Convulsant activity and neurochemical alterations induced by a fraction obtained from fruit Averrhoa carambola (Oxalidaceae: Geraniales)

Neurochemistry International

Volumn 46, Issue 7, 2005, Pages 523-531

  Carolino, Ruither O G ^a   Beleboni, Renê O ^a   Pizzo, Andrea B ^a   Del Vecchio, Flavio ^a   Garcia Cairasco, Norberto ^a   Moyses Neto, Miguel ^a   Dos Santos, Wagner F ^a   Coutinho Netto, Joaquim ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Averrhoa carambola; Convulsant; GABA glutamate uptake, release and binding; Video electroencephalogram

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; NEUROTOXIN; OXALIC ACID;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVERRHOA CARAMBOLA; BINDING AFFINITY; BRAIN CORTEX; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CONVULSION; ELECTROENCEPHALOGRAM; ELECTROENCEPHALOGRAPHY; EPILEPTIC DISCHARGE; EPILEPTIC STATE; FRUIT; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; IC 50; INHIBITION KINETICS; MALE; MOLECULAR WEIGHT; MOLECULE; MOUSE; NERVOUS SYSTEM; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECORDING; TONIC CLONIC SEIZURE; VIDEORECORDING;

ANIMALIA; AVERRHOA CARAMBOLA; GERANIALES; OXALIDACEAE;

EID: 16344375253     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2005.02.002     Document Type: Article

References (37)

1. A.F. Bicalho, C. Guatimosim, M.A. Prado, M.V. Gomez, and M.A. Romano-Silva Investigation of the modulation of glutamate release by sodium channels using neurotoxins Neuroscience 113 2002 115 123
2. H.F. Bradford Glutamate, GABA and epilepsy Prog. Neurobiol. 47 1995 477 511
3. R.O.G. Carolino, R.O. Beleboni, M. Moyses-Neto, N. Garcia-Cairasco, and J. Coutinho Netto Biological activity and purification of a neurotoxin from Averrhoa carambola star fruit (Oxalidaceae) Proceedings of the Seventh Symposium of the Brazilian Society on Toxinology (SBTx) Pirenópolis, Brazil, 2002 J. Venom. Anim. Toxins Incl. Trop. Dis. 9 2003 542
4. P. Cayot, and G. Tainturier The quantification of protein amino groups by the trinitrobenzenesulfonic acid method: a reexamination Anal. Biochem. 249 1997 184 200
5. 31Phosphorous and single voxel proton MR spectroscopy and diffusion-weighted imaging in a case of star fruit poisoning AJNR Am. J. Neuroradiol. 23 2002 1557 1560
6. J.M. Chang, S.J. Hwang, H.T. Kuo, J.C. Tsai, J.Y. Guh, H.C. Chen, J.H. Tsai, and Y.H. Lai Fatal outcome after ingestion of star fruit (Averrhoa carambola) in uremic patients Am. J. Kidney Dis. 35 2000 189 193
7. M. Chebib, R.K. Duke, C.C. Duke, M. Connor, K.N. Mewett, and G.A.R. Johnston Convulsant actions of calycanthine Toxicol. Appl. Pharmacol. 190 2003 58 64
8. M. Chebib, and G.A. Johnston GABA-activated ligand gated ion channels: medicinal chemistry and molecular biology J. Med. Chem. 43 2000 1427 1447
9. C.L. Chen, H.C. Fang, K.J. Chou, J.S. Wang, and H.M. Chung Acute oxalate nephropathy after ingestion of star fruit Am. J. Kidney Dis. 37 2001 418 422
10. D.R. Curtis, A.W. Duggan, D. Felix, and G.A. Johnston GABA, bicuculline and central inhibition Nature 226 1970 1222 1224
11. S. Engelborghs, R. D'Hooge, and P.P. De Deyn Pathophysiology of epilepsy Acta Neurol. Belg. 100 2000 201 213
12. A.C. Ferraz, L.F. Pereira, R.L. Ribeirao, C. Wolfman, J.H. Medina, F.A. Scorza, N.F. Santos, E.A. Cavalheiro, and C. Da Cunha Ricinine-elicited seizures: a novel chemical model of convulsive seizures Pharmacol. Biochem. Behav. 65 2000 577 583
13. F. Fonnum Glutamate: a neurotransmitter in mammalian brain J. Neurochem. 42 1984 1 11
14. Garcia-Cairasco, N., Del Vecchio, F., Oliveira, J.A.C., Dantas, M., Moyses Neto, M., 2002. A video-EEG study of the neurotoxic effects of star fruit (Averrhoa carambola) juice ingestion in animals with renal failure. In: ERA-EDTA Congress, Copenhagem.
15. E.G. Gray, and V.P. Whittaker The isolation of nerve ending from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation J. Anat. 96 1962 79 87
16. E.F. Hartree Determination of protein: a modification of the Lowry method that gives a linear photometric response Anal. Biochem. 48 1972 422 427
17. J.R. Inglefield, J.M. Perry, and R.D. Schwartz Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus Hippocampus 5 1995 460 468
18. G.A.R. Johnston GABAA receptor pharmacology Pharmacol. Ther. 69 1996 173 198
19. J.P. Leite, N. Garcia-Cairasco, and E.A. Cavalheiro New insights from the use of pilocarpine and kainate models Epilepsy Res. 50 2002 93 103
20. K.Y. Lo, G.M.W. Tong, P.N. Wong, S.K. Mak, and A.K.M. Wong Persistent hiccup in a continuous ambulatory peritoneal dialysis patient following ingestion of star fruit Hong Kong J. Nephrol. 3 2001 45 46
21. O.H. Lowry, N.J. Rosenbrouch, A.L. Farr, and R.J. Randall Protein measurement with the folin phenol reagent J. Biol. Chem. 193 1951 265 275
22. L.C. Martin, J.S.T. Caramori, P. Barreti, and V.A. Soares Intractable hiccups induced by carambola (Averrhoa carambola) ingestion in patients with end stage renal failure J. Bras. Nefrol. 15 1993 92 94
23. M.F. Moraes, F. Del Vecchio, V.C. Terra, and N. Garcia-Cairasco Time evolution of acoustic 'information' processing in the mesencephalon of Wistar rats Neurosci. Lett. 284 2000 13 16
24. M. Moyses-Neto, F. Robl, and J. Coutinho-Netto Intoxication by star fruit (Averrhoa carambola) in six dialysis patients? Nephrol. Dial. Transplant. 13 1998 570 572
25. M. Moyses-Neto, J.A.C. Costa, N. Garcia-Cairasco, J. Coutinho-Netto, B. Nakagawa, and M. Dantas Intoxication by star fruit (Averrhoa carambola) in 32 uraemic patients: treatment and outcome Nephrol. Dial. Transplant. 18 2003 120 125
26. C.K. Muir, and C.K. Lam Depressant action of Averrhoa carambola Med. J. Malaysia XXXIV 1980 279 280
27. C.A. Paula, M.V. Sousa, M.C.O. Salgado, and E. Oliveira Purification and substrate specificity of an angiotensin converting elastase-2 from the rat mesenteric arterial bed perfusate Biochim. Biophys. Acta 1388 1998 227 238
28. G. Paxinos, and C.H. Watson The Rat Brain in Stereotaxic Coordinates 1998 Academic Press New York p. 256
29. S.V. Sampaio, C.J. Laure, and J.R. Giglio Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus Toxicon 21 1983 265 277
30. P. Sanz, and R. Reig Clinical and pathological findings in fatal plant oxalosis. A review Am. J. Foren. Med. Pathol. 13 1992 342 345
31. K. Satake, T. Okuyama, M. Ohashi, and T. Shinoda The spectrophotometric determination of amine, amino acid and peptide with 2,4,6-trinitrobenzene 1-sulfonic acid J. Biochem. 47 1960 654 660
32. K.C. Tse, P.S. Yip, M.F. Lam, B.Y. Choy, F.K. Li, S.L. Lui, W.K. Lo, T.M. Chan, and K.N. Lai Star fruit intoxication in uraemic patients: case series and review of the literature Int. Med. J. 33 2003 314 316
33. - current in acutely dissociated rat hippocampal CA1 neurons Brain Res. 889 2001 174 180
34. S.J. Wang, and T.S. Sihra Opposing facilitatory and inhibitory modulation of glutamate release elicited by cAMP production in cerebrocortical nerve terminals (synaptosomes) Neuropharmacology 44 2003 686 697
35. C.C. Wu, J.C. Denq, W.S. Tsai, and S.H. Lin Star fruit-induced neurotoxicity in two patients with chronic renal failure J. Med. Sci. 22 2002 75 78
36. H.J. Yap, Y.C. Chen, J.T. Fang, and C.C. Huang Star fruit: a neglected but serious fruit intoxication in chronic renal failure Dial. Transplant. 31 2002 564 597
37. S.R. Zukin, A.B. Young, and S.H. Snyder Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system Proc. Natl. Acad. Sci. U.S.A. 71 1974 4802 4807