1,5-Dicaffeoylquinic acid-mediated glutathione synthesis through activation of Nrf2 protects against OGD/reperfusion-induced oxidative stress in astrocytes

Brain Research

Volumn 1347, Issue , 2010, Pages 142-148

  Cao, Xu ^a,b   Xiao, Haibing ^b   Zhang, Ying ^a   Zou, Liangyu ^a   Chu, Yinghao ^c   Chu, Xiaofan ^a  

^a JINAN UNIVERSITY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

1,5 Dicaffeoylquinic acid; Glutathione; Ischemia reperfusion; Nrf2; Oxidative stress

Indexed keywords

CYNARINE; GLUCOSE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; OXYGEN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; CAFFEOYLQUINIC ACID; QUINIC ACID; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; ANOXIA; BRAIN CORTEX; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; NEWBORN; PATHOLOGY; PROCEDURES;

RATTUS;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANOXIA; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; QUINIC ACID; RATS; REACTIVE OXYGEN SPECIES; REPERFUSION; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 77955985454     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.05.072     Document Type: Article

References (38)

1. Anderson, M. F., Sims, N. R., 2002. The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions. J. Neurochem. 81, 541-549.
2. Bains, J. S., Shaw, C. A., 1997. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res. Rev. 25, 335-358.
3. Bondarenko, A., Chesler, M., 2001. Rapid astrocyte death induced by transient hypoxia, acidosis, and extracellular ion shifts. Glia 34, 134-142.
4. Chan, P. H., 1996. Role of oxidants in ischemic brain damage. Stroke 27, 1124-1129.
5. Chen, Z. H., Yoshida, Y., Saito, Y., Sekine, A., Noguchi, N., Niki, E., 2006. Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta (12, 14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. J. Biol. Chem. 281, 14440-14445.
6. Ciccarelli, R., D'Alimonte, I., Santavenere, C., D'Auro, M., Ballerini, P., Nargi, E., Buccella, S., NicosiaFolco, S., Caciagli, F., Iorio, P. Di., 2004. Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. Eur. J. Neurosci. 20, 1514-1524.
7. Dawson, D. A., Graham, D. I., McCulloch, J., Macrae, I. M., 1994. Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia. Br. J. Pharmacol. 113, 247-253.
8. Dienel, G. A., Hertz, L., 2005. Astrocytic contributions to bioenergetics of cerebral ischemia. Glia 50, 362-388.
9. Dringen, R., 2000. Metabolism and functions of glutathione in brain. Prog. Neurobiol. 62, 649-671.
10. Fernández-Checa, J. C., García-Ruiz, C., Ookhtens, M., Kaplowitz, N., 1991. Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress. J. Clin. Invest. 87, 397-405.
11. Fisk, L., Nalivaeva, N. N., Boyle, J. P., Peers, C. S., Turner, A. J., 2007. Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes. Neurochem. Res. 32, 1741-1748.
12. Goldberg, M. P., Weiss, J. H., Pham, P. C., Choi, D. W., 1987. N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture. J. Pharmacol. Exp. Ther. 243, 784-791.
13. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 280, 3548-3554.
14. Hung, T. M., Na, M., Thuong, P. T., Su, N. D., Sok, D., Song, K. S., Seong, Y. H., Bae, K., 2006. Antioxidant activity of caffeoyl quinic acid derivatives from the roots of Dipsacus asper Wall. J. Ethnopharmacol. 108, 188-192.
15. Jaiswal, A. K., 2000. Regulation of genes encoding NAD (P) H:quinone oxidoreductases. Free Radic. Biol. Med. 29, 254-262.
16. Juurlink, B. H., 1997. Response of glial cells to ischemia: roles of reactive oxygen species and glutathione. Neurosci. Biobehav. Rev. 21, 151-166.
17. Kim, S. K., Yang, J. W., Kim, M. R., Roh, S. H., Kim, H. G., Lee, K. Y., Jeong, H. G., Kang, K. W., 2008. Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells. Free Radic Biol Med. 45, 537-546.
18. Kode, A., Rajendrasozhan, S., Caito, S., Yang, S. R., Megson, I. L., Rahman, I., 2008. Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 294, 478-488.
19. Lee, W. T., Hong, S., Yoon, S. H., Kim, J. H., Park, K. A., Seong, G. J., Lee, J. E., 2009. Neuroprotective effects of agmatine on oxygen-glucose deprived primary-cultured astrocytes and nuclear translocation of nuclear factor-kappa B. Brain Res. 1281, 64-70.
20. Lerouet, D., Beray-Berthat, V., Palmier, B., Plotkine, M., Margaill, I., 2002. Changes in oxidative stress, iNOS activity and neutrophil infiltration in severe transient focal cerebral ischemia in rats. Brain Res. 958, 166-175.
21. Li, R., Bianchet, M. A., Talalay, P., Amzel, L. M., 1995. The three-dimensional structure of NAD (P) H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. Proc. Natl. Acad. Sci. USA 92, 8846-8850.
22. Liu, D., Smith, C. L., Barone, F. C., Ellison, J. A., Lysko, P. G., Li, K., Simpson, I. A., 1999. Astrocytic demise precedes delayed neuronal death in focal ischemic rat brain. Mol. Brain Res. 68, 29-41.
23. Liu, Y., Kern, J. T., Walker, J. R., Johnson, J. A., Schultz, P. G., Luesch, H., 2007. A genomic screen for activators of the antioxidant response element. Proc. Natl. Acad. Sci. USA 104, 5205-5210.
24. Moi, P., Chan, K., Asunis, I., Cao, A., Kan, Y. W., 1994. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc. Natl. Acad. Sci. USA 91, 9926-9930.
25. Mulcahy, R. T., Gipp, J. J., 1995. Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene. Biochem. Biophys. Res. Commun. 209, 227-233.
26. Nakajima, Y., Shimazawa, M., Mishima, S., Hara, H., 2007. Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions. Life Sci. 80, 370-377.
27. Nguyen, T., Sherratt, P. J., Pickett, C. B., 2003. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu. Rev. Pharmacol. Toxicol. 43, 233-260.
28. Ouyang, Y. B., Giffard, R. G., 2004. Changes in astrocyte mitochondrial function with stress: effects of Bcl-2 family proteins. Neurochem. Int. 45, 371-379.
29. Park, J. B., 2009. 5-Caffeoylquinic acid and caffeic acid orally administered suppress P-selectin expression on mouse platelets. J. Nutr. Biochem. 20, 800-805.
30. Pfeiffer-Guglielmi, B., Fleckenstein, B., Jung, G., Hamprecht, B., 2003. Immunocytochemical localization of glycogen phosphorylase isozymes in rat nervous tissues by using isozyme-specific antibodies. J. Neurochem. 85, 73-81.
31. Piantadosi, C. A., Zhang, J., 1996. Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 27, 327-331.
32. Prestera, T., Talalay, P., Alam, J., Ahn, Y. I., Lee, P. J., Choi, A. M., 1995. Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Mol Med. 1, 827-837.
33. Schulz, J. B., Lindenau, J., Seyfried, J., Dichgans, J., 2000. Glutathione, oxidative stress and neurodegeneration. Eur. J. Biochem. 267, 4904-4911.
34. Suzuki, Y., Takahashi, H., Fukuda, M., Hino, H., Kobayashi, K., Tanaka, J., Ishii, E., 2009. beta-Hydroxybutyrate alters GABA-transaminase activity in cultured astrocytes. Brain Res. 1268, 17-23.
35. Toroser, D., Sohal, R. S., 2005. Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L. Biochem. Biophys. Res. Commun. 326, 586-593.
36. Usami, H., Kusano, Y., Kumagai, T., Osada, S., Itoh, K., Kobayashi, A., Yamamoto, M., Uchida, K., 2005. Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors. J. Biol. Chem. 280, 25267-25276.
37. Yang, C., Zhang, X., Fan, H., Liu, Y., 2009. Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res. 1282, 133-141.
38. Yu, A. C., Wong, H. K., Yung, H. W., Lau, L. T., 2001. Ischemia-induced apoptosis in primary cultures of astrocytes. Glia 35, 121-130.