Greater exercise sweating in obese women with polycystic ovary syndrome compared with obese controls

Medicine and Science in Sports and Exercise

Volumn 42, Issue 9, 2010, Pages 1660-1668

  Stachenfeld, Nina S ^a,b   Yeckel, Catherine Weikart ^a,b   Taylor, Hugh S ^b  

^a JOHN B PIERCE LABORATORY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ESTROGEN; GnRH ANTAGONIST; POLYCYSTIC OVARY SYNDROME; TEMPERATURE REGULATION; TESTOSTERONE

Indexed keywords

ENDOTHELIN 1; ESTRADIOL; GONADORELIN; PROGESTERONE; TESTOSTERONE;

ADULT; ARTICLE; BLOOD; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; EXERCISE; FEMALE; HUMAN; INSULIN RESISTANCE; OBESITY; OVARY POLYCYSTIC DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY; SWEATING; THERMOREGULATION;

ADULT; BODY TEMPERATURE REGULATION; ENDOTHELIN-1; ESTRADIOL; EXERCISE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; INSULIN RESISTANCE; OBESITY; POLYCYSTIC OVARY SYNDROME; PROGESTERONE; SWEATING; TESTOSTERONE; YOUNG ADULT;

EID: 77956041870     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e3181d8cf68     Document Type: Article

References (37)

1. Adams WC, Mack GW, Langhans GW, Nadel ER. Effects of varied air velocity on sweating and evaporative rates during exercise. J Appl Physiol. 1992;73:2668-2674
2. Armstrong L, Casa D, Millard-Stafford M, Moran D, Pyne S, Roberts W. American College of Sports Medicine position stand. Exertional heat illness during training and competition. Med Sci Sports Exerc. 2007;39(3):556-572
3. Avellini BA, Shapiro Y, Pandolf KB, Pimental NA, Goldman RF. Physiological responses of men and women to prolonged dry heat exposure. Aviat Space Environ Med. 1980;51:1081-1085
4. Balen AH, Dresner M, Scott EM, Drife JO. Should obese women with polycystic ovary syndrome receive treatment for infertility? BMJ. 2006;332:434-435
5. Barontini M, Garcia-Rudaz MC, Veldhuis JD. Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome. Arch Med Res. 2001;32:544-552
6. Cascella T, Palomba S, Tauchmanova L, et al. Serum aldosterone concentration and cardiovascular risk in women with polycystic ovarian syndrome. J Clin Endocrinol Metab. 2006;91:4395-4400
7. Charkoudian N, Johnson JM. Modification of active cutaneous vasodilation by oral contraceptive hormones. J Appl Physiol. 1997;83:2012-2018
8. Charkoudian N, Johnson JM. Reflex control of cutaneous vasoconstrictor system is reset by exogenous female reproductive hormones. J Appl Physiol. 1999;87:381-385
9. Cheuvront SN, Bearden SE, Kenefick RW, et al. A simple and valid method to determine thermoregulatory sweating threshold and sensitivity. J Appl Physiol. 2009;107:69-75.
10. Colton T. Statistics in Medicine. Boston (MA): Little Brown & Co; 19 p. 142-146
11. Donnelly JE, Blair SN, Jakicic JM, Manore MM, Rankin JW, Smith BK. American College of Sports Medicine position stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459-471
12. Graichen H, Rascati R, Gonzalez RR. Automated dew-point temperature sensor. J Appl Physiol. 1982;52:1658-1660
13. Hardy JD. Heat transfer. In: Newburgh LH, editor. Physiology of Heat Regulation and Science of Clothing. Philadelphia (PA): Saunders; 19 p. 78-108.
14. Hart LE, Sutton JR. Environmental considerations for exercise. Cardiol Clin. 1987;5:245-258
15. Hirata K, Nagasaka T, Hirashita M, Takahata T, Nuriomura T. Effects of human menstrual cycle on thermoregulatory vasodilation during exercise. Eur J Appl Physiol. 1986;54:559-565
16. Jakicic JM, Clark K, Colmena E, et al. Appropriate intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2001;33(12):2145-2156
17. Kolka MA, Stephenson LA. Effect of luteal phase elevation in core temperature on forearm blood flow during exercise. J Appl Physiol. 1997;82:1079-1083
18. Moran LJ, Brinkworth G, Noakes M, Norman RJ. Effects of lifestyle modification in polycystic ovarian syndrome. Reprod Biomed Online. 2006;12:569-578
19. Nadel ER, Bullard RW, Stolwijk JA. Importance of skin temperature in the regulation of sweating. J Appl Physiol. 1971;31:80-87
20. Nadel ER, Mitchell JW, Stolwijk JAJ. Differential thermal sensitivity in the human skin. Pflugers Arch. 1973;340:71-76
21. Nakayama T, Suzuki M, Ishizuka N. Action of progesterone on thermosensitive neurons. Nature. 1975;258:80.
22. Norman RJ, Davies MJ, Lord J, Moran LJ. The role of lifestyle modification in polycystic ovary syndrome. Trends Endocrinol Metab. 2002;13:251-257
23. Oberye JJL, Mannaerts BMJL, Huisman JAM, Timmer CJ. Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part I. Absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers. Fertil Steril. 1999;72:1001-1005
24. Oberye JJL, Mannaerts BMJL, Huisman JAM, Timmer CJ. Pharmacokinetic and Pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part II. Dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers. Fertil Steril. 1999;72:1006-1012
25. Rossi GP, Belfiore A, Bernini G, et al. Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients. J Clin Endocrinol Metab. 2008;93:2566-2571
26. Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc. 2007;39(2):377-390
27. Shapiro Y, Moran D, Epstein Y. Acclimatization strategies- preparing for exercise in the heat. Int J Sports Med. 1998; 19(2 suppl):S161-3.
28. Shapiro Y, Pandolf KB, Avellini BA, Pimental NA, Goldman RF. Physiological responses of men and women to humid and dry heat. J Appl Physiol. 1980;49:1-8.
29. Shibasaki M, Davis SL, Cui J, et al. Neurally mediated vasoconstriction is capable of decreasing skin blood flow during orthostasis in the heat-stressed human. J Physiol. 2006;575:953-959
30. Silva NL, Boulant JA. Effects of testosterone, estradiol, and temperature on neurons in preoptic tissue slices. Am J Physiol. 1986; 250:R625-32.
31. Stachenfeld NS, Silva C, Keefe DL. Estrogen modifies the temperature effects of progesterone. J Appl Physiol. 2000;88: 1643-1649
32. Stephenson LA, Kolka MA. Thermoregulation in women. In: Holloszy JO, editor. Exercise and Sports Science Reviews. Philadelphia (PA): Williams & Wilkins; 19 p. 231-262
33. Stephenson LA, Kolka MA. Esophageal temperature threshold for sweating decreases before ovulation in premenopausal women. J Appl Physiol. 1999;86:22-28
34. Tang T, Glanville J, Hayden CJ, White D, Barth JH, Balen AH. Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study. Hum Reprod. 2006;21:80-89
35. Trivax B, Azziz R. Diagnosis of polycystic ovary syndrome. Clin Obstet Gynecol. 2007;50:168-177
36. Tsilchorozidou T, Overton C, Conway GS. The pathophysiology of polycystic ovary syndrome. Clin Endocrinol. 2004;60: 1-17.
37. Tuomela T, Miettinen P, Viinikka L, Perheentupa J. Estrogen- androgen antagonism in the regulation of epidermal growth factor in mouse submandibular salivary gland and kidneys. Life Sci. 1990;47:1925-1932