New route for synthesizing poly(ethylene glycol)-acrylic acid hydrogels using γ-irradiation for drug delivery carriers

Biotechnology and Bioprocess Engineering

Volumn 15, Issue 3, 2010, Pages 392-399

  Gwon, Hui Jeong ^a,b   Lim, Youn Mook ^a   Nho, Young Chang ^a   Shim, Jae Woon ^c   Kwon, Il Keun ^d   Chang, Ho Nam ^b   Kim, Sung Eun ^d  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Korea Institute of Energy Research (KIER)   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

Acrylic acid; Drug delivery; Insulin; Irradiation; Poly(ethylene glycol)

Indexed keywords

ACIDIC MEDIA; ACRYLIC ACIDS; BASIC CONDITIONS; BLOOD GLUCOSE; DIABETIC RATS; DRUG DELIVERY CARRIER; EQUILIBRIUM SWELLING; GEL FRACTION; HIGH PH; INSULIN RELEASE; INTERPOLYMER COMPLEXES; ORAL DRUG DELIVERY; PH-RESPONSIVE; RAPID RELEASE; REDUCTION EFFECTS;

BLOOD; CARBOXYLIC ACIDS; CONTROLLED DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; GELS; GLUCOSE; INSULIN; IRRADIATION; ORGANIC ACIDS; PH EFFECTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SWELLING;

HYDROGELS;

ACRYLIC ACID; GLUCOSE; INSULIN; MACROGOL; STREPTOZOCIN;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; GAMMA IRRADIATION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR INTERACTION; NONHUMAN; PH; PHYSICAL CHEMISTRY; RAT; STREPTOZOCIN DIABETES; SYNTHESIS;

RATTUS;

EID: 77956202925     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12257-009-3044-x     Document Type: Article

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