Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Yamashita, Akihiro ^a   Nishikawa, Sandi ^a   Rancourt, Derrick E ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGENASE 3; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; BONE GROWTH; BONE REGENERATION; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; CELL LINEAGE; CHONDROGENESIS; CONTROLLED STUDY; DEVELOPMENT; DEVELOPMENTAL STAGE; EMBRYO; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION; HYPERTROPHY; MORPHOGENESIS; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL;

ANIMALS; BASE SEQUENCE; CALCIUM; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE; CHONDROCYTES; DNA PRIMERS; EMBRYONIC STEM CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOSAMINOGLYCANS; IN SITU NICK-END LABELING; MICE; MICROSCOPY, ELECTRON, SCANNING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 77956204475     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010998     Document Type: Article

References (26)

1. Quintana L, zur Nieden NI, Semino CE (2009) Morphogenetic and regulatory mechanisms during developmental chondrogenesis: new paradigms for cartilage tissue engineering. Tissue Eng Part B Rev 15: 29-41.
2. Goldring MB, Tsuchimochi K, Ijiri K (2006) The control of chondrogenesis. J Cell Biochem 97: 33-44.
3. Hegert C, Kramer J, Hargus G, Müller J, Guan K, et al. (2002) Differentiation plasticity of chondrocytes derived from mouse embryonic stem cells. J Cell Sci 115: 4617-28.
4. Kramer J, Hegert C, Guan K, Wobus AM, Müller PK, et al. (2000) Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4. Mech Dev 92: 193-205.
5. Nakayama N, Duryea D, Manoukian R, Chow G, Han CY (2003) Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells. J Cell Sci 16: 2015-28.
6. zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ (2005) Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages. BMC Dev Biol 5: 1.
7. Kramer J, Hegert C, Hargus G, Rohwedel J (2005) Mouse ES cell lines show a variable degree of chondrogenic differentiation in vitro. Cell Biol Int 29: 139-46.
8. Yamashita A, Krawetz R, Rancourt DE (2009) Loss of discordant cells during micro-mass differentiation of embryonic stem cells into the chondrocyte lineage. Cell Death Differ 16: 278-286.
9. Jukes JM, Both SK, Leusink A, Sterk LM, van Blitterswijk CA, et al. (2008) Endochondral bone tissue engineering using embryonic stem cells. Proc Natl Acad Sci USA 105: 6840-6845.
10. Hwang NS, Varghese S, Lee HJ, Zhang Z, Ye Z, et al. (2008) In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proc Natl Acad Sci USA 105: 20641-6.
11. Yamashita A, Nishikawa S, Rancourt DE (2010) Microenvironment modulates osteogenic cell lineage commitment in differentiated embryonic stem cell. PLos One 5: e9663.
12. Yamashita A, Takada T, Kanbe-Omatsu M, Nemoto K, Matsuura H, et al. (2006) Monkey embryonic stem cells differentiate into adipocytes in vitro. Cloning Stem Cells 8: 3-9.
13. Yamashita A, Takada T, Nemoto K, Yamamoto G, Torii R (2006) Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage. FEBS Lett 580: 4121-4125.
14. Kino-Oka M, Yashiki S, Ota Y, Mushiaki Y, Sugawara K, et al. (2005) Subculture of chondrocytes on a collagen type I-coated substrate with suppressed cellular dedifferentiation. Tissue Eng 11: 597-608.
15. Wescoe KE, Schugar RC, Chu CR, Deasy BM (2008) The role of the biochemical and biophysical environment in chondrogenic stem cell differentiation assays and cartilage tissue engineering. Cell Biochem Biophys 52: 85-102.
16. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, et al. (2000) Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med 6: 88-95.
17. Keller GM (1995) In-vitro differentiation of embryonic stem cells. Curr Opin Cell Biol 7: 862-869.
18. Hwang NS, Varghese S, Elisseeff J (2008) Derivation of chondrogenically-committed cells from human embryonic cells for cartilage tissue regeneration. PLoS One 3: e2498.
19. Ofek G, Revell CM, Hu JC, Allison DD, Grande-Allen KJ, et al. (2008) Matrix development in self-assembly of articular cartilage. PLoS One 3: e2795.
20. Elder BD, Athanasiou KA (2008) Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation. PLoS One 3: e2341.
21. Sugiki T, Uyama T, Toyoda M, Morioka H, Kume S, et al. (2007) Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts. J Cell Biochem 100: 1240-1254.
22. Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, et al. (1997) SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol. Mar 183: 108-21.
23. Hoffman LM, Weston AD, Underhill TM (2003) Molecular mechanisms regulating chondroblast differentiation. J Bone Joint Surg Am 85-A: Suppl 2124-32.
24. James CG, Stanton LA, Agoston H, Ulici V, Underhill TM, et al. (2010) Genome-wide analyses of gene expression during mouse endochondral ossification. PLoS One 5: e8693.
25. Mackie EJ, Ahmed YA, Tatarczuch L, Chen KS, Mirams M (2008) Endochondral ossification: how cartilage is converted into bone in the developing skeleton. Int J Biochem Cell Biol 40: 46-62.
26. Chan CK, Chen CC, Luppen CA, Kim JB, DeBoer AT, et al. (2009) Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature 457: 490-494.