-
1
-
-
58149301316
-
Pharmacological targeting of the serotonergic system for the treatment of obesity
-
Garfield AS, Heisler LK 2009 Pharmacological targeting of the serotonergic system for the treatment of obesity. J Physiol 587:49-60
-
(2009)
J Physiol
, vol.587
, pp. 49-60
-
-
Garfield, A.S.1
Heisler, L.K.2
-
2
-
-
0345258497
-
The developmental role of serotonin: News from mouse molecular genetics
-
Gaspar P, Cases O, Maroteaux L 2003 The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci 4:1002-1012
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 1002-1012
-
-
Gaspar, P.1
Cases, O.2
Maroteaux, L.3
-
4
-
-
37449014336
-
Bone remodeling, energy metabolism, and the molecular clock
-
Rosen CJ 2008 Bone remodeling, energy metabolism, and the molecular clock. Cell Metab 7:7-10
-
(2008)
Cell Metab
, vol.7
, pp. 7-10
-
-
Rosen, C.J.1
-
5
-
-
64349090658
-
Bone, fat, and body composition: Evolving concepts in the pathogenesis of osteoporosis
-
Rosen CJ, Klibanski A 2009 Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis. Am J Med 122:409-414
-
(2009)
Am J Med
, vol.122
, pp. 409-414
-
-
Rosen, C.J.1
Klibanski, A.2
-
6
-
-
61449095573
-
Leptin at 14 y of age: An ongoing story
-
Friedman JM 2009 Leptin at 14 y of age: an ongoing story. Am J Clin Nutr 89:973S-979S
-
(2009)
Am J Clin Nutr
, vol.89
-
-
Friedman, J.M.1
-
7
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G 2000 Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100:197-207
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
Shen, J.7
Vinson, C.8
Rueger, J.M.9
Karsenty, G.10
-
8
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G 2005 Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434:514-520
-
(2005)
Nature
, vol.434
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
Clement, K.11
Vaisse, C.12
Karsenty, G.13
-
9
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G 2002 Leptin regulates bone formation via the sympathetic nervous system. Cell 111:305-317
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
Armstrong, D.7
Ducy, P.8
Karsenty, G.9
-
10
-
-
0025652485
-
Serotonin uptake and serotonin uptake inhibition
-
discussion 79-80
-
Fuller RW, Wong DT 1990 Serotonin uptake and serotonin uptake inhibition. Ann NY Acad Sci 60:68-78; discussion 79-80
-
(1990)
Ann NY Acad Sci
, vol.60
, pp. 68-78
-
-
Fuller, R.W.1
Wong, D.T.2
-
11
-
-
0020082896
-
Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: Their projections in the guinea-pig small intestine
-
DOI 10.1016/0306-4522(82)90271-8
-
Furness JB, Costa M 1982 Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: their projections in the guinea-pig small intestine. Neuroscience 7:341-349 (Pubitemid 12168723)
-
(1982)
Neuroscience
, vol.7
, Issue.2
, pp. 341-349
-
-
Furness, J.B.1
Costa, M.2
-
12
-
-
0037414862
-
Synthesis of serotonin by a second tryptophan hydroxylase isoform
-
Walther DJ, Peter JU, Bashammakh S, Hörtnagl H, Voits M, Fink H, Bader M 2003 Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 299:76
-
(2003)
Science
, vol.299
, pp. 76
-
-
Walther, D.J.1
Peter, J.U.2
Bashammakh, S.3
Hörtnagl, H.4
Voits, M.5
Fink, H.6
Bader, M.7
-
13
-
-
51449114030
-
What do we know about serotonin?
-
Jonnakuty C, Gragnoli C 2008 What do we know about serotonin? J Cell Physiol 217:301-306
-
(2008)
J Cell Physiol
, vol.217
, pp. 301-306
-
-
Jonnakuty, C.1
Gragnoli, C.2
-
14
-
-
3042722258
-
Tryptophan hydroxylase-2 controls brain synthesis
-
DOI 10.1126/science.1097540
-
Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG 2004 Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science 305:217 (Pubitemid 38886729)
-
(2004)
Science
, vol.305
, Issue.5681
, pp. 217
-
-
Zhang, X.1
Beaulieu, J.-M.2
Sotnikova, T.D.3
Gainetdinov, R.R.4
Caron, M.G.5
-
15
-
-
0035800774
-
Expression of serotonin receptors in bone
-
Westbroek I, van der Plas A, de Rooij KE, Klein-Nulend J, Nijweide PJ 2001 Expression of serotonin receptors in bone. J Biol Chem 276:28961-28968
-
(2001)
J Biol Chem
, vol.276
, pp. 28961-28968
-
-
Westbroek, I.1
Van Der Plas, A.2
De Rooij, K.E.3
Klein-Nulend, J.4
Nijweide, P.J.5
-
16
-
-
34249313144
-
Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells
-
Bliziotes M, Eshleman A, Burt-Pichat B, Zhang XW, Hashimoto J, Wiren K, Chenu C 2006 Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells. Bone 39:1313-1321
-
(2006)
Bone
, vol.39
, pp. 1313-1321
-
-
Bliziotes, M.1
Eshleman, A.2
Burt-Pichat, B.3
Zhang, X.W.4
Hashimoto, J.5
Wiren, K.6
Chenu, C.7
-
17
-
-
0034747779
-
Neurotransmitter action in osteoblasts: Expression of a functional system for serotonin receptor activation and reuptake
-
Bliziotes MM, Eshleman AJ, Zhang XW, Wiren KM 2001 Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone 29:477-486
-
(2001)
Bone
, vol.29
, pp. 477-486
-
-
Bliziotes, M.M.1
Eshleman, A.J.2
Zhang, X.W.3
Wiren, K.M.4
-
18
-
-
12344334748
-
Serotonin regulates osteoclast differentiation through its transporter
-
Battaglino R, Fu J, Späte U, Ersoy U, Joe M, Sedaghat L, Stashenko P 2004 Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res 19:1420-1431
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1420-1431
-
-
Battaglino, R.1
Fu, J.2
Späte, U.3
Ersoy, U.4
Joe, M.5
Sedaghat, L.6
Stashenko, P.7
-
19
-
-
69449083603
-
A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
-
Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G 2009 A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 138:976-989
-
(2009)
Cell
, vol.138
, pp. 976-989
-
-
Yadav, V.K.1
Oury, F.2
Suda, N.3
Liu, Z.W.4
Gao, X.B.5
Confavreux, C.6
Klemenhagen, K.C.7
Tanaka, K.F.8
Gingrich, J.A.9
Guo, X.E.10
Tecott, L.H.11
Mann, J.J.12
Hen, R.13
Horvath, T.L.14
Karsenty, G.15
-
20
-
-
12344313055
-
Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth
-
Warden SJ, Robling AG, Sanders MS, Bliziotes MM, Turner CH 2005 Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology 146:685-693
-
(2005)
Endocrinology
, vol.146
, pp. 685-693
-
-
Warden, S.J.1
Robling, A.G.2
Sanders, M.S.3
Bliziotes, M.M.4
Turner, C.H.5
-
21
-
-
56349162283
-
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
-
Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G 2008 Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 135:825-837
-
(2008)
Cell
, vol.135
, pp. 825-837
-
-
Yadav, V.K.1
Ryu, J.H.2
Suda, N.3
Tanaka, K.F.4
Gingrich, J.A.5
Schütz, G.6
Glorieux, F.H.7
Chiang, C.Y.8
Zajac, J.D.9
Insogna, K.L.10
Mann, J.J.11
Hen, R.12
Ducy, P.13
Karsenty, G.14
-
22
-
-
77953407628
-
Relation of serum serotonin levels to bone density and structural parameters in women
-
Modder UI, Achenbach SJ, Amin S, Riggs BL, Melton LJ, Khosla S 2010 Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res 25:414-422
-
(2010)
J Bone Miner Res
, vol.25
, pp. 414-422
-
-
Modder, U.I.1
Achenbach, S.J.2
Amin, S.3
Riggs, B.L.4
Melton, L.J.5
Khosla, S.6
-
23
-
-
50349086333
-
Neuropharmacology of second-generation antipsychotic drugs: A validity of the serotonin-dopamine hypothesis
-
Kuroki T, Nagao N, Nakahara T 2008 Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis. Prog Brain Res 172:199-212
-
(2008)
Prog Brain Res
, vol.172
, pp. 199-212
-
-
Kuroki, T.1
Nagao, N.2
Nakahara, T.3
-
24
-
-
61649124690
-
The 'atypicality' of antipsychotics: A concept re-examined and re-defined
-
Gründer G, Hippius H, Carlsson A 2009 The 'atypicality' of antipsychotics: a concept re-examined and re-defined. Nat Rev Drug Discov 8:197-202
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 197-202
-
-
Gründer, G.1
Hippius, H.2
Carlsson, A.3
-
25
-
-
0029833245
-
Accelerated osteoporosis in psychiatric patients: Possible pathophysiological processes
-
Halbreich U, Palter S 1996 Accelerated osteoporosis in psychiatric patients: possible pathophysiological processes. Schizophr Bull 22:447-454 (Pubitemid 26295347)
-
(1996)
Schizophrenia Bulletin
, vol.22
, Issue.3
, pp. 447-454
-
-
Halbreich, U.1
Palter, S.2
-
26
-
-
33846947984
-
Risk of hip fracture in patients with a history of schizophrenia
-
Howard L, Kirkwood G, Leese M 2007 Risk of hip fracture in patients with a history of schizophrenia. Br J Psychiatry 190:129-134
-
(2007)
Br J Psychiatry
, vol.190
, pp. 129-134
-
-
Howard, L.1
Kirkwood, G.2
Leese, M.3
-
27
-
-
0024466603
-
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
-
Meltzer HY, Matsubara S, Lee JC 1989 Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther 251:238-246
-
(1989)
J Pharmacol Exp Ther
, vol.251
, pp. 238-246
-
-
Meltzer, H.Y.1
Matsubara, S.2
Lee, J.C.3
-
29
-
-
84923666098
-
Risperidone, a second generation antipsychotic alters fat distribution and has a deleterious effect on bone mass in young C57BL6 male mice
-
Dick-de-Paula I, Welch G, Kawai M, Maloney A, Bornstein S, Sikich L, Rosen CJ Risperidone, a second generation antipsychotic alters fat distribution and has a deleterious effect on bone mass in young C57BL6 male mice. Program of the 92nd Annual Meeting of The Endocrine Society, San Diego, CA, 2010
-
Program of the 92nd Annual Meeting of the Endocrine Society, San Diego, CA, 2010
-
-
Dick-de-Paula, I.1
Welch, G.2
Kawai, M.3
Maloney, A.4
Bornstein, S.5
Sikich, L.6
Rosen, C.J.7
-
30
-
-
39249085434
-
Selective serotonin reuptake inhibitors and other antidepressants and risk of fracture
-
Vestergaard P, Rejnmark L, Mosekilde L 2008 Selective serotonin reuptake inhibitors and other antidepressants and risk of fracture. Calcif Tissue Int 82:92-101
-
(2008)
Calcif Tissue Int
, vol.82
, pp. 92-101
-
-
Vestergaard, P.1
Rejnmark, L.2
Mosekilde, L.3
-
31
-
-
34347220867
-
Use of antidepressants and rates of hip bone loss in older women: The study of osteoporotic fractures
-
Diem SJ, Blackwell TL, Stone KL, Yaffe K, Haney EM, Bliziotes MM, Ensrud KE 2007 Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med 167:1240-1245
-
(2007)
Arch Intern Med
, vol.167
, pp. 1240-1245
-
-
Diem, S.J.1
Blackwell, T.L.2
Stone, K.L.3
Yaffe, K.4
Haney, E.M.5
Bliziotes, M.M.6
Ensrud, K.E.7
-
32
-
-
0032474241
-
Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people
-
Liu B, Anderson G, Mittmann N, To T, Axcell T, Shear N 1998 Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people. Lancet 351:1303-1307
-
(1998)
Lancet
, vol.351
, pp. 1303-1307
-
-
Liu, B.1
Anderson, G.2
Mittmann, N.3
To, T.4
Axcell, T.5
Shear, N.6
-
33
-
-
33846492331
-
Predictors of non-spine fracture in elderly men: The MrOS study
-
Lewis CE, Ewing SK, Taylor BC, Shikany JM, Fink HA, Ensrud KE, Barrett-Connor E, Cummings SR, Orwoll E 2007 Predictors of non-spine fracture in elderly men: the MrOS study. J Bone Miner Res 22:211-219
-
(2007)
J Bone Miner Res
, vol.22
, pp. 211-219
-
-
Lewis, C.E.1
Ewing, S.K.2
Taylor, B.C.3
Shikany, J.M.4
Fink, H.A.5
Ensrud, K.E.6
Barrett-Connor, E.7
Cummings, S.R.8
Orwoll, E.9
-
34
-
-
54449099520
-
Fracture risk from psychotropic medications: A population-based analysis
-
Bolton JM, Metge C, Lix L, Prior H, Sareen J, Leslie WD 2008 Fracture risk from psychotropic medications: a population-based analysis. J Clin Psychopharmacol 28:384-391
-
(2008)
J Clin Psychopharmacol
, vol.28
, pp. 384-391
-
-
Bolton, J.M.1
Metge, C.2
Lix, L.3
Prior, H.4
Sareen, J.5
Leslie, W.D.6
-
35
-
-
33846440508
-
Effect of selective serotonin reuptake inhibitors on the risk of fracture
-
DOI 10.1001/archinte.167.2.188
-
Richards JB, Papaioannou A, Adachi JD, Joseph L, Whitson HE, Prior JC, Goltzman D 2007 Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med 167:188-194 (Pubitemid 46148067)
-
(2007)
Archives of Internal Medicine
, vol.167
, Issue.2
, pp. 188-194
-
-
Richards, J.B.1
Papaioannou, A.2
Adachi, J.D.3
Joseph, L.4
Whitson, H.E.5
Prior, J.C.6
Goltzman, D.7
-
36
-
-
77950302945
-
A cross sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys
-
Calarge CA, Zimmerman B, Xie D, Kuperman S, Schlechte JA 2010 A cross sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys. J Clin Psychiatry 71:338-347
-
(2010)
J Clin Psychiatry
, vol.71
, pp. 338-347
-
-
Calarge, C.A.1
Zimmerman, B.2
Xie, D.3
Kuperman, S.4
Schlechte, J.A.5
-
37
-
-
54449089554
-
Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures
-
Ziere G, Dieleman JP, van der Cammen TJ, Hofman A, Pols HA, Stricker BH 2008 Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures. J Clin Psychopharmacol 28:411-417
-
(2008)
J Clin Psychopharmacol
, vol.28
, pp. 411-417
-
-
Ziere, G.1
Dieleman, J.P.2
Van Der Cammen, T.J.3
Hofman, A.4
Pols, H.A.5
Stricker, B.H.6
-
38
-
-
77950532014
-
Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels
-
Warden SJ, Hassett SM, Bond JL, Rydberg J, Grogg JD, Hilles EL, Bogenschutz ED, Smith HD, Fuchs RK, Bliziotes MM, Turner CH 2010 Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels. Bone 46: 985-992
-
(2010)
Bone
, vol.46
, pp. 985-992
-
-
Warden, S.J.1
Hassett, S.M.2
Bond, J.L.3
Rydberg, J.4
Grogg, J.D.5
Hilles, E.L.6
Bogenschutz, E.D.7
Smith, H.D.8
Fuchs, R.K.9
Bliziotes, M.M.10
Turner, C.H.11
-
39
-
-
34047126787
-
Fluoxetine treatment increases trabecular bone formation in mice
-
Battaglino R, Vokes M, Schulze-Späte U, Sharma A, Graves D, Kohler T, Müller R, Yoganathan S, Stashenko P 2007 Fluoxetine treatment increases trabecular bone formation in mice. J Cell Biochem 100:1387-1394
-
(2007)
J Cell Biochem
, vol.100
, pp. 1387-1394
-
-
Battaglino, R.1
Vokes, M.2
Schulze-Späte, U.3
Sharma, A.4
Graves, D.5
Kohler, T.6
Müller, R.7
Yoganathan, S.8
Stashenko, P.9
-
40
-
-
1642559543
-
The influence of selective serotonin reuptake inhibitors on human platelet serotonin
-
Maurer-Spurej E, Pittendreigh C, Solomons K 2004 The influence of selective serotonin reuptake inhibitors on human platelet serotonin. Thromb Haemost 91:119-128
-
(2004)
Thromb Haemost
, vol.91
, pp. 119-128
-
-
Maurer-Spurej, E.1
Pittendreigh, C.2
Solomons, K.3
-
41
-
-
75449100367
-
New perspectives on the neurodevelopmental effects of SSRIs
-
Homberg JR, Schubert D, Gaspar P 2010 New perspectives on the neurodevelopmental effects of SSRIs. Trends Pharmacol Sci 31:60-65
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 60-65
-
-
Homberg, J.R.1
Schubert, D.2
Gaspar, P.3
-
42
-
-
53649102098
-
Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs)
-
Narboux-Nême N, Pavone LM, Avallone L, Zhuang X, Gaspar P 2008 Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology 55:994-1005
-
(2008)
Neuropharmacology
, vol.55
, pp. 994-1005
-
-
Narboux-Nême, N.1
Pavone, L.M.2
Avallone, L.3
Zhuang, X.4
Gaspar, P.5
-
44
-
-
30644473109
-
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
-
Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua Jr S, Elmquist JK, Lowell BB 2006 Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49: 191-203
-
(2006)
Neuron
, vol.49
, pp. 191-203
-
-
Dhillon, H.1
Zigman, J.M.2
Ye, C.3
Lee, C.E.4
McGovern, R.A.5
Tang, V.6
Kenny, C.D.7
Christiansen, L.M.8
White, R.D.9
Edelstein, E.A.10
Coppari, R.11
Balthasar, N.12
Cowley, M.A.13
Chua Jr., S.14
Elmquist, J.K.15
Lowell, B.B.16
-
45
-
-
0026685011
-
Improved diagnosis of carcinoid tumors by measurement of platelet serotonin
-
Kema IP, de Vries EG, Schellings AM, Postmus PE, Muskiet FA 1992 Improved diagnosis of carcinoid tumors by measurement of platelet serotonin. Clin Chem 38:534-540
-
(1992)
Clin Chem
, vol.38
, pp. 534-540
-
-
Kema, I.P.1
De Vries, E.G.2
Schellings, A.M.3
Postmus, P.E.4
Muskiet, F.A.5
-
46
-
-
0037313169
-
Bone metastases in carcinoid tumors: Clinical features, imaging characteristics, and markers of bone metabolism
-
Meijer WG, van der Veer E, Jager PL, van der Jagt EJ, Piers BA, Kema IP, de Vries EG, Willemse PH 2003 Bone metastases in carcinoid tumors: clinical features, imaging characteristics, and markers of bone metabolism. J Nucl Med 44:184-191
-
(2003)
J Nucl Med
, vol.44
, pp. 184-191
-
-
Meijer, W.G.1
Van Der Veer, E.2
Jager, P.L.3
Van Der Jagt, E.J.4
Piers, B.A.5
Kema, I.P.6
De Vries, E.G.7
Willemse, P.H.8
|