Gemcitabine resistance induced by interaction between alternatively spliced segment of Tenascin-C and Annexin A2 in pancreatic cancer cells

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 8, 2010, Pages 1261-1267

  Gong, Xiao Guang ^a   Lv, Yun Fu ^a,b   Li, Xin Qiu ^a   Xu, Fu Guo ^a   Ma, Qing Yong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b Department of General Surgery   (Taiwan)

Author keywords

Annexin A2; Drug resistance; Gemcitabine; Pancreatic cancer; Tenascin C

Indexed keywords

GEMCITABINE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; LIPOCORTIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PYRROLIDINE DITHIOCARBAMATE; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TENASCIN; TRANSCRIPTION FACTOR RELA;

ADULT; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL SURFACE; CONCENTRATION PROCESS; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; FEMALE; GENE ACTIVATION; GENE FUNCTION; GENE INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; SIGNAL TRANSDUCTION;

ALTERNATIVE SPLICING; ANNEXIN A2; ANTIMETABOLITES, ANTINEOPLASTIC; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYCYTIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HUMANS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TENASCIN; TRANSCRIPTION FACTOR RELA;

EID: 77956109840     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.1261     Document Type: Article

References (23)

1. Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., Thun M. J., CA Cancer J. Clin., 58, 71-96 (2008).
2. Heinemann V., Oncology, 60, 8-18 (2001).
3. Rengifo-Cam W., Umar S., Sarkar S., Singh P., Cancer Res., 15, 7266-7274 (2007).
4. Cockrell E., Espinola R. G., McCrae K. R., Lupus, 17, 943-951 (2008).
5. Morel E., Gruenberg J., J. Biol. Chem., 284, 1604-1611 (2009).
6. Zhou H., Ling S., Yu Y., Wang T., Hu H., Cell. Res., 17, 737-739 (2007).
7. Vishwanatha J. K., Chiang Y., Kumble K. D., Hollingsworth M. A., Pour P. M., Carcinogenesis, 14, 2575-2579 (1993).
8. Takano S., Togawa A., Yoshitomi H., Shida T., Kimura F., Shimizu H., Yoshidome H., Ohtsuka M., Kato A., Tomonaga T., Nomura F., Miyazaki M., Ann. Surg. Oncol., 15, 3157-3168 (2008).
9. Chung C. Y., Erickson H. P., J. Cell. Biol., 126, 539-548 (1994).
10. Brellier F., Tucker R. P., Chiquet-Ehrismann R., Scand. J. Med. Sci. Sports, 19, 511-519 (2009).
11. Chiquet-Ehrismann R., Int. J. Biochem. Cell. Biol., 36, 986-990 (2004).
12. Esposito I., Penzel R., Chaib-Harrireche M., Barcena U., Bergmann F., Riedl S., Kayed H., Giese N., Kleeff J., Friess H., Schirmacher P., J. Pathol., 208, 673-685 (2006).
13. Chen J., Chen Z., Chen M., Li D., Li Z., Xiong Y., Dong J., Li X., Int. J. Oncol., 34, 1029-1036 (2009).
14. Emoto K., Yamada Y., Sawada H., Fujimoto H., Ueno M., Takayama T., Kamada K., Naito A., Hirao S., Nakajima Y., Cancer, 92, 1419-1426 (2001).
15. Wang Y. C., Zheng L. H., Ma B. A., Zhou Y., Fan Q. Y., Hybridoma (Larchmt), 29, 13-16 (2010).
16. Nedjadi T., Kitteringham N., Campbell F., Jenkins R. E., Park B. K., Navarro P., Ashcroft F., Tepikin A., Neoptolemos J. P., Costello E., Br. J. Cancer, 101, 1145-1154 (2009).
17. Ortiz-Zapater E., Peiró S., Roda O., Corominas J. M., Aguilar S., Ampurdanés C., Real F. X., Navarro P., Am. J. Pathol., 170, 1573-1584 (2007).
18. Díaz V. M., Hurtado M., Thomson T. M., Reventós J., Paciucci R., Gut, 53, 993-1000 (2004).
19. Kesavan K., Ratliff J., Johnson E., Dahlberg W., Asara J. M., Misra P., Frangioni J. V., Jacoby D. B., J. Biol. Chem., 285, 4366-4374 (2010).
20. Chung C. Y., Murphy-Ullrich J. E., Erickson H. P., Mol. Biol. Cell, 7, 883-892 (1996).
21. Arlt A., Gehrz A., Müerköster S., Vorndamm J., Kruse M. L., Fölsch U. R., Schäfer H., Oncogene, 22, 3243-3251 (2003).
22. Brunn G. J., Williams J., Sabers C., Wiederrecht G., Lawrence J. C. Jr., Abraham R. T., EMBO J., 15, 5256-5267 (1996).
23. Gustin J. A., Ozes O. N., Akca H., Pincheira R., Mayo L. D., Li Q., Guzman J. R., Korgaonkar C. K., Donner D. B., J. Biol. Chem., 279, 1615-1620 (2004).