Inverse correlation between frontal lobe and cerebellum sizes in children with autism

Brain

Volumn 123, Issue 4, 2000, Pages 836-844

  Carper, Ruth A ^a,b   Courchesne, Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Lab Res on the Neurosci of Autism   (United States)

Author keywords

Autism; Cerebrum; Magnetic resonance imaging; Neuroanatomy; Vermis

Indexed keywords

ARTICLE; AUTISM; BRAIN SIZE; CEREBELLUM; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FRONTAL LOBE; HUMAN; MALE; NEUROANATOMY; PRIORITY JOURNAL;

EID: 0034122498     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/123.4.836     Document Type: Article

References (50)

1. Akshoomoff NA, Courchesne E. ERP evidence for a shifting attention deficit in patients with damage to the cerebellum. J Cogn Neurosci 1994; 6: 388-99.
2. Allen G, Buxton RB, Wong EC, Courchesne E. Attentional activation of the cerebellum independent of motor involvement. Science 1997; 275: 1940-3.
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-IV. 4th ed. Washington (DC): American Psychiatric Association; 1994.
4. Arthur G. Arthur Adaptation of the Leiter International Performance Scale. Wood Dale (IL): Stoelting; 1980.
5. Bailey A, Luthert P, Dean A, Harding B, Janota I, Montgomery M, et al. A clinicopathological study of autism. Brain 1998; 121: 889-905.
6. Bauman M, Kemper TL. Histoanatomic observations of the brain in early infantile autism. Neurology 1985; 35: 866-74.
7. Ciesielski KT, Courchesne E, Elmasian R. Effects of focused selective attention tasks on event-related potentials in autistic and normal individuals. Electroencephalogr Clin Neurophysiol 1990; 75: 207-20.
8. Ciranni MA, Dodson CS, Shimamura AP. Impaired source memory in cerebellar patients [abstract], Soc Neurosci Abstr 1998; 24: 2115.
9. Courchesne E. Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. [Review]. Curr Opin Neurobiol 1997; 7: 269-78.
10. Courchesne E, Kilman BA, Galambos R, Lincoln AJ. Autism: processing of novel auditory information assessed by event-related brain potentials. Electroencephalogr Clin Neurophysiol 1984; 59: 238-48.
11. Courchesne E, Townsend J, Saitoh O. The brain in infantile autism: posterior fossa structures are abnormal. Neurology 1994; 44: 214-23.
12. Courtney SM, Ungerleider LG, Keil K, Haxby JV. Object and spatial visual working memory activate separate neural systems in human cortex. Cereb Cortex 1996; 6: 39-49.
13. Damasio AR, Maurer RG. A neurological model for childhood autism. Arch Neurol 1978; 35: 777-86.
14. Dawson G, Klinger LG, Panagiotides H, Lewy A, Castelloe P. Subgroups of autistic children based on social behavior display distinct patterns of brain activity. J Abnorm Child Psychol 1995; 23: 569-83.
15. Desmond JE, Gabrieli JD, Wagner AD, Ginier BL, Glover GH. Lobular patterns of cerebellar activation in verbal working-memory and finger-tapping tasks as revealed by functional MRI. J Neurosci 1997; 17: 9675-85.
16. Dunn LM, Dunn LM. Peabody Picture Vocabulary Test-revised. Circle Pines (MN): American Guidance Service: 1981.
17. George MS, Costa DC, Kouris K, Ring HA, Ell PJ. Cerebral blood flow abnormalities in adults with infantile autism. J Nerv Ment Dis 1992; 180: 413-7.
18. Grafman J, Litvan I, Massaquoi S, Stewart M, Sirigu A, Hallett M. Cognitive planning deficit in patients with cerebellar atrophy. Neurology 1992; 42: 1493-6.
19. Guerin P, Lyon G, Barthelemy C, Sostak E, Chevrollier V, Carreau B, et al. Neuropathological study of a case of autistic syndrome with severe mental retardation. Dev Med Child Neurol 1996; 38: 203-11.
20. Harris NS, Courchesne E, Townsend J, Carper RA, Lord C. Neuroanatomic contributions to slowed orienting of attention in children with autism. Cog Brain Res 1999; 8: 61-71.
21. Hashimoto T, Tayama M, Murakawa K, Yoshimoto T, Miyazaki M, Harada M, et al. Development of the brainstem and cerebellum in autistic patients. J Autism Dev Disord 1995; 25: 1-18.
22. Hughes C, Russell J, Robbins TW. Evidence for executive dysfunction in autism. Neuropsychologia 1994; 32: 477-92.
23. Jackson EF, Narayana PA, Falconer JC. Reproducibility of nonparametric feature map segmentation for determination of normal human intracranial volumes with MR imaging data. J Magn Reson Imaging 1994; 4:692-700.
24. Killackey HP. Neocortical expansion: an attempt toward relating phytogeny and ontogeny. J Cogn Neurosci 1990; 2: 1-17.
25. Lincoln AJ, Allen M, Piacentini A. The assessment and interpretation of intellectual abilities in people with autism. In: Schopler E, Mesibov GB, editors. Learning and cognition in autism. New York: Plenum Press, 1994. p. 89-117.
26. Lord C, Rutter M, Goode S, Heemsbergen J, Jordan H, Mawhood L, et al. Autism Diagnostic Observation Schedule: a standardized observation of communicative and social behavior. J Autism Dev Disord 1989; 19: 185-212.
27. Lord C, Rutter M, Le Couteur A. Autism Diagnostic Interview -Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994; 24: 659-85.
28. Martin A, Haxby JV, Lalonde FM, Wiggs CL, Ungerleider LG. Discrete cortical regions associated with knowledge of color and knowledge of action. Science 1995; 270: 102-5.
29. Matsumae M, Kikinis R, Morocz IA, Lorenzo AV, Sandor T, Albert MS, et al. Age-related changes in intracranial compartment volumes in normal adults assessed by magnetic resonance imaging. J Neurosurg 1996; 84: 982-91.
30. Middleton FA, Strick PL. Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function. Science 1994; 266: 458-61.
31. Müller R-A, Courchesne E. The duplicity of plasticity: a conceptual approach to the study of early lesions and developmental disorders. In: Ernst M, Rumsey J, editors. The foundation and future of functional neuroimaging in child psychiatry. Cambridge, UK: Cambridge University Press; 2000.
32. Murakami JW. Courchesne E, Press GA, Yeung-Courchesne R, Hesselink JR. Reduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autism. Arch Neurol 1989; 46: 689-94.
33. Pennington BF, Ozonoff S. Executive functions and developmental psychopathology. [Review]. J Child Psychol Psychiatry 1996; 37: 51-87.
34. Quartz SR, Sejnowski TJ. The neural basis of cognitive development: a constructivist manifesto. Behav Brain Sci 1997; 20: 537-56.
35. Rumsey JM, Hamburger SD. Neuropsychological divergence of high-level autism and severe dyslexia. J Autism Dev Disord 1990; 20: 155-68.
36. Sadato N, Pascual-Leone A, Grafman J, Ibañez V, Deiber MP, Dold G, et al. Activation of the primary visual cortex by Braille reading in blind subjects. Nature 1996; 380: 526-8.
37. Sadato N, Pascual-Leone A, Grafman J, Deiber MP. Ibañez V, Hallett M. Neural networks for Braille reading by the blind. Brain 1998; 121: 1213-29.
38. Sasaki K, Jinnai K, Gemba H, Hashimoto S, Mizuno N. Projection of the cerebellar dentate nucleus onto the frontal association cortex in monkeys. Exp Brain Res 1979; 37: 193-8.
39. Schmahmann JD, Pandya DN. Anatomic organization of the basilar pontine projections from prefrontal cortices in rhesus monkey. [Review]. J Neurosci 1997; 17: 438-58.
40. Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome. Brain 1998; 121: 561-79.
41. Schopler E, Reichler RJ, Renner BR. Childhood Autism Rating Scale. Los Angeles: Western Psychological Services; 1988.
42. Thorndike RL, Hagen EP, Sattler JM. The Stanford-Binet Intelligence Scale. 4th ed. Chicago (IL): Riverside Publishing Company; 1986.
43. Townsend J, Harris NS, Courchesne E. Visual attention abnormalities in autism: delayed orienting to location. J Int Neuropsychol Soc 1996; 2: 541-50.
44. Uhl F, Franzen P, Podreka I, Steiner M, Deecke L. Increased regional cerebral blood flow in inferior occipital cortex and cerebellum of early blind humans. Neurosci Lett 1993; 150: 162-4.
45. Vannier MW, Butterfield RL, Jordan D, Murphy WA, Levitt RG, Gado M. Multispectral analysis of magnetic resonance images. Radiology 1985; 154: 221-4.
46. Wechsler D. Wechsler Intelligence Scale for Children. 3rd ed. San Antonio (TX): Psychological Corporation; 1991.
47. Westerfield M, Townsend J, Covington J, Makeig S, Sejnowski TJ, Courchesne E. Independent components of the late positive event-related potential in a visual spatial attention task: normal and clinical subject differences [abstract]. Soc Neurosci Abstr 1998; 24: 507.
48. Williams RS, Hauser SL, Purpura DP, DeLong GR, Swisher CN. Autism and mental retardation: neuropathologic studies performed in four retarded persons with autistic behavior. Arch Neurol 1980; 37: 749-53.
49. Zilbovicius M, Garreau B, Samson Y, Remy P, Barthélémy C, Syrota A, et al. Delayed maturation of the frontal cortex in childhood autism. Am J Psychiatry 1995; 152: 248-52.
50. Zilles K. Cortex. In: Paxinos G, editor. The human nervous system. San Diego (CA): Academic Press; 1990. p. 757-802.