Colorectal carcinoma cells-Regulation of survival and growth by SGK1

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 10, 2010, Pages 1571-1575

  Lang, Florian ^a   Perrotti, Nicola ^b   Stournaras, Christos ^c  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c UNIVERSITY OF CRETE   (Greece)

Author keywords

Ion channels; P53; PI3 kinase pathway

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ION CHANNEL; PROTEIN KINASE B; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; TRANSCRIPTION FACTOR FKHRL1;

CANCER CELL CULTURE; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CARCINOMA; DOWN REGULATION; HUMAN; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; SHORT SURVEY; STOMACH MOTILITY; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; ENZYME INHIBITORS; HUMANS; IMMEDIATE-EARLY PROTEINS; MALE; MICE; MICE, KNOCKOUT; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

MUS;

EID: 77956140003     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.05.016     Document Type: Short Survey

References (34)

1. Amato R., D'Antona L., Porciatti G., Agosti V., Menniti M., Rinaldo C., Costa N., Bellacchio E., Mattarocci S., Fuiano G., Soddu S., Paggi M.G., Lang F., Perrotti N. Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation. J Mol Med 2009, 87:1221-1239.
2. Amato R., Menniti M., Agosti V., Boito R., Costa N., Bond H.M., Barbieri V., Tagliaferri P., Venuta S., Perrotti N. IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells. J Mol Med 2007, 85:707-721.
3. Boehmer C., Laufer J., Jeyaraj S., Klaus F., Lindner R., Lang F., Palmada M. Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination. Cell Physiol Biochem 2008, 22:591-600.
4. Boehmer C., Palmada M., Klaus F., Jeyaraj S., Lindner R., Laufer J., Daniel H., Lang F. The peptide transporter PEPT2 is targeted by the protein kinase SGK1 and the scaffold protein NHERF2. Cell Physiol Biochem 2008, 22:705-714.
5. Boiteux A., Hess B. Design of glycolysis. Philos Trans R Soc Lond B: Biol Sci 1981, 293:5-22.
6. Dehner M., Hadjihannas M., Weiske J., Huber O., Behrens J. Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1. J Biol Chem 2008, 283:19201-19210.
7. Gehring E.M., Zurn A., Klaus F., Laufer J., Sopjani M., Lindner R., Strutz-Seebohm N., Tavare J.M., Boehmer C., Palmada M., Lang U.E., Seebohm G., Lang F. Regulation of the glutamate transporter EAAT2 by PIKfyve. Cell Physiol Biochem 2009, 24:361-368.
8. Gu S., Papadopoulou N., Gehring E.M., Nasir O., Dimas K., Bhavsar S.K., Foller M., Alevizopoulos K., Lang F., Stournaras C. Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo. Mol Cancer 2009, 8:114.
9. Krueger B., Haerteis S., Yang L., Hartner A., Rauh R., Korbmacher C., Diakov A. Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1. Cell Physiol Biochem 2009, 24:605-618.
10. Lang F., Artunc F., Vallon V. The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens 2009, 18:439-448.
11. Lang F., Bohmer C., Palmada M., Seebohm G., Strutz-Seebohm N., Vallon V. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev 2006, 86:1151-1178.
12. Laufer J., Boehmer C., Jeyaraj S., Knuwer M., Klaus F., Lindner R., Palmada M., Lang F. The C-terminal PDZ-binding motif in the Kv1.5 potassium channel governs its modulation by the Na+/H+ exchanger regulatory factor 2. Cell Physiol Biochem 2009, 23:25-36.
13. Markowitz S.D., Bertagnolli M.M. Molecular origins of cancer: molecular basis of colorectal cancer. N Engl J Med 2009, 361:2449-2460.
14. Melhem A., Yamada S.D., Fleming G.F., Delgado B., Brickley D.R., Wu W., Kocherginsky M., Conzen S.D. Administration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissues. Clin Cancer Res 2009, 15:3196-3204.
15. Nasir O., Wang K., Foller M., Gu S., Bhandaru M., Ackermann T.F., Boini K.M., Mack A., Klingel K., Amato R., Perrotti N., Kuhl D., Behrens J., Stournaras C., Lang F. Relative resistance of SGK1 knockout mice against chemical carcinogenesis. IUBMB Life 2009, 61:768-776.
16. Papadopoulou N., Charalampopoulos I., Anagnostopoulou V., Konstantinidis G., Foller M., Gravanis A., Alevizopoulos K., Lang F., Stournaras C. Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells. Mol Cancer 2008, 7:88.
17. Peterson T.R., Laplante M., Thoreen C.C., Sancak Y., Kang S.A., Kuehl W.M., Gray N.S., Sabatini D.M. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 2009, 137:873-886.
18. Rotte A., Bhandaru M., Foller M., Biswas R., Mack A.F., Friedrich B., Rexhepaj R., Nasir O., Ackermann T.F., Boini K.M., Kunzelmann K., Behrens J., Lang F. APC sensitive gastric acid secretion. Cell Physiol Biochem 2009, 23:133-142.
19. Roulin D., Cerantola Y., Dormond-Meuwly A., Demartines N., Dormond O. Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo. Mol Cancer 2010, 9:57.
20. Rusai K., Wagner B., Roos M., Schmaderer C., Strobl M., Boini K.M., Grenz A., Kuhl D., Heemann U., Lang F., Lutz J. The serum and glucocorticoid-regulated kinase 1 in hypoxic renal injury. Cell Physiol Biochem 2009, 24:577-584.
21. Salmena L., Carracedo A., Pandolfi P.P. Tenets of PTEN tumor suppression. Cell 2008, 133:403-414.
22. Segditsas S., Sieber O., Deheragoda M., East P., Rowan A., Jeffery R., Nye E., Clark S., Spencer-Dene B., Stamp G., Poulsom R., Suraweera N., Silver A., Ilyas M., Tomlinson I. Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice. Hum Mol Genet 2008, 17:3864-3875.
23. Shanmugam I., Cheng G., Terranova P.F., Thrasher J.B., Thomas C.P., Li B. Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival. Cell Death Differ 2007, 14:2085-2094.
24. Sherk A.B., Frigo D.E., Schnackenberg C.G., Bray J.D., Laping N.J., Trizna W., Hammond M., Patterson J.R., Thompson S.K., Kazmin D., Norris J.D., McDonnell D.P. Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic. Cancer Res 2008, 68:7475-7483.
25. Sopjani M., Kunert A., Czarkowski K., Klaus F., Laufer J., Foller M., Lang F. Regulation of the Ca(2+) channel TRPV6 by the Kinases SGK1, PKB/Akt, and PIKfyve. J Membr Biol 2010, 233:35-41.
26. Soundararajan R., Melters D., Shih I.C., Wang J., Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex. Proc Natl Acad Sci U S A 2009, 106:7804-7809.
27. Steelman L.S., Abrams S.L., Whelan J., Bertrand F.E., Ludwig D.E., Basecke J., Libra M., Stivala F., Milella M., Tafuri A., Lunghi P., Bonati A., Martelli A.M., McCubrey J.A. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 2008, 22:686-707.
28. Wang K., Gu S., Nasir O., Foller M., Ackermann T.F., Klingel K., Kandolf R., Kuhl D., Stournaras C., Lang F. SGK1-dependent intestinal tumor growth in APC-deficient mice. Cell Physiol Biochem 2010, 25:271-278.
29. Wang W.S., Chen P.M., Su Y. Colorectal carcinoma: from tumorigenesis to treatment. Cell Mol Life Sci 2006, 63:663-671.
30. Won M., Park K.A., Byun H.S., Kim Y.R., Choi B.L., Hong J.H., Park J., Seok J.H., Lee Y.H., Cho C.H., Song I.S., Kim Y.K., Shen H.M., Hur G.M. Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration. J Hepatol 2009, 51:67-76.
31. Yoon J.W., Gilbertson R., Iannaccone S., Iannaccone P., Walterhouse D. Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes. Int J Cancer 2009, 124:109-119.
32. Zhang L., Cui R., Cheng X., Du J. Antiapoptotic effect of serum and glucocorticoid-inducible protein kinase is mediated by novel mechanism activating I{kappa}B kinase. Cancer Res 2005, 65:457-464.
33. Zhao L., Vogt P.K. Class I PI3K in oncogenic cellular transformation. Oncogene 2008, 27:5486-5496.
34. Zou J.X., Guo L., Revenko A.S., Tepper C.G., Gemo A.T., Kung H.J., Chen H.W. Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Res 2009, 69:3339-3346.