Star fruit: Simultaneous neurotoxic and nephrotoxic effects in people with previously normal renal function

NDT Plus

Volumn 2, Issue 6, 2009, Pages 485-488

  Neto, Moyses Miguel ^a   Silva, Gyl E B ^a   Costa, Roberto S ^a   Neto, Osvaldo M Vieira ^a   Garcia Cairasco, Norberto ^a   Lopes, Norberto P ^a   Haendchen, Priscila F C ^a   Silveira, Cintya ^a   Mendes, Alcino R ^a   Filho, Ramon R ^a   Dantas, Marcio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

acute oxalate nephropathy; nephrotoxicity; neurotoxicity; star fruit

Indexed keywords

CALCIUM OXALATE; CREATININE;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; FEMALE; FOOD INTAKE; FRUIT; FRUIT JUICE; HICCUP; HISTIOCYTE; HUMAN; INFLAMMATORY INFILTRATE; INSOMNIA; KIDNEY BIOPSY; KIDNEY FUNCTION; LOW BACK PAIN; LYMPHOCYTE; MALE; MICROSCOPY; NEPHROTOXICITY; NEUROTOXICITY; NEUTROPHIL; PRIORITY JOURNAL; STAR FRUIT; VOMITING;

EID: 77955928919     PISSN: 17530784     EISSN: 17530792     Source Type: Journal    
DOI: 10.1093/ndtplus/sfp108     Document Type: Article

References (16)

1. Neto MM, Robl F, Netto JC. Intoxication by star fruit (Averrhoa carambola) in six dialysis patients (Preliminary report). Nephrol Dial Transplant 1998; 13: 570-572
2. Chang JM, Hwang SJ, Kuo HT et al. Fatal outcome after ingestion of star fruit (Averrhoa carambola) in uremic patients. Am J Kidney Dis 2000; 35: 189-193
3. Neto MM, Da Costa JA, Garcia-Cairasco N et al. Intoxication by star fruit (Averrhoa carambola) in 32 uraemic patients: treatment and outcome. Nephrol Dial Transplant 2003; 18: 120-125
4. Chen CL, Fang HC, Chou KJ et al. Acute oxalate nephropathy after ingestion of star fruit. Am J Kidney Dis 2001; 37: 418-422
5. Moyses-Neto M, Carolino RO, Lopes NP et al. Star-fruit. In: De Broe M, Porter GA (ed). Clinical Nephrotoxins, vol.1. New York, NY: Springer, 2008, pp. 901-912
6. Tsai JP, Fang TC, Wang CH et al. Fatal outcome after ingestion of star fruit ina a severe chronic kidney disease patient. Dial Transplant 2009; 38: 102-105
7. Massey LK. Food oxalate: factors affecting measurement, biological variation, and bioavailability. J Am Diet Assoc 2007; 107: 1191-1194
8. Sanz P, Reig R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol 1992; 13: 342-345
9. Fang HC, Chen CL,Wang JS et al.Acute oxalate nephropathy induced by star fruit in rats. Am J Kidney Dis 2001; 38: 876-880
10. Fang HC, Lee PT, Lu PJ et al.Mechanisms of star fruit-induced acute renal failure. Food Chem Toxicol 2008; 46: 1744-1752
11. Chen CL, Chou KJ, Wang JS et al. Neurotoxic effects of carambola in rats: the role of oxalate. J Formos Med Assoc 2002; 101: 337-341
12. Fang HC, Chen CL, Lee PT et al. The role of oxalate in star fruit neurotoxicity of five-sixths nephrectomized rats. Food Chem Toxicol 2007; 45: 1764-1769
13. Niticharoenpong K, Chalermsanyakorn P, Panvichian R et al. Acute deterioration of renal function induced by star fruit ingestion in a patient with chronic kidney disease. J Nephrol 2006; 19: 682-686
14. Carolino RO, Beleboni RO, Pizzo AB et al. Convulsant activity and neurochemical alterations induced by a fraction obtained from fruit Averrhoa carambola (Oxalidaceae: Geraniales). Neurochem Int 2005; 46: 523-531
15. Garcia-Cairasco N, Castro OW, Leite-Santos F et al. A comparative study of status epilepticus, spountaneus recurrent seizures and neurodegeneration induced by intrahippocampal microinjections of pilocarpine and caramboxin, a star fruit neurotoxin, in Wistar adult male rats. Epilepsia 2007; 48(S6): 282-283
16. Beier RC. Natural pesticides and bioactive components in foods. Rev Environ Contam Toxicol 1990; 113: 47-137