Platinum(II) oxalato complexes with adenine-based carrier ligands showing significant in vitro antitumor activity

Journal of Inorganic Biochemistry

Volumn 104, Issue 6, 2010, Pages 639-647

  Štarha, Pavel ^a   Trávnícek, Zdenek ^a   Popa, Igor ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Adenine derivatives; Crystal structures; In vitro cytotoxicity; Oxalate; Platinum(II) complexes

Indexed keywords

ADENINE DERIVATIVE; ANTINEOPLASTIC AGENT; CISPLATIN; COORDINATION COMPOUND; DRUG CARRIER; LIGAND; N,N DIMETHYLFORMAMIDE; OXALIPLATIN; PLATINUM 2 CHLORO N6 (2 METHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (2,3 DIMETHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (2,4 DIMETHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (3 METHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (3,4 DIMETHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (3,5 DIMETHOXYBENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM 2 CHLORO N6 (BENZYL) 9 ISOPROPYLADENINE OXALATO COMPLEX; PLATINUM COMPLEX; PLATINUM OXALATO COMPLEX; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CARCINOMA CELL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; OSTEOSARCOMA; SARCOMA CELL;

ADENINE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; ORGANOPLATINUM COMPOUNDS;

EID: 77952545312     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2010.02.005     Document Type: Article

References (35)

1. Kelland L.R., Farrell N.P. Platinum Based Drugs in Cancer Therapy 2000, Humana Press, Totowa, New Jersey.
2. Gielen M., Tiekink E.R.T. Metallotherapeutic Drugs and Metal-based Diagnostic Agents 2005, London, Willey.
3. Pasetto L.M., D'Andrea M.R., Brandes A.A., Rossi E., Monfardini S. Crit. Rev. Oncol. Hemat. 2006, 60:59-75.
4. Kidani Y., Inagaki K. J. Med. Chem. 1978, 21:1315-1318.
5. Habala L., Galanski M., Yasemi A., Nazarov A.A., von Keyserlingk N.G., Keppler B.K. Eur. J. Med. Chem. 2005, 40:1149-1155.
6. Abu-Surrah A.S., Kettunen M., Leskela M., Al-Abed Y.Z. Anorg. Allg. Chem. 2008, 634:2655-2658.
7. Yu Y., Lou L.G., Liu W.P., Zhu H.J., Ye Q.S., Chen X.Z., Gao W.G., Hou S.Q. Eur. J. Med. Chem. 2008, 43:1438-1443.
8. Bowler B.E., Ahmed K.J., Sundquist W.I., Hollis L.S., Whang E.E., Lippard S.J. J. Am. Chem. Soc. 1989, 111:1299-1306.
9. Sen V.D., Golubev V.A., Volkova L.M., Konovalova N.P. J. Inorg. Biochem. 1996, 64:69-77.
10. Mukhopadhyay U., Thurston J., Whitmire K.H., Siddik Z.H., Khokhar A.R. J. Inorg. Biochem. 2003, 94:179-185.
11. Meelich K., Galanski M., Arion V.B., Keppler B.K. Eur. J. Inorg. Chem. 2006, 2476-2483.
12. Chen X.Z., Xie M.J., Liu W.P., Ye Q.S., Yu Y., Hou S.Q., Gao W.G., Liu Y. Inorg. Chim. Acta 2007, 360:2851-2856.
13. Chen X.Z., Ye O.S., Lou L.G., Xie M.J., Liu W.P., Yu Y., Hou S.Q. Arch. Pharm. 2008, 341:132-136.
14. Allen F.A. Acta Crystallogr., Sect. B: Struct. Sci. 2002, 58:380-388.
15. Cleare M.J. Coord. Chem. Rev. 1974, 12:349-405.
16. Monti E., Gariboldi M., Maiocchi A., Marengo E., Cassino C., Gabano E., Osella D.J. J. Med. Chem. 2005, 48:857-866.
17. Liu W., Chen X., Xie M., Lou L., Ye Q., Hou S. J. Inorg. Biochem. 2008, 102:1942-1946.
18. Dolfen D., Schottler K., Valiahdi S.M., Jakupec M.A., Keppler B.K., Tiekink E.R.T., Mohr F. J. Inorg. Biochem. 2008, 102:2067-2071.
19. Diakos C.I., Zhang M., Beale P.J., Fenton R.R., Hambley T.W. Eur. J. Med. Chem. 2009, 44:2807-2814.
20. Hegmans A., Kasparkova J., Vrana O., Kelland L.R., Brabec V., Farrell N.P. J. Med. Chem. 2008, 51:2254-2260.
21. Szücová L., Trávnícek Z., Popa I., Marek J. Polyhedron 2008, 27:2710-2720.
22. Trávnícek Z., Popa I., cajan M., Herchel R., Marek J. Polyhedron 2007, 26:5271-5282.
23. Malon M., Trávnícek Z., Marek R., Strnad M. J. Inorg. Biochem. 2005, 99:2127-2138.
24. Meijer L., Borgne A., Mulner O., Chong J.P.J., Blow J.J., Inagaki N., Inagaki M., Delcros J.G., Moulinoux J.P. Eur. J. Biochem. 1997, 243:527-536.
25. Oh C.H., Lee S.C., Lee K.S., Woo E.R., Hong C.Y., Yang B.S., Baek D.J., Cho J.H. Arch. Pharm. Pharm. Med. Chem. 1999, 332:187-190.
26. CrysAlis RED, CrysAlis CCD Version 1.171.32.11 2006, Oxford Diffraction Ltd., Abingdon, England.
27. Sheldrick G.M. Acta Cryst. 2008, A64:112-122.
28. K. Brandenburg, DIAMOND, Release 3.1f, Crystal Impact GbR, Bonn: Germany, 2006.
29. Krogmann K., Dodel P. Chem. Ber. Recl. 1966, 99:3402-3408.
30. Geary W.J. Coord. Chem. Rev. 1971, 7:81-122.
31. Ali M.S., Thurston J.H., Whitmire K.H., Khokhar A.R. Polyhedron 2002, 21:2659-2665.
32. Khan S.R.A., Guzman-Jimenez I., Whitmire K.H., Khokhar A.R. Polyhedron 2000, 19:975-981.
33. Khan S.R.A., Guzman-Jimenez I., Whitmire K.H., Khokhar A.R. Polyhedron 2000, 19:983-989.
34. Nakamoto K. Infrared and Raman Spectra of Inorganic and Coordination Compounds 1997, Willey-Interscience, New York. 5th ed.
35. Dhaouadi Z., Ghomi M., Austin J.C., Girling R.B., Hester R.E., Mojzes P., Chinsky L., Turpin P.Y., Coulombeau C., Jobic H., Tomkinson J. J. Phys. Chem. 1993, 97:1074-1084.