Improving quinolone use in hospitals by using a bundle of interventions in an interrupted time series analysis

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 9, 2010, Pages 3763-3769

  Willemsen, Ina ^a   Cooper, Ben ^b   Van Buitenen, Carin ^a   Winters, Marjolein ^a   Andriesse, Gunnar ^a   Kluytmans, Jan ^a,c  

^a AMPHIA HOSPITAL   (Netherlands)

^b MAHIDOL UNIVERSITY   (Thailand)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; CEFUROXIME; CIPROFLOXACIN; COTRIMOXAZOLE; TOBRAMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; COST CONTROL; DRUG COST; DRUG MONITORING; EDUCATION PROGRAM; ESCHERICHIA COLI; HOSPITAL INFECTION; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; POISSON DISTRIBUTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; TIME SERIES ANALYSIS;

ANTI-BACTERIAL AGENTS; CIPROFLOXACIN; HOSPITALS; HUMANS; INJECTIONS, INTRAVENOUS; PROSPECTIVE STUDIES; QUINOLONES;

EID: 77956119609     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01581-09     Document Type: Article

References (33)

1. Beaber, J. W., B. Hochhut, and M. K. Waldor. 2004. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427:72-74.
2. Bruinsma, N., P. M. G. Filius, A. E. van den Bogaard, S. Nys, J. Degener, H. P. Endtz, and E. E. Stobberingh. 2003. Hospitalization, a risk factor for antibiotic-resistant Escherichia coli in the community? J. Antimicrob. Chemother. 51:1029-1032.
3. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing: 15th information supplement. M100-S15. Clinical and Laboratory Standards Institute, Wayne, PA.
4. Cohn, S. M., P. A. Lipsett, T. G. Buchman, W. G. Cheaddle, J. W. Milson, S. O'Marro, A. E. Yellin, S. Jungerwirth, E. V. Rochfort, D. C. Haverstock, and S. F. Kowalsky. 2000. Comparison of intravenous/oral ciprofloxacin plus metronidazole versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections. Ann. Surg. 232:254-262.
5. de Marie, S., M. F. VandenBergh, S. L. Buijk, H. A. Bruining, A. van Vliet, J. A. Kluytmans, and J. W. Moutonn. 1998. Bioavailability of ciprofloxacin after multiple enteral and intravenous doses in ICU patients with severe gram-negative intra-abdominal infections. Intensive Care Med. 24:343-346.
6. Dutch Working Party on Antibiotic Policy (SWAB). 2008. Nethmap 2008. http: //www.swab.nl/swab/swabcms.nsf/(WebFiles)/E32F6709B7DB7F2EC125744F002A CAA5/$FILE/NethMap-2008.pdf.
7. Enne, V. I., D. M. Livermore, P. Stephens, and L. M. Hall. 2001. Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction. Lancet 357:1325-1328.
8. European Antimicrobial Resistance Surveillance System. 2007. Annual report. http: //www.rivm.nl/earss/Images/EARSS%202007-FINAL-tcm61-55933.pdf.
9. Goossens, H., M. Ferech, R. Vander Stichele, M. Elseviers, and ESAC Project Group. 2005. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 365:548-549.
10. Hamilton-Miller, J. M. T. 1996. Switch therapy: the theory and practice of early change from parenteral to non-parenteral route. Clin. Infect. Dis. 2:12-19.
11. Harbarth, S., A. Harris, Y. Carmeli, and M. Samore. 2001. Parallel analysis of individual and aggregated data on antibiotic exposure and resistance in Gram-negative bacilli. Clin. Infect. Dis. 33:1462-1468.
12. Hoeting, J. A., D. Madigan, A. E. Raftery, and C. T. Volinsky. 1999. Bayesian model averaging: a tutorial. Statist. Sci. 14:382-417.
13. Lipsitch, M. 2001. The rise and fall of antimicrobial resistance. Trends Microbiol. 9:438-444.
14. Lipsitch, M., C. T. Bergstrom, and B. R. Levin. 2000. The epidemiology of antibiotic resistance in hospitals: paradoxes and prescriptions. Proc. Natl. Acad. Sci. U. S. A. 97:1938-1943.
15. Lipsitch, M., and M. H. Samore. 2002. Antimicrobial use and antimicrobial resistance: a population perspective. Emerg. Infect. Dis. 8:347-354.
16. MacDougall, C., and R. E. Polk. 2008. Variability in rates of use of antibacterials among 130 US hospitals and risk-adjustment models for interhospital comparision. Infect. Control Hosp. Epidemiol. 29:203-211.
17. Mandell, L. A., M. G. Bergeron, M. J. Gribble, P. J. Jeweson, D. E. Low, T. J. Marie, and L. E. Nicolle. 1995. Sequential antibiotic therapy: effective cost management and patient care. Can. J. Infect. Dis. 6:306-315.
18. Polk, R. E. 1989. Drug-drug interactions with ciprofloxacin and other fluoroquinolones. Am. J. Med. 87(Suppl. 5A):76S-81S.
19. Prins, J. M., B. J. Kullberg, and I. C. Gyssens. 2005. National guidelines for the use of antibiotics in hospitalised adult patients: the SWAB guidelines revisited. Neth. J. Med. 63:323-335.
20. Ramsay, C., E. Brown, G. Hartman, and P. Davey on behalf of the joint BSAC/HIS Working Party on Optimization of Antibiotic Prescribing in Hospitals. 2003. Room for improvement: a systematic review of the quality of evaluation of interventions to improve hospital antibiotic prescribing. J. Antimicrob. Chemother. 52:764-771.
21. Ramsay, C. L., L. Matowe, R. Grilli, J. M. Grimshaw, and R. E. Thomas. 2003. Interrupted time series designs in health technology assessment: lessons from two systematic reviews of behavior change strategies. Int. J. Technol. Assess. Health Care 19:613-623.
22. R Development Core Team. 2009. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
23. Seppala, H., T. Klaukka, J. Vuopio-Varkila, A. Muotiala, H. Helenius, K. Lager, and P. Huovinen. 1997. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. Finnish Study Group for Antimicrobial Resistance. N. Engl. J. Med. 337:441-446.
24. Sevinç, F., J. M. Prins, R. P. Koopmans, P. N. J. Langendijk, P. M. M. Bossuyt, J. Dankert, and P. Speelman. 1999. Early switch from intravenous to oral antibiotics: guidelines and implementation in a large teaching hospital. J. Antimicrob. Chemother. 43:601-606.
25. Spellberg, B., R. Guidos, D. Gilbert, D. J. Bradley, H. W. Boucher, W. N. M. Scheld, J. G. Bartlett, and J. U. Edwards, Jr., for the Infectious Diseases Society of America. 2008. The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin. Infect. Dis. 46:155-164.
26. StataCorp. 2007. Stata statistical software: release 10. StataCorp LP, College Station, TX.
27. Vander Stichele, R. H., M. M. Elseviers, M. Ferech, S. Blot, and H. Goossens on behalf of the European Surveillance of Antibiotic Consumption (ESAC) Project Group. 2006. Hospital consumption of antibiotics in 15 European countries: results of the ESAC Retrospective Data Collection (1997-2002). J. Antimicrob. Chemother. 58:900-901.
28. Van Eldere, J., R. M. Mera, L. A. Miller, J. A. Poupard, and H. Amrine-Madsen. 2007. Risk factors for development of multiple-class resistance to Streptococcus pneumoniae strains in Belgium over a 10-year period: antimicrobial consumption, population density, and geographic location. Antimicrob. Agents Chemother. 51:3491-3497.
29. Van Hees, B. C., E. de Ruiter, E. H. Wiltink, B. M. de Jongh, and M. Tersmette. 2008. Optimizing use of ciprofloxacin: a prospective intervention study. J. Antimicrob. Chemother. 61:210-213.
30. Willemsen, I., A. Groenhuijzen, D. Bogaers, A. Stuurman, P. van Keulen, and J. Kluytmans. 2007. Appropriateness of antimicrobial therapy measured by repeated prevalence surveys. Antimicrob. Agents Chemother. 51:864-867.
31. Willemsen, I., D. Bogaers-Hofman, M. Winters, and J. Kluytmans. 2009. Correlation between antibiotic use and resistance in a hospital: temporary and ward specific observations. Infection 37:432-437.
32. Willemsen, I., M. Mooij, M. van der Wiel, D. Bogaers, M. van der Bijl, P. Savelkoul, and J. Kluytmans. 2008. Highly resistant microorganisms in a teaching hospital: the role of horizontal spread in a setting of endemicity. Infect. Control Hosp. Epidemiol. 29:1110-1117.
33. World Health Organization. 2002. Guidelines for ATC classification and DDD assignment. WHO Collaborating Centre for Drug Statistics Methology. Norwegian Institute of Public Health, Oslo, Norway.