Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: An immunohistochemical study from a high incidence area in northern China

Diseases of the Esophagus

Volumn 23, Issue 6, 2010, Pages 487-492

  Jiang, H ^a   Gong, M ^a   Cui, Y ^a   Ma, K ^a   Chang, D ^a   Wang, T Y ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Caspase 3; Esophageal squamous cell carcinoma; Immunohistochemistry; Prognosis

Indexed keywords

CASPASE 3;

ADULT; ARTICLE; CANCER CELL; CANCER INCIDENCE; CANCER SURGERY; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL INFILTRATION; CHINA; CONTROLLED STUDY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS MUCOSA; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; UPREGULATION;

CARCINOMA, SQUAMOUS CELL; CASPASE 3; CHINA; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUCOUS MEMBRANE; PRECANCEROUS CONDITIONS; PROGNOSIS; UP-REGULATION;

EID: 77955977688     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2009.01043.x     Document Type: Article

References (32)

1. Lu S H. Alterations of oncogene and tumor suppressor genes in esophageal cancer in China. Mutat Res 2000, 462:343-53.
2. Chang D, Wang T Y, Li H C, Wei J C, Song J X. Prognostic significance of PTEN expression in esophageal squamous cell carcinoma from Linzhou City, a high incidence area of northern China. Dis Esophagus 2007, 20:491-6.
3. Wang L D, Zhou Q, Yang W C, Yang C S. Apoptosis and cell proliferation in esophageal precancerous and cancerous lesions: study of a high-risk population in northern China. Anticancer Res 1999, 19:369-74.
4. Gown A M, Willingham M C. Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3. J Histochem Cytochem 2002, 50:449-54.
5. Resendes A R, Majo N, Segales J. Apoptosis in normal lymphoid organs from healthy normal, conventional pigs at different ages detected by TUNEL and cleaved caspase-3 immunohistochemistry in paraffin-embedded tissues. Vet Immunol Immunopathol 2004, 99:203-13.
6. Jakob S, Corazza N, Diamantis E, Kappeler A, Brunner T. Detection of apoptosis in vivo using antibodies against caspase-induced neo-epitopes. Methods 2008, 44:255-61.
7. Parenti A, Leo G, Porzionato A, Zaninotto G, Rosato A, Ninfo V. Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis. Hum Pathol 2006, 37:16-22.
8. Persad R, Liu C, Wu T T. Overexpression of caspase-3 in hepatocellular carcinomas. Mod Pathol 2004, 17:861-7.
9. Winter R N, Kramer A, Borkowski A, Kyprianou N. Loss of Caspase-1 and Caspase-3 protein expression in human prostate cancer. Cancer Res 2001, 61:1227-32.
10. Vakkala M, Paakko P, Soini Y. Expression of Caspase-3,6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion. Br J Cancer 1999, 81:592-9.
11. Devarajan E, Sahin A A, Chen J S. Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance. Oncogene 2002, 21:8843-51.
12. Saad A, Yeap B, Thunnissen F. Immunohistochemical markers associated with brain metastases in patients with non-small cell lung carcinoma. Cancer 2008, 113:2129-38.
13. Hsia J Y, Chen C Y, Chen J T. Prognostic significance of caspase-3 expression in primary resected esophageal squamous cell carcinoma. Eur J Surg Oncol 2003, 29:44-8.
14. Kurabayashi A, Furihata M, Matsumoto M, Ohtsuki Y, Sasaguri S, Ogoshi S. Expression of Bax and apoptosis-related proteins in human esophageal squamous cell carcinoma including dysplasia. Mod Pathol 2001, 14:741-7.
15. Cao F M, Zhang X H, Yan X. Expression and prognostic significance of survivin and caspase-3 in esophageal squamous-cell carcinoma and their relationship with HSPs expression. Zhonghua Zhong Liu Za Zhi 2005, 27:416-19.
16. Chang M S, Lee H S, Lee B L, Kim Y T, Lee J S, Kim W H. Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers. Pathol Res Pract 2005, 201:417-25.
17. Ray S K, Patel S J, Welsh C T, Wilford G G, Hogan E L, Banik N L. Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3. J Neurosci Res 2002, 69:197-200.
18. Oca J, Azuara D, Sanchez-Santos R. Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer. Int J Colorectal Dis 2008, 23:21-7.
19. Peiró G, Diebold J, Baretton G B. Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome. Int J Gynecol Pathol 2001, 20:359-67.
20. Lu S, Zhang B, Wang Z. Expression of survivin, cyclinD1, p21(WAF1), caspase-3 in cervical cancer and its relation with prognosis. J Huazhong Univ Sci Technolog Med Sci 2005, 25:78-81.
21. Yoo N J, Kim H S, Kim S Y. Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study. APMIS 2002, 110:825-32.
22. Sun Y, Chen X, Liu J. Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication. Cancer Detect Prev 2006, 30:168-73.
23. Li Y, Wang C, Meng K, Chen L B, Zhou X J. Influence of survivin and caspase-3 on cell apoptosis and prognosis in gastric carcinoma. World J Gastroenterol 2004, 10:1984-8.
24. Oudejans J, Harijadi A, Cillessen S. Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome. Mod Pathol 2005, 18:877-88.
25. Isobe N, Onodera H, Mori A. Caspase-3 expression in human gastric carcinoma and its clinical significance. Oncology 2004, 66:201-9.
26. Lukes P, Pácová H, Kucera T, Veselý D, Martínek J, Astl J. Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils. Folia Biol (Praha) 2008, 54:141-45.
27. Oudejans J, Harijadi A, Cillessen S. Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome. Mod Pathol 2005, 18:877-88.
28. Nomura Y, Yoshida S, Karube K. Estimation of the relationship between caspase-3 expression and clinical outcome of Burkitt's and Burkitt-like lymphoma. Cancer Sci 2008, 99:1564-9.
29. Oca J, Azuara D, Sanchez-Santos R. Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer. Int J Colorectal Dis 2008, 23:21-7.
30. Kobayashi T, Masumoto J, Tada T, Hongo K, Nakayama J. Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas. Clin Cancer Res 2007, 13:3868-74.
31. Volm M, Koomagi R. Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer. Oncol Rep 2000, 7:95-8.
32. Jeong I, Kim S, Jeon H. Prognostic value of apoptosis-related markers in urothelial cancer of the upper urinary tract. Hum Pathol 2009, 40:668-77.