Transition-metal-free sonogashira-type coupling of ortho-substituted aryl and alkynyl grignard reagents by using 2,2,6,6-tetramethylpiperidine-N-oxyl radical as an oxidant

Organic Letters

Volumn 12, Issue 17, 2010, Pages 3878-3881

  Maji, Modhu Sudan ^a   Murarka, Sandip ^a   Studer, Armido ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956195808     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol1015702     Document Type: Article

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36. Reaction did not work on the corresponding methyl esters and for the aryl-Mg derivative derived from 4-iodo-3,5-dimethylphenylpivalate. This is probably due to the instability of the corresponding Ar-Mg species at room temperature.