Recombinant expression in human cells of active integrin α1β1-blocking RTS-disintegrin jerdostatin

Toxicon

Volumn 56, Issue 6, 2010, Pages 1052-1058

  Juárez, Paula ^a   Bolás, Gema ^a   de Rezende, Flavia Figueiredo ^b   Calvete, Juan J ^a   Eble, Johannes A ^b  

^a INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^b Center for Molecular Medicine   (Germany)

Author keywords

1 1 integrin inhibitor; Jerdostatin; Mammalian expression system; Recombinant RTS disintegrin

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; DISINTEGRIN; EPITOPE; RECOMBINANT JERDOSTATIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ESCHERICHIA COLI; GENE CONSTRUCT; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN SECRETION; PROTOBOTHTOPS JERDONII; SNAKE; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; BASE SEQUENCE; COLLAGEN TYPE IV; DISINTEGRINS; EPITOPES; GENETIC ENGINEERING; HEK293 CELLS; HUMANS; INTEGRIN ALPHA1BETA1; MOLECULAR SEQUENCE DATA; PEPTIDES; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; RECOMBINANT PROTEINS; TRANSFECTION;

ESCHERICHIA COLI; MAMMALIA; MUS MUSCULUS; PROTOBOTHROPS JERDONII;

EID: 77956063415     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.07.013     Document Type: Article

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