáncer cérvico uterino 1998-2000. Mexico, Secretaria de Salud, 1998
2. Solomon D, Schiffman M, Tarone R: Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: Baseline results from a randomized trial. J Natl Cancer Inst 2001;93:293-299 (Pubitemid 32219816)
3. Patten SF Jr: Diagnostic Cytology of the Uterine Cervix. Second edition. New York, S Karger, 1978
4. Herrington CS: Human papillomavirus and cervical neoplasia: I. Classification, virology, pathology, and epidemiology. J Clin Pathol 1994;44:1066-1072
5. Hsu TC, Cherry LM, Samaan NA: Differential mutagen susceptibility in cultured lymphocytes of normal individuals and cancer patients. Cancer Genet Cytogenet 1985;17:307-313
6. McKenna DJ, McKeown SR, McKelvey-Martin VJ: Potential use of the comet assay in the clinical management of cancer. Mutagenesis 2008;23:183-190
7. Valverde M, Rojas E: Environmental and occupational biomonitoring using the Comet assay. Mutat Res 2009;681:93-109
8. Jianlin L, Jiliang H, Lifen J, Wei Z, Baohong W, Hongping D: Measuring the genetic damage in cancer patients during radiotherapy with three genetic end-points. Mutagenesis 2004;19:457-464 (Pubitemid 39611595)
9. Mastaloudis A, Yu TW, O'Donnell RP, Frei B, Dashwood RH, Traber MG: Endurance exercise results in DNA damage as detected by the comet assay. Free Radic Biol Med 2004;36:966-975 (Pubitemid 38410803)
10. Schnurstein A, Braunbeck T: Tail moment versus tail length: Application of an in vitro version of the comet assay in bio-monitoring for genotoxicity in native surface waters using primary hepatocytes and gill cells from zebrafish (Danio rerio). Ecotoxicol Environ Saf 2001;49:187-196 (Pubitemid 32531168)
11. Anderson D, Yu TW, Wright J, Ioannides C: An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients. Mutat Res 1998;398:151-161 (Pubitemid 28225033)
12. Pitarque M, Creus A, Marcos R, Hughes JA, Anderson D: Examination of various biomarkers measuring genotoxic endpoints from Barcelona airport personnel. Mutat Res 1999;440:195-204 (Pubitemid 29168567)
13. Collins AR, Oscoz AA, Brunborg G, Gaiva I, Giovannelli L, Kruszewski M, Smith CC, Stetina R: The comet assay: Topical issues. Mutagenesis 2008;23:143-151
14. Kurman RJ, Solomon D (editors): Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnosis. New York, Springer, 1994
15. Creasman W: New gynecologic cancer staining. Obstet Gynecol 1990;75:287-288
16. Singh NP, McCoy MT, Tice RR, Schneider EL: A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191
17. Cortés-Gutiérrez EI, Cerda-Flores RM, Leal-Garza CH: Sister chromatid exchanges in peripheral lymphocytes from women with carcinoma of the uterine cervix. Cancer Genet Cytogenet 2000;15:121-123
18. Leal-Garza CH, Cerda-Flores RM, Leal-Elizondo E, Cortés- Gutiérrez EI: Micronuclei in cervical smears and peripheral blood lymphocytes from women with and without cervical uterine cancer. Mutat Res 2002;25:57-62
19. Udumudi A, Jaiswal M, Rajeswari N, Desai N, Jain S, Balakrishna N, Rao KV, Ahuja YR: Risk assessment in cervical dysplasia patients by single cell gel electrophoresis assay: A study of DNA damage and repair. Mutat Res 1998;30:195-205
20. Wilczynski SP, Walker J, Liao SY, Bergen S, Berman M: Adenocarcinoma of the cervix associated with human papillomavirus. Cancer 1988;62:1331-1336
21. Duensing S, Münger K: Mechanisms of genomic instability in human cancer: Insights from studies with human papillomavirus oncoproteins. Int J Cancer 2004;109:157-162
22. Popescu NC, Zimonjic D, Dipaolo JA: Viral integration, fragile sites and proto-oncogenes in human neoplasia. Hum Genet 1990;84:383-386
23. Sobti RC, Bhardwai DK, Gupta BD: Spontaneous chromosomal aberrations in peripheral blood lymphocytes of patients with cancer. Med Sci Res 1991;19:23-25
24. Atkin NB: Cytogenetics of carcinoma of the cervix uterine: A review. Cancer Genet Cytogenet 1997;95:33-39
25. Cortés-Gutiérrez EI, Dávila-Rodríguez MI, Muraira-Rodríguez M, Said-Fernández S, Cerda-Flores RM: Association between the stages of cervical cancer and chromosome 1 aneusomy. Cancer Genet Cytogenet 2005;159:44-47
26. Darzynkiewicz Z, Huang X, Okafuji M: Detection of DNA strand breaks by flow and laser scanning cytometry in studies of apoptosis and cell proliferation (DNA replication). Meth Mol Biol 2006;314:81-93
27. Ozkal P, Ilgin-Ruhi H, Akdogan M, Elhan AH, Kaçar S, Sasmaz N: The genotoxic effects of hepatitis B virus to host DNA. Mutagenesis 2005;20:147-150
28. Pan H, Zhou F, Gao SJ: Kaposi's sarcoma-associated herpesvirus induction of chromosome instability in primary human endothelial cells. Cancer Res 2004;64:4064-4068
29. Majone F, Luisetto R, Zamboni D, Iwanaga Y, Jeang KT: Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) tax target in clastogenic chromosomal instability of mammalian cells. Retrovirology 2005;2:45
30. Iarmarcovai G, Ceppi M, Botta A, Orsière T, Bonassi S: Micronuclei frequency in peripheral blood lymphocytes of cancer patients: A meta-analysis. Mutat Res 2008;659:274-283
31. Piyathilake CJ, Macaluso M, Brill I, Heimburger DC, Partridge EE: Lower red blood cell folate enhances the HPV-16- associated risk of cervical intraepithelial neoplasia. Nutrition 2007;23:203-210