Magnetic resonance imaging and relaxometry to study water transport mechanisms in a commercially available gastrointestinal therapeutic system (GITS) tablet

International Journal of Pharmaceutics

Volumn 397, Issue 1-2, 2010, Pages 27-35

  Broadbent, Amber L ^a   Fell, Rob J ^a   Codd, Sarah L ^a   Lightley, Kim A ^b   Konagurthu, Sanjay ^b   Koehler King, Dory G ^b   Seymour, Joseph D ^a  

^a Idaho National Laboratory   (United States)

^b Bend Research Incorporated   (United States)

Author keywords

Controlled release; Diffusion; Drug delivery; Magnetic resonance imaging; Osmotic pressure; Relaxometry

Indexed keywords

DOXAZOSIN; POLYMER;

ANALYTIC METHOD; ARTICLE; DIFFUSION; DIGITAL IMAGING; DRUG RELEASE; DRUG SOLUBILITY; GASTROINTESTINAL THERAPEUTIC SYSTEM TABLET; HYDRATION; MAGNETIC RESONANCE RELAXOMETRY; NUCLEAR MAGNETIC RESONANCE IMAGING; OSMOSIS; OSMOTIC PRESSURE; PRIORITY JOURNAL; TABLET FORMULATION; WATER TRANSPORT;

DELAYED-ACTION PREPARATIONS; DOXAZOSIN; EXCIPIENTS; GASTROINTESTINAL TRACT; MAGNETIC RESONANCE IMAGING; SOLUBILITY; TABLETS; WATER;

EID: 77955982261     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.06.047     Document Type: Article

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