Docking to erlotinib off-targets leads to inhibitors of lung cancer cell proliferation with suitable in vitro pharmacokinetics

ACS Medicinal Chemistry Letters

Volumn 1, Issue 5, 2010, Pages 229-233

  Li, Liwei ^a   Li, Jing ^a   Khanna, May ^a   Jo, Inha ^a   Baird, Jason P ^a   Meroueh, Samy O ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; MENOGARIL; POTASSIUM CHANNEL HERG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENCY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG CANCER; LYMPHOMA; MOLECULAR DOCKING; MOLECULAR LIBRARY; PHARMACOPHORE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUPPORT VECTOR MACHINE;

EID: 77956166424     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100031a     Document Type: Article

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