Roscovitine-based CDK inhibitors acting as N-donor ligands in the platinum(II) oxalato complexes: Preparation, characterization and in vitro cytotoxicity

European Journal of Medicinal Chemistry

Volumn 45, Issue 10, 2010, Pages 4609-4614

  Trávníček, Zdeněk ^a   Štarha, Pavel ^a   Popa, Igor ^a   Vrzal, Radim ^a   Dvořák, Zdeněk ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

CDK inhibitors; Cytotoxicity; Multinuclear NMR; Oxalate; Platinum(II) complexes

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR; OXALIPLATIN; PLATINUM OXALATE 2 (1 ETHYL 2 HYDROXYETHYLAMINO) N6 (2 METHOXYBENZYL) 9 ISOPROPYLADENINE WATER COMPLEX; PLATINUM OXALATE 2 (1 ETHYL 2 HYDROXYETHYLAMINO) N6 (3 METHOXYBENZYL) 9 ISOPROPYLADENINE WATER COMPLEX; PLATINUM OXALATE 2 (1 ETHYL 2 HYDROXYETHYLAMINO) N6 (4 METHOXYBENZYL) 9 ISOPROPYLADENINE WATER COMPLEX; PLATINUM OXALATE 2 (1 ETHYL 2 HYDROXYETHYLAMINO) N6 (BENZYL) 9 ISOPROPYLADENINE WATER COMPLEX; ROSCOVITINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DETERMINATION; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAMAN SPECTROMETRY; SUBSTITUTION REACTION; THERMAL ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASES; HEPATOCYTES; HUMANS; NEOPLASMS; ORGANOPLATINUM COMPOUNDS; OXALATES; PROTEIN KINASE INHIBITORS; PURINES; SPECTRUM ANALYSIS;

EID: 77956187622     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.025     Document Type: Article

References (20)

1. P.J. Davies Plant Hormones third ed. 1997 Springer Dordrecht
2. L. Meijer, A. Borgne, O. Mulner, J.P.J. Chong, J.J. Blow, N. Inagaki, M. Inagaki, J.G. Delcros, and J.P. Moulinoux Eur. J. Biochem. 243 1997 527 536
3. C. Benson, S. Kaye, P. Workman, M. Garret, M. Walton, and J. de Bono Br. J. Cancer 92 2005 7 12
4. P. tarha, Z. Trávníek, R. Herchel, I. Popa, P. Suchý, and J. Vano J. Inorg. Biochem. 103 2009 432 440
5. Z. Trávníek, and J. Marek J. Mol. Struct. 933 2010 148 155
6. Z. Trávníek, I. Popa, M. ajan, R. Zboil, V. Krytof, and J. Mikulík J. Inorg. Biochem. 104 2010 405 417
7. P. tarha, I. Popa, and Z. Trávníek Inorg. Chim. Acta 363 2010 1469 1478
8. P. tarha, Z. Trávníek, and I. Popa J. Inorg. Biochem. 104 2010 639 647
9. M. Malo, Z. Trávníek, R. Marek, and M. Strnad J. Inorg. Biochem. 99 2005 2127 2138
10. M.J. Cleare Coord. Chem. Rev. 12 1974 349 405
11. E. Monti, M. Gariboldi, A. Maiocchi, E. Marengo, C. Cassino, E. Gabano, and D.J. Osella J. Med. Chem. 48 2005 857 866
12. W.J. Geary Coord. Chem. Rev. 7 1971 81 122
13. K. Nakamoto Infrared and Raman Spectra of Inorganic and Coordination Compounds fifth ed. 1997 Willey-Interscience New York
14. C.J. Pouchert The Aldrich Library of Infrared Spectra third ed. 1981 Aldrich Chemical Co. Milwaukee
15. T.A. Mohamed, I.A. Shabaan, W.M. Zoghaib, J. Husband, R.S. Farag, and A.E.M.A. Alajhaz J. Mol. Struct. 938 2009 263 276
16. V. Montoya, J. Pons, J. García-Antón, X. Solans, M. Font-Bardia, and J. Ros Inorg. Chim. Acta 360 2007 625 637
17. Z. Dhaouadi, M. Ghomi, J.C. Austin, R.B. Girling, R.E. Hester, P. Mojzes, L. Chinsky, P.Y. Turpin, C. Coulombeau, H. Jobic, and J. Tomkinson J. Phys. Chem. 97 1993 1074 1084
18. L.R. Kelland, and N.P. Farrell Platinum Based Drugs in Cancer Therapy 2000 Humana Press Totowa, New Jersey
19. J. Ulrichová, Z. Dvoák, J. Viar, J. Lata, J. Smrová, A. edo, and V. imánek Toxicol. Lett. 125 2001 125 132
20. L. Pichard-Garcia, S. Gerbal-Chaloin, J.B. Ferrini, J.M. Fabre, and P. Maurel Meth. Enzymol. 357 2002 311 321